Colleen Brophy

Department of Surgery, Vanderbilt University Medical Center

Affiliated withVanderbilt University Medical Center

Research Area

Medicine

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title	2024
Publication title Cited by 1	2024

Other Publications

Article	Year
Cell permeant peptide analogues of the small heat shock protein, HSP20, reduce TGF-beta1-induced CTGF expression in keloid fibroblasts. The Journal of investigative dermatology\| PubMed ID: 18787533	2009
The small heat shock protein, HSPB6, in muscle function and disease. Cell stress & chaperones\| PubMed ID: 19568960	2010
Design of a bioactive cell-penetrating peptide: when a transduction domain does more than transduce. Journal of peptide science : an official publication of the European Peptide Society\| PubMed ID: 19691016	2009
A novel cell permeant peptide inhibitor of MAPKAP kinase II inhibits intimal hyperplasia in a human saphenous vein organ culture model. Journal of vascular surgery\| PubMed ID: 20864298	2010
Detrimental effects of mechanical stretch on smooth muscle function in saphenous veins. Journal of vascular surgery\| PubMed ID: 21146345	2011
Surgical skin markers impair human saphenous vein graft smooth muscle and endothelial function. The American surgeon\| PubMed ID: 21944360	2011
Women in academic surgery: the pipeline is busted. Journal of surgical education\| PubMed ID: 22208838	2012
Role of the renin-angiotensin system in the pathogenesis of intimal hyperplasia: therapeutic potential for prevention of vein graft failure? Annals of vascular surgery\| PubMed ID: 22445245	2012
Intimal thickness associated with endothelial dysfunction in human vein grafts. The Journal of surgical research\| PubMed ID: 22763213	2013
Teaching in the operating room: results of a national survey. Journal of surgical education\| PubMed ID: 22910164	2012
Cell-permeant peptide inhibitors of vasospasm and intimal hyperplasia. Vascular\| PubMed ID: 23104826	2013
Role of cyclic nucleotide-dependent actin cytoskeletal dynamics:Ca(2+)](i) and force suppression in forskolin-pretreated porcine coronary arteries. PloS one\| PubMed ID: 23593369	2013
Surgical vein graft preparation promotes cellular dysfunction, oxidative stress, and intimal hyperplasia in human saphenous vein. Journal of vascular surgery\| PubMed ID: 23911244	2014
Pressure control during preparation of saphenous veins. JAMA surgery\| PubMed ID: 24759942	2014
Brilliant blue FCF as an alternative dye for saphenous vein graft marking: effect on conduit function. JAMA surgery\| PubMed ID: 25251505	2014
Brilliant blue FCF is a nontoxic dye for saphenous vein graft marking that abrogates response to injury. Journal of vascular surgery\| PubMed ID: 25704409	2016
Race as a predictor of delay from diagnosis to endarterectomy in clinically significant carotid stenosis. Journal of vascular surgery\| PubMed ID: 25776188	2015
Peripheral venous waveform analysis for detecting early hemorrhage: a pilot study. Intensive care medicine\| PubMed ID: 25862041	2015
Prediction of in-hospital mortality after ruptured abdominal aortic aneurysm repair using an artificial neural network. Journal of vascular surgery\| PubMed ID: 25953014	2015
Preservation solution impacts physiologic function and cellular viability of human saphenous vein graft. Surgery\| PubMed ID: 26003912	2015
Endosomolytic Nano-Polyplex Platform Technology for Cytosolic Peptide Delivery To Inhibit Pathological Vasoconstriction. ACS nano\| PubMed ID: 26004140	2015
MK2 inhibitory peptide delivered in nanopolyplexes prevents vascular graft intimal hyperplasia. Science translational medicine\| PubMed ID: 26062847	2015
An Optimized Preparation Technique for Saphenous Vein Graft. The American surgeon\| PubMed ID: 26140874	2015
Preoperative Predictors of 30-Day Mortality and Prolonged Length of Stay after Above-Knee Amputation. Annals of vascular surgery\| PubMed ID: 26616501	2016
The influence of VKORC1 and CYP2C9 mutations on warfarin response after total hip and knee arthroplasty. Journal of orthopaedics\| PubMed ID: 27047214	2015
Peripheral Venous Waveform Analysis for Detecting Hemorrhage and Iatrogenic Volume Overload in a Porcine Model. Shock (Augusta, Ga.)\| PubMed ID: 27070329	2016
Papaverine Prevents Vasospasm by Regulation of Myosin Light Chain Phosphorylation and Actin Polymerization in Human Saphenous Vein. PloS one\| PubMed ID: 27136356	2016
Aortic arch involvement worsens the prognosis of type B aortic dissections. Journal of vascular surgery\| PubMed ID: 27397897	2016
Hyperlactemia Predicts Surgical Mortality in Patients Presenting With Acute Stanford Type-A Aortic Dissection. Journal of cardiothoracic and vascular anesthesia\| PubMed ID: 27493094	2017
The Case for Endothelial Preservation Pressure-Regulated Distension in the Preparation of Autologous Saphenous Vein Conduits in Cardiac and Peripheral Bypass Operations. Frontiers in surgery\| PubMed ID: 27713879	2016
Use of Brilliant Blue FCF during vein graft preparation inhibits intimal hyperplasia. Journal of vascular surgery\| PubMed ID: 27763268	2016
Mechanism of Enhanced Cellular Uptake and Cytosolic Retention of MK2 Inhibitory Peptide Nano-polyplexes. Cellular and molecular bioengineering\| PubMed ID: 27818713	2016
Calcification of Human Saphenous Vein Associated with Endothelial Dysfunction: A Pilot Histopathophysiological and Demographical Study. Frontiers in surgery\| PubMed ID: 28232909	2017
Unregulated saphenous vein graft distension decreases tissue viscoelasticity. Perfusion\| PubMed ID: 28820033	2017
P2X7R antagonism after subfailure overstretch injury of blood vessels reverses vasomotor dysfunction and prevents apoptosis. Purinergic signalling\| PubMed ID: 28905300	2017
Heparin-functionalized polymer graft surface eluting MK2 inhibitory peptide to improve hemocompatibility and anti-neointimal activity. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 28987880	2017
Limiting Injury During Saphenous Vein Graft Preparation For Coronary Arterial Bypass Prevents Metabolic Decompensation. Scientific reports\| PubMed ID: 29079734	2017
Vascular surgical stretch injury leads to activation of P2X7 receptors and impaired endothelial function. PloS one\| PubMed ID: 29136654	2017
Excipients for the lyoprotection of MAPKAP kinase 2 inhibitory peptide nano-polyplexes. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 29709529	2018
Peripheral Intravenous Volume Analysis (PIVA) for Quantitating Volume Overload in Patients Hospitalized With Acute Decompensated Heart Failure-A Pilot Study. Journal of cardiac failure\| PubMed ID: 29777760	2018
Nanotechnology Enabled Modulation of Signaling Pathways Affects Physiologic Responses in Intact Vascular Tissue. Tissue engineering. Part A\| PubMed ID: 30132374	2019
Corrigendum to "Peripheral IntravenousVolume Analysis (PIVA) for Quantitating Volume Overload in Patients Hospitalized with Acute Decompensated Heart Failure-A Pilot Study" Journal of Cardia... Journal of cardiac failure\| PubMed ID: 31345283	2019
Normal Saline solutions cause endothelial dysfunction through loss of membrane integrity, ATP release, and inflammatory responses mediated by P2X7R/p38 MAPK/MK2 signaling pathways. PloS one\| PubMed ID: 31412063	2019
Observational Study of Noninvasive Venous Waveform Analysis to Assess Intracardiac Filling Pressures During Right Heart Catheterization. Journal of cardiac failure\| PubMed ID: 31574315	2020
An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles. Nature communications\| PubMed ID: 31676764	2019
Non-Invasive Venous waveform Analysis (NIVA) for monitoring blood loss in human blood donors and validation in a porcine hemorrhage model. Journal of clinical anesthesia\| PubMed ID: 31786067	2020
Cell-free hemoglobin increases inflammation, lung apoptosis, and microvascular permeability in murine polymicrobial sepsis. PloS one\| PubMed ID: 32012200	2020
Non-invasive venous waveform analysis (NIVA) for volume assessment in patients undergoing hemodialysis: an observational study. BMC nephrology\| PubMed ID: 32448178	2020
Non-Invasive Venous waveform Analysis (NIVA) for volume assessment during complex cranial vault reconstruction: A proof-of-concept study in children. PloS one\| PubMed ID: 32640004	2020
A brief report on the effects of vasoactive agents on peripheral venous waveforms in a porcine model. JRSM cardiovascular disease\| PubMed ID: 32864123	2020
Physiology and clinical utility of the peripheral venous waveform. JRSM cardiovascular disease\| PubMed ID: 33194174	2020
Hemodynamic Parameters in the Assessment of Fluid Status in a Porcine Hemorrhage and Resuscitation Model. Anesthesiology\| PubMed ID: 33635950	2021
Vasorelaxing cell permeant phosphopeptide mimetics for subarachnoid hemorrhage. European journal of pharmacology\| PubMed ID: 33737008	2021
Noninvasive Venous Waveform Analysis Correlates With Pulmonary Capillary Wedge Pressure and Predicts 30-Day Admission in Patients With Heart Failure Undergoing Right Heart Catheterization. Journal of cardiac failure\| PubMed ID: 34555524	2022
Respiratory Non-Invasive Venous Waveform Analysis for Assessment of Respiratory Distress in Coronavirus Disease 2019 Patients: An Observational Study. Critical care explorations\| PubMed ID: 34617035	2021
Therapeutic MK2 inhibition blocks pathological vascular smooth muscle cell phenotype switch. JCI insight\| PubMed ID: 34622803	2021
Comparison of clinical symptoms and bioimpedance to pulmonary capillary wedge pressure in heart failure. American heart journal plus : cardiology research and practice\| PubMed ID: 35600671	2022
Blocking P2X7 receptor with AZ 10606120 exacerbates vascular hyperpermeability and inflammation in murine polymicrobial sepsis. Physiological reports\| PubMed ID: 35668576	2022
The Effect of Fluid Pre-loading on Vital Signs and Hemodynamic Parameters in a Porcine Model of Lipopolysaccharide-Induced Endotoxemia. Cureus\| PubMed ID: 37692606	2023
The Cell Permeant Phosphopetpide mimetic of VASP Alleviates Motor Function Deficits After Experimental Subarachnoid Hemorrhage. Journal of molecular neuroscience : MN\| PubMed ID: 38214771	2024
Evaluation of common clinical and hemodynamic parameters to pulmonary capillary wedge pressures in patients undergoing right heart catheterization. Medical research archives\| PubMed ID: 38249786	2023