Melissa Kirigiti

Division of Metabolic Health and Disease, Oregon National Primate Research Center

Affiliated withOregon National Primate Research Center

Research Area

Developmental Biology

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2024

Other Publications

Article	Year
Suppression of basal spontaneous gonadotropin-releasing hormone neuronal activity during lactation: role of inhibitory effects of neuropeptide Y. Endocrinology\| PubMed ID: 18719019	2009
Regulation of food intake and gonadotropin-releasing hormone/luteinizing hormone during lactation: role of insulin and leptin. Endocrinology\| PubMed ID: 19470705	2009
Early overnutrition results in early-onset arcuate leptin resistance and increased sensitivity to high-fat diet. Endocrinology\| PubMed ID: 20194730	2010
Differential gene expression between neuropeptide Y expressing neurons of the dorsomedial nucleus of the hypothalamus and the arcuate nucleus: microarray analysis study. Brain research\| PubMed ID: 20380814	2010
Characterisation of arcuate nucleus kisspeptin/neurokinin B neuronal projections and regulation during lactation in the rat. Journal of neuroendocrinology\| PubMed ID: 21029216	2011
Efferent projections of neuropeptide Y-expressing neurons of the dorsomedial hypothalamus in chronic hyperphagic models. The Journal of comparative neurology\| PubMed ID: 23172177	2013
Leptin stimulates neuropeptide Y and cocaine amphetamine-regulated transcript coexpressing neuronal activity in the dorsomedial hypothalamus in diet-induced obese mice. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 24048859	2013
Proinflammatory endothelial activation detected by molecular imaging in obese nonhuman primates coincides with onset of insulin resistance and progressively increases with duration of insuli... Circulation\| PubMed ID: 24163066	2014
Endogenous kisspeptin tone is a critical excitatory component of spontaneous GnRH activity and the GnRH response to NPY and CART. Neuroendocrinology\| PubMed ID: 25011649	2014
Developmental switch of leptin signaling in arcuate nucleus neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 25057200	2014
Expression and distribution of glucagon-like peptide-1 receptor mRNA, protein and binding in the male nonhuman primate (Macaca mulatta) brain. Endocrinology\| PubMed ID: 25380238	2015
Developmental changes in synaptic distribution in arcuate nucleus neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 26041922	2015
Maternal high-fat diet and obesity impact palatable food intake and dopamine signaling in nonhuman primate offspring. Obesity (Silver Spring, Md.)\| PubMed ID: 26530932	2015
GLP-1R Signaling Directly Activates Arcuate Nucleus Kisspeptin Action in Brain Slices but Does not Rescue Luteinizing Hormone Inhibition in Ovariectomized Mice During Negative Energy Balance... eNeuro\| PubMed ID: 28144621	2017
Maternal and postnatal high-fat diet consumption programs energy balance and hypothalamic melanocortin signaling in nonhuman primate offspring. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 28404581	2017
Arcuate nucleus neuropeptide coexpression and connections to gonadotrophin-releasing hormone neurones in the female rhesus macaque. Journal of neuroendocrinology\| PubMed ID: 28561903	2017
Early High-Fat Diet Exposure Causes Dysregulation of the Orexin and Dopamine Neuronal Populations in Nonhuman Primates. Frontiers in endocrinology\| PubMed ID: 30258403	2018
Central and Peripheral Administration of Fibroblast Growth Factor 1 Improves Pancreatic Islet Insulin Secretion in Diabetic Mouse Models. Diabetes\| PubMed ID: 31048370	2019
Reelin is modulated by diet-induced obesity and has direct actions on arcuate proopiomelanocortin neurons. Molecular metabolism\| PubMed ID: 31230943	2019
Effects of pre- and postnatal protein restriction on maternal and offspring metabolism in the nonhuman primate. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 32130027	2020
Cross-species analysis defines the conservation of anatomically segregated VMH neuron populations. eLife\| PubMed ID: 34018926	2021
Maternal Western-style diet in nonhuman primates leads to offspring islet adaptations including altered gene expression and insulin hypersecretion. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 37134140	2023
Suppression of food intake by Glp1r/Lepr-coexpressing neurons prevents obesity in mouse models. The Journal of clinical investigation\| PubMed ID: 37581939	2023
Analysis of beta-cell maturity and mitochondrial morphology in juvenile non-human primates exposed to maternal Western-style diet during development. Frontiers in endocrinology\| PubMed ID: 39114287	2024
Effect of metabolic status on response to SIV infection and antiretroviral therapy in nonhuman primates. JCI insight\| PubMed ID: 39115937	2024