David Brown

Institute of Biochemical Chemistry, Heriot-Watt University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2024

Other Publications

Article	Year
Investigating the relationship between nanomaterial hazard and physicochemical properties: Informing the exploitation of nanomaterials within therapeutic and diagnostic applications. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 22940205	2012
The role of Kupffer cells in the hepatic response to silver nanoparticles. Nanotoxicology\| PubMed ID: 24344730	2014
Serum enhanced cytokine responses of macrophages to silica and iron oxide particles and nanomaterials: a comparison of serum to lung lining fluid and albumin dispersions. Journal of applied toxicology : JAT\| PubMed ID: 24737200	2014
Mechanism of neutrophil activation and toxicity elicited by engineered nanomaterials. Toxicology in vitro : an international journal published in association with BIBRA\| PubMed ID: 25962642	2015
Multi-walled carbon nanotube induced frustrated phagocytosis, cytotoxicity and pro-inflammatory conditions in macrophages are length dependent and greater than that of asbestos. Toxicology in vitro : an international journal published in association with BIBRA\| PubMed ID: 26086123	2015
Exploring the cellular and tissue uptake of nanomaterials in a range of biological samples using multimodal nonlinear optical microscopy. Nanotechnology\| PubMed ID: 26584818	2015
Organ burden and pulmonary toxicity of nano-sized copper (II) oxide particles after short-term inhalation exposure. Nanotoxicology\| PubMed ID: 27132941	2016
Surfactants from itaconic acid: Toxicity to HaCaT keratinocytes in vitro, micellar solubilization, and skin permeation enhancement of hydrocortisone. International journal of pharmaceutics\| PubMed ID: 28356226	2017
A Flow Cytometry-based Method for the Screening of Nanomaterial-induced Reactive Oxygen Species Production in Leukocytes Subpopulations in Whole Blood. Basic & clinical pharmacology & toxicology\| PubMed ID: 28691406	2018
The effect of aluminium and sodium impurities on the in vitro toxicity and pro-inflammatory potential of cristobalite. Environmental research\| PubMed ID: 28802207	2017
Impact of copper oxide nanomaterials on differentiated and undifferentiated Caco-2 intestinal epithelial cells; assessment of cytotoxicity, barrier integrity, cytokine production and nanomat... Particle and fibre toxicology\| PubMed ID: 28835236	2017
Transcriptional profiling reveals gene expression changes associated with inflammation and cell proliferation following short-term inhalation exposure to copper oxide nanoparticles. Journal of applied toxicology : JAT\| PubMed ID: 29094763	2018
Adoption of in vitro systems and zebrafish embryos as alternative models for reducing rodent use in assessments of immunological and oxidative stress responses to nanomaterials. Critical reviews in toxicology\| PubMed ID: 29239234	2018
Corrigendum to "the role of intracellular redox imbalance in nanomaterial induced cellular damage and genotoxicity: A review". Environmental and molecular mutagenesis\| PubMed ID: 29423917	2018
Assessing the bioactivity of crystalline silica in heated high-temperature insulation wools. Inhalation toxicology\| PubMed ID: 30328741	2018
The influence of organic modification on the cytotoxicity of clay particles to keratinocytes, hepatocytes and macrophages; an investigation towards the safe use of polymer-clay nanocomposite... Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association\| PubMed ID: 30797875	2019
The importance of inter-individual Kupffer cell variability in the governance of hepatic toxicity in a 3D primary human liver microtissue model. Scientific reports\| PubMed ID: 31086251	2019
Using 3D gastrointestinal tract in vitro models with microfold cells and mucus secreting ability to assess the hazard of copper oxide nanomaterials. Journal of nanobiotechnology\| PubMed ID: 31113462	2019
The mechanism-based toxicity screening of particles with use in the food and nutrition sector via the ToxTracker reporter system. Toxicology in vitro : an international journal published in association with BIBRA\| PubMed ID: 31279906	2019
The variances in cytokine production profiles from non- or activated THP-1, Kupffer cell and human blood derived primary macrophages following exposure to either alcohol or a panel of engine... PloS one\| PubMed ID: 31393970	2019
Importance of Surface Coating to Accumulation Dynamics and Acute Toxicity of Copper Nanomaterials and Dissolved Copper in Daphnia magna. Environmental toxicology and chemistry\| PubMed ID: 31610609	2020
Use of EpiAlveolar Lung Model to Predict Fibrotic Potential of Multiwalled Carbon Nanotubes. ACS nano\| PubMed ID: 32167743	2020
Neutrophil activation by nanomaterials : comparing strengths and limitations of primary human cells with those of an immortalized (HL-60) cell line. Nanotoxicology\| PubMed ID: 33272088	2021
Time dependent impact of copper oxide nanomaterials on the expression of genes associated with oxidative stress, metal binding, inflammation and mucus secretion in single and co-culture inte... Toxicology in vitro : an international journal published in association with BIBRA\| PubMed ID: 33839236	2021
An in vitro assessment of the toxicity of two-dimensional synthetic and natural layered silicates. Toxicology in vitro : an international journal published in association with BIBRA\| PubMed ID: 34801683	2022
Acute hazard assessment of silver nanoparticles following intratracheal instillation, oral and intravenous injection exposures. Nanotoxicology\| PubMed ID: 35015612	2021
Transgenic zebrafish larvae as a non-rodent alternative model to assess pro-inflammatory (neutrophil) responses to nanomaterials. Nanotoxicology\| PubMed ID: 35797989	2022
Comparison of In Vitro Approaches to Assess the Antibacterial Effects of Nanomaterials. Journal of functional biomaterials\| PubMed ID: 36412895	2022