Nigel Mackman

Division of Hematology, University of North Carolina at Chapel Hill

Affiliated withUniversity of North Carolina at Chapel Hill

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2023

Other Publications

Article	Year
Tissue-specific hemostasis: role of tissue factor. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 18088348	2008
Tissue factor and factor VIIa: understanding the molecular mechanism. Thrombosis research\| PubMed ID: 18691490	2008
Vascular smooth muscle-derived tissue factor is critical for arterial thrombosis after ferric chloride-induced injury. Blood\| PubMed ID: 18931346	2009
Tissue factor regulation by epidermal growth factor receptor and epithelial-to-mesenchymal transitions: effect on tumor initiation and angiogenesis. Cancer research\| PubMed ID: 19074872	2008
Bleeding hearts. Blood\| PubMed ID: 19147791	2009
Cardiovascular disease in women. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 19221202	2009
Venous thromboembolism: risk factors, biomarkers, and treatment. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 19228601	2009
Detection of endogenous tissue factor levels in plasma using the calibrated automated thrombogram assay. Thrombosis research\| PubMed ID: 19345399	2010
The role of tissue factor and factor VIIa in hemostasis. Anesthesia and analgesia\| PubMed ID: 19372318	2009
On the trail of microparticles. Circulation research\| PubMed ID: 19390059	2009
Role of tissue factor in cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 19738116	2009
Increased microparticle tissue factor activity in cancer patients with Venous Thromboembolism. Thrombosis research\| PubMed ID: 19854471	2010
Tissue factor: past, present, and future. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 19923557	2009
DVT: a new era in anticoagulant therapy. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 20139354	2010
Wound healing in hemophilia B mice and low tissue factor mice. Thrombosis research\| PubMed ID: 20170942	2010
Cellular sources of tissue factor in endotoxemia and sepsis. Thrombosis research\| PubMed ID: 20185165	2010
Venous thromboembolism in multiple myeloma: current perspectives in pathogenesis. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 20385482	2010
Hematopoietic and nonhematopoietic cell tissue factor activates the coagulation cascade in endotoxemic mice. Blood\| PubMed ID: 20410508	2010
Tissue factor and thrombosis: The clot starts here. Thrombosis and haemostasis\| PubMed ID: 20539911	2010
Elevated tissue factor expression contributes to exacerbated diabetic nephropathy in mice lacking eNOS fed a high fat diet. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 20626618	2010
Protease-activated receptor 2 deficiency reduces cardiac ischemia/reperfusion injury. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 20724699	2010
Protease-activated receptors mediate crosstalk between coagulation and fibrinolysis. Blood\| PubMed ID: 20736455	2010
Balancing clotting. Blood\| PubMed ID: 20829379	2010
Tissue factor and tissue factor pathway inhibitor as key regulators of global hemostasis: measurement of their levels in coagulation assays. Seminars in thrombosis and hemostasis\| PubMed ID: 20978997	2010
MPs or ICs? Blood\| PubMed ID: 21273325	2011
Protease-activated receptors and myocardial infarction. IUBMB life\| PubMed ID: 21438116	2011
Microparticles in hemostasis and thrombosis. Circulation research\| PubMed ID: 21566224	2011
Monocytic microparticles activate endothelial cells in an IL-1β-dependent manner. Blood\| PubMed ID: 21700772	2011
Anthracycline treatment of the human monocytic leukemia cell line THP-1 increases phosphatidylserine exposure and tissue factor activity. Thrombosis research\| PubMed ID: 21762960	2012
Regulation of thrombin-induced plasminogen activator inhibitor-1 in 4T1 murine breast cancer cells. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis\| PubMed ID: 21799402	2011
Protease-activated receptor 1 and hematopoietic cell tissue factor are required for hepatic steatosis in mice fed a Western diet. The American journal of pathology\| PubMed ID: 21907177	2011
Blood coagulation and blood vessel development: is tissue factor the missing link? Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 22011746	2011
Comment on "tissue factor-dependent chemokine production aggravates experimental colitis". Molecular medicine (Cambridge, Mass.)\| PubMed ID: 22027905	2011
Defining MAP3 kinases required for MDA-MB-231 cell tumor growth and metastasis. Oncogene\| PubMed ID: 22139075	2012
Effect of PAR-2 Deficiency in Mice on KC Expression after Intratracheal LPS Administration. Journal of signal transduction\| PubMed ID: 22175012	2011
Myeloid cell tissue factor does not contribute to venous thrombogenesis in an electrolytic injury model. Thrombosis research\| PubMed ID: 22192154	2011
Tissue factor in health and disease. Frontiers in bioscience (Elite edition)\| PubMed ID: 22201878	2012
Monocyte tissue factor-dependent activation of coagulation in hypercholesterolemic mice and monkeys is inhibited by simvastatin. The Journal of clinical investigation\| PubMed ID: 22214850	2012
Mouse models, risk factors, and treatments of venous thrombosis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 22345592	2012
PF4/heparin-antibody complex induces monocyte tissue factor expression and release of tissue factor positive microparticles by activation of FcγRI. Blood\| PubMed ID: 22394597	2012
Sources of tissue factor that contribute to thrombosis after rupture of an atherosclerotic plaque. Thrombosis research\| PubMed ID: 22444158	2012
Monocytes, neutrophils, and platelets cooperate to initiate and propagate venous thrombosis in mice in vivo. The Journal of experimental medicine\| PubMed ID: 22451716	2012
Tumor-derived tissue factor activates coagulation and enhances thrombosis in a mouse xenograft model of human pancreatic cancer. Blood\| PubMed ID: 22547577	2012
β-adrenergic receptor stimulation transactivates protease-activated receptor 1 via matrix metalloproteinase 13 in cardiac cells. Circulation\| PubMed ID: 22610965	2012
Tissue factor promotes activation of coagulation and inflammation in a mouse model of sickle cell disease. Blood\| PubMed ID: 22661702	2012
New insights into the mechanisms of venous thrombosis. The Journal of clinical investigation\| PubMed ID: 22751108	2012
P2X7 regulation of macrophage tissue factor activity and microparticle generation. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 22759201	2012
Dysregulated coagulation associated with hypofibrinogenaemia and plasma hypercoagulability: implications for identifying coagulopathic mechanisms in humans. Thrombosis and haemostasis\| PubMed ID: 22836883	2012
Role of tissue factor in atherothrombosis. Current atherosclerosis reports\| PubMed ID: 22886473	2012
Hepatocyte tissue factor activates the coagulation cascade in mice. Blood\| PubMed ID: 23305736	2013
Platelet ITAM signaling is critical for vascular integrity in inflammation. The Journal of clinical investigation\| PubMed ID: 23348738	2013
Microvesicles as risk markers for venous thrombosis. Expert review of hematology\| PubMed ID: 23373784	2013
PAR-1 contributes to the innate immune response during viral infection. The Journal of clinical investigation\| PubMed ID: 23391721	2013
Hyperlipidemia, tissue factor, coagulation, and simvastatin. Trends in cardiovascular medicine\| PubMed ID: 24016468	2014
Coagulation, protease-activated receptors, and viral myocarditis. Journal of cardiovascular translational research\| PubMed ID: 24203054	2014
Protease activated receptor-2 contributes to heart failure. PloS one\| PubMed ID: 24312345	2013
The antithrombotic effects of statins. Annual review of medicine\| PubMed ID: 24422578	2014
Differential contribution of FXa and thrombin to vascular inflammation in a mouse model of sickle cell disease. Blood\| PubMed ID: 24449213	2014
Circulating microparticle tissue factor activity is increased in patients with cirrhosis. Hepatology (Baltimore, Md.)\| PubMed ID: 24470301	2014
Tissue factor expression provokes escape from tumor dormancy and leads to genomic alterations. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24520174	2014
Multiple roles of the coagulation protease cascade during virus infection. Blood\| PubMed ID: 24632711	2014
Roles of PAR1 and PAR2 in viral myocarditis. Thrombosis research\| PubMed ID: 24759133	2014
Regulation of tissue factor gene expression in monocytes and endothelial cells: Thromboxane A2 as a new player. Vascular pharmacology\| PubMed ID: 24858575	2014
Factor XIII activity mediates red blood cell retention in venous thrombi. The Journal of clinical investigation\| PubMed ID: 24983320	2014
Fas-induced apoptosis increases hepatocyte tissue factor procoagulant activity in vitro and in vivo. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 25015658	2014
New targets for atherothrombosis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 25031326	2014
Inactivation of factor VIIa by antithrombin in vitro, ex vivo and in vivo: role of tissue factor and endothelial cell protein C receptor. PloS one\| PubMed ID: 25102166	2014
PARP-14 combines with tristetraprolin in the selective posttranscriptional control of macrophage tissue factor expression. Blood\| PubMed ID: 25293769	2014
Reduced thrombosis in Klkb1-/- mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor. Blood\| PubMed ID: 25339356	2015
Protective and pathological roles of tissue factor in the heart. Hamostaseologie\| PubMed ID: 25434707	2015
Role of tissue factor in Mycobacterium tuberculosis-induced inflammation and disease pathogenesis. PloS one\| PubMed ID: 25462128	2014
Excess of heme induces tissue factor-dependent activation of coagulation in mice. Haematologica\| PubMed ID: 25596265	2015
RASA3 is a critical inhibitor of RAP1-dependent platelet activation. The Journal of clinical investigation\| PubMed ID: 25705885	2015
Extracellular vesicles, tissue factor, cancer and thrombosis - discussion themes of the ISEV 2014 Educational Day. Journal of extracellular vesicles\| PubMed ID: 25773446	2015
A matched cross-sectional study of the association between circulating tissue factor activity, immune activation and advanced liver fibrosis in hepatitis C infection. BMC infectious diseases\| PubMed ID: 25884329	2015
Tissue Factor and Atherothrombosis. Journal of atherosclerosis and thrombosis\| PubMed ID: 26016513	2015
Platelet Inhibitors Reduce Rupture in a Mouse Model of Established Abdominal Aortic Aneurysm. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 26139462	2015
Hepatocyte tissue factor contributes to the hypercoagulable state in a mouse model of chronic liver injury. Journal of hepatology\| PubMed ID: 26325534	2016
Theme 2: Epidemiology, Biomarkers, and Imaging of Venous Thromboembolism (and postthrombotic syndrome). Thrombosis research\| PubMed ID: 26387734	2015
IL-13 Augments Compressive Stress-Induced Tissue Factor Expression in Human Airway Epithelial Cells. American journal of respiratory cell and molecular biology\| PubMed ID: 26407210	2016
Microvesicle Tissue Factor Activity and Interleukin-8 Levels are Associated with Mortality in Patients with Influenza A/H1N1 Infection. Critical care medicine\| PubMed ID: 26751613	2016
Thrombin-independent contribution of tissue factor to inflammation and cardiac hypertrophy in a mouse model of sickle cell disease. Blood\| PubMed ID: 26817955	2016
Editorial Commentary: Tissue factor expression by the endothelium: Coagulation or inflammation? Trends in cardiovascular medicine\| PubMed ID: 26850939	2016
The Clot Thickens in Atherosclerosis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 26912742	2016
Measurement of microparticle tissue factor activity in clinical samples: A summary of two tissue factor-dependent FXa generation assays. Thrombosis research\| PubMed ID: 26916302	2016
Myeloid tissue factor does not modulate lung inflammation or permeability during experimental acute lung injury. Scientific reports\| PubMed ID: 26924425	2016
Tissue factor deficiency increases alveolar hemorrhage and death in influenza A virus-infected mice. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 26947929	2016
Antibody-based targeting of alternatively spliced tissue factor: a new approach to impede the primary growth and spread of pancreatic ductal adenocarcinoma. Oncotarget\| PubMed ID: 26967388	2016
Microvesicle-associated tissue factor procoagulant activity for the preoperative diagnosis of ovarian cancer. Thrombosis research\| PubMed ID: 26967531	2016
CalDAG-GEFI Deficiency Reduces Atherosclerotic Lesion Development in Mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 26988592	2016
Venous thrombosis. Nature reviews. Disease primers\| PubMed ID: 27189130	2015
Mouse models of venous thrombosis are not equal. Blood\| PubMed ID: 27231393	2016
Complying With the National Institutes of Health Guidelines and Principles for Rigor and Reproducibility: Refutations. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 27335467	2016
Protective and detrimental effects of neuroectodermal cell-derived tissue factor in mouse models of stroke. JCI insight\| PubMed ID: 27489885	2016
Thrombosis in Cancer: Research Priorities Identified by a National Cancer Institute/National Heart, Lung, and Blood Institute Strategic Working Group. Cancer research\| PubMed ID: 27527638	2016
A combined deficiency of tissue factor and PAR-4 is associated with fatal pulmonary hemorrhage in mice. Thrombosis research\| PubMed ID: 27586081	2016
Corrigendum to 'Microvesicle-associated tissue factor procoagulant activity for the preoperative diagnosis of ovarian cancer", [Thromb. Res. 141 (2016) 39-48]. Thrombosis research\| PubMed ID: 27640329	2016
Corrigendum to "Measurement of microparticle tissue factor activity in clinical samples: A summary of two tissue factor-dependent FXa generation assays" [Thromb. Res. 139 (2016) 90-97]. Thrombosis research\| PubMed ID: 27676256	2016
Letter to Editor response: Endothelial cell tissue factor and coagulation. Trends in cardiovascular medicine\| PubMed ID: 27769630	2017
Protease-Activated Receptor 1 Enhances Poly I:C Induction of the Antiviral Response in Macrophages and Mice. Journal of innate immunity\| PubMed ID: 27820939	2017
Protease-Activated Receptor 1 Contributes to Angiotensin II-Induced Cardiovascular Remodeling and Inflammation. Cardiology\| PubMed ID: 27880950	2017
Erratum to "A combined deficiency of tissue factor and PAR-4 is associated with fatal pulmonary hemorrhage in mice" [Thromb. Res. 146 (2016) 46-50]. Thrombosis research\| PubMed ID: 27890308	2017
Anticoagulation increases alveolar hemorrhage in mice infected with influenza A. Physiological reports\| PubMed ID: 28003564	2016
Tissue Factor: Catch Me If You Can! Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 28029321	2017
Detection of tissue factor-positive extracellular vesicles by laser scanning confocal microscopy. Thrombosis research\| PubMed ID: 28043041	2017
Methodological Guidelines to Study Extracellular Vesicles. Circulation research\| PubMed ID: 28495994	2017
A monocyte-TNF-endothelial activation axis in sickle transgenic mice: Therapeutic benefit from TNF blockade. American journal of hematology\| PubMed ID: 28699284	2017
Thrombin promotes diet-induced obesity through fibrin-driven inflammation. The Journal of clinical investigation\| PubMed ID: 28737512	2017
Cancer-associated pathways and biomarkers of venous thrombosis. Blood\| PubMed ID: 28807983	2017
Caspase Inhibition Reduces Hepatic Tissue Factor-Driven Coagulation In Vitro and In Vivo. Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 29228388	2018
Mouse models of cancer-associated thrombosis. Thrombosis research\| PubMed ID: 29306575	2018
Association of D-dimer with Plaque Characteristics and Plasma Biomarkers of Oxidation-Specific Epitopes in Stable Subjects with Coronary Artery Disease. Journal of cardiovascular translational research\| PubMed ID: 29344841	2018
Distinct Pathogenesis of Pancreatic Cancer Microvesicle-Associated Venous Thrombosis Identifies New Antithrombotic Targets In Vivo. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 29419408	2018
Tissue Factor: An Essential Mediator of Hemostasis and Trigger of Thrombosis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 29437578	2018
Dual Anticoagulant and Antiplatelet Therapy for Coronary Artery Disease and Peripheral Artery Disease Patients. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 29449336	2018
Comparison of microvesicle tissue factor activity in non-cancer severely ill patients and cancer patients. Thrombosis research\| PubMed ID: 29539580	2018
Platelet Signaling Pathways and New Inhibitors. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 29563117	2018
PAR2 (Protease-Activated Receptor 2) Deficiency Attenuates Atherosclerosis in Mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 29599135	2018
Extracellular vesicles exposing tissue factor for the prediction of venous thromboembolism in patients with cancer: A prospective cohort study. Thrombosis research\| PubMed ID: 29656167	2018
Tissue factor and oxidative stress. Blood\| PubMed ID: 29748170	2018
Response by Daugherty et al to Letter Regarding Article, "Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies: A Statement From the Council". Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 29793996	2018
The factor Xa inhibitor rivaroxaban reduces cardiac dysfunction in a mouse model of myocardial infarction. Thrombosis research\| PubMed ID: 29843086	2018
The uremic solute-AHR-tissue factor axis in vascular cells, mouse models and thrombosis in chronic kidney disease patients. Annals of translational medicine\| PubMed ID: 30023388	2018
Protease-activated receptor 1 activation enhances doxorubicin-induced cardiotoxicity. Journal of molecular and cellular cardiology\| PubMed ID: 30098988	2018
Neutrophils, NETs, and immunothrombosis. Blood\| PubMed ID: 30262582	2018
Reporting Sex and Sex Differences in Preclinical Studies. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 30354222	2018
Low extracellular vesicle-associated tissue factor activity in patients with persistent lupus anticoagulant and a history of thrombosis. Annals of hematology\| PubMed ID: 30467688	2019
mTOR kinase inhibition reduces tissue factor expression and growth of pancreatic neuroendocrine tumors. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 30472780	2019
Roles of Coagulation Proteases and PARs (Protease-Activated Receptors) in Mouse Models of Inflammatory Diseases. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 30580574	2019
Measurement of tissue factor activity in extracellular vesicles from human plasma samples. Research and practice in thrombosis and haemostasis\| PubMed ID: 30656275	2019
Intrinsic Pathway of Coagulation and Thrombosis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 30700128	2019
A clinical practice-based evaluation of the RIETE score in predicting occult cancer in patients with venous thromboembolism. Journal of thrombosis and thrombolysis\| PubMed ID: 30739306	2019
Choosing a Mouse Model of Venous Thrombosis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 30786739	2019
Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice. Scientific reports\| PubMed ID: 30846818	2019
Choosing a mouse model of venous thrombosis: a consensus assessment of utility and application. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 30927321	2019
Expression of factor V by resident macrophages boosts host defense in the peritoneal cavity. The Journal of experimental medicine\| PubMed ID: 31048328	2019
Neutrophils and neutrophil extracellular traps enhance venous thrombosis in mice bearing human pancreatic tumors. Haematologica\| PubMed ID: 31048354	2020
Patients with severe orthohantavirus cardiopulmonary syndrome due to Sin Nombre Virus infection have increased circulating extracellular vesicle tissue factor and an activated coagulation sy... Thrombosis research\| PubMed ID: 31075699	2019
Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis. Immunity\| PubMed ID: 31076358	2019
Tissue Factor and Cancer: Regulation, Tumor Growth, and Metastasis. Seminars in thrombosis and hemostasis\| PubMed ID: 31096306	2019
Mitochondria Are a Subset of Extracellular Vesicles Released by Activated Monocytes and Induce Type I IFN and TNF Responses in Endothelial Cells. Circulation research\| PubMed ID: 31219742	2019
Cancer cell-derived tissue factor-positive extracellular vesicles: biomarkers of thrombosis and survival. Current opinion in hematology\| PubMed ID: 31261175	2019
Neutrophil Extracellular Traps: Villains and Targets in Arterial, Venous, and Cancer-Associated Thrombosis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 31315434	2019
Protease-activated receptor 4 protects mice from Coxsackievirus B3 and H1N1 influenza A virus infection. Cellular immunology\| PubMed ID: 31337508	2019
Rivaroxaban does not affect growth of human pancreatic tumors in mice. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 31393055	2019
Increasing the sensitivity of the human microvesicle tissue factor activity assay. Thrombosis research\| PubMed ID: 31450010	2019
Cell type-specific mechanisms coupling protease-activated receptor-1 to infectious colitis pathogenesis. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 31539206	2020
How useful are ferric chloride models of arterial thrombosis? Platelets\| PubMed ID: 31608756	2020
Circulating Extracellular Vesicle Tissue Factor Activity During Orthohantavirus Infection Is Associated With Intravascular Coagulation. The Journal of infectious diseases\| PubMed ID: 31722433	2020
Plasma Kallikrein Contributes to Coagulation in the Absence of Factor XI by Activating Factor IX. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 31766871	2020
Update from the laboratory: mechanistic studies of pathways of cancer-associated venous thrombosis using mouse models. Hematology. American Society of Hematology. Education Program\| PubMed ID: 31808871	2019
Bacterial Endotoxin Activates the Coagulation Cascade through Gasdermin D-Dependent Phosphatidylserine Exposure. Immunity\| PubMed ID: 31836429	2019
Annual Report on Sex in Preclinical Studies: Publications in 2018. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 31869272	2020
Differential roles of factors IX and XI in murine placenta and hemostasis under conditions of low tissue factor. Blood advances\| PubMed ID: 31935292	2020
Therapeutic strategies for thrombosis: new targets and approaches. Nature reviews. Drug discovery\| PubMed ID: 32132678	2020
Quantification of Viral and Host Biomarkers in the Liver of Rhesus Macaques: A Longitudinal Study of Zaire Ebolavirus Strain Kikwit (EBOV/Kik). The American journal of pathology\| PubMed ID: 32275904	2020
Chemotherapy Increases Stroke: Fact or Fiction? Thrombosis and haemostasis\| PubMed ID: 32289856	2020
Effect of chemotherapy and longitudinal analysis of circulating extracellular vesicle tissue factor activity in patients with pancreatic and colorectal cancer. Research and practice in thrombosis and haemostasis\| PubMed ID: 32548563	2020
Quantification of citrullinated histones: Development of an improved assay to reliably quantify nucleosomal H3Cit in human plasma. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 32654410	2020
Coagulation Abnormalities and Thrombosis in Patients Infected With SARS-CoV-2 and Other Pandemic Viruses. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 32657623	2020
Tissue factor in atherosclerosis and atherothrombosis. Atherosclerosis\| PubMed ID: 32674807	2020
Evaluation of different commercial antibodies for their ability to detect human and mouse tissue factor by western blotting. Research and practice in thrombosis and haemostasis\| PubMed ID: 32864552	2020
Thrombin-PAR1 signaling in pancreatic cancer promotes an immunosuppressive microenvironment. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 33064371	2021
Model-dependent contributions of FXII and FXI to venous thrombosis in mice. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 33094904	2020
Description of the first mutation in the human tissue factor gene associated with a bleeding tendency. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 33225609	2021
Patients With COVID-19 Have Elevated Levels of Circulating Extracellular Vesicle Tissue Factor Activity That Is Associated With Severity and Mortality-Brief Report. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 33267656	2021
Circulating Markers of Neutrophil Extracellular Traps Are of Prognostic Value in Patients With COVID-19. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 33267662	2021
PAR1 regulation of CXCL1 expression and neutrophil recruitment to the lung in mice infected with influenza A virus. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 33346953	2021
New Cellular Source of TF (Tissue Factor)-Positive Extracellular Vesicles in the Circulation. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 33356372	2021
Elevated factor V activity and antigen levels in patients with Covid-19 are related to disease severity and 30-day mortality. American journal of hematology\| PubMed ID: 33393103	2021
Plasminogen activator inhibitor 1 and venous thrombosis in pancreatic cancer. Blood advances\| PubMed ID: 33496742	2021
The Intrinsic Pathway does not Contribute to Activation of Coagulation in Mice Bearing Human Pancreatic Tumors Expressing Tissue Factor. Thrombosis and haemostasis\| PubMed ID: 33498089	2021
Natural IgM antibodies inhibit microvesicle-driven coagulation and thrombosis. Blood\| PubMed ID: 33512411	2021
Prothrombotic changes in patients with COVID-19 are associated with disease severity and mortality. Research and practice in thrombosis and haemostasis\| PubMed ID: 33537537	2021
Sustained prothrombotic changes in COVID-19 patients 4 months after hospital discharge. Blood advances\| PubMed ID: 33560386	2021
Cancer Therapy-Associated Thrombosis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 33567864	2021
Platelets and viruses. Platelets\| PubMed ID: 33615982	2021
Prognostic value of circulating markers of neutrophil activation, neutrophil extracellular traps, coagulation and fibrinolysis in patients with terminal cancer. Scientific reports\| PubMed ID: 33658563	2021
Glioblastoma cell populations with distinct oncogenic programs release podoplanin as procoagulant extracellular vesicles. Blood advances\| PubMed ID: 33720339	2021
COVID-19 is Associated with an Acquired Factor XIII Deficiency. Thrombosis and haemostasis\| PubMed ID: 33742434	2021
Effects of storage and leukocyte reduction on the concentration and procoagulant activity of extracellular vesicles in canine packed red cells. Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)\| PubMed ID: 33751799	2021
Comparison of the coagulopathies associated with COVID-19 and sepsis. Research and practice in thrombosis and haemostasis\| PubMed ID: 34027292	2021
Myeloid cell-derived coagulation tissue factor is associated with renal tubular damage in mice fed an adenine diet. Scientific reports\| PubMed ID: 34108522	2021
Soluble angiotensin-converting enzyme 2 is transiently elevated in COVID-19 and correlates with specific inflammatory and endothelial markers. Journal of medical virology\| PubMed ID: 34138483	2021
Inflammasome activation promotes venous thrombosis through pyroptosis. Blood advances\| PubMed ID: 34152402	2021
Cardiac Tissue Factor Regulates Inflammation, Hypertrophy, and Heart Failure in Mouse Model of Type 1 Diabetes. Diabetes\| PubMed ID: 34155039	2021
Cell type-specific roles of PAR1 in Coxsackievirus B3 infection. Scientific reports\| PubMed ID: 34253819	2021
Tissue Factor and Extracellular Vesicles: Activation of Coagulation and Impact on Survival in Cancer. Cancers\| PubMed ID: 34359742	2021
Tissue factor expression, extracellular vesicles, and thrombosis after infection with the respiratory viruses influenza A virus and coronavirus. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 34418279	2021
Hemostatic Biomarkers and Venous Thromboembolism Are Associated With Mortality and Response to Chemotherapy in Patients With Pancreatic Cancer. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 34470475	2021
Genetic deletion of platelet PAR4 results in reduced thrombosis and impaired hemostatic plug stability. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 34689407	2022
Platelet-Mediated NET Release Amplifies Coagulopathy and Drives Lung Pathology During Severe Influenza Infection. Frontiers in immunology\| PubMed ID: 34858432	2021
Myeloid Protease-Activated Receptor-2 Contributes to Influenza A Virus Pathology in Mice. Frontiers in immunology\| PubMed ID: 34925374	2021
Effect of heparanase inhibitor on tissue factor overexpression in platelets and endothelial cells induced by anti-β2-GPI antibodies: Comment from Mackman et al. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 34954879	2022
Web of Science's Citation Median Metrics Overcome the Major Constraints of the Journal Impact Factor. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 35109675	2022
Tissue factor and its procoagulant activity on cancer-associated thromboembolism in pancreatic cancer: Comment by Mackman et al. Cancer science\| PubMed ID: 35132733	2022
Cancer-associated venous thromboembolism. Nature reviews. Disease primers\| PubMed ID: 35177631	2022
Effect of combining aspirin and rivaroxaban on atherosclerosis in mice. Atherosclerosis\| PubMed ID: 35183904	2022
Evaluation of a new bead-based assay to measure levels of human tissue factor antigen in extracellular vesicles in plasma. Research and practice in thrombosis and haemostasis\| PubMed ID: 35284777	2022
Direct Oral Anticoagulants and Coronary Artery Disease. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 35296151	2022
Methods for the identification and characterization of extracellular vesicles in cardiovascular studies - from exosomes to microvesicles. Cardiovascular research\| PubMed ID: 35325061	2022
Therapeutic potential of granulocyte microvesicles in sepsis. Blood\| PubMed ID: 35420691	2022
Anticoagulant SERPINs: Endogenous Regulators of Hemostasis and Thrombosis. Frontiers in cardiovascular medicine\| PubMed ID: 35592395	2022
Circulating tissue factor-positive extracellular vesicles and their association with thrombosis in different diseases. Immunological reviews\| PubMed ID: 35708588	2022
Illustrated State-of-the-Art Capsules of the ISTH 2022 Congress. Research and practice in thrombosis and haemostasis\| PubMed ID: 35814801	2022
Measurement of tissue factor-positive extracellular vesicles in plasma: strengths and weaknesses of current methods. Current opinion in hematology\| PubMed ID: 35852819	2022
Markers of neutrophil activation and neutrophil extracellular traps in diagnosing patients with acute venous thromboembolism: A feasibility study based on two VTE cohorts. PloS one\| PubMed ID: 35901107	2022
Understanding COVID-19-associated coagulopathy. Nature reviews. Immunology\| PubMed ID: 35931818	2022
Hereditary angioedema is associated with an increased risk of venous thromboembolism. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 36053174	2022
Tissue Factor and COVID-19: An Update. Current drug targets\| PubMed ID: 36165519	2022
Neutrophil extracellular traps and cancer-associated thrombosis. Thrombosis research\| PubMed ID: 36210559	2022
Cardiovascular Disease and Thrombosis in HIV Infection. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 36453273	2023
Circulating Tumor Cells and Cancer-Associated Venous Thrombosis: A Missing Link. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 36453278	2023
Thrombin-mediated activation of PAR1 enhances doxorubicin-induced cardiac injury in mice. Blood advances\| PubMed ID: 36477178	2023
A novel mouse whole blood thrombin generation assay sensitive to FXI- and FIX-mediated amplification of coagulation. Blood advances\| PubMed ID: 36583671	2023
"Hereditary angioedema is associated with an increased risk of venous thromboembolism": reply. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 36695383	2023
C1 inhibitor deficiency enhances contact pathway-mediated activation of coagulation and venous thrombosis. Blood\| PubMed ID: 36701760	2023
Decreased Platelet Reactivity and Function in a Mouse Model of Human Pancreatic Cancer. Thrombosis and haemostasis\| PubMed ID: 36716775	2023
Loss of P2Y receptor desensitization does not impact hemostasis or thrombosis despite increased platelet reactivity in vitro. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 36958516	2023
"A rapid, sensitive, and specific assay to measure tissue factor activity based on chromogenic determination of thrombin generation": comment from Tanratana et al. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 36990515	2023
High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 37003465	2023
Tissue factor activity of small and large extracellular vesicles in different diseases. Research and practice in thrombosis and haemostasis\| PubMed ID: 37012986	2023
Mechanisms of cancer-associated thrombosis. Research and practice in thrombosis and haemostasis\| PubMed ID: 37122533	2023
Tissue factor-positive extracellular vesicles in plasma are not associated with venous thromboembolism in patients with ovarian cancer. Research and practice in thrombosis and haemostasis\| PubMed ID: 37128624	2023
Monocyte Tissue Factor Expression: Lipopolysaccharide Induction and Roles in Pathological Activation of Coagulation. Thrombosis and haemostasis\| PubMed ID: 37168007	2023
Evaluation of four commercial ELISAs to measure tissue factor in human plasma. Research and practice in thrombosis and haemostasis\| PubMed ID: 37275179	2023
Detection of tissue factor-positive extracellular vesicles using the ExoView R100 system. Research and practice in thrombosis and haemostasis\| PubMed ID: 37333992	2023
Tissue factor activates the coagulation cascade in mouse models of acute promyelocytic leukemia. Blood advances\| PubMed ID: 37450381	2023
Heat shock protein 47 and venous thrombosis: letting sleeping bears lie. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 37473845	2023
Neutrophil extracellular trap formation is an independent risk factor for occult cancer in patients presenting with venous thromboembolism. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 37479035	2023
APC-PAR1-R46 signaling limits CXCL1 expression during poly IC-induced airway inflammation in mice. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 37634652	2023
"C1-inhibitor levels and Venous Thromboembolism: Results from a Mendelian Randomization Study": comment from Grover et al. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 37739595	2023
"High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism": reply. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 37739598	2023
Regulation of von Willebrand factor by ADAMTS13 ameliorates lipopolysaccharide-induced lung injury in mice. International journal of hematology\| PubMed ID: 37759076	2023
Tissue factor pathway inhibitor is associated with risk of venous thromboembolism and all-cause mortality in patients with cancer. Haematologica\| PubMed ID: 37822244	2023
Mice expressing nonpolymerizable fibrinogen have reduced arterial and venous thrombosis with preserved hemostasis. Blood\| PubMed ID: 37832029	2023
Biomarkers of bleeding and venous thromboembolism in patients with acute leukemia. medRxiv : the preprint server for health sciences\| PubMed ID: 37905148	2023
Commentary: Tissue factor as a potential coagulative/vascular marker in relapsing-remitting multiple sclerosis. Frontiers in immunology\| PubMed ID: 38106419	2023
Tissue factor binds to and inhibits interferon-α receptor 1 signaling. Immunity\| PubMed ID: 38141610	2023