Martin G. Sirois

Montreal Heart Institute

Affiliated withMontreal Heart Institute Université de Montréal

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2024

Other Publications

Article	Year
VEGF stimulation of endothelial cell PAF synthesis is mediated by group V 14 kDa secretory phospholipase A2. British journal of pharmacology\| PubMed ID: 11522612	2001
Regulation of VEGF-induced endothelial cell PAF synthesis: role of p42/44 MAPK, p38 MAPK and PI3K pathways. British journal of pharmacology\| PubMed ID: 11704645	2001
Blockade of in vivo VEGF-mediated angiogenesis by antisense gene therapy: role of Flk-1 and Flt-1 receptors. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 11748063	2002
Relative effects of VEGF-A and VEGF-C on endothelial cell proliferation, migration and PAF synthesis: Role of neuropilin-1. Journal of cellular biochemistry\| PubMed ID: 11968003	2002
Subacute and chronic effects of quinapril on cardiac cytokine expression, remodeling, and function after myocardial infarction in the rat. Journal of cardiovascular pharmacology\| PubMed ID: 12021578	2002
Estrogen regulation of endothelial and smooth muscle cell migration and proliferation: role of p38 and p42/44 mitogen-activated protein kinase. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 12377734	2002
Immediate and delayed VEGF-mediated NO synthesis in endothelial cells: role of PI3K, PKC and PLC pathways. British journal of pharmacology\| PubMed ID: 12429574	2002
Lower incidence of thrombus formation with cryoenergy versus radiofrequency catheter ablation. Circulation\| PubMed ID: 12668527	2003
Effects of acute rejection on L-arginine/iNOS pathway in canine heart transplantation. The Canadian journal of cardiology\| PubMed ID: 12704490	2003
Specific contribution of estrogen receptors on mitogen-activated protein kinase pathways and vascular cell activation. Circulation research\| PubMed ID: 12893737	2003
Sphingosine 1-phosphate effect on endothelial cell PAF synthesis: role in cellular migration. Journal of cellular biochemistry\| PubMed ID: 14587028	2003
Prevention of in-stent restenosis via reduction of thrombo-inflammatory reactions with recombinant P-selectin glycoprotein ligand-1. Thrombosis and haemostasis\| PubMed ID: 15175806	2004
Angiopoietins can directly activate endothelial cells and neutrophils to promote proinflammatory responses. Blood\| PubMed ID: 15498854	2005
Effect of chronic exercise and Angiotensin-converting enzyme inhibition on rodent thoracic aorta. Journal of cardiovascular pharmacology\| PubMed ID: 15505496	2004
Percutaneous endoluminal arterial cryoenergy improves vascular remodelling after angioplasty. Thrombosis and haemostasis\| PubMed ID: 15543341	2004
Vascular endothelial growth factor (VEGF)-A165-induced prostacyclin synthesis requires the activation of VEGF receptor-1 and -2 heterodimer. The Journal of biological chemistry\| PubMed ID: 15637071	2005
Local delivery of 17beta-estradiol improves reendothelialization and decreases inflammation after coronary stenting in a porcine model. Thrombosis and haemostasis\| PubMed ID: 16363248	2005
Endovascular cryotherapy accentuates the accumulation of the fibrillar collagen types I and III after percutaneous transluminal angioplasty in pigs. Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists\| PubMed ID: 16445314	2006
Role of MSK1 in the signaling pathway leading to VEGF-mediated PAF synthesis in endothelial cells. Journal of cellular biochemistry\| PubMed ID: 16479592	2006
Angiopoietins-1 and -2 are both capable of mediating endothelial PAF synthesis: intracellular signalling pathways. Cellular signalling\| PubMed ID: 16617006	2006
Estradiol blocks the induction of CD40 and CD40L expression on endothelial cells and prevents neutrophil adhesion: an ERalpha-mediated pathway. Cardiovascular research\| PubMed ID: 16797503	2006
Vascular permeability induced by VEGF family members in vivo: role of endogenous PAF and NO synthesis. Journal of cellular biochemistry\| PubMed ID: 17115409	2007
Angiopoietin chemotactic activities on neutrophils are regulated by PI-3K activation. Journal of leukocyte biology\| PubMed ID: 17215522	2007
HIF2 alpha reduces growth rate but promotes angiogenesis in a mouse model of neuroblastoma. BMC cancer\| PubMed ID: 17655754	2007
Angiopoietin-mediated endothelial P-selectin translocation: cell signaling mechanisms. Journal of leukocyte biology\| PubMed ID: 17984290	2008
Priming effect of homocysteine on inducible vascular cell adhesion molecule-1 expression in endothelial cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 18406566	2008
Local delivery of 17-beta-estradiol modulates collagen content in coronary porcine arteries after PTCA and stent implantation. Journal of vascular research\| PubMed ID: 18451633	2008
Endothelial progenitor cells bind and inhibit platelet function and thrombus formation. Circulation\| PubMed ID: 19917882	2009
Expression and release of angiopoietin-1 from human neutrophils: intracellular mechanisms. Growth factors (Chur, Switzerland)\| PubMed ID: 19919521	2009
Group V secreted phospholipase A2 contributes to LPS-induced leukocyte recruitment. Journal of cellular physiology\| PubMed ID: 20232296	2010
Identification of VEGF receptor-2 tyrosine phosphorylation sites involved in VEGF-mediated endothelial platelet-activating factor synthesis. Canadian journal of physiology and pharmacology\| PubMed ID: 20962896	2010
Characterization of FGF receptor expression in human neutrophils and their contribution to chemotaxis. American journal of physiology. Cell physiology\| PubMed ID: 21795520	2011
Angiopoietin-1 but not angiopoietin-2 induces IL-8 synthesis and release by human neutrophils. Journal of cellular physiology\| PubMed ID: 22015631	2012
Differences in biomarkers in patients with heart failure with a reduced vs a preserved left ventricular ejection fraction. The Canadian journal of cardiology\| PubMed ID: 22104539	2012
Angiopoietin-1 but not angiopoietin-2 promotes neutrophil viability: Role of interleukin-8 and platelet-activating factor. Biochimica et biophysica acta\| PubMed ID: 22198097	2012
Angiopoietin-1 upregulates de novo expression of IL-1β and Il1-Ra, and the exclusive release of Il1-Ra from human neutrophils. PloS one\| PubMed ID: 24563688	2014
Changes in cardiopulmonary reserve and peripheral arterial function concomitantly with subclinical inflammation and oxidative stress in patients with heart failure with preserved ejection fr... International journal of vascular medicine\| PubMed ID: 24719767	2014
Effect of everolimus on the immunomodulation of the human neutrophil inflammatory response and activation. Cellular & molecular immunology\| PubMed ID: 24882386	2015
Heart failure with anemia: novel findings on the roles of renal disease, interleukins, and specific left ventricular remodeling processes. Circulation. Heart failure\| PubMed ID: 25027873	2014
VEGF and angiopoietins promote inflammatory cell recruitment and mature blood vessel formation in murine sponge/Matrigel model. Journal of cellular biochemistry\| PubMed ID: 25145474	2015
Decreased circulating and neutrophil mediated VEGF-A165 release in stable long-term cardiac transplant recipients. Vascular cell\| PubMed ID: 25922663	2015
Indoleamine 2,3-Dioxygenase-Expressing Aortic Plasmacytoid Dendritic Cells Protect against Atherosclerosis by Induction of Regulatory T Cells. Cell metabolism\| PubMed ID: 27166946	2016
New Insights into the Pro-Inflammatory Activities of Ang1 on Neutrophils: Induction of MIP-1β Synthesis and Release. PloS one\| PubMed ID: 27632174	2016
Focal Transcatheter Cryoablation: Is a Four-Minute Application Still Required? Journal of cardiovascular electrophysiology\| PubMed ID: 28233925	2017
Synthesis of Human Neutrophil Extracellular Traps Contributes to Angiopoietin-Mediated In Vitro Proinflammatory and Proangiogenic Activities. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 29686052	2018
Subclinical Inflammation in Heart Failure: A Neutrophil Perspective. The Canadian journal of cardiology\| PubMed ID: 29801737	2018
Cardiopulmonary, biomarkers, and vascular responses to acute hypoxia following cardiac transplantation. Clinical transplantation\| PubMed ID: 30047602	2018
A comparison of the effects of selective and non-selective mineralocorticoid antagonism on glucose homeostasis of heart failure patients with glucose intolerance or type II diabetes: A rando... American heart journal\| PubMed ID: 30097164	2018
PBI-4050 reduces pulmonary hypertension, lung fibrosis, and right ventricular dysfunction in heart failure. Cardiovascular research\| PubMed ID: 30753422	2020
MK5 haplodeficiency decreases collagen deposition and scar size during post-myocardial infarction wound repair. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 30901279	2019
CRP Induces NETosis in Heart Failure Patients with or without Diabetes. ImmunoHorizons\| PubMed ID: 31399487	2019
Right Atrial Mechanisms of Atrial Fibrillation in a Rat Model of Right Heart Disease. Journal of the American College of Cardiology\| PubMed ID: 31488271	2019
Increased Circulating Levels of Neutrophil Extracellular Traps During Cardiopulmonary Bypass. CJC open\| PubMed ID: 32190824	2020
Acute Vascular Benefits of Finnish Sauna Bathing in Patients With Stable Coronary Artery Disease. The Canadian journal of cardiology\| PubMed ID: 32615263	2021
Lymphocytopenia During Hospitalization for Acute Heart Failure and Its Relationship With Portal Congestion and Right Ventricular Function. Journal of cardiac failure\| PubMed ID: 32659436	2020
Impact of Finnish sauna bathing on circulating markers of inflammation in healthy middle-aged and older adults: A crossover study. Complementary therapies in medicine\| PubMed ID: 32951736	2020
Colchicine reduces lung injury in experimental acute respiratory distress syndrome. PloS one\| PubMed ID: 33264297	2020
Impact of diabetes on serum biomarkers in heart failure with preserved ejection fraction: insights from the TOPCAT trial. ESC heart failure\| PubMed ID: 33438360	2021
MK2-Deficient Mice Are Bradycardic and Display Delayed Hypertrophic Remodeling in Response to a Chronic Increase in Afterload. Journal of the American Heart Association\| PubMed ID: 33533257	2021
Angiopoietin 1 release from human neutrophils is independent from neutrophil extracellular traps (NETs). BMC immunology\| PubMed ID: 34344299	2021
Neutrophils pro-inflammatory and anti-inflammatory cytokine release in patients with heart failure and reduced ejection fraction. ESC heart failure\| PubMed ID: 34382750	2021
Cholesterol absorption blocker ezetimibe prevents muscle wasting in severe dysferlin-deficient and mdx mice. Journal of cachexia, sarcopenia and muscle\| PubMed ID: 34927367	2022
Acute effect of passive heat exposure on markers of cardiometabolic function in adults with type 2 diabetes mellitus. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 35323077	2022
Neutrophils and Circulating Inflammatory Biomarkers in Diabetes Mellitus and Heart Failure With Preserved Ejection Fraction. The American journal of cardiology\| PubMed ID: 35811144	2022
Growth Differentiation Factor-15 as a Predictor of Functional Capacity, Frailty, and Ventricular Dysfunction in Patients With Aortic Stenosis and Preserved Left Ventricular Ejection Fraction... The American journal of cardiology\| PubMed ID: 36334433	2023
Correlation between Neutrophil Extracellular Traps (NETs) Expression and Primary Graft Dysfunction Following Human Lung Transplantation. Cells\| PubMed ID: 36359815	2022
Structural dysregulation of the pulmonary autograft was associated with a greater density of p16-vascular smooth muscle cells. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology\| PubMed ID: 36529416	2023
Chymase Inhibition Resolves and Prevents Deep Vein Thrombosis Without Increasing Bleeding Time in the Mouse Model. Journal of the American Heart Association\| PubMed ID: 36752268	2023
An inflammation resolution-promoting intervention prevents atrial fibrillation caused by left ventricular dysfunction. Cardiovascular research\| PubMed ID: 38091977	2024
The role of cellular senescence in profibrillatory atrial remodelling associated with cardiac pathology. Cardiovascular research\| PubMed ID: 38181429	2024
Low-Density Neutrophils Contribute to Subclinical Inflammation in Patients with Type 2 Diabetes. International journal of molecular sciences\| PubMed ID: 38338951	2024
A genetic mouse model of lean-NAFLD unveils sexual dimorphism in the liver-heart axis. Communications biology\| PubMed ID: 38519536	2024
Atrial cardiomyocytes contribute to the inflammatory status associated with atrial fibrillation in right heart disease. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology\| PubMed ID: 38546222	2024
Low-Density Neutrophils and Neutrophil Extracellular Traps (NETs) Are New Inflammatory Players in Heart Failure. The Canadian journal of cardiology\| PubMed ID: 38555028	2024
ERK3 is involved in regulating cardiac fibroblast function. Physiological reports\| PubMed ID: 38872461	2024
Daily exposure to chlordecone, an organochlorine pesticide, increases cardiac fibrosis and atrial fibrillation vulnerability. Journal of hazardous materials\| PubMed ID: 39173376	2024