Salvatore Piscuoglio

Visceral Surgery and Precision Medicine Research Laboratory, University of Basel

Affiliated withUniversity of Basel IRCCS Humanitas Research Hospital

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2024

Other Publications

Article	Year
TIA-1 cytotoxic granule-associated RNA binding protein improves the prognostic performance of CD8 in mismatch repair-proficient colorectal cancer. PloS one\| PubMed ID: 21179245	2010
MAGE-A10 is a nuclear protein frequently expressed in high percentages of tumor cells in lung, skin and urothelial malignancies. International journal of cancer\| PubMed ID: 21710496	2011
HMGA1 and HMGA2 protein expression correlates with advanced tumour grade and lymph node metastasis in pancreatic adenocarcinoma. Histopathology\| PubMed ID: 22276603	2012
Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients. Hepatology (Baltimore, Md.)\| PubMed ID: 24114970	2014
3'-UTR poly(T/U) tract deletions and altered expression of EWSR1 are a hallmark of mismatch repair-deficient cancers. Cancer research\| PubMed ID: 24158095	2014
SH2D4A is frequently downregulated in hepatocellular carcinoma and cirrhotic nodules. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 24315626	2014
High-resolution breakpoint analysis provides evidence for the sequence-directed nature of genome rearrangements in hereditary disorders. Human mutation\| PubMed ID: 25418510	2015
HMGA1 overexpression is associated with a particular subset of human breast carcinomas. Journal of clinical pathology\| PubMed ID: 26251519	2016
HMGA1 Expression in Human Hepatocellular Carcinoma Correlates with Poor Prognosis and Promotes Tumor Growth and Migration in in vitro Models. Neoplasia (New York, N.Y.)\| PubMed ID: 27855356	2016
High mobility group A1 enhances tumorigenicity of human cholangiocarcinoma and confers resistance to therapy. Molecular carcinogenesis\| PubMed ID: 28467612	2017
Molecular classification of hepatocellular carcinoma: The view from metabolic zonation. Hepatology (Baltimore, Md.)\| PubMed ID: 28599064	2017
Diverse and Reversion Mutations in Circulating Cell-Free DNA of Therapy-Resistant Breast or Ovarian Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 28765325	2017
NGS-pipe: a flexible, easily extendable and highly configurable framework for NGS analysis. Bioinformatics (Oxford, England)\| PubMed ID: 28968639	2018
Phyllodes tumors with and without fibroadenoma-like areas display distinct genomic features and may evolve through distinct pathways. NPJ breast cancer\| PubMed ID: 29043292	2017
Phosphoprotein enriched in diabetes (PED/PEA15) promotes migration in hepatocellular carcinoma and confers resistance to sorafenib. Cell death & disease\| PubMed ID: 29072691	2017
Genomic and transcriptomic heterogeneity in metaplastic carcinomas of the breast. NPJ breast cancer\| PubMed ID: 29214215	2017
Genomic Analysis Revealed New Oncogenic Signatures in -Mutant Hepatocellular Carcinoma. Frontiers in genetics\| PubMed ID: 29456550	2018
The Role of Long Non-Coding RNAs in Hepatocarcinogenesis. International journal of molecular sciences\| PubMed ID: 29495592	2018
The protein histidine phosphatase LHPP is a tumour suppressor. Nature\| PubMed ID: 29562234	2018
Circulating Cell-Free DNA in Hepatocellular Carcinoma: Current Insights and Outlook. Frontiers in medicine\| PubMed ID: 29632864	2018
Recurrent hotspot mutations in HRAS Q61 and PI3K-AKT pathway genes as drivers of breast adenomyoepitheliomas. Nature communications\| PubMed ID: 29739933	2018
Cancer Diagnosis Using a Liquid Biopsy: Challenges and Expectations. Diagnostics (Basel, Switzerland)\| PubMed ID: 29747380	2018
Genetic heterogeneity and actionable mutations in HER2-positive primary breast cancers and their brain metastases. Oncotarget\| PubMed ID: 29755676	2018
Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies. Cell reports\| PubMed ID: 30067989	2018
Diagnostic Targeted Sequencing Panel for Hepatocellular Carcinoma Genomic Screening. The Journal of molecular diagnostics : JMD\| PubMed ID: 30142445	2018
Lobular Carcinomas Display Intralesion Genetic Heterogeneity and Clonal Evolution in the Progression to Invasive Lobular Carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 30185420	2019
Reliability of Whole-Exome Sequencing for Assessing Intratumor Genetic Heterogeneity. Cell reports\| PubMed ID: 30404001	2018
Fibroepithelial Breast Lesion: When Sequencing Can Help to Make a Clinical Decision. A Case Report. Clinical breast cancer\| PubMed ID: 30470624	2019
Therapeutic Targeting of CD146/MCAM Reduces Bone Metastasis in Prostate Cancer. Molecular cancer research : MCR\| PubMed ID: 30745464	2019
Convergent Evolution of Copy Number Alterations in Multi-Centric Hepatocellular Carcinoma. Scientific reports\| PubMed ID: 30872650	2019
Genomic characterization of metastatic breast cancers. Nature\| PubMed ID: 31118521	2019
PipeIT: A Singularity Container for Molecular Diagnostic Somatic Variant Calling on the Ion Torrent Next-Generation Sequencing Platform. The Journal of molecular diagnostics : JMD\| PubMed ID: 31229654	2019
Infiltration by myeloperoxidase-positive neutrophils is an independent prognostic factor in breast cancer. Breast cancer research and treatment\| PubMed ID: 31267330	2019
Author Correction: Genomic characterization of metastatic breast cancers. Nature\| PubMed ID: 31308536	2019
Hepatocellular Carcinoma Xenografts Established From Needle Biopsies Preserve the Characteristics of the Originating Tumors. Hepatology communications\| PubMed ID: 31334445	2019
Nectin-4 Expression Is an Independent Prognostic Biomarker and Associated With Better Survival in Triple-Negative Breast Cancer. Frontiers in medicine\| PubMed ID: 31572728	2019
Preoperative plasma fatty acid metabolites inform risk of prostate cancer progression and may be used for personalized patient stratification. BMC cancer\| PubMed ID: 31842810	2019
LATS1 but not LATS2 represses autophagy by a kinase-independent scaffold function. Nature communications\| PubMed ID: 31848340	2019
Hormone receptor and HER2 assessment in breast carcinoma metastatic to bone: A comparison between FNA cell blocks and decalcified core needle biopsies. Cancer cytopathology\| PubMed ID: 31883437	2020
Corrigendum to "HMGA1 expression in human hepatocellular carcinoma correlates with poor prognosis and promotes tumor growth and migration in in vitro models" [Neoplasia 18 (2016) 724-731]. Neoplasia (New York, N.Y.)\| PubMed ID: 32438307	2020
A Pygopus 2-Histone Interaction Is Critical for Cancer Cell Dedifferentiation and Progression in Malignant Breast Cancer. Cancer research\| PubMed ID: 32586983	2020
Reliability of liquid biopsy analysis: an inter-laboratory comparison of circulating tumor DNA extraction and sequencing with different platforms. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 32616816	2020
Identification of Somatic Mutations in Thirty-year-old Serum Cell-free DNA From Patients With Breast Cancer: A Feasibility Study. Clinical breast cancer\| PubMed ID: 32650988	2020
High Expression of FAP in Colorectal Cancer Is Associated With Angiogenesis and Immunoregulation Processes. Frontiers in oncology\| PubMed ID: 32733792	2020
Prevention of dsRNA-induced interferon signaling by AGO1x is linked to breast cancer cell proliferation. The EMBO journal\| PubMed ID: 32812257	2020
Infiltration by IL22-Producing T Cells Promotes Neutrophil Recruitment and Predicts Favorable Clinical Outcome in Human Colorectal Cancer. Cancer immunology research\| PubMed ID: 32839156	2020
The genetic landscape of metaplastic breast cancers and uterine carcinosarcomas. Molecular oncology\| PubMed ID: 33021035	2021
Deciphering the clonal relationship between glandular and squamous components in adenosquamous carcinoma of the lung using whole exome sequencing. Lung cancer (Amsterdam, Netherlands)\| PubMed ID: 33137577	2020
Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity. Nature communications\| PubMed ID: 33144576	2020
Prognostic significance of CD8+ T-cells density in stage III colorectal cancer depends on SDF-1 expression. Scientific reports\| PubMed ID: 33436863	2021
Patient-derived xenografts and organoids model therapy response in prostate cancer. Nature communications\| PubMed ID: 33602919	2021
Nestin and CD34 expression in colorectal cancer predicts improved overall survival. Acta oncologica (Stockholm, Sweden)\| PubMed ID: 33734917	2021
Adenylosuccinate lyase is oncogenic in colorectal cancer by causing mitochondrial dysfunction and independent activation of NRF2 and mTOR-MYC-axis. Theranostics\| PubMed ID: 33754045	2021
Genomic characterization of small cell carcinomas of the uterine cervix. Molecular oncology\| PubMed ID: 33830625	2022
Transcriptional Enhancer Factor Domain Family member 4 Exerts an Oncogenic Role in Hepatocellular Carcinoma by Hippo-Independent Regulation of Heat Shock Protein 70 Family Members. Hepatology communications\| PubMed ID: 33860124	2021
Non-viral gene delivery of the oncotoxic protein NS1 for treatment of hepatocellular carcinoma. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 33894304	2021
Prostate cancer patient-derived organoids: detailed outcome from a prospective cohort of 81 clinical specimens. The Journal of pathology\| PubMed ID: 33934365	2021
Genomic evolutionary trajectory of metastatic squamous cell carcinoma of the lung. Translational lung cancer research\| PubMed ID: 34012793	2021
Mapping of mA and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-Low Induction of Therapy Resistance. Molecular cancer research : MCR\| PubMed ID: 34088870	2021
ZNRF3 and RNF43 cooperate to safeguard metabolic liver zonation and hepatocyte proliferation. Cell stem cell\| PubMed ID: 34129813	2021
USP29-mediated HIF1α stabilization is associated with Sorafenib resistance of hepatocellular carcinoma cells by upregulating glycolysis. Oncogenesis\| PubMed ID: 34272356	2021
Systematic identification of novel cancer genes through analysis of deep shRNA perturbation screens. Nucleic acids research\| PubMed ID: 34313788	2021
mTOR signaling mediates ILC3-driven immunopathology. Mucosal immunology\| PubMed ID: 34341503	2021
Multi-omics data integration reveals novel drug targets in hepatocellular carcinoma. BMC genomics\| PubMed ID: 34348664	2021
YAP/TAZ and ATF4 drive resistance to Sorafenib in hepatocellular carcinoma by preventing ferroptosis. EMBO molecular medicine\| PubMed ID: 34664408	2021
High Density of CD16+ Tumor-Infiltrating Immune Cells in Recurrent Ovarian Cancer Is Associated with Enhanced Responsiveness to Chemotherapy and Prolonged Overall Survival. Cancers\| PubMed ID: 34830938	2021
Epigenetic priming in chronic liver disease impacts the transcriptional and genetic landscapes of hepatocellular carcinoma. Molecular oncology\| PubMed ID: 34863035	2022
Standardizing Patient-Derived Organoid Generation Workflow to Avoid Microbial Contamination From Colorectal Cancer Tissues. Frontiers in oncology\| PubMed ID: 35083141	2021
miR-579-3p Controls Hepatocellular Carcinoma Formation by Regulating the Phosphoinositide 3-Kinase-Protein Kinase B Pathway in Chronically Inflamed Liver. Hepatology communications\| PubMed ID: 35132819	2022
Circulating Cell-Free DNA Captures the Intratumor Heterogeneity in Multinodular Hepatocellular Carcinoma. JCO precision oncology\| PubMed ID: 35263170	2022
Skeletal Muscle Disorders: A Noncardiac Source of Cardiac Troponin T. Circulation\| PubMed ID: 35389756	2022
GATA3 and MDM2 are synthetic lethal in estrogen receptor-positive breast cancers. Communications biology\| PubMed ID: 35440675	2022
Alterations in homologous recombination repair genes in prostate cancer brain metastases. Nature communications\| PubMed ID: 35504881	2022
Integrative proteogenomic characterization of hepatocellular carcinoma across etiologies and stages. Nature communications\| PubMed ID: 35508466	2022
Genomic analysis of focal nodular hyperplasia with associated hepatocellular carcinoma unveils its malignant potential: a case report. Communications medicine\| PubMed ID: 35603298	2022
Author Correction: GATA3 and MDM2 are synthetic lethal in estrogen receptor-positive breast cancers. Communications biology\| PubMed ID: 35787660	2022
Patient-derived tumor organoids for personalized medicine in a patient with rare hepatocellular carcinoma with neuroendocrine differentiation: a case report. Communications medicine\| PubMed ID: 35789568	2022
The Potential Tumor-Suppressor DHRS7 Inversely Correlates with EGFR Expression in Prostate Cancer Cells and Tumor Samples. Cancers\| PubMed ID: 35804847	2022
The Role of Chronic Liver Diseases in the Emergence and Recurrence of Hepatocellular Carcinoma: An Omics Perspective. Frontiers in medicine\| PubMed ID: 35814741	2022
Transposon-activated POU5F1B promotes colorectal cancer growth and metastasis. Nature communications\| PubMed ID: 35987910	2022
Response by du Fay de Lavallaz et al to Letter Regarding Article, "Skeletal Muscle Disorders: A Noncardiac Source of Cardiac Troponin T". Circulation\| PubMed ID: 36214135	2022
Live slow-frozen human tumor tissues viable for 2D, 3D, ex vivo cultures and single-cell RNAseq. Communications biology\| PubMed ID: 36307545	2022
The prognostic significance of CXCR4 and SDF-1 in differentiated thyroid cancer depends on CD8+ density. BMC endocrine disorders\| PubMed ID: 36419107	2022
Discovery of synthetic lethal interactions from large-scale pan-cancer perturbation screens. Nature communications\| PubMed ID: 36517508	2022
PI5P4Kα supports prostate cancer metabolism and exposes a survival vulnerability during androgen receptor inhibition. Science advances\| PubMed ID: 36724278	2023
DNA Methylation Landscapes of Prostate Cancer Brain Metastasis Are Shaped by Early Driver Genetic Alterations. Cancer research\| PubMed ID: 36749655	2023
PipeIT2: A tumor-only somatic variant calling workflow for molecular diagnostic Ion Torrent sequencing data. Genomics\| PubMed ID: 36796655	2023
PI3K inhibition circumvents resistance to SHP2 blockade in metastatic triple-negative breast cancer. Journal of mammary gland biology and neoplasia\| PubMed ID: 37294349	2023
Minor intron splicing is critical for survival of lethal prostate cancer. Molecular cell\| PubMed ID: 37295433	2023
Cylindroma of the breast with CYLD gene mutation: a case report and review of the literature. Molecular biology reports\| PubMed ID: 37389703	2023
Early Age of Onset Is an Independent Predictor for a Worse Response to Neoadjuvant Therapies in Sporadic Rectal Cancer Patients. Cancers\| PubMed ID: 37509411	2023
Colitis Is Associated with Loss of the Histidine Phosphatase LHPP and Upregulation of Histidine Phosphorylation in Intestinal Epithelial Cells. Biomedicines\| PubMed ID: 37626656	2023
Arginine reprograms metabolism in liver cancer via RBM39. Cell\| PubMed ID: 37804830	2023
Patient-derived organoids identify tailored therapeutic options and determinants of plasticity in sarcomatoid urothelial bladder cancer. NPJ precision oncology\| PubMed ID: 37919480	2023
High density of CXCL12-positive immune cell infiltration predicts chemosensitivity and recurrence-free survival in ovarian carcinoma. Journal of cancer research and clinical oncology\| PubMed ID: 37966614	2023
Fragment-sequencing unveils local tissue microenvironments at single-cell resolution. Nature communications\| PubMed ID: 38012149	2023
Analysis of off-tumour toxicities of T-cell-engaging bispecific antibodies via donor-matched intestinal organoids and tumouroids. Nature biomedical engineering\| PubMed ID: 38114742	2023
Cell-Free DNA Genomic Profiling and Its Clinical Implementation in Advanced Prostate Cancer. Cancers\| PubMed ID: 38201475	2023