Jason Scragg

Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2024

Other Publications

Article	Year
Analysis of oxygen-sensitive human cardiac L-type Ca2+ channel alpha1C subunit (hHT Isoform). Methods in enzymology\| PubMed ID: 15063682	2004
Testosterone is a potent inhibitor of L-type Ca(2+) channels. Biochemical and biophysical research communications\| PubMed ID: 15120629	2004
Alzheimer's amyloid peptides mediate hypoxic up-regulation of L-type Ca2+ channels. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 15494446	2005
Constitutive activity of endogenous receptors by inducible Gq overexpression. Biochemical and biophysical research communications\| PubMed ID: 15883008	2005
Constitutive activity of human angiotensin II type-1 receptors by Gq overexpression. Biochemical and biophysical research communications\| PubMed ID: 15992776	2005
A central role for ROS in the functional remodelling of L-type Ca2+ channels by hypoxia. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 16321794	2005
Molecular requirements for L-type Ca2+ channel blockade by testosterone. Cell calcium\| PubMed ID: 17173968	2007
H2O 2-stimulated Ca2+ influx via TRPM2 is not the sole determinant of subsequent cell death. Pflugers Archiv : European journal of physiology\| PubMed ID: 18043941	2008
Modulation of hTREK-1 by carbon monoxide. Neuroreport\| PubMed ID: 18303579	2008
Carbon monoxide inhibits L-type Ca2+ channels via redox modulation of key cysteine residues by mitochondrial reactive oxygen species. The Journal of biological chemistry\| PubMed ID: 18596041	2008
Ion channels as effectors in carbon monoxide signaling. Communicative & integrative biology\| PubMed ID: 19641743	2009
Hypoxia and neurodegeneration. Annals of the New York Academy of Sciences\| PubMed ID: 19845619	2009
Carbon monoxide protects against oxidant-induced apoptosis via inhibition of Kv2.1. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 21248240	2011
Modulation of ion channels by hydrogen sulfide. Antioxidants & redox signaling\| PubMed ID: 22074224	2012
Cellular consequences of the expression of Alzheimer's disease-causing presenilin 1 mutations in human neuroblastoma (SH-SY5Y) cells. Brain research\| PubMed ID: 22297172	2012
Carbon monoxide mediates the anti-apoptotic effects of heme oxygenase-1 in medulloblastoma DAOY cells via K+ channel inhibition. The Journal of biological chemistry\| PubMed ID: 22593583	2012
Carbon monoxide induces cardiac arrhythmia via induction of the late Na+ current. American journal of respiratory and critical care medicine\| PubMed ID: 22822026	2012
Carbon monoxide inhibition of Cav3.2 T-type Ca2+ channels reveals tonic modulation by thioredoxin. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 23671274	2013
Inhibition of the cardiac Na⁺ channel Nav1.5 by carbon monoxide. The Journal of biological chemistry\| PubMed ID: 24719320	2014
Heme oxygenase-1 regulates cell proliferation via carbon monoxide-mediated inhibition of T-type Ca2+ channels. Pflugers Archiv : European journal of physiology\| PubMed ID: 24744106	2015
Hydrogen sulfide inhibits Cav3.2 T-type Ca2+ channels. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 25183670	2014
Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel. Journal of cell science\| PubMed ID: 25413349	2015
H2S does not regulate proliferation via T-type Ca2+ channels. Biochemical and biophysical research communications\| PubMed ID: 25918023	2015
Heme Oxygenase-1 Influences Apoptosis via CO-mediated Inhibition of K+ Channels. Advances in experimental medicine and biology\| PubMed ID: 26303499	2015
Inhibition of T-type Ca2+ Channels by Hydrogen Sulfide. Advances in experimental medicine and biology\| PubMed ID: 26303500	2015
Regulation of the T-type Ca(2+) channel Cav3.2 by hydrogen sulfide: emerging controversies concerning the role of H2 S in nociception. The Journal of physiology\| PubMed ID: 26804000	2016
Redox-Dependent Modulation of T-Type Ca(2+) Channels in Sensory Neurons Contributes to Acute Anti-Nociceptive Effect of Substance P. Antioxidants & redox signaling\| PubMed ID: 27306612	2016
Heme oxygenase-1 derived carbon monoxide suppresses Aβ toxicity in astrocytes. Cell death & disease\| PubMed ID: 28617444	2017
A key role for peroxynitrite-mediated inhibition of cardiac ERG (Kv11.1) K channels in carbon monoxide-induced proarrhythmic early afterdepolarizations. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 28743763	2017
Multiple mechanisms mediating carbon monoxide inhibition of the voltage-gated K channel Kv1.5. Cell death & disease\| PubMed ID: 29095440	2017
Piezo1 channel activation mimics high glucose as a stimulator of insulin release. Scientific reports\| PubMed ID: 31727906	2019
Unique Transcriptome Signature Distinguishes Patients With Heart Failure With Myopathy. Journal of the American Heart Association\| PubMed ID: 32892688	2020
Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis. Nature communications\| PubMed ID: 33772024	2021
Kv1.3 voltage-gated potassium channels link cellular respiration to proliferation through a non-conducting mechanism. Cell death & disease\| PubMed ID: 33828089	2021
Hydrogen sulfide regulates hippocampal neuron excitability via S-sulfhydration of Kv2.1. Scientific reports\| PubMed ID: 33854181	2021
Inhibition of the voltage-gated potassium channel Kv1.5 by hydrogen sulfide attenuates remodeling through S-nitrosylation-mediated signaling. Communications biology\| PubMed ID: 37336943	2023