Carina Mallard

Centre of Perinatal Medicine and Health, University of Gothenburg

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2024

Other Publications

Article	Year
Single-cell atlas reveals meningeal leukocyte heterogeneity in the developing mouse brain. Genes & development\| PubMed ID: 34301765	2021
Function and Biomarkers of the Blood-Brain Barrier in a Neonatal Germinal Matrix Haemorrhage Model. Cells\| PubMed ID: 34359845	2021
ECG and heart rate variability changes in preterm and near-term fetal lamb following LPS exposure. Reproductive sciences (Thousand Oaks, Calif.)\| PubMed ID: 18456675	2008
Developmental shift of cyclophilin D contribution to hypoxic-ischemic brain injury. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 19244535	2009
White matter damage after chronic subclinical inflammation in newborn mice. Journal of child neurology\| PubMed ID: 19745089	2009
Lipopolysaccharide sensitizes neonatal hypoxic-ischemic brain injury in a MyD88-dependent manner. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19917690	2009
The role of Toll-like receptors in perinatal brain injury. Clinics in perinatology\| PubMed ID: 19944834	2009
Galectin-3 contributes to neonatal hypoxic-ischemic brain injury. Neurobiology of disease\| PubMed ID: 20053377	2010
Attenuation of reactive gliosis does not affect infarct volume in neonatal hypoxic-ischemic brain injury in mice. PloS one\| PubMed ID: 20442854	2010
Neuroprotective effect of Bax-inhibiting peptide on neonatal brain injury. Stroke; a journal of cerebral circulation\| PubMed ID: 20671246	2010
The Nrf2-inducible antioxidant defense in astrocytes can be both up- and down-regulated by activated microglia:Involvement of p38 MAPK. Glia\| PubMed ID: 21351160	2011
Learning and activity after irradiation of the young mouse brain analyzed in adulthood using unbiased monitoring in a home cage environment. Radiation research\| PubMed ID: 21388277	2011
Regulation of toll-like receptor 1 and -2 in neonatal mice brains after hypoxia-ischemia. Journal of neuroinflammation\| PubMed ID: 21569241	2011
Systemic stimulation of TLR2 impairs neonatal mouse brain development. PloS one\| PubMed ID: 21573120	2011
Safety aspects of longitudinal administration of IGF-I/IGFBP-3 complex in neonatal mice. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society\| PubMed ID: 21696987	2011
Activated microglia decrease histone acetylation and Nrf2-inducible anti-oxidant defence in astrocytes: restoring effects of inhibitors of HDACs, p38 MAPK and GSK3β. Neurobiology of disease\| PubMed ID: 21757005	2011
Trace fear conditioning detects hypoxic-ischemic brain injury in neonatal mice. Developmental neuroscience\| PubMed ID: 21778703	2011
Delayed cortical impairment following lipopolysaccharide exposure in preterm fetal sheep. Annals of neurology\| PubMed ID: 22002627	2011
Infection-induced vulnerability of perinatal brain injury. Neurology research international\| PubMed ID: 22135745	2012
Inflammatory-induced hibernation in the fetus: priming of fetal sheep metabolism correlates with developmental brain injury. PloS one\| PubMed ID: 22242129	2011
Combined effect of hypothermia and caspase-2 gene deficiency on neonatal hypoxic-ischemic brain injury. Pediatric research\| PubMed ID: 22322383	2012
Which neuroprotective agents are ready for bench to bedside translation in the newborn infant? The Journal of pediatrics\| PubMed ID: 22325255	2012
Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury. Journal of neuroinflammation\| PubMed ID: 22512781	2012
From mice to women and back again: causalities and clues for Chlamydia-induced tubal ectopic pregnancy. Fertility and sterility\| PubMed ID: 22884019	2012
Dual TNFα-induced effects on NRF2 mediated antioxidant defence in astrocyte-rich cultures: role of protein kinase activation. Neurochemical research\| PubMed ID: 22941452	2012
Pathological changes in the white matter after spinal contusion injury in the rat. PloS one\| PubMed ID: 22952690	2012
A neonatal model of intravenous Staphylococcus epidermidis infection in mice <24 h old enables characterization of early innate immune responses. PloS one\| PubMed ID: 22970147	2012
Innate immune regulation by toll-like receptors in the brain. ISRN neurology\| PubMed ID: 23097717	2012
Expression of the Nrf2-system at the blood-CSF barrier is modulated by neonatal inflammation and hypoxia-ischemia. Journal of inherited metabolic disease\| PubMed ID: 23109062	2013
Interaction of inflammation and hyperoxia in a rat model of neonatal white matter damage. PloS one\| PubMed ID: 23155446	2012
Radixin expression in microglia after cortical stroke lesion. Glia\| PubMed ID: 23440885	2013
Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro. Brain, behavior, and immunity\| PubMed ID: 23454862	2013
Time-dependent effects of systemic lipopolysaccharide injection on regulators of antioxidant defence Nrf2 and PGC-1α in the neonatal rat brain. Neuroimmunomodulation\| PubMed ID: 23635713	2013
Receptor for complement peptide C3a: a therapeutic target for neonatal hypoxic-ischemic brain injury. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 23737250	2013
Regulation of Toll-like receptors in the choroid plexus in the immature brain after systemic inflammatory stimuli. Translational stroke research\| PubMed ID: 23741282	2013
Preface. Developmental neuroscience\| PubMed ID: 23796853	2013
Toll-like receptor-3 activation increases the vulnerability of the neonatal brain to hypoxia-ischemia. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 23864690	2013
Death associated protein kinases: molecular structure and brain injury. International journal of molecular sciences\| PubMed ID: 23880846	2013
NRF2-regulation in brain health and disease: implication of cerebral inflammation. Neuropharmacology\| PubMed ID: 24262633	2014
Astrocytes and microglia in acute cerebral injury underlying cerebral palsy associated with preterm birth. Pediatric research\| PubMed ID: 24336433	2014
Innate defense regulator peptide 1018 protects against perinatal brain injury. Annals of neurology\| PubMed ID: 24339166	2014
Perinatal hypoxia-ischemia reduces α 7 nicotinic receptor expression and selective α 7 nicotinic receptor stimulation suppresses inflammation and promotes microglial Mox phenotype. BioMed research international\| PubMed ID: 24757672	2014
Microglia toxicity in preterm brain injury. Reproductive toxicology (Elmsford, N.Y.)\| PubMed ID: 24768662	2014
Infection-induced inflammation and cerebral injury in preterm infants. The Lancet. Infectious diseases\| PubMed ID: 24877996	2014
Exendin-4 reduces ischemic brain injury in normal and aged type 2 diabetic mice and promotes microglial M2 polarization. PloS one\| PubMed ID: 25101679	2014
The immune response after hypoxia-ischemia in a mouse model of preterm brain injury. Journal of neuroinflammation\| PubMed ID: 25187205	2014
The effect of osteopontin and osteopontin-derived peptides on preterm brain injury. Journal of neuroinflammation\| PubMed ID: 25465048	2014
Brain barrier properties and cerebral blood flow in neonatal mice exposed to cerebral hypoxia-ischemia. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 25627141	2015
The role of inflammation in perinatal brain injury. Nature reviews. Neurology\| PubMed ID: 25686754	2015
Potential neuroprotective strategies for perinatal infection and inflammation. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience\| PubMed ID: 25702527	2015
Transcriptomal changes and functional annotation of the developing non-human primate choroid plexus. Frontiers in neuroscience\| PubMed ID: 25814924	2015
Does Caspase-6 Have a Role in Perinatal Brain Injury? Developmental neuroscience\| PubMed ID: 25823427	2015
Staphylococcus epidermidis Bacteremia Induces Brain Injury in Neonatal Mice via Toll-like Receptor 2-Dependent and -Independent Pathways. The Journal of infectious diseases\| PubMed ID: 25883383	2015
Expression of tight junction proteins and transporters for xenobiotic metabolism at the blood-CSF barrier during development in the nonhuman primate (P. hamadryas). Reproductive toxicology (Elmsford, N.Y.)\| PubMed ID: 26092209	2015
Modeling Ischemia in the Immature Brain: How Translational Are Animal Models? Stroke\| PubMed ID: 26272384	2015
GSK3β inhibition protects the immature brain from hypoxic-ischaemic insult via reduced STAT3 signalling. Neuropharmacology\| PubMed ID: 26384655	2016
New means to assess neonatal inflammatory brain injury. Journal of neuroinflammation\| PubMed ID: 26407958	2015
The consequences of fetal growth restriction on brain structure and neurodevelopmental outcome. The Journal of physiology\| PubMed ID: 26607046	2016
Editorial: White blood cells matter in neonatal white-matter injury. Journal of leukocyte biology\| PubMed ID: 26733001	2016
Cerebrospinal fluid levels of insulin, leptin, and agouti-related protein in relation to BMI in pregnant women. Obesity (Silver Spring, Md.)\| PubMed ID: 27130070	2016
TLR2-mediated leukocyte trafficking to the developing brain. Journal of leukocyte biology\| PubMed ID: 27493242	2017
Spirulina diet to lactating mothers protects the antioxidant system and reduces inflammation in post-natal brain after systemic inflammation. Nutritional neuroscience\| PubMed ID: 27571388	2018
Neonatal microglia: The cornerstone of brain fate. Brain, behavior, and immunity\| PubMed ID: 27596692	2017
Diabetes negatively affects cortical and striatal GABAergic neurons: an effect that is partially counteracted by exendin-4. Bioscience reports\| PubMed ID: 27780892	2016
Immune responses in perinatal brain injury. Brain, behavior, and immunity\| PubMed ID: 27865947	2017
Sustained Effects of Neonatal Systemic Lipopolysaccharide on IL-1β and Nrf2 in Adult Rat Substantia Nigra Are Partly Normalized by a Spirulina-Enriched Diet. Neuroimmunomodulation\| PubMed ID: 27931028	2016
Temporal Characterization of Microglia/Macrophage Phenotypes in a Mouse Model of Neonatal Hypoxic-Ischemic Brain Injury. Frontiers in cellular neuroscience\| PubMed ID: 28018179	2016
Intranasal C3a treatment ameliorates cognitive impairment in a mouse model of neonatal hypoxic-ischemic brain injury. Experimental neurology\| PubMed ID: 28062175	2017
Effect of Trp53 gene deficiency on brain injury after neonatal hypoxia-ischemia. Oncotarget\| PubMed ID: 28076846	2017
Systemic activation of Toll-like receptor 2 suppresses mitochondrial respiration and exacerbates hypoxic-ischemic injury in the developing brain. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 28139935	2017
Elevated levels of circulating cell-free DNA and neutrophil proteins are associated with neonatal sepsis and necrotizing enterocolitis in immature mice, pigs and infants. Innate immunity\| PubMed ID: 28714327	2017
Effect of Neuroinflammation on Synaptic Organization and Function in the Developing Brain: Implications for Neurodevelopmental and Neurodegenerative Disorders. Frontiers in cellular neuroscience\| PubMed ID: 28744200	2017
Mitochondria, Bioenergetics and Excitotoxicity: New Therapeutic Targets in Perinatal Brain Injury. Frontiers in cellular neuroscience\| PubMed ID: 28747873	2017
Translational Stroke Research: Vision and Opportunities. Stroke\| PubMed ID: 28751554	2017
Cell Death in the Developing Brain after Hypoxia-Ischemia. Frontiers in cellular neuroscience\| PubMed ID: 28878624	2017
Central and Peripheral Leptin and Agouti-Related Protein during and after Pregnancy in Relation to Weight Change. Clinical endocrinology\| PubMed ID: 29154467	2017
γδ T Cells Contribute to Injury in the Developing Brain. The American journal of pathology\| PubMed ID: 29248460	2018
γδT cells but not αβT cells contribute to sepsis-induced white matter injury and motor abnormalities in mice. Journal of neuroinflammation\| PubMed ID: 29262837	2017
Mitochondrial dynamics, mitophagy and biogenesis in neonatal hypoxic-ischaemic brain injury. FEBS letters\| PubMed ID: 29265370	2018
Microglia and Neonatal Brain Injury. Neuroscience\| PubMed ID: 29352997	2019
The myth of the immature barrier systems in the developing brain: role in perinatal brain injury. The Journal of physiology\| PubMed ID: 29528501	2018
Lymphocytes Contribute to the Pathophysiology of Neonatal Brain Injury. Frontiers in neurology\| PubMed ID: 29615958	2018
Myelination induction by a histamine H3 receptor antagonist in a mouse model of preterm white matter injury. Brain, behavior, and immunity\| PubMed ID: 30218783	2018
Peripheral myeloid cells contribute to brain injury in male neonatal mice. Journal of neuroinflammation\| PubMed ID: 30376851	2018
Lack of the brain-specific isoform of apoptosis-inducing factor aggravates cerebral damage in a model of neonatal hypoxia-ischemia. Cell death & disease\| PubMed ID: 30584234	2018
A novel image segmentation method for the evaluation of inflammation-induced cortical and hippocampal white matter injury in neonatal mice. Journal of chemical neuroanatomy\| PubMed ID: 30586607	2019
Lipopolysaccharide-induced alteration of mitochondrial morphology induces a metabolic shift in microglia modulating the inflammatory response in vitro and in vivo. Glia\| PubMed ID: 30637805	2019
Bestrophin-3 Expression in a Subpopulation of Astrocytes in the Neonatal Brain After Hypoxic-Ischemic Injury. Frontiers in physiology\| PubMed ID: 30761013	2019
Choroid plexus transcriptome and ultrastructure analysis reveals a TLR2-specific chemotaxis signature and cytoskeleton remodeling in leukocyte trafficking. Brain, behavior, and immunity\| PubMed ID: 30822467	2019
The Role of Mitochondrial and Endoplasmic Reticulum Reactive Oxygen Species Production in Models of Perinatal Brain Injury. Antioxidants & redox signaling\| PubMed ID: 30957515	2019
Genetic or Other Causation Should Not Change the Clinical Diagnosis of Cerebral Palsy. Journal of child neurology\| PubMed ID: 30963790	2019
Evidence for Sexual Dimorphism in the Response to TLR3 Activation in the Developing Neonatal Mouse Brain: A Pilot Study. Frontiers in physiology\| PubMed ID: 30971945	2019
Sex-Dependent Effects of Perinatal Inflammation on the Brain: Implication for Neuro-Psychiatric Disorders. International journal of molecular sciences\| PubMed ID: 31071949	2019
Dysmaturation of Somatostatin Interneurons Following Umbilical Cord Occlusion in Preterm Fetal Sheep. Frontiers in physiology\| PubMed ID: 31178744	2019
Positive and negative conditioning in the neonatal brain. Conditioning medicine\| PubMed ID: 31214666	2018
Longitudinal changes in adipokines and free leptin index during and after pregnancy in women with obesity. International journal of obesity (2005)\| PubMed ID: 31551485	2020
Microbial invasion of the amniotic cavity is associated with impaired cognitive and motor function at school age in preterm children. Pediatric research\| PubMed ID: 31711067	2020
Vancomycin Is Protective in a Neonatal Mouse Model of -Potentiated Hypoxic-Ischemic Brain Injury. Antimicrobial agents and chemotherapy\| PubMed ID: 31818825	2020
N-acetylcysteine inhibits bacterial lipopeptide-mediated neutrophil transmigration through the choroid plexus in the developing brain. Acta neuropathologica communications\| PubMed ID: 31973769	2020
Overexpression of apoptosis inducing factor aggravates hypoxic-ischemic brain injury in neonatal mice. Cell death & disease\| PubMed ID: 32001673	2020
Flinders sensitive line rats are resistant to infarction following transient occlusion of the middle cerebral artery. Brain research\| PubMed ID: 32194078	2020
Inhibiting the interaction between apoptosis-inducing factor and cyclophilin A prevents brain injury in neonatal mice after hypoxia-ischemia. Neuropharmacology\| PubMed ID: 32277944	2020
Sensitizes Perinatal Hypoxic-Ischemic Brain Injury in Male but Not Female Mice. Frontiers in immunology\| PubMed ID: 32373108	2020
A Systematic Review of Magnesium Sulfate for Perinatal Neuroprotection: What Have We Learnt From the Past Decade? Frontiers in neurology\| PubMed ID: 32536903	2020
Expression of S100A Alarmins in Cord Blood Monocytes Is Highly Associated With Chorioamnionitis and Fetal Inflammation in Preterm Infants. Frontiers in immunology\| PubMed ID: 32612607	2020
Type 2 Innate Lymphoid Cells Accumulate in the Brain After Hypoxia-Ischemia but Do Not Contribute to the Development of Preterm Brain Injury. Frontiers in cellular neuroscience\| PubMed ID: 32848629	2020
Infant body composition relationship to maternal adipokines and fat mass: the PONCH study. Pediatric research\| PubMed ID: 32927470	2021
Association between inflammatory response and outcome after subarachnoid haemorrhage. Acta neurologica Scandinavica\| PubMed ID: 32990943	2021
Neuroprotection offered by mesenchymal stem cells in perinatal brain injury: Role of mitochondria, inflammation, and reactive oxygen species. Journal of neurochemistry\| PubMed ID: 33314066	2021
Dual Profile of Environmental Enrichment and Autistic-Like Behaviors in the Maternal Separated Model in Rats. International journal of molecular sciences\| PubMed ID: 33503967	2021
Growth-differentiation-factor 15 levels in obese and healthy pregnancies: Relation to insulin resistance and insulin secretory function. Clinical endocrinology\| PubMed ID: 33547817	2021
Circulating tight-junction proteins are potential biomarkers for blood-brain barrier function in a model of neonatal hypoxic/ischemic brain injury. Fluids and barriers of the CNS\| PubMed ID: 33568200	2021
The selective alpha7 nicotinic acetylcholine receptor agonist AR-R17779 does not affect ischemia-reperfusion brain injury in mice. Bioscience reports\| PubMed ID: 34008839	2021
Growth differentiation factor 15 increases in both cerebrospinal fluid and serum during pregnancy. PloS one\| PubMed ID: 34043633	2021
Galectin-3 Modulates Microglia Inflammation in vitro but Not Neonatal Brain Injury in vivo under Inflammatory Conditions. Developmental neuroscience\| PubMed ID: 34130282	2021
Viral mimetic triggers cerebral arteriopathy in juvenile brain via neutrophil elastase and NETosis. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 34293939	2021
Microglia activation in postmortem brains with schizophrenia demonstrates distinct morphological changes between brain regions. Brain pathology (Zurich, Switzerland)\| PubMed ID: 34297453	2022
Administration of cyclic glycine-proline during infancy improves adult spatial memory, astrocyte plasticity, vascularization and GluR-1 expression in rats. Nutritional neuroscience\| PubMed ID: 34565308	2022
White matter injury but not germinal matrix hemorrhage induces elevated osteopontin expression in human preterm brains. Acta neuropathologica communications\| PubMed ID: 34654477	2021
Maternal n-3 Polyunsaturated Fatty Acid Enriched Diet Commands Fatty Acid Composition in Postnatal Brain and Protects from Neonatal Arterial Focal Stroke. Translational stroke research\| PubMed ID: 34674145	2022
N-Acetyl Cysteine Restores Sirtuin-6 and Decreases HMGB1 Release Following Lipopolysaccharide-Sensitized Hypoxic-Ischemic Brain Injury in Neonatal Mice. Frontiers in cellular neuroscience\| PubMed ID: 34867200	2021
C3a Receptor Signaling Inhibits Neurodegeneration Induced by Neonatal Hypoxic-Ischemic Brain Injury. Frontiers in immunology\| PubMed ID: 34975856	2021
Scavenger receptor CD36 governs recruitment of myeloid cells to the blood-CSF barrier after stroke in neonatal mice. Journal of neuroinflammation\| PubMed ID: 35148760	2022
Induction of Mitochondrial Fragmentation and Mitophagy after Neonatal Hypoxia-Ischemia. Cells\| PubMed ID: 35406757	2022
An Optimized and Detailed Step-by-Step Protocol for the Analysis of Neuronal Morphology in Golgi-Stained Fetal Sheep Brain. Developmental neuroscience\| PubMed ID: 35447627	2022
Reelin cells and sex-dependent synaptopathology in autism following postnatal immune activation. British journal of pharmacology\| PubMed ID: 35474185	2022
Sex-Dependent Gliovascular Interface Abnormality in the Hippocampus following Postnatal Immune Activation in Mice. Developmental neuroscience\| PubMed ID: 35705008	2022
Geometrical modelling of neuronal clustering and development. Heliyon\| PubMed ID: 35847609	2022
The Alpha 7 Nicotinic Acetylcholine Receptor Does Not Affect Neonatal Brain Injury. Biomedicines\| PubMed ID: 36009570	2022
Transcriptome network analysis links perinatal Staphylococcus epidermidis infection to microglia reprogramming in the immature hippocampus. Glia\| PubMed ID: 37246946	2023
Proteomics identifies lipocalin-2 in neonatal inflammation associated with cerebrovascular alteration in mice and preterm infants. iScience\| PubMed ID: 37496672	2023
Two different isoforms of osteopontin modulate myelination and axonal integrity. FASEB bioAdvances\| PubMed ID: 37554545	2023
Therapeutic Effect of Nicotinamide Mononucleotide for Hypoxic-Ischemic Brain Injury in Neonatal Mice. ASN neuro\| PubMed ID: 37787108	2023
Immune-Neurovascular Interactions in Experimental Perinatal and Childhood Arterial Ischemic Stroke. Stroke\| PubMed ID: 38252757	2024
Long-term impact of maternal obesity on the gliovascular unit and ephrin signaling in the hippocampus of adult offspring. Journal of neuroinflammation\| PubMed ID: 38308309	2024
From hormones to behavior through microglial mitochondrial function. Brain, behavior, and immunity\| PubMed ID: 38341051	2024