Hefeng Huang

Obstetrics and Gynecology Hospital, Fudan University

Affiliated withFudan University Zhejiang University School of Medicine Chinese Academy of Medical Sciences (No. 2019RU056)

Research Area

Medicine

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2024

Other Publications

Article	Year
Methylation levels at IGF2 and GNAS DMRs in infants born to preeclamptic pregnancies. BMC genomics\| PubMed ID: 23844573	2013
Reduced fetal telomere length in gestational diabetes. PloS one\| PubMed ID: 24465936	2014
Alteration in methylation level at 11β-hydroxysteroid dehydrogenase type 2 gene promoter in infants born to preeclamptic women. BMC genetics\| PubMed ID: 25200528	2014
Increased methylation at differentially methylated region of GNAS in infants born to gestational diabetes. BMC medical genetics\| PubMed ID: 25269528	2014
Enhancing the precision of genetic lineage tracing using dual recombinases. Nature medicine\| PubMed ID: 29131159	2017
Basonuclin 1 deficiency is a cause of primary ovarian insufficiency. Human molecular genetics\| PubMed ID: 30010909	2018
Early-life undernutrition reprograms CD4 T-cell glycolysis and epigenetics to facilitate asthma. The Journal of allergy and clinical immunology\| PubMed ID: 30654047	2019
Dietary restriction and/or exercise training impairs spermatogenesis in normal rats. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme\| PubMed ID: 32905708	2021
Maternal high-fat-diet exposure is associated with elevated blood pressure and sustained increased leptin levels through epigenetic memory in offspring. Scientific reports\| PubMed ID: 33431976	2021
Elevated ovarian pentraxin 3 in polycystic ovary syndrome. Journal of assisted reproduction and genetics\| PubMed ID: 33594624	2021
Abnormal Glucose Metabolism in Male Mice Offspring Conceived by Fertilization and Frozen-Thawed Embryo Transfer. Frontiers in cell and developmental biology\| PubMed ID: 33634140	2021
Effects of acute ambient pollution exposure on preterm prelabor rupture of membranes: A time-series analysis in Shanghai, China. Environmental pollution (Barking, Essex : 1987)\| PubMed ID: 33662814	2021
Alternations of cesarean section rates in a non-infected population after the outbreak of COVID-19: a cross-sectional study. Psychology, health & medicine\| PubMed ID: 33715523	2022
Study protocol for the Sino-Canadian Healthy Life Trajectories Initiative (SCHeLTI): a multicentre, cluster-randomised, parallel-group, superiority trial of a multifaceted community-family-m... BMJ open\| PubMed ID: 33795307	2021
Paternal obesity impairs hepatic gluconeogenesis of offspring by altering Igf2/H19 DNA methylation. Molecular and cellular endocrinology\| PubMed ID: 33811969	2021
Caregivers' perceptions, challenges and service needs related to tackling childhood overweight and obesity: a qualitative study in three districts of Shanghai, China. BMC public health\| PubMed ID: 33882878	2021
Perinatal outcomes of neonates born from different endometrial preparation protocols after frozen embryo transfer: a retrospective cohort study. BMC pregnancy and childbirth\| PubMed ID: 33926401	2021
Effect of embryo cryopreservation duration on pregnancy-related complications and birthweight after frozen-thawed embryo transfer: a retrospective cohort study. Journal of developmental origins of health and disease\| PubMed ID: 33947503	2022
Gestational high-fat diet impaired demethylation of Pparα and induced obesity of offspring. Journal of cellular and molecular medicine\| PubMed ID: 33955677	2021
Association of homocysteine with IVF/ICSI outcomes stratified by MTHFR C677T polymorphisms: a prospective cohort study. Reproductive biomedicine online\| PubMed ID: 34016520	2021
Expanding the Scope of Non-invasive Prenatal Testing to Detect Fetal Chromosomal Copy Number Variations. Frontiers in molecular biosciences\| PubMed ID: 34055879	2021
Neurogenesis Potential Evaluation and Transcriptome Analysis of Fetal Hypothalamic Neural Stem/Progenitor Cells With Prenatal High Estradiol Exposure. Frontiers in genetics\| PubMed ID: 34239542	2021
Low-level germline mosaicism of a novel SMARCA2 missense variant: Expanding the phenotypic spectrum and mode of genetic transmission. Molecular genetics & genomic medicine\| PubMed ID: 34296532	2021
Comparison of Genome-Wide DNA Methylation Profiles of Human Fetal Tissues Conceived by Fertilization and Natural Conception. Frontiers in cell and developmental biology\| PubMed ID: 34336842	2021
Association Between Paternal Age and Birth Weight in Preterm and Full-Term Birth: A Retrospective Study. Frontiers in endocrinology\| PubMed ID: 34367073	2021
Adverse Maternal and Neonatal Outcomes in Women With Elevated Intrapartum Temperature Complicated by Histological Chorioamnionitis at Term: A Propensity-Score Matched Study. Frontiers in pediatrics\| PubMed ID: 34368025	2021
Anti-Müllerian Hormone Accelerates Pathological Process of Insulin Resistance in Polycystic Ovary Syndrome Patients. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme\| PubMed ID: 34384107	2021
Intrauterine hyperglycemia impairs memory across two generations. Translational psychiatry\| PubMed ID: 34417446	2021
Effect of an individualised nutritional intervention on gestational diabetes mellitus prevention in a high-risk population screened by a prediction model: study protocol for a multicentre ra... BMC pregnancy and childbirth\| PubMed ID: 34429102	2021
Comprehensive non-invasive prenatal screening for pregnancies with elevated risks of genetic disorders: protocol for a prospective, multicentre study. BMJ open\| PubMed ID: 34452972	2021
Different Strategies of Preimplantation Genetic Testing for Aneuploidies in Women of Advanced Maternal Age: A Systematic Review and Meta-Analysis. Journal of clinical medicine\| PubMed ID: 34501345	2021
Intrauterine Hyperglycemia Alters the Metabolomic Profile in Fetal Mouse Pancreas in a Gender-Specific Manner. Frontiers in endocrinology\| PubMed ID: 34531826	2021
Anxiety and depression-like behaviours are more frequent in aged male mice conceived by ART compared with natural conception. Reproduction (Cambridge, England)\| PubMed ID: 34605773	2021
COVID-19 Lockdown Increased the Risk of Preterm Birth. Frontiers in medicine\| PubMed ID: 34646839	2021
The Impact of Gestational Weight Gain on the Risks of Adverse Maternal and Infant Outcomes among Normal BMI Women with High Triglyceride Levels during Early Pregnancy. Nutrients\| PubMed ID: 34684457	2021
Optogenetic Activation of Arcuate Kisspeptin Neurons Generates a Luteinizing Hormone Surge-Like Secretion in an Estradiol-Dependent Manner. Frontiers in endocrinology\| PubMed ID: 34795643	2021
Classification and Interpretation for 11 FBN1 Variants Responsible for Marfan Syndrome and Pre-implantation Genetic Testing (PGT) for Two Families Successfully Blocked Transmission of the Pa... Frontiers in molecular biosciences\| PubMed ID: 34957211	2021
Circulating Innate Lymphoid Cells Exhibit Distinctive Distribution During Normal Pregnancy. Reproductive sciences (Thousand Oaks, Calif.)\| PubMed ID: 34988918	2022
Association between prenatal exposure to ambient air pollutants and postpartum depressive symptoms: A multi-city cohort study. Environmental research\| PubMed ID: 35077713	2022
Advanced paternal age increased metabolic risks in mice offspring. Biochimica et biophysica acta. Molecular basis of disease\| PubMed ID: 35131436	2022
Associations of PM exposure with blood glucose impairment in early pregnancy and gestational diabetes mellitus. Ecotoxicology and environmental safety\| PubMed ID: 35131583	2022
HSD17B12 dosage insufficiency induced premature ovarian insufficiency in humans and mice. Clinical and translational medicine\| PubMed ID: 35187845	2022
Integrated Multi-Omics Analysis Reveals the Effect of Maternal Gestational Diabetes on Fetal Mouse Hippocampi. Frontiers in cell and developmental biology\| PubMed ID: 35237591	2022
Environmental epigenetic interaction of gametes and early embryos†. Biology of reproduction\| PubMed ID: 35323884	2022
Effects of Paternal Obesity on Fetal Development and Pregnancy Complications: A Prospective Clinical Cohort Study. Frontiers in endocrinology\| PubMed ID: 35360083	2022
Association between paternal age and subtypes of preterm birth: a retrospective study. Reproductive biomedicine online\| PubMed ID: 35400578	2022
Maternal inheritance of glucose intolerance via oocyte TET3 insufficiency. Nature\| PubMed ID: 35585240	2022
Exposure to Chloramine and Chloroform in Tap Water and Adverse Perinatal Outcomes in Shanghai. International journal of environmental research and public health\| PubMed ID: 35682093	2022
Maternal High-Fat Diet Aggravates Allergic Asthma in Offspring via Modulating CD4 T-Cell Differentiation. Nutrients\| PubMed ID: 35745240	2022
Diabetes predisposition inherited through maternal germline. Clinical and translational medicine\| PubMed ID: 35802824	2022
Preimplantation genetic testing for aneuploidy in severe male factor infertility: protocol for a multicenter randomised controlled trial. BMJ open\| PubMed ID: 35831058	2022
Associations Between Asthma and Polycystic Ovary Syndrome: Current Perspectives. Frontiers in endocrinology\| PubMed ID: 35865312	2022
Lysophosphatidic Acid Improves Human Sperm Motility by Enhancing Glycolysis and Activating L-Type Calcium Channels. Frontiers in endocrinology\| PubMed ID: 35903269	2022
Tracking of menstrual cycles and prediction of the fertile window via measurements of basal body temperature and heart rate as well as machine-learning algorithms. Reproductive biology and endocrinology : RB&E\| PubMed ID: 35964035	2022
Effect of Maternal Glucose and Triglyceride Levels during Early Pregnancy on Pregnancy Outcomes: A Retrospective Cohort Study. Nutrients\| PubMed ID: 36014801	2022
Interactive effects of ambient air pollution and sunshine duration on the risk of intrahepatic cholestasis of pregnancy. Environmental research\| PubMed ID: 36116502	2022
Internet-based cognitive therapy for women with antenatal depressive symptoms during the COVID-19 pandemic: protocol for a multi-center randomized controlled trial across China. Trials\| PubMed ID: 36131289	2022
Living birth following preimplantation genetic testing for monogenic disorders to prevent low-level germline mosaicism related Nicolaides-Baraitser syndrome. Frontiers in genetics\| PubMed ID: 36160002	2022
LncRNA THOR promotes endometrial cancer progression through the AKT and ERK signaling pathways. Medical oncology (Northwood, London, England)\| PubMed ID: 36175594	2022
Maternal lipid profile during early pregnancy and birth weight: A retrospective study. Frontiers in endocrinology\| PubMed ID: 36187100	2022
Genetic deconvolution of fetal and maternal cell-free DNA in maternal plasma enables next-generation non-invasive prenatal screening. Cell discovery\| PubMed ID: 36229437	2022
Editorial: Polycystic ovary syndrome (PCOS): Mechanism and management. Frontiers in endocrinology\| PubMed ID: 36277701	2022
Breastfeeding Practices and Associated Factors in Shanghai: A Cross-Sectional Study. Nutrients\| PubMed ID: 36297120	2022
The lncRNA THOR interacts with and stabilizes hnRNPD to promote cell proliferation and metastasis in breast cancer. Oncogene\| PubMed ID: 36329124	2022
Construction of a ceRNA network in polycystic ovary syndrome (PCOS) driven by exosomal lncRNA. Frontiers in genetics\| PubMed ID: 36406137	2022
Associations between short-term and long-term exposure to particulate matter and preterm birth. Chemosphere\| PubMed ID: 36455656	2023
Association of maternal triglyceride responses to thyroid function in early pregnancy with gestational diabetes mellitus. Frontiers in endocrinology\| PubMed ID: 36518243	2022
Small RNA perspective of physical exercise-related improvement of male reproductive dysfunction due to obesity. Frontiers in endocrinology\| PubMed ID: 36531465	2022
The epigenetic mechanisms underlying gamete origin of adult-onset diseases. Science bulletin\| PubMed ID: 36546054	2022
Effects of parental overweight and obesity on offspring's mental health: A meta-analysis of observational studies. PloS one\| PubMed ID: 36548252	2022
A PPARG Splice Variant in Granulosa Cells Is Associated with Polycystic Ovary Syndrome. Journal of clinical medicine\| PubMed ID: 36555903	2022
Association between Plasma Trace Element Concentrations in Early Pregnancy and Gestational Diabetes Mellitus in Shanghai, China. Nutrients\| PubMed ID: 36615774	2022
Parental mosaicism detection and preimplantation genetic testing in families with multiple transmissions of de novo mutations. Journal of medical genetics\| PubMed ID: 36707240	2023
Characteristics and possible mechanisms of metabolic disorder in overweight women with polycystic ovary syndrome. Frontiers in endocrinology\| PubMed ID: 36714563	2022
Delivery and neonatal outcomes of pregnant women during the Shanghai lockdown: A retrospective analysis. Frontiers in pediatrics\| PubMed ID: 36816385	2023
Preimplantation Genetic Testing (PGT) and Prenatal Diagnosis of Schaaf-Yang Syndrome: A Report of Three Families and a Research on Genotype-Phenotype Correlations. Journal of clinical medicine\| PubMed ID: 36836222	2023
Comparative effectiveness of transvaginal repair vs. hysteroscopic resection in patients with symptomatic uterine niche. Frontiers in surgery\| PubMed ID: 36843994	2023
An intergenerational life-course approach to address early childhood obesity and adiposity: the Healthy Life Trajectories Initiative (HeLTI). The Lancet. Global health\| PubMed ID: 36866472	2023
Serum anti-Müllerian hormone levels are associated with perinatal outcomes in women undergoing IVF/ICSI: A multicenter retrospective cohort study. Frontiers in endocrinology\| PubMed ID: 36896183	2023
Effects of Particulate Matter on the Risk of Gestational Hypertensive Disorders and Their Progression. Environmental science & technology\| PubMed ID: 36913485	2023
Effect of Frozen-Thawed Embryo Transfer on the Metabolism of Children in Early Childhood. Journal of clinical medicine\| PubMed ID: 36983323	2023
Mixed exposure effect of seminal metals on semen quality, mediation of total antioxidant capacity, and moderation of GSTM1/GSTT1 gene deletion in Chinese reproductive-aged men. Environmental research\| PubMed ID: 37054833	2023
The causal association between smoking initiation, alcohol and coffee consumption, and women's reproductive health: A two-sample Mendelian randomization analysis. Frontiers in genetics\| PubMed ID: 37091804	2023
Sperm morphological abnormalities in autosomal dominant polycystic kidney disease are associated with the Hippo signaling pathway via PC1. Frontiers in endocrinology\| PubMed ID: 37152951	2023
Developmental origins of diabetes mellitus: Environmental epigenomics and emerging patterns. Journal of diabetes\| PubMed ID: 37190864	2023
Biallelic variants in RBM42 cause a multisystem disorder with neurological, facial, cardiac, and musculoskeletal involvement. Protein & cell\| PubMed ID: 37294900	2024
The Influences of Perinatal Androgenic Exposure on Cardiovascular and Metabolic Disease of Offspring of PCOS. Reproductive sciences (Thousand Oaks, Calif.)\| PubMed ID: 37380913	2023
Machine learning and bioinformatics framework integration reveal potential characteristic genes related to immune cell infiltration in preeclampsia. Frontiers in physiology\| PubMed ID: 37389124	2023
Elevated follicular cortisone level is a negative predictor of clinical pregnancy in women undergoing fresh embryo transfer. Heliyon\| PubMed ID: 37415947	2023
Carrier burden of over 300 diseases in Han Chinese identified by expanded carrier testing of 300 couples using assisted reproductive technology. Journal of assisted reproduction and genetics\| PubMed ID: 37450097	2023
Fetal weight estimation based on deep neural network: a retrospective observational study. BMC pregnancy and childbirth\| PubMed ID: 37533038	2023
Research Progress of Maternal Metabolism on Cardiac Development and Function in Offspring. Nutrients\| PubMed ID: 37571325	2023
Rare loss-of-function variants reveal threshold and multifactorial inheritance of dextrocardia. Science bulletin\| PubMed ID: 37573248	2023
Editorial: Polycystic ovary syndrome: mechanism and management-volume II. Frontiers in endocrinology\| PubMed ID: 37588987	2023
Noninvasive Evaluation of Fetal Zygosity in Twin Pregnancies Involving a Binary Analysis of Single-Nucleotide Polymorphisms. The Journal of molecular diagnostics : JMD\| PubMed ID: 37599029	2023
Overexpression of Pde4d in rat granulosa cells inhibits maturation and atresia of antral follicles to induce polycystic ovary. Biochimica et biophysica acta. Molecular basis of disease\| PubMed ID: 37673361	2024
Developmental origins of adult diseases. Medical review (Berlin, Germany)\| PubMed ID: 37724166	2022
Recurrent human 16p11.2 microdeletions in type I Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome patients in Chinese Han population. Molecular genetics & genomic medicine\| PubMed ID: 37789575	2024
NLRP3 Inflammasome-dependent Pathway is Involved in the Pathogenesis of Polycystic Ovary Syndrome. Reproductive sciences (Thousand Oaks, Calif.)\| PubMed ID: 37815748	2024
Early characterisation and prediction of liver diseases in pregnancy by plasma cell-free RNAs. Clinical and translational medicine\| PubMed ID: 37830149	2023
Follicle-stimulating hormone orchestrates glucose-stimulated insulin secretion of pancreatic islets. Nature communications\| PubMed ID: 37914684	2023
Assisted reproductive technology and imprinting errors: analyzing underlying mechanisms from epigenetic regulation. Human fertility (Cambridge, England)\| PubMed ID: 37929309	2023
Polycystic Ovary Syndrome Fuels Cardiovascular Inflammation and Aggravates Ischemic Cardiac Injury. Circulation\| PubMed ID: 37937441	2023
Chinese experts' consensus guideline on preimplantation genetic testing of monogenic disorders. Human reproduction (Oxford, England)\| PubMed ID: 37982416	2023
Research Progress on the effects of adverse exposure during pregnancy on skeletal muscle function in offspring. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences\| PubMed ID: 37986679	2023
Research progress and challenges of preimplantation genetic testing for polygenic diseases. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences\| PubMed ID: 37987034	2023
Prediction of shared gene signatures and biological mechanisms between polycystic ovary syndrome and asthma: Based on weighted gene coexpression network analysis. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics\| PubMed ID: 38055328	2024
Metabolome implies increased fatty acid utilization and histone methylation in the follicles from hyperandrogenic PCOS women. The Journal of nutritional biochemistry\| PubMed ID: 38104867	2024
Sexual behavior and cardiovascular diseases: univariable and multivariable Mendelian randomization. Frontiers in cardiovascular medicine\| PubMed ID: 38116537	2023
Effect of transvaginal Lactobacillus supplementation on reversing lower genital tract dysbiosis and improving perinatal outcomes in PCOS patients after IVF-FET: a study protocol for a multic... Trials\| PubMed ID: 38129882	2023
Long-term health risk of offspring born from assisted reproductive technologies. Journal of assisted reproduction and genetics\| PubMed ID: 38146031	2024
Prospective prenatal cell-free DNA screening for genetic conditions of heterogenous etiologies. Nature medicine\| PubMed ID: 38253798	2024
Cardiovascular health of offspring conceived by assisted reproduction technology: a comprehensive review. Frontiers in cardiovascular medicine\| PubMed ID: 38292241	2024
LncRNA SNHG5 adversely governs follicular growth in PCOS via miR-92a-3p/CDKN1C axis. iScience\| PubMed ID: 38313057	2024
Practice guideline on ovarian tissue cryopreservation and transplantation in the prevention and treatment of iatrogenic premature ovarian insufficiency. Maturitas\| PubMed ID: 38325136	2024
A mutual comparison of pregnancy outcomes between different conception modes: a propensity score matching based retrospective cohort study. Frontiers in endocrinology\| PubMed ID: 38332889	2024
A morphological study of symptomatic uterine niche using three-dimensional models from thin-slice magnetic resonance imaging. Reproductive biomedicine online\| PubMed ID: 38340538	2024
Association of serum folic acid levels in response to fasting blood glucose in early pregnancy with the risk of gestational diabetes mellitus: A retrospective cohort study. Nutrition (Burbank, Los Angeles County, Calif.)\| PubMed ID: 38422754	2024
A novel preimplantation genetic testing strategy for a subtelomeric genetic disorder: A case study. Genes & diseases\| PubMed ID: 38425427	2024
Sex-Specific Alterations in Placental Proteomics Induced by Intrauterine Hyperglycemia. Journal of proteome research\| PubMed ID: 38470452	2024
Reduction in Placental Metal and Metalloid in Preeclampsia: A Case-Control Study. Nutrients\| PubMed ID: 38542681	2024
The impact of maternal age on aneuploidy in oocytes: Reproductive consequences, molecular mechanisms, and future directions. Ageing research reviews\| PubMed ID: 38582380	2024
FSH regulates glucose-stimulated insulin secretion: A bell-shaped curve effect. Journal of diabetes\| PubMed ID: 38599851	2024
Pre-eclamptic foetal programming predisposes offspring to hepatic steatosis via DNA methylation. Biochimica et biophysica acta. Molecular basis of disease\| PubMed ID: 38648899	2024
Characterization of a novel adipose tissue located between abdominal lymph nodes and cervix/prostate in mice. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 38747899	2024
Intrauterine hyperglycemia induces SIRT3-mediated mitochondrial dysfunction: the fetal origin pathogenesis of precocious osteoarthritis. Osteoarthritis and cartilage\| PubMed ID: 38782252	2024
Cerium Oxide Nanozymes Improve Skeletal Muscle Function in Gestational Diabetic Offspring by Attenuating Mitochondrial Oxidative Stress. ACS omega\| PubMed ID: 38799328	2024
Deamidation enables pathogenic SMAD6 variants to activate the BMP signaling pathway. Science China. Life sciences\| PubMed ID: 38913236	2024
Effects of exposure to multiple metallic elements in the first trimester of pregnancy on the risk of preterm birth. Maternal & child nutrition\| PubMed ID: 38925571	2024
[Reproductive Health-Oriented Development in Assisted Reproductive Technologies]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition\| PubMed ID: 38948299	2024