Kari Hemminki

Laboratory of Translational Cancer Genomics, Charles University

Affiliated withCharles University German Cancer Research Center

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2024

Other Publications

Article	Year
A gene-wide investigation on polymorphisms in the taste receptor 2R14 (TAS2R14) and susceptibility to colorectal cancer. BMC medical genetics\| PubMed ID: 20534144	2010
Polymorphisms of genes coding for ghrelin and its receptor in relation to colorectal cancer risk: a two-step gene-wide case-control study. BMC gastroenterology\| PubMed ID: 20920174	2010
Association between TAS2R38 gene polymorphisms and colorectal cancer risk: a case-control study in two independent populations of Caucasian origin. PloS one\| PubMed ID: 21674048	2011
A comprehensive investigation on common polymorphisms in the MDR1/ABCB1 transporter gene and susceptibility to colorectal cancer. PloS one\| PubMed ID: 22396794	2012
Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases. BMC medical genetics\| PubMed ID: 23036011	2012
Single nucleotide polymorphisms within interferon signaling pathway genes are associated with colorectal cancer susceptibility and survival. PloS one\| PubMed ID: 25350395	2014
Structural chromosomal aberrations as potential risk markers in incident cancer patients. Mutagenesis\| PubMed ID: 25800034	2015
Interactions of DNA repair gene variants modulate chromosomal aberrations in healthy subjects. Carcinogenesis\| PubMed ID: 26354780	2015
Genetic variation in the major mitotic checkpoint genes associated with chromosomal aberrations in healthy humans. Cancer letters\| PubMed ID: 27424524	2016
Genomewide association study on monoclonal gammopathy of unknown significance (MGUS). European journal of haematology\| PubMed ID: 28375557	2017
Bleomycin-induced chromosomal damage and shortening of telomeres in peripheral blood lymphocytes of incident cancer patients. Genes, chromosomes & cancer\| PubMed ID: 29052312	2018
Investigation of single and synergic effects of NLRC5 and PD-L1 variants on the risk of colorectal cancer. PloS one\| PubMed ID: 29408916	2018
Short article: Influence of regulatory NLRC5 variants on colorectal cancer survival and 5-fluorouracil-based chemotherapy. European journal of gastroenterology & hepatology\| PubMed ID: 29762254	2018
Coding variants in NOD-like receptors: An association study on risk and survival of colorectal cancer. PloS one\| PubMed ID: 29928061	2018
Genetic variation associated with chromosomal aberration frequency: A genome-wide association study. Environmental and molecular mutagenesis\| PubMed ID: 30368896	2019
Genetic variation of acquired structural chromosomal aberrations. Mutation research. Genetic toxicology and environmental mutagenesis\| PubMed ID: 30389156	2018
Genome-wide association study of monoclonal gammopathy of unknown significance (MGUS): comparison with multiple myeloma. Leukemia\| PubMed ID: 30737484	2019
Single nucleotide polymorphisms within MUC4 are associated with colorectal cancer survival. PloS one\| PubMed ID: 31091244	2019
Distinct pathways associated with chromosomal aberration frequency in a cohort exposed to genotoxic compounds compared to general population. Mutagenesis\| PubMed ID: 31586183	2019
Eight novel loci implicate shared genetic etiology in multiple myeloma, AL amyloidosis, and monoclonal gammopathy of unknown significance. Leukemia\| PubMed ID: 31695157	2020
Epistatic effect of TLR3 and cGAS-STING-IKKε-TBK1-IFN signaling variants on colorectal cancer risk. Cancer medicine\| PubMed ID: 31869529	2020
Genetic predisposition for multiple myeloma. Leukemia\| PubMed ID: 31913320	2020
TERT promoter mutations in actinic keratosis before and after treatment. International journal of cancer\| PubMed ID: 31970758	2020
Association between tumor characteristics and second primary cancers with cutaneous melanoma survival: A nationwide cohort study. Pigment cell & melanoma research\| PubMed ID: 32012479	2020
Second Primary Cancers in Melanoma Patients Critically Shorten Survival. Clinical epidemiology\| PubMed ID: 32158273	2020
Identification of Familial Hodgkin Lymphoma Predisposing Genes Using Whole Genome Sequencing. Frontiers in bioengineering and biotechnology\| PubMed ID: 32211398	2020
Determining the Appropriate Risk-Adapted Screening Age for Familial Breast Cancer. JAMA oncology\| PubMed ID: 32379276	2020
Search for multiple myeloma risk factors using Mendelian randomization. Blood advances\| PubMed ID: 32433745	2020
A Germline Mutation in the Gene Is a Candidate for Familial Non-Medullary Thyroid Cancer. Cancers\| PubMed ID: 32492864	2020
Genomic imprinting analyses identify maternal effects as a cause of phenotypic variability in type 1 diabetes and rheumatoid arthritis. Scientific reports\| PubMed ID: 32665606	2020
Familial risks between Graves disease and Hashimoto thyroiditis and other autoimmune diseases in the population of Sweden. Journal of translational autoimmunity\| PubMed ID: 32743538	2020
Informing patients about their mutation tests: CDKN2A c.256G>A in melanoma as an example. Hereditary cancer in clinical practice\| PubMed ID: 32760473	2020
Incidence Differences Between First Primary Cancers and Second Primary Cancers Following Skin Squamous Cell Carcinoma as Etiological Clues. Clinical epidemiology\| PubMed ID: 32821171	2020
Rate differences between first and second primary cancers may outline immune dysfunction as a key risk factor. Cancer medicine\| PubMed ID: 32960498	2020
Cancer Predisposition Genes in Cancer-Free Families. Cancers\| PubMed ID: 32992489	2020
Chromosomal damage and telomere length in peripheral blood lymphocytes of cancer patients. Oncology reports\| PubMed ID: 33000239	2020
Familial associations between autoimmune hepatitis and primary biliary cholangitis and other autoimmune diseases. PloS one\| PubMed ID: 33079961	2020
Familial associations for Addison's disease and between Addison's disease and other autoimmune diseases. Endocrine connections\| PubMed ID: 33112839	2020
Impact of genetic polymorphisms in kinetochore and spindle assembly genes on chromosomal aberration frequency in healthy humans. Mutation research. Genetic toxicology and environmental mutagenesis\| PubMed ID: 33198934	2020
Familial associations for rheumatoid autoimmune diseases. Rheumatology advances in practice\| PubMed ID: 33241174	2020
Familial risks between giant cell arteritis and Takayasu arteritis and other autoimmune diseases in the population of Sweden. Scientific reports\| PubMed ID: 33257751	2020
Telomere length in peripheral blood lymphocytes related to genetic variation in telomerase, prognosis and clinicopathological features in breast cancer patients. Mutagenesis\| PubMed ID: 33367858	2020
A rare large duplication of MLH1 identified in Lynch syndrome. Hereditary cancer in clinical practice\| PubMed ID: 33468175	2021
Familial Risks between Pernicious Anemia and Other Autoimmune Diseases in the Population of Sweden. Autoimmune diseases\| PubMed ID: 33505716	2021
Characterization of rare germline variants in familial multiple myeloma. Blood cancer journal\| PubMed ID: 33583942	2021
Whole Exome Sequencing Identifies and Genes as Potentially Cancer Predisposing in Familial Colorectal Cancer. International journal of molecular sciences\| PubMed ID: 33673279	2021
DNA repair gene polymorphisms and chromosomal aberrations in healthy, nonsmoking population. DNA repair\| PubMed ID: 33676360	2021
Whole Genome Sequencing Prioritizes , and as Possible Predisposition Genes for Familial Non-Medullary Thyroid Cancer. Frontiers in endocrinology\| PubMed ID: 33692755	2021
Polymorphisms within Autophagy-Related Genes Influence the Risk of Developing Colorectal Cancer: A Meta-Analysis of Four Large Cohorts. Cancers\| PubMed ID: 33809172	2021
A Novel Low-Risk Germline Variant in the SH2 Domain of the SRC Gene Affects Multiple Pathways in Familial Colorectal Cancer. Journal of personalized medicine\| PubMed ID: 33916261	2021
Incidence trends in bladder and lung cancers between Denmark, Finland and Sweden may implicate oral tobacco (snuff/snus) as a possible risk factor. BMC cancer\| PubMed ID: 34034676	2021
Incidence trends in lung and bladder cancers in the Nordic Countries before and after the smoking epidemic. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)\| PubMed ID: 34074862	2022
Bladder and upper urinary tract cancers as first and second primary cancers. Cancer reports (Hoboken, N.J.)\| PubMed ID: 34114732	2021
Family history of early onset acute lymphoblastic leukemia is suggesting genetic associations. Scientific reports\| PubMed ID: 34117277	2021
Progress in survival in renal cell carcinoma through 50 years evaluated in Finland and Sweden. PloS one\| PubMed ID: 34157049	2021
DNA Repair Gene Polymorphisms and Chromosomal Aberrations in Exposed Populations. Frontiers in genetics\| PubMed ID: 34220964	2021
Search for AL amyloidosis risk factors using Mendelian randomization. Blood advances\| PubMed ID: 34228109	2021
Second Primary Cancers After Gastric Cancer, and Gastric Cancer as Second Primary Cancer. Clinical epidemiology\| PubMed ID: 34239328	2021
Survival in colon and rectal cancers in Finland and Sweden through 50 years. BMJ open gastroenterology\| PubMed ID: 34272211	2021
Second Primary Cancers After Kidney Cancers, and Kidney Cancers as Second Primary Cancers. European urology open science\| PubMed ID: 34337496	2021
Combinations of Low-Frequency Genetic Variants Might Predispose to Familial Pancreatic Cancer. Journal of personalized medicine\| PubMed ID: 34357098	2021
Second Primary Cancers After Liver, Gallbladder and Bile Duct Cancers, and These Cancers as Second Primary Cancers. Clinical epidemiology\| PubMed ID: 34377034	2021
Epidemiology, genetics and treatment of multiple myeloma and precursor diseases. International journal of cancer\| PubMed ID: 34398972	2021
Family History of Head and Neck Cancers. Cancers\| PubMed ID: 34439270	2021
Incidence, mortality and survival in multiple myeloma compared to other hematopoietic neoplasms in Sweden up to year 2016. Scientific reports\| PubMed ID: 34446811	2021
Familial Risks and Proportions Describing Population Landscape of Familial Cancer. Cancers\| PubMed ID: 34503195	2021
Types of second primary cancer influence overall survival in cutaneous melanoma. BMC cancer\| PubMed ID: 34663263	2021
Incidence, mortality and survival in malignant pleural mesothelioma before and after asbestos in Denmark, Finland, Norway and Sweden. BMC cancer\| PubMed ID: 34749677	2021
Prevalence of the GFI1-36N SNP in Multiple Myeloma Patients and Its Impact on the Prognosis. Frontiers in oncology\| PubMed ID: 34760702	2021
The Asthma Family Tree: Evaluating Associations Between Childhood, Parental, and Grandparental Asthma in Seven Chinese Cities. Frontiers in pediatrics\| PubMed ID: 34778126	2021
Survival in bladder and upper urinary tract cancers in Finland and Sweden through 50 years. PloS one\| PubMed ID: 34982793	2022
Functional dissection of inherited non-coding variation influencing multiple myeloma risk. Nature communications\| PubMed ID: 35013207	2022
T- and B-Cells in the Inner Invasive Margin of Hepatocellular Carcinoma after Resection Associate with Favorable Prognosis. Cancers\| PubMed ID: 35158872	2022
Germline Variants of and Predispose to Familial Colorectal Cancer. Cancers\| PubMed ID: 35158942	2022
Whole-Exome Sequencing Identifies a Novel Germline Variant in Gene in Familial Colorectal Cancer. International journal of molecular sciences\| PubMed ID: 35163215	2022
Long-term incidence and survival trends in cancer of the gallbladder and extrahepatic bile ducts in Denmark, Finland, Norway and Sweden with etiological implications related to Thorotrast. International journal of cancer\| PubMed ID: 35213036	2022
Incidence and survival in oral and pharyngeal cancers in Finland and Sweden through half century. BMC cancer\| PubMed ID: 35236321	2022
Genome-wide meta-analysis of monoclonal gammopathy of undetermined significance (MGUS) identifies risk loci impacting IRF-6. Blood cancer journal\| PubMed ID: 35418122	2022
Long-term incidence in hepatocellular carcinoma and intrahepatic bile duct cancer in Denmark, Finland, Norway and Sweden, role of Thorotrast? International journal of cancer\| PubMed ID: 35429352	2022
Familial Risks for Liver, Gallbladder and Bile Duct Cancers and for Their Risk Factors in Sweden, a Low-Incidence Country. Cancers\| PubMed ID: 35454845	2022
Cervical, vaginal and vulvar cancer incidence and survival trends in Denmark, Finland, Norway and Sweden with implications to treatment. BMC cancer\| PubMed ID: 35473606	2022
Whole exome sequencing identifies novel germline variants of SLC15A4 gene as potentially cancer predisposing in familial colorectal cancer. Molecular genetics and genomics : MGG\| PubMed ID: 35562597	2022
Validation and functional characterization of GWAS-identified variants for chronic lymphocytic leukemia: a CRuCIAL study. Blood cancer journal\| PubMed ID: 35581176	2022
Incidence and survival in laryngeal and lung cancers in Finland and Sweden through a half century. PloS one\| PubMed ID: 35622857	2022
Does a Multiple Myeloma Polygenic Risk Score Predict Overall Survival of Patients with Myeloma? Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 35700034	2022
Family history of any cancer for childhood leukemia patients in Sweden. EJHaem\| PubMed ID: 35844716	2021
CTNNB1 mutations, TERT polymorphism and CD8+ cell densities in resected hepatocellular carcinoma are associated with longer time to recurrence. BMC cancer\| PubMed ID: 35962322	2022
Genetic signature of differentiated thyroid carcinoma susceptibility: a machine learning approach. European thyroid journal\| PubMed ID: 35976137	2022
Survival trends in solid cancers in the Nordic countries through 50 years. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 36096040	2022
Personal comorbidities and their subsequent risks for liver, gallbladder and bile duct cancers. International journal of cancer\| PubMed ID: 36196489	2023
Monitoring of telomere dynamics in peripheral blood leukocytes in relation to colorectal cancer patients' outcomes. Frontiers in oncology\| PubMed ID: 36203452	2022
Survival trends in hematological malignancies in the Nordic countries through 50 years. Blood cancer journal\| PubMed ID: 36336699	2022
Long-term survival trends for primary liver and pancreatic cancers in the Nordic countries. JHEP reports : innovation in hepatology\| PubMed ID: 36352895	2022
Long Non-Coding RNA and microRNA Interplay in Colorectal Cancer and Their Effect on the Tumor Microenvironment. Cancers\| PubMed ID: 36358867	2022
Overview on population screening for carriers with germline BRCA mutation in China. Frontiers in oncology\| PubMed ID: 36439508	2022
Incidence, Mortality and Survival Trends in Breast Cancers Coincident with Introduction of Mammography in the Nordic Countries. Cancers\| PubMed ID: 36497389	2022
Activated Hepatic Stellate Cells in Hepatocellular Carcinoma: Their Role as a Potential Target for Future Therapies. International journal of molecular sciences\| PubMed ID: 36499616	2022
Author Correction: Functional dissection of inherited non-coding variation influencing multiple myeloma risk. Nature communications\| PubMed ID: 36513657	2022
Long-term survival trends in solid cancers in the Nordic countries marking timing of improvements. International journal of cancer\| PubMed ID: 36571455	2023
Investigation of Rare Non-Coding Variants in Familial Multiple Myeloma. Cells\| PubMed ID: 36611892	2022
An investigation of DNA damage and DNA repair in chemical carcinogenesis triggered by small-molecule xenobiotics and in cancer: Thirty years with the comet assay. Mutation research. Genetic toxicology and environmental mutagenesis\| PubMed ID: 36669813	2023
Autoimmune diseases as comorbidities for liver, gallbladder, and biliary duct cancers in Sweden. Cancer\| PubMed ID: 36715017	2023
Survival in Colon, Rectal and Small Intestinal Cancers in the Nordic Countries through a Half Century. Cancers\| PubMed ID: 36765946	2023
Response to letter entitled: Re: Survival trends in solid cancers in the Nordic countries through 50 years. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 36792396	2023
Survival in hematological malignancies in the Nordic countries through a half century with correlation to treatment. Leukemia\| PubMed ID: 36828868	2023
Survival in gastric and esophageal cancers in the Nordic countries through a half century. Cancer medicine\| PubMed ID: 36846972	2023
Are population level familial risks and germline genetics meeting each other? Hereditary cancer in clinical practice\| PubMed ID: 36882784	2023
GWAS-Identified Variants for Obesity Do Not Influence the Risk of Developing Multiple Myeloma: A Population-Based Study and Meta-Analysis. International journal of molecular sciences\| PubMed ID: 37047000	2023
Re: Mark N. Brook, Holly Ní Raghallaigh, Koveela Govindasami, et al. Family History of Prostate Cancer and Survival Outcomes in the UK Genetic Prostate Cancer Study. Eur Urol 2023;83:257-66. European urology\| PubMed ID: 37061447	2023
Survival in melanoma in the nordic countries into the era of targeted and immunological therapies. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 37068406	2023
Survival in Lung Cancer in the Nordic Countries Through A Half Century. Clinical epidemiology\| PubMed ID: 37153073	2023
Theranostics Nanomedicine Applications for Colorectal Cancer and Metastasis: Recent Advances. International journal of molecular sciences\| PubMed ID: 37175627	2023
Do GWAS-Identified Risk Variants for Chronic Lymphocytic Leukemia Influence Overall Patient Survival and Disease Progression? International journal of molecular sciences\| PubMed ID: 37175717	2023
Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization. International journal of molecular sciences\| PubMed ID: 37239846	2023
Survival in Kidney and Bladder Cancers in Four Nordic Countries through a Half Century. Cancers\| PubMed ID: 37345119	2023
Population-Attributable Fractions of Personal Comorbidities for Liver, Gallbladder, and Bile Duct Cancers. Cancers\| PubMed ID: 37370702	2023
Association between intake of the n-3 polyunsaturated fatty acid docosahexaenoic acid (n-3 PUFA DHA) and reduced risk of ovarian cancer: A systematic Mendelian Randomization study. Clinical nutrition (Edinburgh, Scotland)\| PubMed ID: 37421851	2023
Survival, Incidence, and Mortality Trends in Female Cancers in the Nordic Countries. Obstetrics and gynecology international\| PubMed ID: 37457920	2023
Conditional survival in breast cancer up to 10 years in the Nordic countries. Cancer medicine\| PubMed ID: 37578395	2023
Conditional Survival in Prostate Cancer in the Nordic Countries Elucidates the Timing of Improvements. Cancers\| PubMed ID: 37627160	2023
Early mortality critically impedes improvements in thyroid cancer survival through a half century. European journal of endocrinology\| PubMed ID: 37675794	2023
Steady survival improvements in soft tissue and bone sarcoma in the Nordic countries through 50 years. Cancer epidemiology\| PubMed ID: 37679266	2023
Long-Term Periodic and Conditional Survival Trends in Prostate, Testicular, and Penile Cancers in the Nordic Countries, Marking Timing of Improvements. Cancers\| PubMed ID: 37686536	2023
Identification of novel genetic loci for risk of multiple myeloma by functional annotation. Leukemia\| PubMed ID: 37723249	2023
miRNA and lncRNA as potential tissue biomarkers in hepatocellular carcinoma. Non-coding RNA research\| PubMed ID: 38075204	2024
Survival in oral and pharyngeal cancers is catching up with laryngeal cancer in the NORDIC countries through a half century. Cancer medicine\| PubMed ID: 38164108	2024
Prognostic role of macrophages and mast cells in the microenvironment of hepatocellular carcinoma after resection. BMC cancer\| PubMed ID: 38287290	2024
Genetic And Environmental Associations Of Nonspecific Chromosomal Aberrations. Mutagenesis\| PubMed ID: 38422374	2024
Major improvement in thyroid cancer survival of elderly patients in the Nordic countries. European journal of endocrinology\| PubMed ID: 38436478	2024
Large differencies in age-specific survival in multiple myeloma in the nordic countries. Blood cancer journal\| PubMed ID: 38467614	2024
Age-specific survival in acute myeloid leukemia in the Nordic countries through a half century. Blood cancer journal\| PubMed ID: 38480693	2024
Critical survival periods in prostate cancer in Sweden explored by conditional survival analysis. Cancer medicine\| PubMed ID: 38545829	2024