Lieping Chen

Yale Cancer Center, Yale School of Medicine

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 43	2013

Other Publications

Article	Year
Interleukin 4 receptor-directed cytotoxin therapy for human head and neck squamous cell carcinoma in animal models. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 11801570	2002
Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 11801689	2002
Blockade of LIGHT/LTbeta and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease. The Journal of clinical investigation\| PubMed ID: 11854328	2002
Reassessment of CD62L as a marker of pre-effector T cells in the tumor draining lymph nodes of head and neck cancer patients. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery\| PubMed ID: 11870350	2002
Provision of antigen and CD137 signaling breaks immunological ignorance, promoting regression of poorly immunogenic tumors. The Journal of clinical investigation\| PubMed ID: 11877473	2002
Immunotherapy of human papillomavirus-associated malignancies and the challenges posed by T-cell tolerance. Frontiers in bioscience : a journal and virtual library\| PubMed ID: 11897572	2002
Strategies for antigen loading of dendritic cells to enhance the antitumor immune response. Cancer research\| PubMed ID: 11912169	2002
Antibody gene therapy: old wine in a new bottle. Nature medicine\| PubMed ID: 11927934	2002
Ligand binding sites of inducible costimulator and high avidity mutants with improved function. The Journal of experimental medicine\| PubMed ID: 11956294	2002
Cutting edge: Expression of functional CD137 receptor by dendritic cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 11970964	2002
Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunity. Cancer research\| PubMed ID: 15705911	2005
Cutting edge: selective impairment of CD8+ T cell function in mice lacking the TNF superfamily member LIGHT. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 11994431	2002
Modulation of dendritic cell differentiation and maturation by decoy receptor 3. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 11994433	2002
Anti-4-1BB monoclonal antibody enhances rejection of large tumor burden by promoting survival but not clonal expansion of tumor-specific CD8+ T cells. Cancer research\| PubMed ID: 12067989	2002
Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion. Nature medicine\| PubMed ID: 12091876	2002
Immunoglobulin fusion proteins as a tool for evaluation of T-cell costimulatory molecules. Molecular biotechnology\| PubMed ID: 12102550	2002
Impaired infiltration of tumor-specific cytolytic T cells in the absence of interferon-gamma despite their normal maturation in lymphoid organs during CD137 monoclonal antibody therapy. Cancer research\| PubMed ID: 12154048	2002
Signaling through NK cell-associated CD137 promotes both helper function for CD8+ cytolytic T cells and responsiveness to IL-2 but not cytolytic activity. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12370353	2002
Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease. Nature medicine\| PubMed ID: 12426559	2002
Cross-linking the B7 family molecule B7-DC directly activates immune functions of dendritic cells. The Journal of experimental medicine\| PubMed ID: 12438431	2002
B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression. Blood\| PubMed ID: 12468426	2003
[Antitumor immunity elicited by 4-1BBL gene transfected Hepa1-6 in vivo]. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology\| PubMed ID: 12502438	2002
Costimulating aberrant T cell responses by B7-H1 autoantibodies in rheumatoid arthritis. The Journal of clinical investigation\| PubMed ID: 12569162	2003
Naturally occurring human IgM antibody that binds B7-DC and potentiates T cell stimulation by dendritic cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 12574348	2003
B7 family molecules are favorably positioned at the human maternal-fetal interface. Biology of reproduction\| PubMed ID: 12606489	2003
Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity. Nature medicine\| PubMed ID: 12704383	2003
Expression of the costimulatory molecule B7-H2 (inducible costimulator ligand) by human airway epithelial cells. American journal of respiratory cell and molecular biology\| PubMed ID: 12707012	2003
Characterization of antigen processing machinery and Survivin expression in tonsillar squamous cell carcinoma. Cancer\| PubMed ID: 12712472	2003
Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction. The Journal of experimental medicine\| PubMed ID: 12719480	2003
B7-H1 pathway and its role in the evasion of tumor immunity. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 12721664	2003
A simple and rapid vortex method for preparing antigen/adjuvant emulsions for immunization. Journal of immunological methods\| PubMed ID: 12738377	2003
B7-H4, a molecule of the B7 family, negatively regulates T cell immunity. Immunity\| PubMed ID: 12818165	2003
Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor. The Journal of experimental medicine\| PubMed ID: 12847135	2003
Differential binding properties of B7-H1 and B7-DC to programmed death-1. Biochemical and biophysical research communications\| PubMed ID: 12893276	2003
Cancer therapeutic monoclonal antibodies targeting lymphocyte co-stimulatory pathways. Current opinion in investigational drugs (London, England : 2000)\| PubMed ID: 12901227	2003
Autoimmune diabetes in HLA-DR3/DQ8 transgenic mice expressing the co-stimulatory molecule B7-1 in the beta cells of islets of Langerhans. International immunology\| PubMed ID: 12917255	2003
Human muscle cells express a B7-related molecule, B7-H1, with strong negative immune regulatory potential: a novel mechanism of counterbalancing the immune attack in idiopathic inflammatory ... FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12923066	2003
Ligation of CD137 receptor prevents and reverses established anergy of CD8+ cytolytic T lymphocytes in vivo. Blood\| PubMed ID: 12969968	2004
Blockade of B7-H1 suppresses the development of chronic intestinal inflammation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14530338	2003
B7-H1 blockade augments adoptive T-cell immunotherapy for squamous cell carcinoma. Cancer research\| PubMed ID: 14559843	2003
Genomic organization and expression analysis of B7-H4, an immune inhibitory molecule of the B7 family. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14568939	2003
Expression of the B7-related molecule B7-H1 by glioma cells: a potential mechanism of immune paralysis. Cancer research\| PubMed ID: 14612546	2003
Blocking the monocyte chemoattractant protein-1/CCR2 chemokine pathway induces permanent survival of islet allografts through a programmed death-1 ligand-1-dependent mechanism. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 14662900	2003
New B7 family members with positive and negative costimulatory function. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons\| PubMed ID: 14678029	2004
Immunology of B7-H1 and its roles in human diseases. International journal of hematology\| PubMed ID: 14686489	2003
Costimulation-based immunotherapy for head and neck cancer. Current treatment options in oncology\| PubMed ID: 14697154	2004
CD137 signaling interferes with activation and function of CD4+CD25+ regulatory T cells in induced tolerance to experimental autoimmune thyroiditis. Cellular immunology\| PubMed ID: 14746804	2003
Control of autoimmune diseases by the B7-CD28 family molecules. Current pharmaceutical design\| PubMed ID: 14754392	2004
Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection. The Journal of clinical investigation\| PubMed ID: 14991067	2004
B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes. Immunity\| PubMed ID: 15030776	2004
Structural and functional analysis of the costimulatory receptor programmed death-1. Immunity\| PubMed ID: 15030777	2004
Improving efficacy of interleukin-12-transfected dendritic cells injected into murine colon cancer with anti-CD137 monoclonal antibodies and alloantigens. International journal of cancer. Journal international du cancer\| PubMed ID: 15054868	2004
Strong synergy between mutant ras and HPV16 E6/E7 in the development of primary tumors. Oncogene\| PubMed ID: 15077191	2004
Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity. Nature reviews. Immunology\| PubMed ID: 15122199	2004
Selective suppression of dendritic cell functions by cigarette smoke extract. Chest\| PubMed ID: 15136445	2004
53BP1 is required for class switch recombination. The Journal of cell biology\| PubMed ID: 15159415	2004
Co-signaling molecules of the B7-CD28 family in positive and negative regulation of T lymphocyte responses. Microbes and infection / Institut Pasteur\| PubMed ID: 15207823	2004
Immunotherapeutic potential of B7-DC (PD-L2) cross-linking antibody in conferring antitumor immunity. Cancer research\| PubMed ID: 15256470	2004
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nature medicine\| PubMed ID: 15322536	2004
Interferon-beta enhances monocyte and dendritic cell expression of B7-H1 (PD-L1), a strong inhibitor of autologous T-cell activation: relevance for the immune modulatory effect in multiple s... Journal of neuroimmunology\| PubMed ID: 15342209	2004
B7-H3 enhances tumor immunity in vivo by costimulating rapid clonal expansion of antigen-specific CD8+ cytolytic T cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15494491	2004
Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15569934	2004
Cutting edge: Cbl-b: one of the key molecules tuning CD28- and CTLA-4-mediated T cell costimulation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 15585834	2004
Anti-CD137 mAb treatment inhibits experimental autoimmune uveitis by limiting expansion and increasing apoptotic death of uveitogenic T cells. Investigative ophthalmology & visual science\| PubMed ID: 15671287	2005
B7-H3 promotes acute and chronic allograft rejection. European journal of immunology\| PubMed ID: 15682454	2005
Therapeutic efficacy of MUC1-specific cytotoxic T lymphocytes and CD137 co-stimulation in a spontaneous breast cancer model. Breast disease\| PubMed ID: 15687707	2004
Microglial expression of the B7 family member B7 homolog 1 confers strong immune inhibition: implications for immune responses and autoimmunity in the CNS. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15758163	2005
Enhancement of CD4 and CD8 immunity by anti-CD137 (4-1BB) monoclonal antibodies during hepatitis C vaccination with recombinant adenovirus. Vaccine\| PubMed ID: 15855007	2005
In vivo costimulatory role of B7-DC in tuning T helper cell 1 and cytotoxic T lymphocyte responses. The Journal of experimental medicine\| PubMed ID: 15897272	2005
Constitutive and inducible expression of b7 family of ligands by human airway epithelial cells. American journal of respiratory cell and molecular biology\| PubMed ID: 15961727	2005
Role of B7-H1 and B7-H4 molecules in down-regulating effector phase of T-cell immunity: novel cancer escaping mechanisms. Frontiers in bioscience : a journal and virtual library\| PubMed ID: 15970540	2005
Cigarette smoke extract suppresses human dendritic cell function leading to preferential induction of Th-2 priming. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16081845	2005
Expression of functional B7-H2 and B7.2 costimulatory molecules and their prognostic implications in de novo acute myeloid leukemia. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16115907	2005
Renewed interest in cancer immunotherapy with the tumor necrosis factor superfamily molecules. Cancer immunology, immunotherapy : CII\| PubMed ID: 16187084	2006
Costimulatory molecule B7-H1 in primary and metastatic clear cell renal cell carcinoma. Cancer\| PubMed ID: 16208700	2005
T lymphocyte co-signaling pathways of the B7-CD28 family. Cellular & molecular immunology\| PubMed ID: 16212919	2004
Renal tubular epithelial cells modulate T-cell responses via ICOS-L and B7-H1. Kidney international\| PubMed ID: 16221208	2005
The many sounds of T lymphocyte silence. Immunologic research\| PubMed ID: 16234580	2005
B7-H1 (CD274) inhibits the development of herpetic stromal keratitis (HSK). FEBS letters\| PubMed ID: 16253242	2005
Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gamma-induced upregulation of B7-H1 (CD274). FEBS letters\| PubMed ID: 16413538	2006
Low surface expression of B7-1 (CD80) is an immunoescape mechanism of colon carcinoma. Cancer research\| PubMed ID: 16489051	2006
Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis. The Journal of clinical investigation\| PubMed ID: 16557300	2006
B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma. The Journal of experimental medicine\| PubMed ID: 16606666	2006
Reviving exhausted T lymphocytes during chronic virus infection by B7-H1 blockade. Trends in molecular medicine\| PubMed ID: 16650803	2006
Cutting edge: induction of B7-H4 on APCs through IL-10: novel suppressive mode for regulatory T cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16785496	2006
The role of leukemia-derived B7-H1 (PD-L1) in tumor-T-cell interactions in humans. Experimental hematology\| PubMed ID: 16797416	2006
Does decentralisation improve human resource management in the health sector? A case study from China. Social science & medicine (1982)\| PubMed ID: 16808993	2006
Inhibition of Th2-mediated allergic airway inflammatory disease by CD137 costimulation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 16818735	2006
Modulation of immune response by B7 family molecules in tumor microenvironments. Immunological investigations\| PubMed ID: 16916759	2006
Suppression of human T-cell responses to beta-cells by activation of B7-H4 pathway. Cell transplantation\| PubMed ID: 16970282	2006
Human bone marrow: a reservoir for "enhanced effector memory" CD8+ T cells with potent recall function. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17082586	2006
Selective targeting of the LIGHT-HVEM costimulatory system for the treatment of graft-versus-host disease. Blood\| PubMed ID: 17179227	2007
Filoviruses and the balance of innate, adaptive, and inflammatory responses. Viral immunology\| PubMed ID: 17201655	2006
Effects of specific immunotherapy on the B7 family of costimulatory molecules in allergic inflammation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17237444	2007
CD137 stimulation delivers an antigen-independent growth signal for T lymphocytes with memory phenotype. Blood\| PubMed ID: 17244673	2007
Immunostimulatory monoclonal antibodies for cancer therapy. Nature reviews. Cancer\| PubMed ID: 17251916	2007
Interaction between B7-H1 and PD-1 determines initiation and reversal of T-cell anergy. Blood\| PubMed ID: 17289811	2007
Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17371976	2007
Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells. Blood\| PubMed ID: 17392506	2007
The new B7s: playing a pivotal role in tumor immunity. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 17414316	2007
B7-H1 up-regulation on myeloid dendritic cells significantly suppresses T cell immune function in patients with chronic hepatitis B. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 17475895	2007
LIGHT-related molecular network in the regulation of innate and adaptive immunity. Immunologic research\| PubMed ID: 17496344	2007
How Ebola and Marburg viruses battle the immune system. Nature reviews. Immunology\| PubMed ID: 17589545	2007
Relationship between B7-H4, regulatory T cells, and patient outcome in human ovarian carcinoma. Cancer research\| PubMed ID: 17875732	2007
Programmed death-1 concentration at the immunological synapse is determined by ligand affinity and availability. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17968013	2007
Blockade of endogenous B7-H1 suppresses antibacterial protection after primary Listeria monocytogenes infection. Immunology\| PubMed ID: 17971153	2008
Tolerogenic maturation of liver sinusoidal endothelial cells promotes B7-homolog 1-dependent CD8+ T cell tolerance. Hepatology (Baltimore, Md.)\| PubMed ID: 17975811	2008
Multivalent 4-1BB binding aptamers costimulate CD8+ T cells and inhibit tumor growth in mice. The Journal of clinical investigation\| PubMed ID: 18060045	2008
Blocking of monocyte-associated B7-H1 (CD274) enhances HCV-specific T cell immunity in chronic hepatitis C infection. Journal of leukocyte biology\| PubMed ID: 18086898	2008
B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells. Blood\| PubMed ID: 18223165	2008
CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice. Circulation\| PubMed ID: 18285570	2008
B7-H1 restricts neuroantigen-specific T cell responses and confines inflammatory CNS damage: implications for the lesion pathogenesis of multiple sclerosis. European journal of immunology\| PubMed ID: 18421793	2008
Detrimental contribution of the immuno-inhibitor B7-H1 to rabies virus encephalitis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18490751	2008
Inhibitory B7-family molecules in the tumour microenvironment. Nature reviews. Immunology\| PubMed ID: 18500231	2008
Fc-dependent expression of CD137 on human NK cells: insights into "agonistic" effects of anti-CD137 monoclonal antibodies. Blood\| PubMed ID: 18519814	2008
Tumor-induced immune suppression of in vivo effector T-cell priming is mediated by the B7-H1/PD-1 axis and transforming growth factor beta. Cancer research\| PubMed ID: 18593946	2008
B7-H1 on hepatocytes facilitates priming of specific CD8 T cells but limits the specific recall of primed responses. Gastroenterology\| PubMed ID: 18621049	2008
PD-1 ligands expressed on myeloid-derived APC in the CNS regulate T-cell responses in EAE. European journal of immunology\| PubMed ID: 18825752	2008
Cutting edge: IFN-gamma enables APC to promote memory Th17 and abate Th1 cell development. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 18941172	2008
Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infect... Journal of neuroinflammation\| PubMed ID: 18947414	2008
B7-H4-deficient mice display augmented neutrophil-mediated innate immunity. Blood\| PubMed ID: 19109567	2009
Functional B7.2 and B7-H2 molecules on myeloma cells are associated with a growth advantage. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19188146	2009
B7-H1 (PD-L1) on T cells is required for T-cell-mediated conditioning of dendritic cell maturation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19202065	2009
Turning the tide of lymphocyte costimulation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19234146	2009
Palettes of vaccines and immunostimulatory monoclonal antibodies for combination. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19240168	2009
Local expression of B7-H4 by recombinant adenovirus transduction in mouse islets prolongs allograft survival. Transplantation\| PubMed ID: 19307783	2009
PD-1 on dendritic cells impedes innate immunity against bacterial infection. Blood\| PubMed ID: 19339692	2009
Target-dependent B7-H1 regulation contributes to clearance of central nervous system infection and dampens morbidity. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19380790	2009
Fine tuning the immune response through B7-H3 and B7-H4. Immunological reviews\| PubMed ID: 19426220	2009
B and T lymphocyte attenuator tempers early infection immunity. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19587015	2009
Reciprocal differentiation and tissue-specific pathogenesis of Th1, Th2, and Th17 cells in graft-versus-host disease. Blood\| PubMed ID: 19602708	2009
Therapeutic effect of CD137 immunomodulation in lymphoma and its enhancement by Treg depletion. Blood\| PubMed ID: 19641184	2009
Tumor-expressed B7-H1 and B7-DC in relation to PD-1+ T-cell infiltration and survival of patients with cervical carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19825956	2009
Kupffer cell suppression of CD8+ T cells in human hepatocellular carcinoma is mediated by B7-H1/programmed death-1 interactions. Cancer research\| PubMed ID: 19826049	2009
Potential role of decoy B7-H4 in the pathogenesis of rheumatoid arthritis: a mouse model informed by clinical data. PLoS medicine\| PubMed ID: 19841745	2009
NOD2 ligation subverts IFN-alpha production by liver plasmacytoid dendritic cells and inhibits their T cell allostimulatory activity via B7-H1 up-regulation. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19890047	2009
Leucocyte-associated immunoglobulin-like receptor-1 is an inhibitory regulator of contact hypersensitivity. Immunology\| PubMed ID: 19930044	2009
Costimulator B7-DC attenuates strong Th2 responses induced by Nippostrongylus brasiliensis. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20065112	2010
CD137 agonist antibody prevents cancer recurrence: contribution of CD137 on both hematopoietic and nonhematopoietic cells. Blood\| PubMed ID: 20068221	2010
Treatment with anti-CD137 mAbs causes intense accumulations of liver T cells without selective antitumor immunotherapeutic effects in this organ. Cancer immunology, immunotherapy : CII\| PubMed ID: 20336294	2010
PD-1 regulates germinal center B cell survival and the formation and affinity of long-lived plasma cells. Nature immunology\| PubMed ID: 20453843	2010
B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance. Blood\| PubMed ID: 20472828	2010
Interferon-gamma and tumor necrosis factor-alpha induce an immunoinhibitory molecule, B7-H1, via nuclear factor-kappaB activation in blasts in myelodysplastic syndromes. Blood\| PubMed ID: 20472834	2010
Retraction: Naturally occurring human IgM antibody that binds B7-DC and potentiates T cell stimulation by dendritic cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20483792	2010
Deficiency in B7-H1 (PD-L1)/PD-1 coinhibition triggers pancreatic beta-cell destruction by insulin-specific, murine CD8 T-cells. Diabetes\| PubMed ID: 20484136	2010
Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 20516446	2010
Crucial roles of B7-H1 and B7-DC expressed on mesenteric lymph node dendritic cells in the generation of antigen-specific CD4+Foxp3+ regulatory T cells in the establishment of oral tolerance... Blood\| PubMed ID: 20574047	2010
Immunobiology of cancer therapies targeting CD137 and B7-H1/PD-1 cosignal pathways. Current topics in microbiology and immunology\| PubMed ID: 20582531	2011
Structural immunology of costimualtory and coinhibitory molecules. Science China. Life sciences\| PubMed ID: 20596825	2010
B7-H1-dependent sex-related differences in tumor immunity and immunotherapy responses. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 20686128	2010
Retraction: Immunotherapeutic potential of B7-DC (PD-L2) cross-linking antibody in conferring antitumor immunity. Cancer research\| PubMed ID: 21045150	2010
CD137-mediated pathogenesis from chronic hepatitis to hepatocellular carcinoma in hepatitis B virus-transgenic mice. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21059892	2010
B7-H1 expression on non-B and non-T cells promotes distinct effects on T- and B-cell responses in autoimmune arthritis. European journal of immunology\| PubMed ID: 21061440	2010
CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies. Blood\| PubMed ID: 21193697	2011
Host APCs augment in vivo expansion of donor natural regulatory T cells via B7H1/B7.1 in allogeneic recipients. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21263067	2011
Lymphotoxin signal promotes thymic organogenesis by eliciting RANK expression in the embryonic thymic stroma. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21441458	2011
Blockade of B7-H1 (programmed death ligand 1) enhances humoral immunity by positively regulating the generation of T follicular helper cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21490158	2011
Cell surface signaling molecules in the control of immune responses: a tide model. Immunity\| PubMed ID: 21511182	2011
B7-h2 is a costimulatory ligand for CD28 in human. Immunity\| PubMed ID: 21530327	2011
The development and functions of CD4(+) T cells expressing a transgenic TCR specific for an MHC-I-restricted tumor antigenic epitope. Cellular & molecular immunology\| PubMed ID: 21643003	2011
Cutting edge: A monoclonal antibody specific for the programmed death-1 homolog prevents graft-versus-host disease in mouse models. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21768399	2011
Ex vivo expanded hematopoietic stem cells overcome the MHC barrier in allogeneic transplantation. Cell stem cell\| PubMed ID: 21816363	2011
Expression of anti-HVEM single-chain antibody on tumor cells induces tumor-specific immunity with long-term memory. Cancer immunology, immunotherapy : CII\| PubMed ID: 21877247	2012
B7-H4 induces donor-specific tolerance in mouse islet allografts. Cell transplantation\| PubMed ID: 21929869	2012
Early treatment of NOD mice with B7-H4 reduces the incidence of autoimmune diabetes. Diabetes\| PubMed ID: 21984581	2011
B7-H4 Pathway in Islet Transplantation and Î²-Cell Replacement Therapies. Journal of transplantation\| PubMed ID: 22028949	2011
Herpesvirus entry mediator regulates hypoxia-inducible factor-1Î± and erythropoiesis in mice. The Journal of clinical investigation\| PubMed ID: 22080867	2011
Loss of B7-H1 expression by recipient parenchymal cells leads to expansion of infiltrating donor CD8+ T cells and persistence of graft-versus-host disease. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 22156590	2012
Blockade of the B7-H1/PD-1 pathway for cancer immunotherapy. The Yale journal of biology and medicine\| PubMed ID: 22180678	2011
B7-H4 Treatment of T Cells Inhibits ERK, JNK, p38, and AKT Activation. PloS one\| PubMed ID: 22238573	2012
Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer. The Journal of clinical investigation\| PubMed ID: 22326955	2012
The B7 homologues and their receptors in hematologic malignancies. European journal of haematology\| PubMed ID: 22372959	2012
Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells. Cancer research\| PubMed ID: 22427351	2012
Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape. Science translational medicine\| PubMed ID: 22461641	2012
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. The New England journal of medicine\| PubMed ID: 22658127	2012
PD-1 blockage reverses immune dysfunction and hepatitis B viral persistence in a mouse animal model. PloS one\| PubMed ID: 22761734	2012
Blockade of both B7-H4 and CTLA-4 co-signaling pathways enhances mouse islet allograft survival. Islets\| PubMed ID: 22878670	2012
Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells. Blood\| PubMed ID: 22993390	2012
Durable Cancer Regression Off-treatment and Effective Re-induction Therapy with an Anti-PD-1 Antibody. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 23169436	2012
Endogenous Expression of B7-H4 Improves Long-term Murine Islet Allograft Survival. Transplantation\| PubMed ID: 23192157	2013