Christopher S. Thom

Division of Neonatology, Children’s Hospital of Philadelphia

Affiliated withChildren’s Hospital of Philadelphia University of Pennsylvania Perelman School of Medicine

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2024

Other Publications

Article	Year
Loss of the epigenetic tumor suppressor SNF5 leads to cancer without genomic instability. Molecular and cellular biology\| PubMed ID: 18710953	2008
Integrated protein quality-control pathways regulate free α-globin in murine β-thalassemia. Blood\| PubMed ID: 22427201	2012
Hemoglobin variants: biochemical properties and clinical correlates. Cold Spring Harbor perspectives in medicine\| PubMed ID: 23388674	2013
Trim58 degrades Dynein and regulates terminal erythropoiesis. Developmental cell\| PubMed ID: 25241935	2014
FLI1 level during megakaryopoiesis affects thrombopoiesis and platelet biology. Blood\| PubMed ID: 28432223	2017
Utility and limitations of exome sequencing in the molecular diagnosis of pediatric inherited platelet disorders. American journal of hematology\| PubMed ID: 28960434	2018
Nonspecific inhibition of erythropoiesis by short hairpin RNAs. Blood\| PubMed ID: 29728407	2018
The autophagy-activating kinase ULK1 mediates clearance of free α-globin in β-thalassemia. Science translational medicine\| PubMed ID: 31434755	2019
Neonatal platelet count trends during inhaled nitric oxide therapy. British journal of haematology\| PubMed ID: 31840227	2020
Thrombocytosis in an infant with a mutation: a case report. Platelets\| PubMed ID: 32319342	2021
Tropomyosin 1 genetically constrains in vitro hematopoiesis. BMC biology\| PubMed ID: 32408895	2020
Genetic colocalization atlas points to common regulatory sites and genes for hematopoietic traits and hematopoietic contributions to disease phenotypes. BMC medical genomics\| PubMed ID: 32600345	2020
Genetic determinants of increased body mass index mediate the effect of smoking on increased risk for type 2 diabetes but not coronary artery disease. Human molecular genetics\| PubMed ID: 32833022	2020
Extreme thrombocytosis is associated with critical illness and young age, but not increased thrombotic risk, in hospitalized pediatric patients. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 32979018	2020
Airway emergency management in a pediatric hospital before and during the COVID-19 pandemic. medRxiv : the preprint server for health sciences\| PubMed ID: 32995823	2020
Airway emergency management in a pediatric hospital before and during the COVID-19 pandemic. International journal of pediatric otorhinolaryngology\| PubMed ID: 33130467	2020
Mechanistic and Translational Advances Using iPSC-Derived Blood Cells. Journal of Experimental Pathology\| PubMed ID: 33768218	2020
High rate of extreme thrombocytosis indicates bone marrow hyperactivity and splenic dysfunction among congenital diaphragmatic hernia patients. Platelets\| PubMed ID: 34697983	2022
Body mass index and adipose distribution have opposing genetic impacts on human blood traits. eLife\| PubMed ID: 35166671	2022
TSABL: Trait Specific Annotation Based Locus predictor. BMC genomics\| PubMed ID: 35705896	2022
Genetically influenced tobacco and alcohol use behaviors impact erythroid trait variation. medRxiv : the preprint server for health sciences\| PubMed ID: 37205362	2023
Generation of a human knockout iPSC line. bioRxiv : the preprint server for biology\| PubMed ID: 37205377	2023
Mendelian randomization analyses clarify the effects of height on cardiovascular diseases. medRxiv : the preprint server for health sciences\| PubMed ID: 37205563	2023
Generation of a human Tropomyosin 1 knockout iPSC line. Stem cell research\| PubMed ID: 37422949	2023
Neonatal Thrombocytopenia as a Presenting Finding in de novo Pyruvate Kinase Deficiency. Neonatology\| PubMed ID: 37473739	2023
Tropomyosin 1 deficiency facilitates cell state transitions to enhance hemogenic endothelial cell specification during hematopoiesis. bioRxiv : the preprint server for biology\| PubMed ID: 37693628	2023
Phosphoproteomics reveals content and signaling differences between neonatal and adult platelets. bioRxiv : the preprint server for biology\| PubMed ID: 37745418	2023
Quantitative label-free mass spectrometry reveals content and signaling differences between neonatal and adult platelets. Journal of thrombosis and haemostasis : JTH\| PubMed ID: 38160730	2023
Modeling primitive and definitive erythropoiesis with induced pluripotent stem cells. Blood advances\| PubMed ID: 38290102	2024