Yousuke Takahama

Thymus Biology Section, National Institutes of Health

Affiliated withNational Institutes of Health

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2024

Other Publications

Article	Year
Defective brain development in mice lacking the Hif-1alpha gene in neural cells. Molecular and cellular biology\| PubMed ID: 12972594	2003
Role of hypoxia-inducible factor 1alpha in T cells as a negative regulator in development of vascular remodeling. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 20007912	2010
TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24324158	2013
Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24337745	2014
TCR affinity for thymoproteasome-dependent positively selecting peptides conditions antigen responsiveness in CD8(+) T cells. Nature immunology\| PubMed ID: 26301566	2015
The immunoproteasome and thymoproteasome: functions, evolution and human disease. Nature immunology\| PubMed ID: 30104634	2018
Thymoproteasome and peptidic self. Immunogenetics\| PubMed ID: 30324237	2019
A Distinct Subset of Fibroblastic Stromal Cells Constitutes the Cortex-Medulla Boundary Subcompartment of the Lymph Node. Frontiers in immunology\| PubMed ID: 30333825	2018
Thymus machinery for T-cell selection. International immunology\| PubMed ID: 30476234	2019
Biology, evolution, and history of antigen processing and presentation: Immunogenetics special issue 2019. Immunogenetics\| PubMed ID: 30706092	2019
TCR Affinity for In Vivo Peptide-Induced Thymic Positive Selection Fine-Tunes TCR Responsiveness of Peripheral CD8 T Cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 31235550	2019
Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of in Thymic Epithelial Cells. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 31243087	2019
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition). European journal of immunology\| PubMed ID: 31633216	2019
Trans-omics Impact of Thymoproteasome in Cortical Thymic Epithelial Cells. Cell reports\| PubMed ID: 31775054	2019
Myc controls a distinct transcriptional program in fetal thymic epithelial cells that determines thymus growth. Nature communications\| PubMed ID: 31792212	2019
PITHD1 is a proteasome-interacting protein essential for male fertilization. The Journal of biological chemistry\| PubMed ID: 31915251	2020
Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells. Nature communications\| PubMed ID: 32366944	2020
Postnatal Involution and Counter-Involution of the Thymus. Frontiers in immunology\| PubMed ID: 32477366	2020
Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt1. iScience\| PubMed ID: 32585597	2020
The thymoproteasome hardwires the TCR repertoire of CD8+ T cells in the cortex independent of negative selection. The Journal of experimental medicine\| PubMed ID: 33555295	2021
Medullary stromal cells synergize their production and capture of CCL21 for T-cell emigration from neonatal mouse thymus. Blood advances\| PubMed ID: 33570638	2021
Thymoproteasome optimizes positive selection of CD8 T cells without contribution of negative selection. Advances in immunology\| PubMed ID: 33993918	2021
Specific impact of β5t on proteasome subunit composition in cortical thymic epithelial cells. Cell reports\| PubMed ID: 34496235	2021
Peptides for T cell selection in the thymus. Peptides\| PubMed ID: 34624431	2021
mTEC damage risks immune recovery. The Journal of experimental medicine\| PubMed ID: 34919145	2022
Fine-tuning of β-catenin in mouse thymic epithelial cells is required for postnatal T-cell development. eLife\| PubMed ID: 35042581	2022
Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift. Nature communications\| PubMed ID: 35513371	2022
Tissue-specific proteasomes in generation of MHC class I peptides and CD8 T cells. Current opinion in immunology\| PubMed ID: 35689940	2022
Large-Scale Isolation of Mouse Thymic Epithelial Cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 36374458	2023
The thymoproteasome in shaping the CD8 T-cell repertoire. Current opinion in immunology\| PubMed ID: 37210932	2023
Endogenous CCL21-Ser deficiency reduces B16-F10 melanoma growth by enhanced antitumor immunity. Heliyon\| PubMed ID: 37664721	2023
Developmental conversion of thymocyte-attracting cells into self-antigen-displaying cells in embryonic thymus medulla epithelium. bioRxiv : the preprint server for biology\| PubMed ID: 37873155	2023
Developmental conversion of thymocyte-attracting cells into self-antigen-displaying cells in embryonic thymus medulla epithelium. eLife\| PubMed ID: 38466627	2024
Functionally diverse thymic medullary epithelial cells interplay to direct central tolerance. Cell reports\| PubMed ID: 38581680	2024
Generation and repair of thymic epithelial cells. The Journal of experimental medicine\| PubMed ID: 38980292	2024