Hermann Einsele

Medizinische Klinik und Poliklinik II und Lehrstuhl für Zelluläre Immuntherapie, Universitätsklinikum Würzburg

Affiliated withUniversitätsklinikum Würzburg

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 7	2024

Other Publications

Article	Year
Autologous stem-cell transplantation as first-line therapy in peripheral T-cell lymphomas: results of a prospective multicenter study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 19029417	2009
Primary prophylaxis of invasive fungal infections in patients with hematologic malignancies. Recommendations of the Infectious Diseases Working Party of the German Society for Haematology an... Haematologica\| PubMed ID: 19066334	2009
The temporal dynamics of differential gene expression in Aspergillus fumigatus interacting with human immature dendritic cells in vitro. PloS one\| PubMed ID: 21264256	2011
Human NK cells display important antifungal activity against Aspergillus fumigatus, which is directly mediated by IFN-γ release. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 21697457	2011
Molecular techniques in the diagnosis of deep and systemic mycosis. Clinics in dermatology\| PubMed ID: 23068152	2012
Deep molecular response is reached by the majority of patients treated with imatinib, predicts survival, and is achieved more quickly by optimized high-dose imatinib: results from the random... Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 24297946	2014
Distinct and complementary roles for Aspergillus fumigatus-specific Tr1 and Foxp3+ regulatory T cells in humans and mice. Immunology and cell biology\| PubMed ID: 24820384	2014
Distinct characteristics of e13a2 versus e14a2 BCR-ABL1 driven chronic myeloid leukemia under first-line therapy with imatinib. Haematologica\| PubMed ID: 24837466	2014
Donor cytomegalovirus status influences the outcome of allogeneic stem cell transplant: a study by the European group for blood and marrow transplantation. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America\| PubMed ID: 24850801	2014
Phase II trial of the anti-CD19 bispecific T cell-engager blinatumomab shows hematologic and molecular remissions in patients with relapsed or refractory B-precursor acute lymphoblastic leuk... Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 25385737	2014
Allogeneic Stem-Cell Transplantation in Patients With NPM1-Mutated Acute Myeloid Leukemia: Results From a Prospective Donor Versus No-Donor Analysis of Patients After Upfront HLA Typing With... Journal of clinical oncology : official journal of the American Society of Clinical Oncology\| PubMed ID: 25547501	2015
In vivo molecular imaging of chemokine receptor CXCR4 expression in patients with advanced multiple myeloma. EMBO molecular medicine\| PubMed ID: 25736399	2015
Elotuzumab Therapy for Relapsed or Refractory Multiple Myeloma. The New England journal of medicine\| PubMed ID: 26035255	2015
Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2, randomised contro... The Lancet. Oncology\| PubMed ID: 26549589	2015
Allogeneic Stem Cell Transplantation Improves Survival in Patients with Acute Myeloid Leukemia Characterized by a High Allelic Ratio of Mutant FLT3-ITD. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation\| PubMed ID: 26551637	2016
First-in-Human Experience of CXCR4-Directed Endoradiotherapy with 177Lu- and 90Y-Labeled Pentixather in Advanced-Stage Multiple Myeloma with Extensive Intra- and Extramedullary Disease. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 26564323	2016
TP53 mutation in patients with high-risk acute myeloid leukaemia treated with allogeneic haematopoietic stem cell transplantation. British journal of haematology\| PubMed ID: 26771088	2016
Proteomic Profiling of Serological Responses to Aspergillus fumigatus Antigens in Patients with Invasive Aspergillosis. Journal of proteome research\| PubMed ID: 26974881	2016
Survival of elderly patients with multiple myeloma-Effect of upfront autologous stem cell transplantation. European journal of cancer (Oxford, England : 1990)\| PubMed ID: 27185572	2016
Autotransplant with and without induction chemotherapy in older multiple myeloma patients: long-term outcome of a randomized trial. Haematologica\| PubMed ID: 27662018	2016
Myeloma CARs are rolling into the clinical arena. Blood\| PubMed ID: 27688779	2016
Panobinostat induces CD38 upregulation and augments the antimyeloma efficacy of daratumumab. Blood\| PubMed ID: 28476749	2017
SLAMF7-CAR T cells eliminate myeloma and confer selective fratricide of SLAMF7 normal lymphocytes. Blood\| PubMed ID: 29089311	2017
Outcome of patients with relapsed/refractory acute lymphoblastic leukemia after blinatumomab failure: No change in the level of CD19 expression. American journal of hematology\| PubMed ID: 29178361	2018
Letermovir Prophylaxis for Cytomegalovirus in Hematopoietic-Cell Transplantation. The New England journal of medicine\| PubMed ID: 29211658	2017
Human and Murine Innate Immune Cell Populations Display Common and Distinct Response Patterns during Their Interaction with the Pathogenic Mold . Frontiers in immunology\| PubMed ID: 29270175	2017
CAR T-cells targeting FLT3 have potent activity against FLT3ITD AML and act synergistically with the FLT3-inhibitor crenolanib. Leukemia\| PubMed ID: 29472720	2018
Feasibility of CXCR4-Directed Radioligand Therapy in Advanced Diffuse Large B-Cell Lymphoma. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 29777009	2019
Antiviral prophylaxis for cytomegalovirus infection in allogeneic hematopoietic cell transplantation. Blood advances\| PubMed ID: 30154125	2018
CAR T cells targeting αβ integrin are effective against advanced cancer in preclinical models. Advances in cell and gene therapy\| PubMed ID: 30420973	2018
Immunomodulation as a Therapy for Infection: Current Status and Future Perspectives. Journal of fungi (Basel, Switzerland)\| PubMed ID: 30558125	2018
Functionally Defective T Cells After Chemotherapy of B-Cell Malignancies Can Be Activated by the Tetravalent Bispecific CD19/CD3 Antibody AFM11. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 31090657	2019
The tyrosine kinase inhibitor dasatinib acts as a pharmacologic on/off switch for CAR T cells. Science translational medicine\| PubMed ID: 31270272	2019
Super-resolution microscopy reveals ultra-low CD19 expression on myeloma cells that triggers elimination by CD19 CAR-T. Nature communications\| PubMed ID: 31316055	2019
mutations and impact on clinical outcome: an analysis in 1,604 patients with newly diagnosed acute myeloid leukemia. Haematologica\| PubMed ID: 31413097	2020
ROR1-CAR T cells are effective against lung and breast cancer in advanced microphysiologic 3D tumor models. JCI insight\| PubMed ID: 31415244	2019
The use of bispecific antibodies to optimize the outcome of patients with acute leukemia, lymphoma and multiple myeloma after SCT. Bone marrow transplantation\| PubMed ID: 31431702	2019
Allogeneic transplantation in multiple myeloma: long-term follow-up and cytogenetic subgroup analysis. Leukemia\| PubMed ID: 31462732	2019
A highly soluble Sleeping Beauty transposase improves control of gene insertion. Nature biotechnology\| PubMed ID: 31685959	2019
Management of adults and children undergoing chimeric antigen receptor T-cell therapy: best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and t... Haematologica\| PubMed ID: 31753925	2020
β-. Journal for immunotherapy of cancer\| PubMed ID: 32303620	2020
Upregulation of CD38 expression on multiple myeloma cells by novel HDAC6 inhibitors is a class effect and augments the efficacy of daratumumab. Leukemia\| PubMed ID: 32350373	2021
Continuous renal replacement therapy in cytokine release syndrome following immunotherapy or cellular therapies? Journal for immunotherapy of cancer\| PubMed ID: 32474415	2020
Autologous stem cell transplantation in multiple myeloma patients: utilization patterns and hospital effects. Leukemia & lymphoma\| PubMed ID: 32476543	2020
Does time from diagnosis to treatment affect the prognosis of patients with newly diagnosed acute myeloid leukemia? Blood\| PubMed ID: 32496541	2020
Inefficient CAR-proximal signaling blunts antigen sensitivity. Nature immunology\| PubMed ID: 32632291	2020
What is the future of immunotherapy in multiple myeloma? Blood\| PubMed ID: 32735639	2020
Clinical data, limitations and perspectives on chimeric antigen receptor T-cell therapy in multiple myeloma. Current opinion in oncology\| PubMed ID: 32740095	2020
Elotuzumab, lenalidomide, and dexamethasone in RRMM: final overall survival results from the phase 3 randomized ELOQUENT-2 study. Blood cancer journal\| PubMed ID: 32887873	2020
Immune-based Therapies for Hematological Malignancies: An Update by the EHA SWG on Immunotherapy of Hematological Malignancies. HemaSphere\| PubMed ID: 32904089	2020
BATF3 programs CD8 T cell memory. Nature immunology\| PubMed ID: 32989328	2020
Dihydropyrimidine Dehydrogenase Testing prior to Treatment with 5-Fluorouracil, Capecitabine, and Tegafur: A Consensus Paper. Oncology research and treatment\| PubMed ID: 33099551	2020
Polymorphisms within the and Loci Influence the Risk of Developing Invasive Aspergillosis: A Two-Stage Case Control Study in the Context of the aspBIOmics Consortium. Journal of fungi (Basel, Switzerland)\| PubMed ID: 33374839	2020
Decitabine treatment in 311 patients with acute myeloid leukemia: outcome and impact of mutations - a registry based analysis. Leukemia & lymphoma\| PubMed ID: 33399480	2021
Sorafenib or placebo in patients with newly diagnosed acute myeloid leukaemia: long-term follow-up of the randomized controlled SORAML trial. Leukemia\| PubMed ID: 33603142	2021
Health Economic Aspects of Chimeric Antigen Receptor T-cell Therapies for Hematological Cancers: Present and Future. HemaSphere\| PubMed ID: 33880433	2021
Loss-of-Function Mutations of Are an Independent Marker of Adverse Outcomes in Intensively Treated Patients with Acute Myeloid Leukemia. Cancers\| PubMed ID: 33926021	2021
Second allogeneic transplants for multiple myeloma: a report from the EBMT Chronic Malignancies Working Party. Bone marrow transplantation\| PubMed ID: 33976382	2021
Full or intensity-reduced high-dose melphalan and single or double autologous stem cell transplant with or without bortezomib consolidation in patients with newly diagnosed multiple myeloma. European journal of haematology\| PubMed ID: 34270825	2021
Siglec-6 is a novel target for CAR T-cell therapy in acute myeloid leukemia. Blood\| PubMed ID: 34289026	2021
CEBPA mutations in 4708 patients with acute myeloid leukemia: differential impact of bZIP and TAD mutations on outcome. Blood\| PubMed ID: 34320176	2022
[Vorwort]. Oncology research and treatment\| PubMed ID: 34344011	2021
Impact of PTPN11 mutations on clinical outcome analyzed in 1529 patients with acute myeloid leukemia. Blood advances\| PubMed ID: 34459887	2021
Male-Specific Late Effects in Adult Hematopoietic Cell Transplantation Recipients: A Systematic Review from the Late Effects and Quality of Life Working Committee of the Center for Internati... Transplantation and cellular therapy\| PubMed ID: 34757220	2022
Differential impact of IDH1/2 mutational subclasses on outcome in adult AML: results from a large multicenter study. Blood advances\| PubMed ID: 34794176	2022
Current Limitations and Perspectives of Chimeric Antigen Receptor-T-Cells in Acute Myeloid Leukemia. Cancers\| PubMed ID: 34944782	2021
Incidence and management of CAR-T neurotoxicity in patients with multiple myeloma treated with ciltacabtagene autoleucel in CARTITUDE studies. Blood cancer journal\| PubMed ID: 35210399	2022
Allogeneic hematopoietic stem cell transplantation for adult HLH: a retrospective study by the chronic malignancies and inborn errors working parties of EBMT. Bone marrow transplantation\| PubMed ID: 35332305	2022
Male-specific late effects in adult hematopoietic cell transplantation recipients: a systematic review from the Late Effects and Quality of Life Working Committee of the Center for Internati... Bone marrow transplantation\| PubMed ID: 35523848	2022
[Monoclonal gammopathy of (un)known significance]. Deutsche medizinische Wochenschrift (1946)\| PubMed ID: 35636418	2022
[Vorwort des DGHO-Vorstandes]. Oncology research and treatment\| PubMed ID: 35871509	2022
[Klinische Studien in der Hämatologie und Onkologie]. Oncology research and treatment\| PubMed ID: 35871514	2022
Impact of IDH1 and IDH2 mutational subgroups in AML patients after allogeneic stem cell transplantation. Journal of hematology & oncology\| PubMed ID: 36064577	2022
Adjusted comparison of outcomes between patients from CARTITUDE-1 multiple myeloma patients with prior exposure to proteasome inhibitors, immunomodulatory drugs and anti-CD38 antibody from ... Haematologica\| PubMed ID: 36546453	2023
All-trans retinoic acid works synergistically with the γ-secretase inhibitor crenigacestat to augment BCMA on multiple myeloma and the efficacy of BCMA-CAR T cells. Haematologica\| PubMed ID: 36722406	2023
Comparative Efficacy of Teclistamab Versus Current Treatments in Real-World Clinical Practice in the Prospective LocoMMotion Study in Patients with Triple-Class-Exposed Relapsed and/or Refra... Advances in therapy\| PubMed ID: 36961654	2023
UBTF tandem duplications are rare but recurrent alterations in adult AML and associated with younger age, myelodysplasia, and inferior outcome. Blood cancer journal\| PubMed ID: 37236968	2023
Cilta-cel or Standard Care in Lenalidomide-Refractory Multiple Myeloma. The New England journal of medicine\| PubMed ID: 37272512	2023
Venetoclax salvage therapy in relapsed/refractory multiple myeloma. Haematologica\| PubMed ID: 37794827	2024
CAR T-cell therapy in multiple myeloma: mission accomplished? Blood\| PubMed ID: 38033289	2024
Comparative Effectiveness of Teclistamab Versus Real-World Physician's Choice of Therapy in LocoMMotion and MoMMent in Triple-Class Exposed Relapsed/Refractory Multiple Myeloma. Advances in therapy\| PubMed ID: 38110653	2024
Bispecific Antibodies in the Treatment of Multiple Myeloma. Hematology/oncology clinics of North America\| PubMed ID: 38199897	2024
Comparative Efficacy of Talquetamab vs. Current Treatments in the LocoMMotion and MoMMent Studies in Patients with Triple-Class-Exposed Relapsed/Refractory Multiple Myeloma. Advances in therapy\| PubMed ID: 38402374	2024
International Myeloma Working Group immunotherapy committee consensus guidelines and recommendations for optimal use of T-cell-engaging bispecific antibodies in multiple myeloma. The Lancet. Oncology\| PubMed ID: 38697166	2024
Therapeutic advances of targeting receptor tyrosine kinases in cancer. Signal transduction and targeted therapy\| PubMed ID: 39138146	2024
Next-generation BCMA-targeted chimeric antigen receptor CARTemis-1: the impact of manufacturing procedure on CAR T-cell features. Cellular oncology (Dordrecht, Netherlands)\| PubMed ID: 39192092	2024
LocoMMotion: a study of real-life current standards of care in triple-class exposed patients with relapsed/refractory multiple myeloma - 2-year follow-up (final analysis). Leukemia\| PubMed ID: 39322709	2024
Sporadic late onset nemaline myopathy and immunoglobulin deposition disease. Muscle & nerve\| PubMed ID: 23873431	2013
Long-term survival and T-cell kinetics in relapsed/refractory ALL patients who achieved MRD response after blinatumomab treatment. Blood\| PubMed ID: 26480933	2015
Common Genetic Polymorphisms within NFκB-Related Genes and the Risk of Developing Invasive Aspergillosis. Frontiers in microbiology\| PubMed ID: 27570521	2016
CXCR4-directed endoradiotherapy induces high response rates in extramedullary relapsed Multiple Myeloma. Theranostics\| PubMed ID: 28529638	2017
Chimeric Antigen Receptor Library Screening Using a Novel NF-κB/NFAT Reporter Cell Platform. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 30573301	2019
Clinical Approach to the Patient in Critical State Following Immunotherapy and/or Stem Cell Transplantation: Guideline for the On-Call Physician. Journal of clinical medicine\| PubMed ID: 31226876	2019
Response to daratumumab in rituximab-resistant EBV-associated PTLD following allogenic stem cell transplantation from an EBV seronegative donor. Leukemia & lymphoma\| PubMed ID: 31317812	2019
R-CHOP intensification with mid-cycle methotrexate and consolidating AraC/TT with BCNU/aHSCT in primary aggressive lymphoma with CNS involvement. Journal of cancer research and clinical oncology\| PubMed ID: 34085097	2022
Publisher Correction: Upregulation of CD38 expression on multiple myeloma cells by novel HDAC6 inhibitors is a class effect and augments the efficacy of daratumumab. Leukemia\| PubMed ID: 34845317	2022
A Clinical Case of COVID-19-Associated Pulmonary Aspergillosis (CAPA), Illustrating the Challenges in Diagnosis (Despite Overwhelming Mycological Evidence). Journal of fungi (Basel, Switzerland)\| PubMed ID: 35050021	2022
LocoMMotion: a prospective, non-interventional, multinational study of real-life current standards of care in patients with relapsed and/or refractory multiple myeloma. Leukemia\| PubMed ID: 35332278	2022
Characteristics and outcome of patients with acute myeloid leukemia and trisomy 4. Haematologica\| PubMed ID: 35678031	2023
Highjacking myeloma's niche with beefed-up CAR-Ts. Blood\| PubMed ID: 35771562	2022
CAR T cells targeting are effective at treating invasive pulmonary aspergillosis in preclinical models. Science translational medicine\| PubMed ID: 36170447	2022
[Vorwort des DGHO-Vorstands]. Oncology research and treatment\| PubMed ID: 37748445	2023
BCMA CAR-T cells in multiple myeloma-ready for take-off? Leukemia & lymphoma\| PubMed ID: 37997705	2024
Plain language summary of the CARTITUDE-4 study of ciltacabtagene autoleucel for the treatment of people with relapsed or refractory multiple myeloma. Future oncology (London, England)\| PubMed ID: 39110421	2024
Real-world treatment patterns and outcomes in relapsed/refractory multiple myeloma (1-3 prior lines): Flatiron database. Blood advances\| PubMed ID: 39110988	2024
Spatial transcriptomics reveals profound subclonal heterogeneity and T-cell dysfunction in extramedullary myeloma. Blood\| PubMed ID: 39172759	2024
Venetoclax-based salvage therapy as bridge-to-transplant is feasible and effective in patients with relapsed/refractory AML. Blood advances\| PubMed ID: 39293081	2024