Karen S. Sfanos

Department of Pathology, Johns Hopkins University School of Medicine

Affiliated withJohns Hopkins University School of Medicine Sidney Kimmel Comprehensive Cancer Center

Research Area

Biography

Karen S. Sfanos has not added Biography.
If you are Karen S. Sfanos and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 6	2024

Other Publications

Article	Year
Acute inflammatory proteins constitute the organic matrix of prostatic corpora amylacea and calculi in men with prostate cancer. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19202053	2009
Human prostate-infiltrating CD8+ T lymphocytes are oligoclonal and PD-1+. The Prostate\| PubMed ID: 19670224	2009
The "infectious" nature of human prostate cancer: a cautionary note. Oncotarget\| PubMed ID: 21521904	2011
Identification of replication competent murine gammaretroviruses in commonly used prostate cancer cell lines. PloS one\| PubMed ID: 21698104	2011
Prostate cancer and inflammation: the evidence. Histopathology\| PubMed ID: 22212087	2012
XMRV and prostate cancer--a 'final' perspective. Nature reviews. Urology\| PubMed ID: 22231291	2012
Multilocus sequence typing (MLST) analysis of Propionibacterium acnes isolates from radical prostatectomy specimens. The Prostate\| PubMed ID: 23184509	2013
A mouse model of chronic prostatic inflammation using a human prostate cancer-derived isolate of Propionibacterium acnes. The Prostate\| PubMed ID: 23389852	2013
Infection of Xenotransplanted Human Cell Lines by Murine Retroviruses: A Lesson Brought Back to Light by XMRV. Frontiers in oncology\| PubMed ID: 23785669	2013
Deciphering the intracellular fate of Propionibacterium acnes in macrophages. BioMed research international\| PubMed ID: 23862148	2013
Comparative genomics reveals distinct host-interacting traits of three major human-associated propionibacteria. BMC genomics\| PubMed ID: 24053623	2013
Biobanking of derivatives from radical retropubic and robot-assisted laparoscopic prostatectomy tissues as part of the prostate cancer biorepository network. The Prostate\| PubMed ID: 24115205	2014
Draft Genome Sequences of Two Strains of Propionibacterium acnes Isolated from Radical Prostatectomy Specimens. Genome announcements\| PubMed ID: 24356837	2013
The role of inflammation in prostate cancer. Advances in experimental medicine and biology\| PubMed ID: 24818723	2014
Infections and inflammation in prostate cancer. American journal of clinical and experimental urology\| PubMed ID: 25110720	2013
Bacterial Prostatitis Enhances 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine (PhIP)-Induced Cancer at Multiple Sites. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 25990088	2015
A Paracrine Role for IL6 in Prostate Cancer Patients: Lack of Production by Primary or Metastatic Tumor Cells. Cancer immunology research\| PubMed ID: 26048576	2015
Low Intratumoral Mast Cells Are Associated With a Higher Risk of Prostate Cancer Recurrence. The Prostate\| PubMed ID: 27868214	2017
Profiling the Urinary Microbiome in Men with Positive versus Negative Biopsies for Prostate Cancer. The Journal of urology\| PubMed ID: 28797714	2018
The inflammatory microenvironment and microbiome in prostate cancer development. Nature reviews. Urology\| PubMed ID: 29089606	2018
Rapid Loss of RNA Detection by In Situ Hybridization in Stored Tissue Blocks and Preservation by Cold Storage of Unstained Slides. American journal of clinical pathology\| PubMed ID: 29106457	2017
Targeting Toll-like Receptors in Cancer Prevention. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 29661854	2018
The microbiome in prostate inflammation and prostate cancer. Prostate cancer and prostatic diseases\| PubMed ID: 29795140	2018
Association of tumor-infiltrating T-cell density with molecular subtype, racial ancestry and clinical outcomes in prostate cancer. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc\| PubMed ID: 29849114	2018
Compositional differences in gastrointestinal microbiota in prostate cancer patients treated with androgen axis-targeted therapies. Prostate cancer and prostatic diseases\| PubMed ID: 29988102	2018
Corpora amylacea in prostatectomy tissue and associations with molecular, histological, and lifestyle factors. The Prostate\| PubMed ID: 30009541	2018
Molecular Pathology of High-Grade Prostatic Intraepithelial Neoplasia: Challenges and Opportunities. Cold Spring Harbor perspectives in medicine\| PubMed ID: 30082453	2019
A role for paracrine interleukin-6 signaling in the tumor microenvironment in prostate tumor growth. The Prostate\| PubMed ID: 30345534	2019
The Microbiome and Genitourinary Cancer: A Collaborative Review. European urology\| PubMed ID: 30655087	2019
IBD as a risk factor for prostate cancer: what is the link? Nature reviews. Urology\| PubMed ID: 30742047	2019
If this is true, what does it imply? How end-user antibody validation facilitates insights into biology and disease. Asian journal of urology\| PubMed ID: 30775245	2019
TP53 missense mutation is associated with increased tumor-infiltrating T cells in primary prostate cancer. Human pathology\| PubMed ID: 30851334	2019
A Prospective Study of the Urinary and Gastrointestinal Microbiome in Prepubertal Males. Urology\| PubMed ID: 31195012	2019
Inflammation-associated pathologies in a case of prostate schistosomiasis: Implications for a causal role in prostate carcinogenesis. The Prostate\| PubMed ID: 31212384	2019
Lactoferrin CpG Island Hypermethylation and Decoupling of mRNA and Protein Expression in the Early Stages of Prostate Carcinogenesis. The American journal of pathology\| PubMed ID: 31499027	2019
IL8 Expression Is Associated with Prostate Cancer Aggressiveness and Androgen Receptor Loss in Primary and Metastatic Prostate Cancer. Molecular cancer research : MCR\| PubMed ID: 31604846	2020
The Potential Effects of Radiation on the Gut-Brain Axis. Radiation research\| PubMed ID: 31898468	2020
Racial Difference in Prostate Cancer Cell Telomere Lengths in Men with Higher Grade Prostate Cancer: A Clue to the Racial Disparity in Prostate Cancer Outcomes. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 31915143	2020
High Extratumoral Mast Cell Counts Are Associated with a Higher Risk of Adverse Prostate Cancer Outcomes. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 31932412	2020
Management of Chronic Bacterial Prostatitis. Current urology reports\| PubMed ID: 32488742	2020
Prostate carcinogenesis: inflammatory storms. Nature reviews. Cancer\| PubMed ID: 32546840	2020
Differential mast cell phenotypes in benign versus cancer tissues and prostate cancer oncologic outcomes. The Journal of pathology\| PubMed ID: 33338262	2021
Obesity is Associated with Shorter Telomere Length in Prostate Stromal Cells in Men with Aggressive Prostate Cancer. Cancer prevention research (Philadelphia, Pa.)\| PubMed ID: 33355185	2021
Why Do Epidemiologic Studies Find an Inverse Association Between Intraprostatic Inflammation and Prostate Cancer: A Possible Role for Colliding Bias? Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology\| PubMed ID: 33547143	2021
Feasibility of integrating canine olfaction with chemical and microbial profiling of urine to detect lethal prostate cancer. PloS one\| PubMed ID: 33596212	2021
The interplay of microbiota and hormone regulation in men with prostate cancer. Prostate cancer and prostatic diseases\| PubMed ID: 34007013	2021
GSTP1 positive prostatic adenocarcinomas are more common in Black than White men in the United States. PloS one\| PubMed ID: 34191807	2021
Oncogenic gene fusions in nonneoplastic precursors as evidence that bacterial infection can initiate prostate cancer. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 34341114	2021
Pathology Residency Program Special Expertise Tracks Meet the Needs of an Evolving Field. Academic pathology\| PubMed ID: 34485688	2021
P2X4 purinergic receptors offer a therapeutic target for aggressive prostate cancer. The Journal of pathology\| PubMed ID: 34652816	2022
Immune cell infiltrates and prognosis in localized prostate cancer. The Journal of pathology\| PubMed ID: 34694014	2022
Examining the Effects of 4He Exposure on the Gut-Brain Axis. Radiation research\| PubMed ID: 34752622	2022
Loss of SELENOF Induces the Transformed Phenotype in Human Immortalized Prostate Epithelial Cells. International journal of molecular sciences\| PubMed ID: 34769469	2021
Health inequity drives disease biology to create disparities in prostate cancer outcomes. The Journal of clinical investigation\| PubMed ID: 35104804	2022
Castration-mediated IL-8 promotes myeloid infiltration and prostate cancer progression. Nature cancer\| PubMed ID: 35122025	2021
Multiplex immunohistochemical phenotyping of T cells in primary prostate cancer. The Prostate\| PubMed ID: 35188986	2022
Association of B7-H3 expression with racial ancestry, immune cell density, and androgen receptor activation in prostate cancer. Cancer\| PubMed ID: 35333400	2022
Incorporation of Data From Multiple Hypervariable Regions when Analyzing Bacterial 16S rRNA Gene Sequencing Data. Frontiers in genetics\| PubMed ID: 35432480	2022
Modeling Human Prostate Cancer Metastasis in Mice Resection of Subcutaneous Allografts. Frontiers in oncology\| PubMed ID: 35574356	2022
P2 purinergic receptor dysregulation in urologic disease. Purinergic signalling\| PubMed ID: 35687210	2022
Composition of gastrointestinal microbiota in association with treatment response in individuals with metastatic castrate resistant prostate cancer progressing on enzalutamide and initiating... Neoplasia (New York, N.Y.)\| PubMed ID: 35908379	2022
Localization of macrophage subtypes and neutrophils in the prostate tumor microenvironment and their association with prostate cancer racial disparities. The Prostate\| PubMed ID: 35971807	2022
Association of self-identified race and genetic ancestry with the immunogenomic landscape of primary prostate cancer. JCI insight\| PubMed ID: 36752203	2023
Club-like cells in proliferative inflammatory atrophy of the prostate. The Journal of pathology\| PubMed ID: 37550827	2023
Intratumoral Bacteria as Mediators of Cancer Immunotherapy Response. Cancer research\| PubMed ID: 37712178	2023
FASN Gene Methylation is Associated with Fatty Acid Synthase Expression and Clinical-genomic Features of Prostate Cancer. Cancer research communications\| PubMed ID: 38112617	2024