Gary C. Sieck

Gary C. Sieck

Department of Physiology and Biomedical Engineering, Mayo Clinic

Affiliated withMayo Clinic

Research Area

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JoVE Journal Publications

ArticleTotal : 1
Year
Assessing Functional Recovery of Eupneic Diaphragm Activity Following Unilateral Cervical Spinal Cord Hemisection in Rats
Publication title

Cited by 5

2024

Other Publications

Article
Year
Cervical dorsal rhizotomy enhances serotonergic innervation of phrenic motoneurons and serotonin-dependent long-term facilitation of respiratory motor output in rats.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 9763486

1998
1999
2001
Diaphragm dysfunction in chronic obstructive pulmonary disease.

American journal of respiratory and critical care medicine| PubMed ID: 15849324

2005
Role of transient receptor potential C3 in TNF-alpha-enhanced calcium influx in human airway myocytes.

American journal of respiratory cell and molecular biology| PubMed ID: 16574942

2006
Regulation of store-operated Ca2+ entry by CD38 in human airway smooth muscle.

American journal of physiology. Lung cellular and molecular physiology| PubMed ID: 18178673

2008
Key aspects of phrenic motoneuron and diaphragm muscle development during the perinatal period.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 18403452

2008
Trophic factor expression in phrenic motor neurons.

Respiratory physiology & neurobiology| PubMed ID: 18708170

2008
2009
Effect of proinflammatory cytokines on regulation of sarcoplasmic reticulum Ca2+ reuptake in human airway smooth muscle.

American journal of physiology. Lung cellular and molecular physiology| PubMed ID: 19395670

2009
2009
The effect of denervation on protein synthesis and degradation in adult rat diaphragm muscle.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 19520837

2009
Retrograde labeling of phrenic motoneurons by intrapleural injection.

Journal of neuroscience methods| PubMed ID: 19559048

2009
Novel method for physiological recruitment of diaphragm motor units after upper cervical spinal cord injury.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 19628723

2009
2009
Neuromuscular adaptations to respiratory muscle inactivity.

Respiratory physiology & neurobiology| PubMed ID: 19744580

2009
Characterization of secophalloidin-induced force loss in cardiac myofibrils.

Journal of muscle research and cell motility| PubMed ID: 19763850

2009
Asthma and sarcoplasmic reticulum Ca2+ reuptake in airway smooth muscle.

American journal of physiology. Lung cellular and molecular physiology| PubMed ID: 19783641

2009
Correlation of respiratory activity of contralateral diaphragm muscles for evaluation of recovery following hemiparesis.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference| PubMed ID: 19965125

2009
Mechanisms underlying hypothermia-induced cardiac contractile dysfunction.

American journal of physiology. Heart and circulatory physiology| PubMed ID: 20023122

2010
Impairment of diaphragm muscle force and neuromuscular transmission after normothermic cardiopulmonary bypass: effect of low-dose inhaled CO.

American journal of physiology. Regulatory, integrative and comparative physiology| PubMed ID: 20089713

2010
2010
Diaphragm motor unit recruitment in rats.

Respiratory physiology & neurobiology| PubMed ID: 20620243

2010
Neuregulin-1 at synapses on phrenic motoneurons.

The Journal of comparative neurology| PubMed ID: 20878784

2010
2011
Chronic assessment of diaphragm muscle EMG activity across motor behaviors.

Respiratory physiology & neurobiology| PubMed ID: 21414423

2011
2011
Phrenic motor unit recruitment during ventilatory and non-ventilatory behaviors.

Respiratory physiology & neurobiology| PubMed ID: 21763470

2011
2011
2011
2012
2011
2012
2012
Mechanisms of intrinsic force in small human airways.

Respiratory physiology & neurobiology| PubMed ID: 22322114

2012
2012
2012
Inflammation alters regional mitochondrial Ca²+ in human airway smooth muscle cells.

American journal of physiology. Cell physiology| PubMed ID: 22673614

2012
Systems biology of skeletal muscle: fiber type as an organizing principle.

Wiley interdisciplinary reviews. Systems biology and medicine| PubMed ID: 22811254

2012
Caveolin-1 knockout mice exhibit airway hyperreactivity.

American journal of physiology. Lung cellular and molecular physiology| PubMed ID: 22923642

2012
2013
2013
2013
Neuromotor control in chronic obstructive pulmonary disease.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 23329816

2013
2013
Novel method for transdiaphragmatic pressure measurements in mice.

Respiratory physiology & neurobiology| PubMed ID: 23632282

2013
2013
2013
Diaphragm muscle sarcopenia in aging mice.

Experimental gerontology| PubMed ID: 23792145

2013
Respiratory muscle plasticity.

Comprehensive Physiology| PubMed ID: 23798306

2012
Impact of diaphragm muscle fiber atrophy on neuromotor control.

Respiratory physiology & neurobiology| PubMed ID: 23831121

2013
2013
Rebuttal from Gary C. Sieck and Carlos B. Mantilla.

The Journal of physiology| PubMed ID: 24187076

2013
Mechanical properties of respiratory muscles.

Comprehensive Physiology| PubMed ID: 24265238

2013
2014
Physiology's impact: stop ignoring the obvious-sex matters!

Physiology (Bethesda, Md.)| PubMed ID: 24382865

2014
Cigarette smoke-induced mitochondrial fragmentation and dysfunction in human airway smooth muscle.

American journal of physiology. Lung cellular and molecular physiology| PubMed ID: 24610934

2014
2014
2014
2015
Response to letter by Dr. Marc Hershenson (exposure of airway smooth muscle cells to cigarette smoke extract).

American journal of physiology. Lung cellular and molecular physiology| PubMed ID: 25128539

2014
TrkB kinase activity maintains synaptic function and structural integrity at adult neuromuscular junctions.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 25170066

2014
2014
Paradoxical use of tumor necrosis factor in treating pulmonary edema.

American journal of respiratory and critical care medicine| PubMed ID: 25221873

2014
2014
2014
2015
2015
Impact of unilateral denervation on transdiaphragmatic pressure.

Respiratory physiology & neurobiology| PubMed ID: 25641347

2015
Feasibility and reliability of quantifying passive muscle stiffness in young children by using shear wave ultrasound elastography.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine| PubMed ID: 25792582

2015
2015
Functional impact of diaphragm muscle sarcopenia in both male and female mice.

American journal of physiology. Lung cellular and molecular physiology| PubMed ID: 25934669

2015
Muscle weakness in critical illness.

American journal of respiratory and critical care medicine| PubMed ID: 25978566

2015
2015
2015
2016
Functional impact of sarcopenia in respiratory muscles.

Respiratory physiology & neurobiology| PubMed ID: 26467183

2016
2016
2015
2015
2016
2016
2016
2016
2016
2016
Hypothermia/rewarming disrupts excitation-contraction coupling in cardiomyocytes.

American journal of physiology. Heart and circulatory physiology| PubMed ID: 26993227

2016
2016
Diaphragm muscle sarcopenia in Fischer 344 and Brown Norway rats.

Experimental physiology| PubMed ID: 27126607

2016
2016
Aging-related changes in respiratory system mechanics and morphometry in mice.

American journal of physiology. Lung cellular and molecular physiology| PubMed ID: 27288490

2016
2016
2017
Functional Measurement of Respiratory Muscle Motor Behaviors Using Transdiaphragmatic Pressure.

Methods in molecular biology (Clifton, N.J.)| PubMed ID: 27492181

2016
2016
2017
2017
2017
Physiology in Perspective: Aging and Underlying Pathophysiology.

Physiology (Bethesda, Md.)| PubMed ID: 27927800

2017
2017
Physiology in Perspective: Homeostasis and Evolution.

Physiology (Bethesda, Md.)| PubMed ID: 28202620

2017
2017
TNFα enhances force generation in airway smooth muscle.

American journal of physiology. Lung cellular and molecular physiology| PubMed ID: 28385814

2017
Physiology in Perspective: The Importance of Integrative Physiology.

Physiology (Bethesda, Md.)| PubMed ID: 28404734

2017
TNFα decreases mitochondrial movement in human airway smooth muscle.

American journal of physiology. Lung cellular and molecular physiology| PubMed ID: 28473328

2017
2017
2017
Compensatory effects following unilateral diaphragm paralysis.

Respiratory physiology & neurobiology| PubMed ID: 28790008

2017
Physiology in Perspective: The Value of Integrative Physiology.

Physiology (Bethesda, Md.)| PubMed ID: 28794214

2017
Physiology in Perspective: Physiology Provides Insight into Health.

Physiology (Bethesda, Md.)| PubMed ID: 29021360

2017
Physiology in Perspective: Stem Cells and Regenerative Physiology.

Physiology (Bethesda, Md.)| PubMed ID: 29212888

2018
2018
Diaphragm muscle activity across respiratory motor behaviors in awake and lightly anesthetized rats.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 29357493

2018
2018
2018
Breathing: Motor Control of Diaphragm Muscle.

Physiology (Bethesda, Md.)| PubMed ID: 29412056

2018
Physiology in Perspective: Homeostasis and Survival.

Physiology (Bethesda, Md.)| PubMed ID: 29412060

2018
Phrenic motor neuron loss in aged rats.

Journal of neurophysiology| PubMed ID: 29412773

2018
2018
Physiology in Perspective: Seeking Solutions to Biological Questions.

Physiology (Bethesda, Md.)| PubMed ID: 29616879

2018
2018
2018
Physiology in Perspective: Physiology is Alive and Well.

Physiology (Bethesda, Md.)| PubMed ID: 29897301

2018
2018
Physiology in Perspective: The Breath of Life.

Physiology (Bethesda, Md.)| PubMed ID: 30109820

2018
Diaphragm muscle function following midcervical contusion injury in rats.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 30236045

2019
Physiology in Perspective: Understanding the Aging Process.

Physiology (Bethesda, Md.)| PubMed ID: 30303774

2018
2019
Phrenic motoneuron structural plasticity across models of diaphragm muscle paralysis.

The Journal of comparative neurology| PubMed ID: 30411341

2018
Hyperoxia-induced Cellular Senescence in Fetal Airway Smooth Muscle Cells.

American journal of respiratory cell and molecular biology| PubMed ID: 30508396

2019
Physiology in Perspective: Of Mice and Men.

Physiology (Bethesda, Md.)| PubMed ID: 30540230

2019
2019
Physiology in Perspective: Responding to a Changing Environment.

Physiology (Bethesda, Md.)| PubMed ID: 30724131

2019
2019
Impact of sarcopenia on diaphragm muscle fatigue.

Experimental physiology| PubMed ID: 30924589

2019
A Critical Evaluation of Current Concepts in Cerebral Palsy.

Physiology (Bethesda, Md.)| PubMed ID: 30968751

2019
Physiology in Perspective: Physiology is Everywhere.

Physiology (Bethesda, Md.)| PubMed ID: 30968752

2019
Diaphragm neuromuscular transmission failure in aged rats.

Journal of neurophysiology| PubMed ID: 31042426

2019
Physiology in Perspective: The Dilemma of Muscle Weakness.

Physiology (Bethesda, Md.)| PubMed ID: 31165686

2019
Cardiac troponin-I phosphorylation underlies myocardial contractile dysfunction induced by hypothermia rewarming.

American journal of physiology. Heart and circulatory physiology| PubMed ID: 31373512

2019
Glutamatergic input varies with phrenic motor neuron size.

Journal of neurophysiology| PubMed ID: 31389739

2019
Physiology in Perspective: Physiology Without Borders.

Physiology (Bethesda, Md.)| PubMed ID: 31389774

2019
2019
2020
2019
Aging reduces succinate dehydrogenase activity in rat type IIx/IIb diaphragm muscle fibers.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 31774353

2020
Physiology in Perspective: Complexity and Emergence of Function.

Physiology (Bethesda, Md.)| PubMed ID: 31799906

2020
Diaphragm muscle sarcopenia into very old age in mice.

Physiological reports| PubMed ID: 31908152

2020
TNFα selectively activates the IRE1α/XBP1 endoplasmic reticulum stress pathway in human airway smooth muscle cells.

American journal of physiology. Lung cellular and molecular physiology| PubMed ID: 31940218

2020
Inhibition of TrkB kinase activity impairs transdiaphragmatic pressure generation.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 31944892

2020
Endoplasmic Reticulum Stress and Mitochondrial Function in Airway Smooth Muscle.

Frontiers in cell and developmental biology| PubMed ID: 32010691

2019
Physiology in Perspective: Physiological Systems Respond to Time.

Physiology (Bethesda, Md.)| PubMed ID: 32024427

2020
Spinal cord injury and diaphragm neuromotor control.

Expert review of respiratory medicine| PubMed ID: 32077350

2020
2020
2020
Physiology in Perspective: In a World of Social Distancing.

Physiology (Bethesda, Md.)| PubMed ID: 32293233

2020
2020
Physiology in Perspective: The New Normal-Life in a Pandemic.

Physiology (Bethesda, Md.)| PubMed ID: 32490749

2020
2020
2020
2020
Diaphragm Muscle Adaptations in Health and Disease.

Drug discovery today. Disease models| PubMed ID: 32863842

2019
Extramyocellular interleukin-6 influences skeletal muscle mitochondrial physiology through canonical JAK/STAT signaling pathways.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology| PubMed ID: 32885495

2020
Physiology in Perspective: A Challenging Time.

Physiology (Bethesda, Md.)| PubMed ID: 33095687

2020
2020
TNFα induces mitochondrial fragmentation and biogenesis in human airway smooth muscle.

American journal of physiology. Lung cellular and molecular physiology| PubMed ID: 33146568

2021
Age-related impairment of autophagy in cervical motor neurons.

Experimental gerontology| PubMed ID: 33290859

2021
2021
Diaphragm neuromuscular transmission failure in a mouse model of an early-onset neuromotor disorder.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 33382958

2021
2020
Impact of congenital diaphragmatic hernia on diaphragm muscle function in neonatal rats.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 33507852

2021
Growth and survival characteristics of mice.

Animal models and experimental medicine| PubMed ID: 33532707

2020
Quantifying mitochondrial volume density in phrenic motor neurons.

Journal of neuroscience methods| PubMed ID: 33549636

2021
Improving gas exchange and exercise tolerance in mild COPD patients.

The Journal of physiology| PubMed ID: 33576012

2021
Physiology in Perspective: Harnessing Homeostasis.

Physiology (Bethesda, Md.)| PubMed ID: 33595383

2021
2021
2021
2021
Dynamic cytosolic Ca and force responses to muscarinic stimulation in airway smooth muscle.

American journal of physiology. Lung cellular and molecular physiology| PubMed ID: 33908264

2021
2021
Muscle-specific deletion of the vitamin D receptor in mice is associated with diaphragm muscle weakness.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 34013750

2021
Reflections of an Outgoing Editor-in-Chief.

Physiology (Bethesda, Md.)| PubMed ID: 34159802

2021
Physiology in Perspective: Eat, Sleep, Survive-Natural Cycle of Life.

Physiology (Bethesda, Md.)| PubMed ID: 34159806

2021
Tongue muscle contractile, fatigue, and fiber type properties in rats.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 34323593

2021
2021
Mitochondrial morphology and function varies across diaphragm muscle fiber types.

Respiratory physiology & neurobiology| PubMed ID: 34478909

2022
2021
2021
Physiological Impact of Hypothermia: The Good, the Bad, and the Ugly.

Physiology (Bethesda, Md.)| PubMed ID: 34632808

2022
2021
2021
2021
Automated evaluation of respiratory signals to provide insight into respiratory drive.

Respiratory physiology & neurobiology| PubMed ID: 35218924

2022
2022
2022
2022
2022
Diaphragm muscle function in a mouse model of early-onset spasticity.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 35608200

2022
Primary cilia in satellite cells are the mechanical sensors for muscle hypertrophy.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 35671424

2022
Mitochondrial adaptations to inactivity in diaphragm muscle fibers.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 35678745

2022
2022
Structure and Function of the Mammalian Neuromuscular Junction.

Comprehensive Physiology| PubMed ID: 35950651

2022
2022
2022
2023
2023
2023
2023
2023
2023
Size-dependent differences in mitochondrial volume density in phrenic motor neurons.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 37022966

2023
2023
Cell-Based Measurement of Mitochondrial Function in Human Airway Smooth Muscle Cells.

International journal of molecular sciences| PubMed ID: 37511264

2023
2020
Chloroquine impairs maximal transdiaphragmatic pressure generation in old mice.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 37823202

2023
Sarcopenia of the longitudinal tongue muscles in rats.

Respiratory physiology & neurobiology| PubMed ID: 37863156

2024
2023
2023
Molecular mechanisms underlying TNFα-induced mitochondrial fragmentation in human airway smooth muscle cells.

American journal of physiology. Lung cellular and molecular physiology| PubMed ID: 38084427

2024
2024
Postnatal survival of phrenic motor neurons is promoted by BDNF/TrkB.FL signaling.

Journal of applied physiology (Bethesda, Md. : 1985)| PubMed ID: 38511211

2024
2024
2024
2024