Xin Jin

Eye Hospital, The first Affiliated Hospital of Harbin Medical University

Affiliated withThe first Affiliated Hospital of Harbin Medical University BGI Research South China University of Technology

Research Area

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title	2024
Publication title Cited by 1	2025

Other Publications

Article	Year
Bufalin Reverses Resistance to Sorafenib by Inhibiting Akt Activation in Hepatocellular Carcinoma: The Role of Endoplasmic Reticulum Stress. PloS one\| PubMed ID: 26381511	2015
Berberine affects osteosarcoma via downregulating the caspase-1/IL-1β signaling axis. Oncology reports\| PubMed ID: 28000894	2017
Circular RNA hsa-circ-0016347 promotes proliferation, invasion and metastasis of osteosarcoma cells. Oncotarget\| PubMed ID: 28424426	2017
Long Non-Coding RNA KCNQ1OT1 Promotes Cataractogenesis via miR-214 and Activation of the Caspase-1 Pathway. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 28535504	2017
miR-93-5p enhance lacrimal gland adenoid cystic carcinoma cell tumorigenesis by targeting BRMS1L. Cancer cell international\| PubMed ID: 29760585	2018
Pyroptosis, a novel mechanism implicated in cataracts. Molecular medicine reports\| PubMed ID: 29956729	2018
Long non-coding RNA MIAT competitively binds miR-150-5p to regulate ZEB1 expression in osteosarcoma. Oncology letters\| PubMed ID: 30655889	2019
Matrix Metalloproteases-Mediated Cleavage on β-Dystroglycan May Play a Key Role in the Blood-Brain Barrier After Intracerebral Hemorrhage in Rats. Medical science monitor : international medical journal of experimental and clinical research\| PubMed ID: 30686819	2019
Long non-coding RNA H19 promotes corneal neovascularization by targeting microRNA-29c. Bioscience reports\| PubMed ID: 30948500	2019
Long noncoding RNA KCNQ1OT1 induces pyroptosis in diabetic corneal endothelial keratopathy. American journal of physiology. Cell physiology\| PubMed ID: 31693400	2020
A family of fuchs endothelial corneal dystrophy and anterior polar cataract with an analysis of whole exome sequencing. Ophthalmic genetics\| PubMed ID: 32367751	2020
Ocular pathogens and antibiotic resistance in microbial keratitis over three years in Harbin, Northeast China. Acta ophthalmologica\| PubMed ID: 33565253	2021
Bilateral Limbal Stem Cell Alterations in Patients With Unilateral Herpes Simplex Keratitis and Herpes Zoster Ophthalmicus as Shown by In Vivo Confocal Microscopy. Investigative ophthalmology & visual science\| PubMed ID: 33974047	2021
Quantitative analysis of retinal vessel density and thickness changes in diabetes mellitus evaluated using optical coherence tomography angiography: a cross-sectional study. BMC ophthalmology\| PubMed ID: 34130654	2021
Long non‑coding RNA H19 regulates LASP1 expression in osteosarcoma by competitively binding to miR‑29a‑3p. Oncology reports\| PubMed ID: 34328197	2021
Activation of Conjunctiva-Associated Lymphoid Tissue in Patients With Infectious Keratitis Using In Vivo Confocal Microscopy. Investigative ophthalmology & visual science\| PubMed ID: 34427624	2021
Wedelolactone ameliorates Pseudomonas aeruginosa-induced inflammation and corneal injury by suppressing caspase-4/5/11/GSDMD-mediated non-canonical pyroptosis. Experimental eye research\| PubMed ID: 34481822	2021
Clinical Observation of Corneal Endothelial Plaques With Fungal and Bacterial Keratitis by Anterior Segment Optical Coherence Tomography and In Vivo Confocal Microscopy. Cornea\| PubMed ID: 34759198	2022
Observation of Conjunctiva-Associated Lymphoid Tissue With In Vivo Confocal Microscopy in Healthy Patients and Patients With Meibomian Gland Dysfunction. Cornea\| PubMed ID: 34759200	2022
Activation of Conjunctiva-Associated Lymphoid Tissue in Diabetic Patients. Ocular immunology and inflammation\| PubMed ID: 35113756	2023
Dexamethasone attenuates dry eye-induced pyroptosis by regulating the KCNQ1OT1/miR-214 cascade. Steroids\| PubMed ID: 35779698	2022
A 5-Year Retrospective Analysis of the Risk Factors, Treatment, and Prognosis of Patients With Fungal Keratitis in Heilongjiang, China. American journal of ophthalmology\| PubMed ID: 35932821	2022
Misdiagnosis and Treatment of Corneal Complications Caused by Suture Exposure After Buried-Suture Double-Eyelid Blepharoplasty. Aesthetic plastic surgery\| PubMed ID: 37653179	2023
Correlation Between Corneal Whorl-Like Nerve and Retinal Neurodegenerative Changes and Their Association With Microvessel Perfusion in Diabetes. Investigative ophthalmology & visual science\| PubMed ID: 38019489	2023
[Corrigendum] Long non‑coding RNA H19 regulates LASP1 expression in osteosarcoma by competitively binding to miR‑29a‑3p. Oncology reports\| PubMed ID: 38639176	2024
Identification and Verification of Ferroptosis-Related Genes in Keratoconus Using Bioinformatics Analysis. Journal of inflammation research\| PubMed ID: 38660574	2024
Misdiagnosis and Treatment of Corneal Complications Caused by Suture Exposure After Buried-Suture Double-Eyelid Blepharoplasty. Aesthetic plastic surgery\| PubMed ID: 38710812	2024
Loose suture-related ocular surface inflammation and activation of conjunctiva-associated lymphoid tissue in patients after keratoplasty. Scientific reports\| PubMed ID: 38714796	2024
Changes in the ocular surface microbiome of patients with coronavirus disease 2019 (COVID-19). Frontiers in microbiology\| PubMed ID: 39040901	2024
Integrated multi-omics analyses and functional validation reveal TTK as a novel EMT activator for endometrial cancer. Journal of translational medicine\| PubMed ID: 36829176	2023
Evaluation of the Impact of BaP Exposure on the Gut Microbiota and Allergic Responses in an OVA-Sensitized Mouse Model. Environmental health perspectives\| PubMed ID: 37267060	2023
Probiotic characteristics of Lactobacillus gasseri TF08-1: A cholesterol-lowering bacterium, isolated from human gut. Enzyme and microbial technology\| PubMed ID: 37321015	2023
The complete and fully-phased diploid genome of a male Han Chinese. Cell research\| PubMed ID: 37452091	2023
Integrated Human Skin Bacteria Genome Catalog Reveals Extensive Unexplored Habitat-Specific Microbiome Diversity and Function. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 37548643	2023
Metagenomic analysis of individual mosquitos reveals the ecology of insect viruses. bioRxiv : the preprint server for biology\| PubMed ID: 37732272	2023
The fragmentomic property of plasma cell-free DNA enables the non-invasive detection of diabetic nephropathy in patients with diabetes mellitus. Frontiers in endocrinology\| PubMed ID: 37867508	2023
A high-resolution haplotype-resolved Reference panel constructed from the China Kadoorie Biobank Study. Nucleic acids research\| PubMed ID: 37870428	2023
Live birth of chimeric monkey with high contribution from embryonic stem cells. Cell\| PubMed ID: 37949056	2023
Comparative genomic analysis reveals niche adaption of Lactobacillus acidophilus. Journal of applied microbiology\| PubMed ID: 38040628	2023
Single cell multi-omics reveal intra-cell-line heterogeneity across human cancer cell lines. Nature communications\| PubMed ID: 38071219	2023
Safety assessment of potential probiotic Lactobacillus acidophilus AM13-1 with high cholesterol-lowering capability isolated from human gut. Letters in applied microbiology\| PubMed ID: 38126115	2024
Characterizing immune variation and diagnostic indicators of preeclampsia by single-cell RNA sequencing and machine learning. Communications biology\| PubMed ID: 38182876	2024
Comparison of the DNBSEQ platform and Illumina HiSeq 2000 for bacterial genome assembly. Scientific reports\| PubMed ID: 38221534	2024
Effects of time-restricted eating on intrahepatic fat and metabolic health among patients with nonalcoholic fatty liver disease. Obesity (Silver Spring, Md.)\| PubMed ID: 38228496	2024
A genome-wide association study reveals the relationship between human genetic variation and the nasal microbiome. Communications biology\| PubMed ID: 38291185	2024
Cohort profile for the Tongji Cardiovascular Health Study: a prospective multiomics cohort study. BMJ open\| PubMed ID: 38365303	2024
Genomic and functional diversity of cultivated from human gut microbiota. Heliyon\| PubMed ID: 38463766	2024
Metagenomic analysis of individual mosquito viromes reveals the geographical patterns and drivers of viral diversity. Nature ecology & evolution\| PubMed ID: 38519631	2024
DAIS: a method for identifying spatial domains based on density clustering of spatial omics data. Journal of genetics and genomics = Yi chuan xue bao\| PubMed ID: 38599516	2024
Substantial viral diversity in bats and rodents from East Africa: insights into evolution, recombination, and cocirculation. Microbiome\| PubMed ID: 38600530	2024
Consistent signatures in the human gut microbiome of old- and young-onset colorectal cancer. Nature communications\| PubMed ID: 38649355	2024
Predicting prognosis and immunotherapy response in colorectal cancer by pericytes insights from single-cell RNA sequencing. Human molecular genetics\| PubMed ID: 38652261	2024
Plasma Circulating Cell-Free DNA Facilitated the Detection of an Alveolar Echinococcosis Patient Initially Misdiagnosed as Cystic Echinococcosis: A Case Report. Tropical medicine and infectious disease\| PubMed ID: 38668549	2024
Effects of blood-processing protocols on cell-free DNA fragmentomics in plasma: Comparisons of one- and two-step centrifugations. Clinica chimica acta; international journal of clinical chemistry\| PubMed ID: 38754575	2024
NIPT-PG: empowering non-invasive prenatal testing to learn from population genomics through an incremental pan-genomic approach. Briefings in bioinformatics\| PubMed ID: 38836702	2024
Isolation of potentially novel species expands the genomic and functional diversity of Lachnospiraceae. iMeta\| PubMed ID: 38882499	2024
A comprehensive whole genome database of ethnic minority populations. Scientific reports\| PubMed ID: 38886537	2024
Author Correction: A comprehensive whole genome database of ethnic minority populations. Scientific reports\| PubMed ID: 38982115	2024
INDELpred: Improving the prediction and interpretation of indel pathogenicity within the clinical genome. HGG advances\| PubMed ID: 38993112	2024
Cell-free DNA: a promising biomarker in infectious diseases. Trends in microbiology\| PubMed ID: 38997867	2025
Longitudinal integrative cell-free DNA analysis in gestational diabetes mellitus. Cell reports. Medicine\| PubMed ID: 39059385	2024
Single-cell multi-modal chromatin profiles revealing epigenetic regulations of cells in hepatocellular carcinoma. Clinical and translational medicine\| PubMed ID: 39210544	2024
COVID-19 in the Tibet, China, the roof of the world: a comparative analysis of high-altitude residents and newcomers. BMC infectious diseases\| PubMed ID: 39223453	2024
Insights into the assembly of the neovaginal microbiota in Mayer-Rokitansky-Küster-Hauser (MRKH) syndrome patients. Nature communications\| PubMed ID: 39242555	2024
The 1% gift to humanity: The Human Genome Project II. Cell research\| PubMed ID: 39261573	2024
An IGHG1 variant exhibits polarized prevalence and confers enhanced IgG1 antibody responses against life-threatening organisms. Nature immunology\| PubMed ID: 39261722	2024
Plasma Cell-Free DNA Concentration and Fragmentomes Predict Neoadjuvant Chemotherapy Response in Cervical Cancer Patients. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 39319610	2024
Whole-genome Sequencing Association Analysis of Quantitative Platelet Traits in A Large Cohort of β-thalassemia. Genomics, proteomics & bioinformatics\| PubMed ID: 39331630	2025
Fragmentomics of plasma mitochondrial and nuclear DNA inform prognosis in COVID-19 patients with critical symptoms. BMC medical genomics\| PubMed ID: 39363185	2024
Integrated large-scale metagenome assembly and multi-kingdom network analyses identify sex differences in the human nasal microbiome. Genome biology\| PubMed ID: 39380016	2024
Novel insights into the genetic architecture of pregnancy glycemic traits from 14,744 Chinese maternities. Cell genomics\| PubMed ID: 39389014	2024
Genome-wide association study of maternal plasma metabolites during pregnancy. Cell genomics\| PubMed ID: 39389015	2024
Genetic analyses of 104 phenotypes in 20,900 Chinese pregnant women reveal pregnancy-specific discoveries. Cell genomics\| PubMed ID: 39389017	2024
Utilizing non-invasive prenatal test sequencing data for human genetic investigation. Cell genomics\| PubMed ID: 39389018	2024
A genome-wide association study of neonatal metabolites. Cell genomics\| PubMed ID: 39389019	2024
A spatiotemporal transcriptomic atlas of mouse placentation. Cell discovery\| PubMed ID: 39438452	2024
Unraveling the impact of host genetics and factors on the urinary microbiome in a young population. mBio\| PubMed ID: 39513726	2024
Comprehensive evaluation of the impact of whole-genome bisulfite sequencing (WGBS) on the fragmentomic characteristics of plasma cell-free DNA. Clinica chimica acta; international journal of clinical chemistry\| PubMed ID: 39528065	2025
Uncovering disease-related multicellular pathway modules on large-scale single-cell transcriptomes with scPAFA. Communications biology\| PubMed ID: 39550507	2024
Cell-free DNA from clinical testing as a resource of population genetic analysis. Trends in genetics : TIG\| PubMed ID: 39578178	2025
Single-cell RNA sequencing of peripheral blood links cell-type-specific regulation of splicing to autoimmune and inflammatory diseases. Nature genetics\| PubMed ID: 39627432	2024
Mutations in AMBRA1 aggravate β-thalassemia by impairing autophagy-mediated clearance of free α-globin. Blood\| PubMed ID: 39693613	2025
Revealing an unprecedented diversity of episymbiotic Saccharibacteria in a high-quality genome collection. NPJ biofilms and microbiomes\| PubMed ID: 39702451	2024
Genomic landscape of medulloblastoma subtypes in an Asian cohort. Translational cancer research\| PubMed ID: 39816537	2024
Host Specificity and Geographic Dispersion Shape Virome Diversity in Rhinolophus Bats. Molecular ecology\| PubMed ID: 39825599	2025
Protocol for genetic analysis of population-scale ultra-low-depth sequencing data. STAR protocols\| PubMed ID: 39826115	2025
Inferring cell trajectories of spatial transcriptomics via optimal transport analysis. Cell systems\| PubMed ID: 39904341	2025
Multi-omics reveals immune response and metabolic profiles during high-altitude mountaineering. Cell reports\| PubMed ID: 39932189	2025
Unveiling spatial heterogeneity in medulloblastoma: A multi-omics analysis of cellular state and geographical organization. Neuro-oncology\| PubMed ID: 39957311	2025
Spatiotemporal Transcriptomic Profiling Reveals the Dynamic Immunological Landscape of Alveolar Echinococcosis. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 39985260	2025
Multi-omics approach reveals the impact of prognosis model-related genes on the tumor microenvironment in medulloblastoma. Frontiers in oncology\| PubMed ID: 40104502	2025
Wide-spectrum profiling of plasma cell-free RNA and the potential for health-monitoring. RNA biology\| PubMed ID: 40110666	2025
Whole-genomic comparison reveals complex population dynamics and parasitic adaptation of . mBio\| PubMed ID: 40207926	2025
Comprehensive evaluation of methods for identifying tissues or cell types of origin of the plasma cell-free transcriptome. PeerJ\| PubMed ID: 40256737	2025
A Chinese pediatric patient with thalassemia traits and compound heterozygous mutations in the ene suspected of having dehydrated hereditary stomatocytosis. Hematology (Amsterdam, Netherlands)\| PubMed ID: 40320770	2025
Efficiently constructing complete genomes with CycloneSEQ to fill gaps in bacterial draft assemblies. GigaByte (Hong Kong, China)\| PubMed ID: 40329937	2025
Targeting VSIG4 tissue-resident macrophages enhances T cell cytotoxicity and immunotherapy efficacy in cancer. Developmental cell\| PubMed ID: 40339578	2025
Shared genetic features inference among hypoxia-ischemia diseases in the presence of heterogenous omics data based on a novel risk assessment method. Frontiers in genetics\| PubMed ID: 40357364	2025
Identification and Evaluation of the Urinary Microbiota Associated With Bladder Cancer. Cancer innovation\| PubMed ID: 40417381	2025
Cell-Free DNA Comprises the Strand-Specific Characteristic Associated with Transcription and Methylation. Clinical chemistry\| PubMed ID: 40518704	2025
Echinococcosis on the Tibetan Plateau, where to go? Trends in parasitology\| PubMed ID: 40675862	2025
Integrating metagenomics and cultivation unveils oral phage diversity and potential impact on hosts. NPJ biofilms and microbiomes\| PubMed ID: 40715125	2025
SpaSEG: unsupervised deep learning for multi-task analysis of spatially resolved transcriptomics. Genome biology\| PubMed ID: 40734184	2025
Non-coding genetic elements of lung cancer identified using whole genome sequencing in 13,722 Chinese. Nature communications\| PubMed ID: 40783572	2025
Integrative single-cell transcriptomic analysis deciphers heterogeneous characteristics of gastrointestinal tract cancer. Clinical and translational medicine\| PubMed ID: 40785647	2025
Cultivation and sequencing of microbiota members unveil the functional potential of yak gut microbiota. mSystems\| PubMed ID: 40815469	2025
Cell-free DNA as a potential alternative to genomic DNA in genetic studies. NAR genomics and bioinformatics\| PubMed ID: 40918064	2025
PangenomeX: a graph convolutional network-based pangenome framework for unbiased population-scale genomic variation analysis. Briefings in bioinformatics\| PubMed ID: 41115209	2025
ZIPcnv: accurate and efficient inference of copy number variations from shallow whole-genome sequencing. Bioinformatics (Oxford, England)\| PubMed ID: 41138169	2025
SLPI⁺ AT2-Like Cells Orchestrate Lung Adenocarcinoma Invasion via Wnt Pathway Activation and Stromal Crosstalk in a Spatially Defined Margin Niche. Advanced science (Weinheim, Baden-Wurttemberg, Germany)\| PubMed ID: 41216859	2025
The right is more conservative than the left: a postnatal hypothesis of handedness based on mice. Journal of genetics and genomics = Yi chuan xue bao\| PubMed ID: 41248751	2025
X-LDR: an atlas of linkage disequilibrium across species. Genome biology\| PubMed ID: 41267068	2025
Tracing the tissue origin of cell-free DNA through open chromatin footprint. Communications biology\| PubMed ID: 41291034	2025
Whole-genome profiling of age- and sex-associated DNA methylation signatures in human plasma cell-free DNA. Communications medicine\| PubMed ID: 41315810	2025
Identification of a Patient with Transfusion-Dependent β-Thalassemia Caused by Compound Heterozygous Mutations of : C.84_85insC and Common Linked Intronic Variants in . Hemoglobin\| PubMed ID: 41378683	2025