Joseph M. Hyser

Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine

Affiliated withBaylor College of Medicine

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2024

Other Publications

Article	Year
Sequence analysis of the VP4, VP6, VP7, and NSP4 gene products of the bovine rotavirus WC3. Virus genes\| PubMed ID: 12018701	2002
Rotavirus viremia and extraintestinal viral infection in the neonatal rat model. Journal of virology\| PubMed ID: 16641274	2006
Epitope mapping and use of epitope-specific antisera to characterize the VP5* binding site in rotavirus SA11 NSP4. Virology\| PubMed ID: 18164740	2008
Integrins alpha1beta1 and alpha2beta1 are receptors for the rotavirus enterotoxin. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18587047	2008
Rotavirus vaccines and pathogenesis: 2008. Current opinion in gastroenterology\| PubMed ID: 19114772	2009
Rotavirus disrupts calcium homeostasis by NSP4 viroporin activity. mBio\| PubMed ID: 21151776	2010
Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication. Virology\| PubMed ID: 22342275	2012
Genetic divergence of rotavirus nonstructural protein 4 results in distinct serogroup-specific viroporin activity and intracellular punctate structure morphologies. Journal of virology\| PubMed ID: 22357281	2012
Rotavirus non-structural proteins: structure and function. Current opinion in virology\| PubMed ID: 22789743	2012
Autophagy hijacked through viroporin-activated calcium/calmodulin-dependent kinase kinase-β signaling is required for rotavirus replication. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23184977	2012
Activation of the endoplasmic reticulum calcium sensor STIM1 and store-operated calcium entry by rotavirus requires NSP4 viroporin activity. Journal of virology\| PubMed ID: 24109210	2013
A novel form of rotavirus NSP2 and phosphorylation-dependent NSP2-NSP5 interactions are associated with viroplasm assembly. Journal of virology\| PubMed ID: 24198401	2014
Human enteroids: preclinical models of non-inflammatory diarrhea. Stem cell research & therapy\| PubMed ID: 24564938	2013
Human enteroids as an ex-vivo model of host-pathogen interactions in the gastrointestinal tract. Experimental biology and medicine (Maywood, N.J.)\| PubMed ID: 24719375	2014
Structural plasticity of the coiled-coil domain of rotavirus NSP4. Journal of virology\| PubMed ID: 25231315	2014
Use of genetically-encoded calcium indicators for live cell calcium imaging and localization in virus-infected cells. Methods (San Diego, Calif.)\| PubMed ID: 26344758	2015
Pathophysiological Consequences of Calcium-Conducting Viroporins. Annual review of virology\| PubMed ID: 26958925	2015
The Rotavirus NSP4 Viroporin Domain is a Calcium-conducting Ion Channel. Scientific reports\| PubMed ID: 28256607	2017
Human Intestinal Enteroids With Inducible Neurogenin-3 Expression as a Novel Model of Gut Hormone Secretion. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 31029854	2019
Bifidobacterium dentium Fortifies the Intestinal Mucus Layer via Autophagy and Calcium Signaling Pathways. mBio\| PubMed ID: 31213556	2019
Rotavirus Calcium Dysregulation Manifests as Dynamic Calcium Signaling in the Cytoplasm and Endoplasmic Reticulum. Scientific reports\| PubMed ID: 31346185	2019
Recovirus NS1-2 Has Viroporin Activity That Induces Aberrant Cellular Calcium Signaling To Facilitate Virus Replication. mSphere\| PubMed ID: 31533997	2019
Generation of Recombinant Rotavirus Expressing NSP3-UnaG Fusion Protein by a Simplified Reverse Genetics System. Journal of virology\| PubMed ID: 31597761	2019
Discovery of a bacterial peptide as a modulator of GLP-1 and metabolic disease. Scientific reports\| PubMed ID: 32188864	2020
Human intestinal enteroids as a model of -induced enteritis. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 32223302	2020
Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex. Cells\| PubMed ID: 32235678	2020
Rotavirus infection induces glycan availability to promote ileum-specific changes in the microbiome aiding rotavirus virulence. Gut microbes\| PubMed ID: 32404017	2020
Human-Derived Bifidobacterium dentium Modulates the Mammalian Serotonergic System and Gut-Brain Axis. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 32795610	2021
Reuterin disrupts metabolism and pathogenicity through reactive oxygen species generation. Gut microbes\| PubMed ID: 32804011	2020
Enteroaggregative E. coli Adherence to Human Heparan Sulfate Proteoglycans Drives Segment and Host Specific Responses to Infection. PLoS pathogens\| PubMed ID: 32986782	2020
Mucin-Degrading Microbes Release Monosaccharides That Chemoattract and Facilitate Colonization of the Human Intestinal Mucus Layer. ACS infectious diseases\| PubMed ID: 33176423	2021
Rotavirus induces intercellular calcium waves through ADP signaling. Science (New York, N.Y.)\| PubMed ID: 33214249	2020
Bacteroides ovatus Promotes IL-22 Production and Reduces Trinitrobenzene Sulfonic Acid-Driven Colonic Inflammation. The American journal of pathology\| PubMed ID: 33516788	2021
Secretes Outer Membrane Vesicles and Promotes Intestinal Inflammation. mBio\| PubMed ID: 33653893	2021
-derived y-glutamylcysteine suppresses ER-mediated goblet cell stress and reduces TNBS-driven colonic inflammation. Gut microbes\| PubMed ID: 33985416	2021
Gastrointestinal organoids in the study of viral infections. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 36414538	2023
Acute high-fat diet impairs macrophage-supported intestinal damage resolution. JCI insight\| PubMed ID: 36538527	2023
A bioengineered probiotic for the oral delivery of a peptide Kv1.3 channel blocker to treat rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 36595694	2023
Distribution of P2Y and P2X purinergic receptor expression within the intestine. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 37987757	2024
Host IPR channels are dispensable for rotavirus Ca signaling but critical for intercellular Ca waves that prime uninfected cells for rapid virus spread. mBio\| PubMed ID: 38112482	2024