Don D Sin

UBC Centre for Heart Lung Innovation, St. Paul’s Hospital

Affiliated withSt. Paul’s Hospital University of British Columbia

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2024

Other Publications

Article	Year
Effects of inhaled corticosteroids on sputum cell counts in stable chronic obstructive pulmonary disease: a systematic review and a meta-analysis. BMC pulmonary medicine\| PubMed ID: 15707484	2005
The relationship between stage 1 and 2 non-small cell lung cancer and lung function in men and women. BMC pulmonary medicine\| PubMed ID: 16451726	2006
Survival after lung volume reduction in chronic obstructive pulmonary disease: insights from small airway pathology. American journal of respiratory and critical care medicine\| PubMed ID: 17556723	2007
Circulating surfactant protein D as a potential lung-specific biomarker of health outcomes in COPD: a pilot study. BMC pulmonary medicine\| PubMed ID: 17922919	2007
The influence of gender on the effects of aspirin in preventing myocardial infarction. BMC medicine\| PubMed ID: 17949479	2007
Airway wall thickness assessed using computed tomography and optical coherence tomography. American journal of respiratory and critical care medicine\| PubMed ID: 18310475	2008
Computed tomography scan for atherosclerosis and emphysema: a great hope or a great hype? The Canadian journal of cardiology\| PubMed ID: 18464941	2008
Particulate matter exposure induces persistent lung inflammation and endothelial dysfunction. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 18469117	2008
Acute exacerbation of chronic obstructive pulmonary disease: influence of social factors in determining length of hospital stay and readmission rates. Canadian respiratory journal\| PubMed ID: 18949105	2008
Treatment of mild chronic obstructive pulmonary disease. International journal of chronic obstructive pulmonary disease\| PubMed ID: 19281074	2008
Associations of IL6 polymorphisms with lung function decline and COPD. Thorax\| PubMed ID: 19359268	2009
Marijuana and chronic obstructive lung disease: a population-based study. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne\| PubMed ID: 19364790	2009
Connective tissue-activating peptide III: a novel blood biomarker for early lung cancer detection. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 19414677	2009
Beta-blockers and health-related quality of life in patients with peripheral arterial disease and COPD. International journal of chronic obstructive pulmonary disease\| PubMed ID: 19516916	2009
Integrative approach to quality assessment of medical journals using impact factor, eigenfactor, and article influence scores. PloS one\| PubMed ID: 20419115	2010
The effects of long-acting bronchodilators on total mortality in patients with stable chronic obstructive pulmonary disease. Respiratory research\| PubMed ID: 20459831	2010
Potential role of stem cells in management of COPD. International journal of chronic obstructive pulmonary disease\| PubMed ID: 20463889	2010
Quantification of lung surface area using computed tomography. Respiratory research\| PubMed ID: 21040527	2010
Serum PARC/CCL-18 concentrations and health outcomes in chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine\| PubMed ID: 21216880	2011
Improved patient outcome with smoking cessation: when is it too late? International journal of chronic obstructive pulmonary disease\| PubMed ID: 21814462	2011
Effect of gene environment interactions on lung function and cardiovascular disease in COPD. International journal of chronic obstructive pulmonary disease\| PubMed ID: 21814463	2011
Small-airway obstruction and emphysema in chronic obstructive pulmonary disease. The New England journal of medicine\| PubMed ID: 22029978	2011
The relationship of systemic inflammation to prior hospitalization in adult patients with cystic fibrosis. BMC pulmonary medicine\| PubMed ID: 22333132	2012
The lung tissue microbiome in chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine\| PubMed ID: 22427533	2012
What to do when a smoker's CT scan is "normal"?: Implications for lung cancer screening. Chest\| PubMed ID: 22553261	2012
The relationship between telomere length and mortality in chronic obstructive pulmonary disease (COPD). PloS one\| PubMed ID: 22558169	2012
Novel properties of statins: suppression of the systemic and bone marrow responses induced by exposure to ambient particulate matter (PM(10)) air pollution. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 22797249	2012
Genome-wide study identifies two loci associated with lung function decline in mild to moderate COPD. Human genetics\| PubMed ID: 22986903	2013
Effects of inhaled corticosteroids on airway inflammation in chronic obstructive pulmonary disease: a systematic review and meta-analysis. International journal of chronic obstructive pulmonary disease\| PubMed ID: 23055709	2012
Lung eQTLs to help reveal the molecular underpinnings of asthma. PLoS genetics\| PubMed ID: 23209423	2012
Epidemic of lung cancer in patients with HIV infection. Chest\| PubMed ID: 23381313	2013
Oxidative stress in chronic obstructive pulmonary disease: a lung and systemic process. Canadian respiratory journal\| PubMed ID: 23457671	2013
Bronchodilator responsiveness and reported respiratory symptoms in an adult population. PloS one\| PubMed ID: 23554960	2013
The relation of serum myeloperoxidase to disease progression and mortality in patients with chronic obstructive pulmonary disease (COPD). PloS one\| PubMed ID: 23637811	2013
Biomarkers in airway diseases. Canadian respiratory journal\| PubMed ID: 23762888	2013
Refining susceptibility loci of chronic obstructive pulmonary disease with lung eqtls. PloS one\| PubMed ID: 23936167	2013
Immunoglobulin G4-related lung disease: a disease with many different faces. Canadian respiratory journal\| PubMed ID: 24093112	2013
Tumour necrosis factor receptor-75 and risk of COPD exacerbation in the azithromycin trial. The European respiratory journal\| PubMed ID: 24136332	2014
Club cell protein 16 and disease progression in chronic obstructive pulmonary disease. American journal of respiratory and critical care medicine\| PubMed ID: 24245748	2013
Pro-surfactant protein B as a biomarker for lung cancer prediction. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 24248694	2013
DNA methylation is globally disrupted and associated with expression changes in chronic obstructive pulmonary disease small airways. American journal of respiratory cell and molecular biology\| PubMed ID: 24298892	2014
Budesonide/formoterol enhances the expression of pro Surfactant Protein-B in lungs of COPD patients. PloS one\| PubMed ID: 24386300	2013
Plasma sCD14 as a biomarker to predict pulmonary exacerbations in cystic fibrosis. PloS one\| PubMed ID: 24586701	2014
Bacterial microbiome of lungs in COPD. International journal of chronic obstructive pulmonary disease\| PubMed ID: 24591822	2014
Longer telomere length in COPD patients with α1-antitrypsin deficiency independent of lung function. PloS one\| PubMed ID: 24763308	2014
Whole exome re-sequencing implicates CCDC38 and cilia structure and function in resistance to smoking related airflow obstruction. PLoS genetics\| PubMed ID: 24786987	2014
Resource utilization and costs during the initial years of lung cancer screening with computed tomography in Canada. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer\| PubMed ID: 25105438	2014
Susceptibility loci for lung cancer are associated with mRNA levels of nearby genes in the lung. Carcinogenesis\| PubMed ID: 25187487	2014
A comparison between droplet digital and quantitative PCR in the analysis of bacterial 16S load in lung tissue samples from control and COPD GOLD 2. PloS one\| PubMed ID: 25329701	2014
Changes in the bacterial microbiota in gut, blood, and lungs following acute LPS instillation into mice lungs. PloS one\| PubMed ID: 25333938	2014
The burden of image based emphysema and bronchiolitis in HIV-infected individuals on antiretroviral therapy. PloS one\| PubMed ID: 25354261	2014
Genes related to emphysema are enriched for ubiquitination pathways. BMC pulmonary medicine\| PubMed ID: 25432663	2014
Genome-Wide Association Study Identification of Novel Loci Associated with Airway Responsiveness in Chronic Obstructive Pulmonary Disease. American journal of respiratory cell and molecular biology\| PubMed ID: 25514360	2015
Serum Bilirubin and Disease Progression in Mild COPD. Chest\| PubMed ID: 25539285	2015
Absolute leukocyte telomere length in HIV-infected and uninfected individuals: evidence of accelerated cell senescence in HIV-associated chronic obstructive pulmonary disease. PloS one\| PubMed ID: 25885433	2015
Host Response to the Lung Microbiome in Chronic Obstructive Pulmonary Disease. American journal of respiratory and critical care medicine\| PubMed ID: 25945594	2015
Airway Epithelial Expression Quantitative Trait Loci Reveal Genes Underlying Asthma and Other Airway Diseases. American journal of respiratory cell and molecular biology\| PubMed ID: 26102239	2016
Molecular mechanisms underlying variations in lung function: a systems genetics analysis. The Lancet. Respiratory medicine\| PubMed ID: 26404118	2015
Empowering family physicians to impart proper inhaler teaching to patients with chronic obstructive pulmonary disease and asthma. Canadian respiratory journal\| PubMed ID: 26436910	2015
The Effect of Statins on Blood Gene Expression in COPD. PloS one\| PubMed ID: 26462087	2015
Impact of Statins on Gene Expression in Human Lung Tissues. PloS one\| PubMed ID: 26535575	2015
Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. Nature communications\| PubMed ID: 26635082	2015
Associations of interleukin-1 gene cluster polymorphisms with C-reactive protein concentration and lung function decline in smoking-induced chronic obstructive pulmonary disease. International journal of clinical and experimental pathology\| PubMed ID: 26722511	2015
Impact of individualized care on readmissions after a hospitalization for acute exacerbation of COPD. International journal of chronic obstructive pulmonary disease\| PubMed ID: 26792986	2016
The Effect of Different Case Definitions of Current Smoking on the Discovery of Smoking-Related Blood Gene Expression Signatures in Chronic Obstructive Pulmonary Disease. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco\| PubMed ID: 27154971	2016
A Systematic Review of Diagnostic Biomarkers of COPD Exacerbation. PloS one\| PubMed ID: 27434033	2016
Individualized prediction of lung-function decline in chronic obstructive pulmonary disease. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne\| PubMed ID: 27486205	2016
COPD Exacerbation Biomarkers Validated Using Multiple Reaction Monitoring Mass Spectrometry. PloS one\| PubMed ID: 27525416	2016
A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 27658890	2016
Sex-Related Differences in Pulmonary Function following 6 Months of Cigarette Exposure: Implications for Sexual Dimorphism in Mild COPD. PloS one\| PubMed ID: 27788167	2016
The bronchial epithelial cell bacterial microbiome and host response in patients infected with human immunodeficiency virus. BMC pulmonary medicine\| PubMed ID: 27829448	2016
Findings on Thoracic Computed Tomography Scans and Respiratory Outcomes in Persons with and without Chronic Obstructive Pulmonary Disease: A Population-Based Cohort Study. PloS one\| PubMed ID: 27861566	2016
Emphysema Distribution and Diffusion Capacity Predict Emphysema Progression in Human Immunodeficiency Virus Infection. PloS one\| PubMed ID: 27902753	2016
Recurrent pneumothorax related to diffuse dendriform pulmonary ossification in genetically predisposed individual. Respirology case reports\| PubMed ID: 27999676	2017
Asthma-COPD Overlap Syndrome: What We Know and What We Don't. Tuberculosis and respiratory diseases\| PubMed ID: 28119742	2017
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets. Nature genetics\| PubMed ID: 28166213	2017
Longitudinal study of surrogate aging measures during human immunodeficiency virus seroconversion. Aging\| PubMed ID: 28237978	2017
C-reactive protein and N-terminal prohormone brain natriuretic peptide as biomarkers in acute exacerbations of COPD leading to hospitalizations. PloS one\| PubMed ID: 28328968	2017
Impact of a COPD comprehensive case management program on hospital length of stay and readmission rates. International journal of chronic obstructive pulmonary disease\| PubMed ID: 28356728	2017
Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease. Respiratory research\| PubMed ID: 28438154	2017
Integrative Genomics of Emphysema-Associated Genes Reveals Potential Disease Biomarkers. American journal of respiratory cell and molecular biology\| PubMed ID: 28459279	2017
Responsiveness to Ipratropium Bromide in Male and Female Patients with Mild to Moderate Chronic Obstructive Pulmonary Disease. EBioMedicine\| PubMed ID: 28461224	2017
Azithromycin and risk of COPD exacerbations in patients with and without Helicobacter pylori. Respiratory research\| PubMed ID: 28558695	2017
Longitudinal Computed Tomography and Magnetic Resonance Imaging of COPD: Thoracic Imaging Network of Canada (TINCan) Study Objectives. Chronic obstructive pulmonary diseases (Miami, Fla.)\| PubMed ID: 28848822	2014
Genetic variants associated with susceptibility to idiopathic pulmonary fibrosis in people of European ancestry: a genome-wide association study. The Lancet. Respiratory medicine\| PubMed ID: 29066090	2017
Surfactant protein D is a causal risk factor for COPD: results of Mendelian randomisation. The European respiratory journal\| PubMed ID: 29191953	2017
Reply. The Journal of allergy and clinical immunology\| PubMed ID: 29221816	2018
Phenotyping COPD exacerbations using imaging and blood-based biomarkers. International journal of chronic obstructive pulmonary disease\| PubMed ID: 29386890	2018
Inhaled Corticosteroids and Fractures in COPD: Can We Finally Put This to Bed? Chest\| PubMed ID: 29406210	2018
Response. Chest\| PubMed ID: 29406228	2018
Characterizing undiagnosed chronic obstructive pulmonary disease: a systematic review and meta-analysis. Respiratory research\| PubMed ID: 29415723	2018
Serum IgG subclass levels and risk of exacerbations and hospitalizations in patients with COPD. Respiratory research\| PubMed ID: 29444682	2018
Chronic Obstructive Pulmonary Disease as a Risk Factor for Cardiovascular Disease. A View from the SUMMIT. American journal of respiratory and critical care medicine\| PubMed ID: 29533679	2018
Leveraging lung tissue transcriptome to uncover candidate causal genes in COPD genetic associations. Human molecular genetics\| PubMed ID: 29547942	2018
The Impact of Care Specialty on Survival-Adjusted Medical Costs of COPD Patients After a Hospitalization: a longitudinal analysis. Journal of general internal medicine\| PubMed ID: 29611088	2018
COPD and cardiovascular diseases: now is the time for action! Thorax\| PubMed ID: 29622696	2018
The genetics of smoking in individuals with chronic obstructive pulmonary disease. Respiratory research\| PubMed ID: 29631575	2018
Crisis of COPD in China: the future is now. The Lancet. Respiratory medicine\| PubMed ID: 29650406	2018
Pulmonary Vascular Involvement in Chronic Obstructive Pulmonary Disease. Is There a Pulmonary Vascular Phenotype? American journal of respiratory and critical care medicine\| PubMed ID: 29746142	2018
Long-Term Trajectories of Mild Asthma in Adulthood and Risk Factors of Progression. The journal of allergy and clinical immunology. In practice\| PubMed ID: 29746917	2018
Relationship of Absolute Telomere Length With Quality of Life, Exacerbations, and Mortality in COPD. Chest\| PubMed ID: 30017346	2018
Imaging End Points in COPD Clinical Trials: Are We There Yet? Chest\| PubMed ID: 30044745	2018
Decreased microbiome diversity in the HIV small airway epithelium. Respiratory research\| PubMed ID: 30053882	2018
Multiethnic meta-analysis identifies ancestry-specific and cross-ancestry loci for pulmonary function. Nature communications\| PubMed ID: 30061609	2018
The diagnostic performance of patient symptoms in screening for COPD. Respiratory research\| PubMed ID: 30075717	2018
The Overlap of Lung Tissue Transcriptome of Smoke Exposed Mice with Human Smoking and COPD. Scientific reports\| PubMed ID: 30089872	2018
What triggers acute exacerbations of COPD? Why not ask the patient! Respirology (Carlton, Vic.)\| PubMed ID: 30106196	2019
Meta-analysis of exome array data identifies six novel genetic loci for lung function. Wellcome open research\| PubMed ID: 30175238	2018
COPD in China: From Crisis to Hope…. Chest\| PubMed ID: 30195339	2018
A letter from 'O Canada'. Respirology (Carlton, Vic.)\| PubMed ID: 30332712	2019
What are the long-term effects of smoked marijuana on lung health? CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne\| PubMed ID: 30348738	2018
Blood and sputum protein biomarkers for chronic obstructive pulmonary disease (COPD). Expert review of proteomics\| PubMed ID: 30362838	2018
Sputum Microbiome Is Associated with 1-Year Mortality after Chronic Obstructive Pulmonary Disease Hospitalizations. American journal of respiratory and critical care medicine\| PubMed ID: 30376356	2019
Current Controversies in Chronic Obstructive Pulmonary Disease. A Report from the Global Initiative for Chronic Obstructive Lung Disease Scientific Committee. Annals of the American Thoracic Society\| PubMed ID: 30427736	2019
A Streamlined Method for Quantification of Apolipoprotein A1 in Human Plasma by LC-MS/MS. Clinical chemistry\| PubMed ID: 30487190	2018
Inhaled corticosteroids and fractures in chronic obstructive pulmonary disease: current understanding and recommendations. Current opinion in pulmonary medicine\| PubMed ID: 30507646	2019
Inhaled corticosteroids in COPD: the final verdict is…. The European respiratory journal\| PubMed ID: 30545961	2018
Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study. The Lancet. Respiratory medicine\| PubMed ID: 30552067	2019
Introduction to precision medicine in COPD. The European respiratory journal\| PubMed ID: 30679189	2019
Accelerated lung aging and chronic obstructive pulmonary disease. Expert review of respiratory medicine\| PubMed ID: 30735057	2019
Phenotyping and outcomes of hospitalized COPD patients using rapid molecular diagnostics on sputum samples. International journal of chronic obstructive pulmonary disease\| PubMed ID: 30774328	2019
Smooth Muscle Cells Contribute the Majority of Foam Cells in ApoE (Apolipoprotein E)-Deficient Mouse Atherosclerosis. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 30786740	2019
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nature genetics\| PubMed ID: 30804560	2019
External Validation and Recalculation of the CODEX Index in COPD Patients. A 3CIAplus Cohort Study. COPD\| PubMed ID: 30870059	2019
Inhaled corticosteroids and the risk of lung cancer in COPD: a population-based cohort study. The European respiratory journal\| PubMed ID: 30956205	2019
Precision health: treating the individual patient with chronic obstructive pulmonary disease. The Medical journal of Australia\| PubMed ID: 30977152	2019
What's in the CART? A decision rule to predict short-term mortality during COPD exacerbations. Respirology (Carlton, Vic.)\| PubMed ID: 30985972	2019
Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nature genetics\| PubMed ID: 31110354	2019
Benralizumab for the Prevention of COPD Exacerbations. The New England journal of medicine\| PubMed ID: 31112385	2019
Impaired Sleep Quality in COPD Is Associated With Exacerbations: The CanCOLD Cohort Study. Chest\| PubMed ID: 31150638	2019
Differential lung tissue gene expression in males and females: implications for the susceptibility to develop COPD. The European respiratory journal\| PubMed ID: 31164434	2019
Blood biomarkers to predict short-term pulmonary exacerbation risk in children and adolescents with CF: A pilot study. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society\| PubMed ID: 31176669	2020
IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis. The European respiratory journal\| PubMed ID: 31196943	2019
Effect of short-term oral prednisone therapy on blood gene expression: a randomised controlled clinical trial. Respiratory research\| PubMed ID: 31382977	2019
Economic burden of multimorbidity in patients with severe asthma: a 20-year population-based study. Thorax\| PubMed ID: 31534029	2019
The pharmacogenomics of inhaled corticosteroids and lung function decline in COPD. The European respiratory journal\| PubMed ID: 31537701	2019
An Individualized Prediction Model for Long-term Lung Function Trajectory and Risk of COPD in the General Population. Chest\| PubMed ID: 31542453	2020
Trends in prescriptions and costs of inhaled medications in chronic obstructive pulmonary disease: a 19-year population-based study from Canada. International journal of chronic obstructive pulmonary disease\| PubMed ID: 31564848	2019
BMI is associated with FEV decline in chronic obstructive pulmonary disease: a meta-analysis of clinical trials. Respiratory research\| PubMed ID: 31665000	2019
Healthcare system encounters before COPD diagnosis: a registry-based longitudinal cohort study. Thorax\| PubMed ID: 31704794	2020
Diet and COPD: Are we what we eat? EClinicalMedicine\| PubMed ID: 31709393	2019
Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis. American journal of respiratory and critical care medicine\| PubMed ID: 31710517	2020
Asthma-COPD Overlap and Chronic Airflow Obstruction: Definitions, Management, and Unanswered Questions. The journal of allergy and clinical immunology. In practice\| PubMed ID: 31740296	2020
Widespread Sexual Dimorphism in the Transcriptome of Human Airway Epithelium in Response to Smoking. Scientific reports\| PubMed ID: 31772224	2019
Twenty-five years of Respirology: Advances in COPD. Respirology (Carlton, Vic.)\| PubMed ID: 31840889	2020
Sex differences in lymphoid follicles in COPD airways. Respiratory research\| PubMed ID: 32033623	2020
Contemporary Concise Review 2019: Chronic obstructive pulmonary disease. Respirology (Carlton, Vic.)\| PubMed ID: 32040982	2020
Identification and definition of asthma-COPD overlap: The CanCOLD study. Respirology (Carlton, Vic.)\| PubMed ID: 32064708	2020
Impact of marijuana smoking on lung function in older persons. The European respiratory journal\| PubMed ID: 32079671	2020
Response. Chest\| PubMed ID: 32145813	2020
The Acute COPD Exacerbation Prediction Tool (ACCEPT): a modelling study. The Lancet. Respiratory medicine\| PubMed ID: 32178776	2020
Avoiding immortal time bias in observational studies. The European respiratory journal\| PubMed ID: 32198270	2020
Self-initiated lifestyle interventions lead to potential insight into an effective, alternative, non-surgical therapy for mitochondrial disease associated multiple symmetric lipomatosis. Mitochondrion\| PubMed ID: 32234544	2020
Effects of sex and chronic cigarette smoke exposure on the mouse cecal microbiome. PloS one\| PubMed ID: 32251484	2020
Vitamin D Deficiency in COPD: Biomarker, Treatable Trait, or Just a Common Comorbidity? Chest\| PubMed ID: 32252921	2020
ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19. The European respiratory journal\| PubMed ID: 32269089	2020
COVID-19 and nicotine as a mediator of ACE-2. The European respiratory journal\| PubMed ID: 32350104	2020
Withdrawal of inhaled corticosteroids in COPD: a European Respiratory Society guideline. The European respiratory journal\| PubMed ID: 32366483	2020
Reply to: "Current smoking is not associated with COVID-19". The European respiratory journal\| PubMed ID: 32366490	2020
Predicting Severe Chronic Obstructive Pulmonary Disease Exacerbations. Developing a Population Surveillance Approach with Administrative Data. Annals of the American Thoracic Society\| PubMed ID: 32383971	2020
SARS-CoV-2 receptor ACE2 gene expression and RAAS inhibitors. The Lancet. Respiratory medicine\| PubMed ID: 32411576	2020
Smoking, ACE-2 and COVID-19: ongoing controversies. The European respiratory journal\| PubMed ID: 32430431	2020
Serum IgG Levels and Risk of COPD Hospitalization: A Pooled Meta-analysis. Chest\| PubMed ID: 32439504	2020
Phenotypic and functional translation of IL33 genetics in asthma. The Journal of allergy and clinical immunology\| PubMed ID: 32442646	2021
Particle depletion of diesel exhaust restores allergen-induced lung-protective surfactant protein D in human lungs. Thorax\| PubMed ID: 32467339	2020
External radiofrequency as a novel extracorporeal therapy for emphysema. The European respiratory journal\| PubMed ID: 32471932	2020
Association between COPD exacerbations and lung function decline during maintenance therapy. Thorax\| PubMed ID: 32532852	2020
A prospective safety and feasibility study of metered cryospray for patients with chronic bronchitis in COPD. The European respiratory journal\| PubMed ID: 32586881	2020
Various factors affect lipopolysaccharide sensitization in cell cultures. BioTechniques\| PubMed ID: 32654506	2020
Computed Tomography Vascular Tree-in-Bud: A Novel Prognostic Imaging Biomarker in COVID-19? American journal of respiratory and critical care medicine\| PubMed ID: 32687386	2020
Biomarkers in Chronic Obstructive Pulmonary Disease: The Gateway to Precision Medicine. Clinics in chest medicine\| PubMed ID: 32800193	2020
COVID-19 and COPD. The European respiratory journal\| PubMed ID: 32817205	2020
The Long-Term Burden of COPD Exacerbations During Maintenance Therapy and Lung Function Decline. International journal of chronic obstructive pulmonary disease\| PubMed ID: 32821093	2020
Protective effect of club cell secretory protein (CC-16) on COPD risk and progression: a Mendelian randomisation study. Thorax\| PubMed ID: 32839289	2020
COVID-19 in COPD: A growing concern. EClinicalMedicine\| PubMed ID: 32984790	2020
Abundance of Non-Polarized Lung Macrophages with Poor Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD). Biomedicines\| PubMed ID: 33050042	2020
The Role of Granzyme B Containing Cells in the Progression of Chronic Obstructive Pulmonary Disease. Tuberculosis and respiratory diseases\| PubMed ID: 33076634	2020
Cost Effectiveness of Case Detection Strategies for the Early Detection of COPD. Applied health economics and health policy\| PubMed ID: 33135094	2021
High eosinophil counts predict decline in FEV: results from the CanCOLD study. The European respiratory journal\| PubMed ID: 33303555	2021
Towards large-scale case-finding: training and validation of residual networks for detection of chronic obstructive pulmonary disease using low-dose CT. The Lancet. Digital health\| PubMed ID: 33328058	2020
Beta-blockers in chronic obstructive pulmonary disease: the good, the bad and the ugly. Current opinion in pulmonary medicine\| PubMed ID: 33332878	2021
ACE inhibition and cardiometabolic risk factors, lung and gene expression, and plasma ACE2 levels: a Mendelian randomization study. Royal Society open science\| PubMed ID: 33391794	2020
Gender modifies the effect of body mass index on lung function decline in mild-to-moderate COPD patients: a pooled analysis. Respiratory research\| PubMed ID: 33602241	2021
The Prevalence of Chronic Obstructive Pulmonary Disease (COPD) and the Heterogeneity of Risk Factors in the Canadian Population: Results from the Canadian Obstructive Lung Disease (COLD) Stu... International journal of chronic obstructive pulmonary disease\| PubMed ID: 33603357	2021
Multi-omics highlights ABO plasma protein as a causal risk factor for COVID-19. Human genetics\| PubMed ID: 33604698	2021
Aryl hydrocarbon receptor deficiency causes the development of chronic obstructive pulmonary disease through the integration of multiple pathogenic mechanisms. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 33605487	2021
Mild catalytic defects of tert rs61748181 polymorphism affect the clinical presentation of chronic obstructive pulmonary disease. Scientific reports\| PubMed ID: 33619289	2021
Olodaterol exerts anti-inflammatory effects on COPD airway epithelial cells. Respiratory research\| PubMed ID: 33622325	2021
Pulmonary Rehabilitation in a Post-COVID-19 World: Telerehabilitation as a New Standard in Patients with COPD. International journal of chronic obstructive pulmonary disease\| PubMed ID: 33642858	2021
IL-4Rα blockade reduces influenza-associated morbidity in a murine model of allergic asthma. Respiratory research\| PubMed ID: 33653328	2021
Microchip RT-PCR Detection of Nasopharyngeal SARS-CoV-2 Samples. The Journal of molecular diagnostics : JMD\| PubMed ID: 33706009	2021
Variants associated with expression have sex-differential effects on lung function. Wellcome open research\| PubMed ID: 33728380	2020
COPD and the risk of poor outcomes in COVID-19: A systematic review and meta-analysis. EClinicalMedicine\| PubMed ID: 33758801	2021
Clotting in COVID-19: Is It All in the Genes? American journal of respiratory cell and molecular biology\| PubMed ID: 33784208	2021
Inhaled corticosteroids downregulate SARS-CoV-2-related genes in COPD: results from a randomised controlled trial. The European respiratory journal\| PubMed ID: 33795322	2021
Macrophages with reduced expressions of classical M1 and M2 surface markers in human bronchoalveolar lavage fluid exhibit pro-inflammatory gene signatures. Scientific reports\| PubMed ID: 33859282	2021
IgG Levels and Mortality in Chronic Obstructive Pulmonary Disease. American journal of respiratory and critical care medicine\| PubMed ID: 33945775	2021
Vascular and renal telomere shortening in mice exposed to chronic intermittent hypoxia. Canadian journal of physiology and pharmacology\| PubMed ID: 33951396	2021
SARS-CoV-2 rapid antigen testing for departing passengers at Vancouver International Airport. Journal of travel medicine\| PubMed ID: 34046663	2021
Prioritization of candidate causal genes for asthma in susceptibility loci derived from UK Biobank. Communications biology\| PubMed ID: 34103634	2021
FAM13A as potential therapeutic target in modulating TGF-β-induced airway tissue remodeling in COPD. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 34105356	2021
Methylxanthines in COPD: yes to caffeine, no to theophylline. The European respiratory journal\| PubMed ID: 34112714	2021
Update on Asthma-COPD Overlap (ACO): A Narrative Review. International journal of chronic obstructive pulmonary disease\| PubMed ID: 34168440	2021
A mechanical test of the tenertaxis hypothesis for leukocyte diapedesis. The European physical journal. E, Soft matter\| PubMed ID: 34236552	2021
The impact of lockdown timing on COVID-19 transmission across US counties. EClinicalMedicine\| PubMed ID: 34308301	2021
Effects of Inhaled Corticosteroid/Long-Acting β-Agonist Combination on the Airway Microbiome of Patients with Chronic Obstructive Pulmonary Disease: A Randomized Controlled Clinical Trial (D... American journal of respiratory and critical care medicine\| PubMed ID: 34464242	2021
Disease activity in COPD: time to make imaging biomarkers a PET project? ERJ open research\| PubMed ID: 34476244	2021
Correction to: A mechanical test of the tenertaxis hypothesis forleukocyte diapedesis. The European physical journal. E, Soft matter\| PubMed ID: 34519902	2021
Epigenetic blood biomarkers of ageing and mortality in COPD. The European respiratory journal\| PubMed ID: 34561282	2021
Radiofrequency therapy improves exercise capacity of mice with emphysema. Scientific reports\| PubMed ID: 34625605	2021
Asthma-COPD Overlap: What Are the Important Questions? Chest\| PubMed ID: 34626594	2022
The molecular and cellular mechanisms associated with the destruction of terminal bronchioles in COPD. The European respiratory journal\| PubMed ID: 34675046	2022
Pulmonary rehabilitation in a postcoronavirus disease 2019 world: feasibility, challenges, and solutions. Current opinion in pulmonary medicine\| PubMed ID: 34690256	2022
Computed tomography total airway count predicts progression to COPD in at-risk smokers. ERJ open research\| PubMed ID: 34708120	2021
Airway luminal area and the resistive work of breathing during exercise in healthy young females and males. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 34709072	2021
Development of a Blood-based Transcriptional Risk Score for Chronic Obstructive Pulmonary Disease. American journal of respiratory and critical care medicine\| PubMed ID: 34739356	2022
Epigenetic marker of telomeric age is associated with exacerbations and hospitalizations in chronic obstructive pulmonary disease. Respiratory research\| PubMed ID: 34937547	2021
Ketogenic diet for mitochondrial disease: potential role in treating the Multiple Symmetric Lipomatosis phenotype associated with the common MT-TK genetic mutation. Orphanet journal of rare diseases\| PubMed ID: 35012599	2022
The Role of the Dynamic Lung Extracellular Matrix Environment on Fibroblast Morphology and Inflammation. Cells\| PubMed ID: 35053300	2022
Distinct bronchial microbiome precedes clinical diagnosis of lung cancer. Molecular cancer\| PubMed ID: 35255902	2022
Ambient Air Pollution and Dysanapsis: Associations with Lung Function and Chronic Obstructive Pulmonary Disease in the Canadian Cohort Obstructive Lung Disease Study. American journal of respiratory and critical care medicine\| PubMed ID: 35380941	2022
Airway Aging and Methylation Disruptions in HIV-associated Chronic Obstructive Pulmonary Disease. American journal of respiratory and critical care medicine\| PubMed ID: 35426765	2022
GETting to know the many causes and faces of COPD. The Lancet. Respiratory medicine\| PubMed ID: 35427529	2022
Software development to optimize the minimal detectable difference in human airway images captured using optical coherence tomography. Clinical physiology and functional imaging\| PubMed ID: 35522086	2022
Cigarette Smoking and Asthma. The journal of allergy and clinical immunology. In practice\| PubMed ID: 35533997	2022
Inhaled Corticosteroids Selectively Alter the Microbiome and Host Transcriptome in the Small Airways of Patients with Chronic Obstructive Pulmonary Disease. Biomedicines\| PubMed ID: 35625847	2022
The impact of IgG subclass deficiency on the risk of mortality in hospitalized patients with COPD. Respiratory research\| PubMed ID: 35641962	2022
Blood gene expression risk profiles and interstitial lung abnormalities: COPDGene and ECLIPSE cohort studies. Respiratory research\| PubMed ID: 35715807	2022
Airway Eosinophilia on Bronchoalveolar Lavage and the Risk of Exacerbations in COPD. Biomedicines\| PubMed ID: 35740433	2022
ACCEPT 2·0: Recalibrating and externally validating the Acute COPD exacerbation prediction tool (ACCEPT). EClinicalMedicine\| PubMed ID: 35898315	2022
Definition and Nomenclature of Chronic Obstructive Pulmonary Disease: Time for Its Revision. American journal of respiratory and critical care medicine\| PubMed ID: 35914087	2022
The relationship between the epigenetic aging biomarker "grimage" and lung function in both the airway and blood of people living with HIV: An observational cohort study. EBioMedicine\| PubMed ID: 35944348	2022
Pharmacotherapy considerations for morning symptoms in chronic obstructive pulmonary disease. Expert opinion on pharmacotherapy\| PubMed ID: 35986503	2022
Association of bronchial steroid inducible methylation quantitative trait loci with asthma and chronic obstructive pulmonary disease treatment response. Clinical and translational allergy\| PubMed ID: 36036237	2022
RETHINCking COPD - Bronchodilators for Symptomatic Tobacco-Exposed Persons with Preserved Lung Function? The New England journal of medicine\| PubMed ID: 36066080	2022
Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission. Lancet (London, England)\| PubMed ID: 36075255	2022
Combination therapy with long-acting bronchodilators and the risk of major adverse cardiovascular events in patients with COPD: a systematic review and meta-analysis. The European respiratory journal\| PubMed ID: 36137586	2023
Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma. Cells\| PubMed ID: 36230980	2022
Prognostic peripheral blood biomarkers at ICU admission predict COVID-19 clinical outcomes. Frontiers in immunology\| PubMed ID: 36451808	2022
Common Respiratory Pathogens Other Than in Small Airways are Associated With Neutrophilic Inflammation and Poor Health Status in Stable COPD Patients. Chronic obstructive pulmonary diseases (Miami, Fla.)\| PubMed ID: 36459695	2023
Reply: Association between triple therapy and major adverse cardiovascular events in COPD patients. The European respiratory journal\| PubMed ID: 36549713	2023
The Blood DNA Methylation Clock GrimAge Is a Robust Surrogate for Airway Epithelia Aging. Biomedicines\| PubMed ID: 36551848	2022
Physical Activity and Symptom Burden in COPD: The Canadian Obstructive Lung Disease Study. Chronic obstructive pulmonary diseases (Miami, Fla.)\| PubMed ID: 36563057	2023
The : the ERS flagship heads for the next frontier. The European respiratory journal\| PubMed ID: 36634923	2023
Is long COVID an autoimmune disease? The European respiratory journal\| PubMed ID: 36634924	2023
Systemic and Airway Epigenetic Disruptions Are Associated with Health Status in COPD. Biomedicines\| PubMed ID: 36672643	2023
IMplementing Predictive Analytics towards efficient COPD Treatments (IMPACT): protocol for a stepped-wedge cluster randomized impact study. Diagnostic and prognostic research\| PubMed ID: 36782301	2023
measurements of lung function using respiratory-gated micro-computed tomography in a smoke-exposure model of chronic obstructive pulmonary disease. Journal of medical imaging (Bellingham, Wash.)\| PubMed ID: 36818545	2023
Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary. American journal of respiratory and critical care medicine\| PubMed ID: 36856433	2023
Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary. Respirology (Carlton, Vic.)\| PubMed ID: 36856440	2023
Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary. The European respiratory journal\| PubMed ID: 36858443	2023
Impaired Spirometry and COPD Increase the Risk of Cardiovascular Disease: A Canadian Cohort Study. Chest\| PubMed ID: 36871842	2023
Global Initiative for Chronic Obstructive Lung Disease 2023 Report: GOLD Executive Summary. Archivos de bronconeumologia\| PubMed ID: 36933949	2023
Air pollution and COPD: GOLD 2023 committee report. The European respiratory journal\| PubMed ID: 36958741	2023
Characterization of the Lower Airways and Oral Microbiota in Healthy Young Persons in the Community. Biomedicines\| PubMed ID: 36979819	2023
The Importance of Early Chronic Obstructive Pulmonary Disease: A Lecture from 2022 Asian Pacific Society of Respirology. Tuberculosis and respiratory diseases\| PubMed ID: 37005090	2023
Chronic Obstructive Pulmonary Disease and the Airway Microbiome: What Respirologists Need to Know. Tuberculosis and respiratory diseases\| PubMed ID: 37038880	2023
Age-associated differences in the human lung extracellular matrix. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 37039368	2023
The need to streamline approval processes for clinical research in Canada. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne\| PubMed ID: 37040997	2023
Factors Associated with Attrition in a Longitudinal Cohort of Older Adults in the Community. Chronic obstructive pulmonary diseases (Miami, Fla.)\| PubMed ID: 37099700	2023
Microbial dysbiosis and the host airway epithelial response: insights into HIV-associated COPD using multi'omics profiling. Respiratory research\| PubMed ID: 37143066	2023
Short-term air pollution exposure and exacerbation events in mild to moderate COPD: a case-crossover study within the CanCOLD cohort. Thorax\| PubMed ID: 37147124	2023
GOLD COPD DOCUMENT 2023: a brief update for practicing cardiologists. Clinical research in cardiology : official journal of the German Cardiac Society\| PubMed ID: 37233751	2024
Blood Gene Expression and Immune Cell Subtypes Associated with Chronic Obstructive Pulmonary Disease Exacerbations. American journal of respiratory and critical care medicine\| PubMed ID: 37286295	2023
The GOLD 2023 proposed taxonomy: a new tool to determine COPD etiotypes. The European respiratory journal\| PubMed ID: 37290808	2023
An integrated cell atlas of the lung in health and disease. Nature medicine\| PubMed ID: 37291214	2023
Quantifying COPD as a risk factor for cardiac disease in a primary prevention cohort. The European respiratory journal\| PubMed ID: 37385658	2023
Predicting steroid responsiveness using airway smooth muscle in COPD: a HISTORIC study. The European respiratory journal\| PubMed ID: 37474151	2023
Post-COVID-19 dyspnoea and pulmonary imaging: a systematic review and meta-analysis. European respiratory review : an official journal of the European Respiratory Society\| PubMed ID: 37558261	2023
Phenotypes, Etiotypes, and Endotypes of Exacerbations of Chronic Obstructive Pulmonary Disease. American journal of respiratory and critical care medicine\| PubMed ID: 37560988	2023
Trends in hospital admissions for chronic obstructive pulmonary disease over 16 years in Canada. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne\| PubMed ID: 37696554	2023
NLR in CBC: A holy grail for biomarker research in COPD? Respirology (Carlton, Vic.)\| PubMed ID: 37696582	2023
A Cost-Effectiveness Analysis of Azithromycin for the Prevention of Acute Exacerbations of Chronic Obstructive Pulmonary Disease. Annals of the American Thoracic Society\| PubMed ID: 37703432	2023
Development of a unilateral porcine emphysema model induced by porcine pancreatic elastase. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 37767558	2023
Single-cell RNA sequencing of bronchoscopy specimens: development of a rapid minimal handling protocol. BioTechniques\| PubMed ID: 37815826	2023
Blood-based Transcriptomic and Proteomic Biomarkers of Emphysema. American journal of respiratory and critical care medicine\| PubMed ID: 37917913	2024
TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase. Nature communications\| PubMed ID: 37963864	2023
Genome-wide association study of preserved ratio impaired spirometry (PRISm). The European respiratory journal\| PubMed ID: 38097206	2024
Single-Cell Sequencing of Lung Macrophages and Monocytes Reveals Novel Therapeutic Targets in COPD. Cells\| PubMed ID: 38132091	2023
2024: your journal, my journal, our journal. The European respiratory journal\| PubMed ID: 38176701	2024
Mild airways obstruction: spirometric diagnostic pitfalls and solutions. Current opinion in pulmonary medicine\| PubMed ID: 38265250	2024
Granzyme B May Act as an Effector Molecule to Control the Inflammatory Process in COPD. COPD\| PubMed ID: 38314671	2024
Cluster Analysis to Identify Long COVID Phenotypes Using Xe Magnetic Resonance Imaging: A Multi-centre Evaluation. The European respiratory journal\| PubMed ID: 38331459	2024
What Single Cell RNA Sequencing Has Taught Us about Chronic Obstructive Pulmonary Disease. Tuberculosis and respiratory diseases\| PubMed ID: 38369875	2024
A Proposed Approach to Pulmonary Long COVID: A Viewpoint. The European respiratory journal\| PubMed ID: 38453258	2024
Type 2 airway inflammation in chronic obstructive pulmonary disease. The European respiratory journal\| PubMed ID: 38485148	2024
Exploring Mechanisms of Lipid Nanoparticle-Mucus Interactions in Healthy and Cystic Fibrosis Conditions. Advanced healthcare materials\| PubMed ID: 38563726	2024
Why Is BMI Related to COPD? Is It All in the Genes? American journal of respiratory and critical care medicine\| PubMed ID: 38593419	2024