Shuang Zhang

Department of Integration of Chinese and Western Medicine, Peking University

Affiliated withPeking University Chinese Academy of Medical Sciences & Peking Union Medical College Chinese Academy of Medical Sciences

Research Area

Biochemistry

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title	2024
Publication title Cited by 1	2026

Other Publications

Article	Year
A novel transdermal patch incorporating isosorbide dinitrate with bisoprolol: in vitro and in vivo characterization. International journal of pharmaceutics\| PubMed ID: 17267147	2007
[Clinicopathologic, immunohistochemical and molecular analysis in 15 cases of angioimmunoblastic T-cell lymphomas]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences\| PubMed ID: 18677379	2008
[Reassessment of the pathological diagnosis in 33 cases of malignant fibrous histiocytoma]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences\| PubMed ID: 18677383	2008
[Clinicopathologic study of hepatosplenic T-cell lymphoma]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences\| PubMed ID: 18677385	2008
[Differences of the molecular phenotypes and the histogenesis between dermatofibroma and dermatofibrosarcoma protuberans]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences\| PubMed ID: 18677387	2008
[Differential diagnosis of invasive ductal carcinoma versus invasive lobular carcinoma of breast]. Zhonghua bing li xue za zhi = Chinese journal of pathology\| PubMed ID: 20078969	2009
[Study on expression of natural killer (NK) cell C-type lectin-like receptors in nasal NK/T-cell lymphomas]. Zhonghua bing li xue za zhi = Chinese journal of pathology\| PubMed ID: 20654155	2010
[Expression of natural killer cell development-associated transcription factors in nasal NK/T-cell lymphomas occurring in Chinese population]. Zhonghua bing li xue za zhi = Chinese journal of pathology\| PubMed ID: 21055151	2010
Identification of dominant pathogens in periapical lesions associated with persistent apical periodontitis. The Chinese journal of dental research\| PubMed ID: 21264361	2010
Transcription factors engaged in development of NK cells are commonly expressed in nasal NK/T-cell lymphomas. Human pathology\| PubMed ID: 21329961	2011
[Histopathological features of hydatidiform moles and placenta changes of nonmolar miscarriage in early stage of pregnancy]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences\| PubMed ID: 21503111	2011
[Expression of microRNA in extranodal NK/T cell lymphoma, nasal type]. Zhonghua bing li xue za zhi Chinese journal of pathology\| PubMed ID: 22177245	2011
[Clinicopathologic and immunohistochemical study of 187 cases of intraductal papillary neoplasm of breast]. Zhonghua bing li xue za zhi Chinese journal of pathology\| PubMed ID: 22336153	2011
[Clinical and pathological analysis of three cases of childhood systemic EB virus positive T-cell lymphoproliferative disease]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences\| PubMed ID: 22898854	2012
Analysis of 142 Northern Chinese patients with peripheral T/NK-Cell lymphomas: subtype distribution, clinicopathologic features, and prognosis. American journal of clinical pathology\| PubMed ID: 22912362	2012
Clinicopathological classification and individualized treatment of breast cancer. Chinese medical journal\| PubMed ID: 24157157	2013
The downregulation of PRDM1/Blimp-1 is associated with aberrant expression of miR-223 in extranodal NK/T-cell lymphoma, nasal type. Journal of experimental & clinical cancer research : CR\| PubMed ID: 24438193	2014
Estrogen receptor α-coupled Bmi1 regulation pathway in breast cancer and its clinical implications. BMC cancer\| PubMed ID: 24559156	2014
Intratumoral heterogeneity of HER2 gene amplification in occult breast cancer. Chinese medical journal\| PubMed ID: 25316250	2014
[Evaluation and indication of human epithelial growth factor receptor 2 status in breast carcinoma with amplified chromosome]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences\| PubMed ID: 25331387	2014
Evaluation of the impact of passive smoke on arterial elasticity via echo-tracking technology in a rabbit model. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine\| PubMed ID: 25336482	2014
Adenomyoepithelioma of the breast with associated atypical lobular hyperplasia: a previously unrecognized association with management implications. Annals of diagnostic pathology\| PubMed ID: 25631879	2015
[Re-evaluation of HER2 status in 1 501 invasive breast cancers according to the 2013 American Society of Clinical Oncology/College of American Pathology guidelines]. Zhonghua bing li xue za zhi = Chinese journal of pathology\| PubMed ID: 25765030	2015
The antitumor activity of tumor-homing peptide-modified thermosensitive liposomes containing doxorubicin on MCF-7/ADR: in vitro and in vivo. International journal of nanomedicine\| PubMed ID: 25834435	2015
Comparative Analysis of Pharmacophore Features and Quantitative Structure-Activity Relationships for CD38 Covalent and Non-covalent Inhibitors. Chemical biology & drug design\| PubMed ID: 26072680	2015
Weber-Christian disease presenting with lung nodules dramatically improved with corticosteroid therapy: one case report and literature review. International journal of rheumatic diseases\| PubMed ID: 26224252	2018
Optimal threshold for stromal tumor-infiltrating lymphocytes: its predictive and prognostic value in HER2-positive breast cancer treated with trastuzumab-based neoadjuvant chemotherapy. Breast cancer research and treatment\| PubMed ID: 26498019	2015
Nuclear Gli1 expression is associated with pathological complete response and event-free survival in HER2-positive breast cancer treated with trastuzumab-based neoadjuvant therapy. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine\| PubMed ID: 26526577	2016
Tumor-specific pH-responsive peptide-modified pH-sensitive liposomes containing doxorubicin for enhancing glioma targeting and anti-tumor activity. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 26682502	2016
[Analysis on clinical and pathological characteristics of 66 patients with stage IV breast cancer]. Zhonghua wai ke za zhi [Chinese journal of surgery]\| PubMed ID: 26850666	2015
[Predictive factors of pathological complete response in primary human epidermal growth factor receptor 2-positive breast cancer treated with trastuzumab-based neoadjuvant chemotherapy]. Zhonghua wai ke za zhi [Chinese journal of surgery]\| PubMed ID: 26876074	2016
Multi-targeting NGR-modified liposomes recognizing glioma tumor cells and vasculogenic mimicry for improving anti-glioma therapy. Oncotarget\| PubMed ID: 27283987	2016
The anti-tumor efficacy of 3-(2-Nitrophenyl) propionic acid-paclitaxel (NPPA-PTX): a novel paclitaxel bioreductive prodrug. Oncotarget\| PubMed ID: 27366947	2016
A self-assembling nanomedicine of conjugated linoleic acid-paclitaxel conjugate (CLA-PTX) with higher drug loading and carrier-free characteristic. Scientific reports\| PubMed ID: 27812039	2016
Improving anti-tumor activity of sorafenib tosylate by lipid- and polymer-coated nanomatrix. Drug delivery\| PubMed ID: 28165798	2017
An open-label, two-period comparative study on pharmacokinetics and safety of a combined ethinylestradiol/gestodene transdermal contraceptive patch. Drug design, development and therapy\| PubMed ID: 28331292	2017
Identification of Novel Vacuolin-1 Analogues as Autophagy Inhibitors by Virtual Drug Screening and Chemical Synthesis. Molecules (Basel, Switzerland)\| PubMed ID: 28555021	2017
Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses. eLife\| PubMed ID: 28594325	2017
The Clinicopathological Factors Associated with Disease Progression in Luminal A Breast Cancer and Characteristics of Metastasis: A Retrospective Study from A Single Center in China. Anticancer research\| PubMed ID: 28739751	2017
Electromagnetic reprogrammable coding-metasurface holograms. Nature communications\| PubMed ID: 28775295	2017
Docking field-based QSAR and pharmacophore studies on the substituted pyrimidine derivatives targeting HIV-1 reverse transcriptase. Chemical biology & drug design\| PubMed ID: 28816417	2018
A retrospective prognostic evaluation analysis using the 8th edition of American Joint Committee on Cancer (AJCC) cancer staging system for luminal A breast cancer. Chinese journal of cancer research = Chung-kuo yen cheng yen chiu\| PubMed ID: 28947867	2017
Improving Solubility and Oral Bioavailability of Febuxostat by Polymer-Coated Nanomatrix. AAPS PharmSciTech\| PubMed ID: 29079988	2018
Effect of XlogP and Hansen Solubility Parameters on Small Molecule Modified Paclitaxel Anticancer Drug Conjugates Self-Assembled into Nanoparticles. Bioconjugate chemistry\| PubMed ID: 29300459	2018
The theranostic efficiency of tumor-specific, pH-responsive, peptide-modified, liposome-containing paclitaxel and superparamagnetic iron oxide nanoparticles. International journal of nanomedicine\| PubMed ID: 29559778	2018
Validation of the CPS+EG and Neo-Bioscore staging systems after preoperative systemic therapy for breast cancer in a single center in China. Breast (Edinburgh, Scotland)\| PubMed ID: 29677568	2018
Tailoring MoS Valley-Polarized Photoluminescence with Super Chiral Near-Field. Advanced materials (Deerfield Beach, Fla.)\| PubMed ID: 29984556	2018
Psychological Status of Volunteers in a Phase I Clinical Trial Assessed by Symptom Checklist 90 (SCL-90) and Eysenck Personality Questionnaire (EPQ). Medical science monitor : international medical journal of experimental and clinical research\| PubMed ID: 30015333	2018
Anti-tumour activity of low molecular weight heparin doxorubicin nanoparticles for histone H1 high-expressive prostate cancer PC-3M cells. Journal of controlled release : official journal of the Controlled Release Society\| PubMed ID: 30582952	2019
Antitumor activity of the bioreductive prodrug 3-(2-nitrophenyl) propionic acid-paclitaxel nanoparticles (NPPA-PTX NPs) on MDA-MB-231 cells: in vitro and in vivo. International journal of nanomedicine\| PubMed ID: 30636872	2019
Rapid depletion of ESCRT protein Vps4 underlies injury-induced autophagic impediment and Wallerian degeneration. Science advances\| PubMed ID: 30788439	2019
The influence of diet upon liver function indices of healthy volunteers resident in a Phase I clinical trail. American journal of translational research\| PubMed ID: 31217888	2019
Risk Factors for Dry Eye in Mainland China: A Multi-Center Cross-Sectional Hospital-Based Study. Ophthalmic epidemiology\| PubMed ID: 31218906	2019
Pharmacokinetics and Safety of Posaconazole Administered by Intravenous Solution and Oral Tablet in Healthy Chinese Subjects and Effect of Food on Tablet Bioavailability. Clinical drug investigation\| PubMed ID: 31432392	2019
Degp degrades a wide range of substrate proteins in Escherichia coli under stress conditions. The Biochemical journal\| PubMed ID: 31738379	2019
Clinicopathologic analysis of 722 breast cancer patients who met the inclusion criteria of the TAILORx trial. Chinese medical journal\| PubMed ID: 31809316	2019
Primary sclerosing epithelioid fibrosarcoma of chest wall in a patient with breast cancer: a case report. International journal of clinical and experimental pathology\| PubMed ID: 31933753	2019
Prognostic value of tumor-infiltrating lymphocyte subtypes in residual tumors of patients with triple-negative breast cancer after neoadjuvant chemotherapy. Chinese medical journal\| PubMed ID: 32044815	2020
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Alirocumab in Healthy Chinese Subjects: A Randomized, Double-Blind, Placebo-Controlled, Ascending Single-Dose Study. American journal of cardiovascular drugs : drugs, devices, and other interventions\| PubMed ID: 32080823	2020
A Single- and Multiple-Dose Study to Evaluate the Pharmacokinetics of Fixed-Dose Grazoprevir/Elbasvir in Healthy Chinese Participants. Clinical pharmacology : advances and applications\| PubMed ID: 32104104	2020
Enhancing Anti-Tumor Activity of Sorafenib Mesoporous Silica Nanomatrix in Metastatic Breast Tumor and Hepatocellular Carcinoma via the Co-Administration with Flufenamic Acid. International journal of nanomedicine\| PubMed ID: 32214813	2020
Clinicopathological analysis of early-stage breast cancer patients that meet indications for genetic testing. Chinese journal of cancer research = Chung-kuo yen cheng yen chiu\| PubMed ID: 32410794	2020
Clinical consequences of herpes simplex virus DNA in donor corneas: Different prognosis and management of endothelial keratoplasty and deep anterior lamellar keratoplasty. Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology\| PubMed ID: 32554307	2020
Changing Epidemiology of Hepatitis A in China: Evidence From Three National Serological Surveys and the National Notifiable Disease Reporting System. Hepatology (Baltimore, Md.)\| PubMed ID: 32592242	2021
Cerebellar Neurocytoma with Excellent Response to Radiotherapy. World neurosurgery\| PubMed ID: 32593767	2020
Loss of endothelial cells in viral DNA-positive grafts after keratoplasty: a 2-year follow-up study. The British journal of ophthalmology\| PubMed ID: 33055089	2022
The incidence and influence of the donor corneas positive for herpesviridae DNA in keratoplasty. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie\| PubMed ID: 33097979	2020
Successful treatment of recurrent benign fibrous histiocytoma by complete surgical removal and appropriate ocular surface reconstruction: A case report. Medicine\| PubMed ID: 33126361	2020
Malignant acanthosis nigricans: a case report. BMC ophthalmology\| PubMed ID: 33187499	2020
Histo- and clinico-pathological analysis of a large series of triple-negative breast cancer in a single center in China: Evidences on necessity of histological subtyping and grading. Chinese journal of cancer research = Chung-kuo yen cheng yen chiu\| PubMed ID: 33223753	2020
Pathogenic Effects and Pathogenesis Processes in Murine Cytomegalovirus Infected Rat Corneal Endothelial Cells. Ocular immunology and inflammation\| PubMed ID: 33226275	2020
A Single- and Multiple-Dose Study To Characterize the Pharmacokinetics, Safety, and Tolerability of Imipenem and Relebactam in Healthy Chinese Participants. Antimicrobial agents and chemotherapy\| PubMed ID: 33288637	2021
IgG4 immunohistochemistry in Riedel's thyroiditis and the recommended criteria for diagnosis: A case series and literature review. Clinical endocrinology\| PubMed ID: 33301600	2021
Retrospective analysis of sentinel lymph node biopsy using methylene blue dye for early breast cancer. Chinese medical journal\| PubMed ID: 33522727	2021
Clinical practice guidelines for sentinel lymph node biopsy in patients with early-stage breast cancer: Chinese Society of Breast Surgery (CSBrS) practice guidelines 2021. Chinese medical journal\| PubMed ID: 33813512	2021
Autophagy-Mediated Clearance of Free Genomic DNA in the Cytoplasm Protects the Growth and Survival of Cancer Cells. Frontiers in oncology\| PubMed ID: 34123836	2021
A combination strategy based on an Au nanorod/doxorubicin gel via mild photothermal therapy combined with antigen-capturing liposomes and anti-PD-L1 agent promote a positive shift in the can... Acta biomaterialia\| PubMed ID: 34619371	2021
Optimization of bifunctional piperidinamide derivatives as σR Antagonists/MOR agonists for treating neuropathic pain. European journal of medicinal chemistry\| PubMed ID: 34628236	2021
Establishing an Animal Model of Cytomegalovirus Keratouveitis in Rats: Broad Infection of Anterior Segment Tissue by Cytomegalovirus. Investigative ophthalmology & visual science\| PubMed ID: 34698772	2021
Circulating microRNAs as indicators in the prediction of neoadjuvant chemotherapy response in luminal B breast cancer. Thoracic cancer\| PubMed ID: 34751517	2021
Prognostic value of residual cancer burden and Miller-Payne system after neoadjuvant chemotherapy for breast cancer. Gland surgery\| PubMed ID: 35070881	2021
Androgen Receptor: A New Marker to Predict Pathological Complete Response in HER2-Positive Breast Cancer Patients Treated with Trastuzumab Plus Pertuzumab Neoadjuvant Therapy. Journal of personalized medicine\| PubMed ID: 35207749	2022
Eliciting national and subnational sets of disability weights in mainland China: Findings from the Chinese disability weight measurement study. The Lancet regional health. Western Pacific\| PubMed ID: 35910433	2022
Benzylaminofentanyl derivates: Discovery of bifunctional μ opioid and σ receptor ligands as novel analgesics with reduced adverse effects. European journal of medicinal chemistry\| PubMed ID: 35961067	2022
Expression of SASP, DNA Damage Response, and Cell Proliferation Factors in Early Gastric Neoplastic Lesions: Correlations and Clinical Significance. Pathology oncology research : POR\| PubMed ID: 36061145	2022
Endometrial squamous cell carcinoma originating from the cervix: A case report. World journal of clinical cases\| PubMed ID: 36157822	2022
Antitumor Activity of the Zinc Oxide Nanoparticles Coated with Low-Molecular-Weight Heparin and Doxorubicin Complex and . Molecular pharmaceutics\| PubMed ID: 36223494	2022
Correlation between Androgen Receptor Expression in Luminal B (HER-2 Negative) Breast Cancer and Disease Outcomes. Journal of personalized medicine\| PubMed ID: 36556209	2022
Alphaherpesvirus upregulates NDRG1 expression to facilitate the nuclear import of viral UL31 and UL34 proteins. Journal of medical virology\| PubMed ID: 36807585	2023
Clinical characteristics and surgical outcomes in children with mild malformation of cortical development and oligodendroglial hyperplasia in epilepsy. Epilepsia open\| PubMed ID: 37144544	2023
Analysis of clinicopathological characteristics and prognostic factors of early-stage human epidermal growth factor receptor 2 (HER2)-low breast cancer: Compared with HER2-0 breast cancer. Cancer medicine\| PubMed ID: 37772432	2023
Refined Qingkailing protects the in vitro neurovascular unit against oxygen-glucose deprivation and re-oxygenation-induced injury. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 37776640	2023
Effectiveness of dyadic sensory art therapies for People with dementia and their caregivers:A systematic review and meta-analysis. Geriatric nursing (New York, N.Y.)\| PubMed ID: 37782974	2023
Epilepsy Outcome and Pathology Analysis for Ganglioglioma: A Series of 51 Pediatric Patients. Pediatric neurology\| PubMed ID: 37879136	2023
A multicenter study on efficacy of dual-target neoadjuvant therapy for HER2-positive breast cancer and a consistent analysis of efficacy evaluation of neoadjuvant therapy by Miller-Payne and... Chinese journal of cancer research = Chung-kuo yen cheng yen chiu\| PubMed ID: 38204446	2023
Analysis of PIK3CA mutations in the primary and recurrent tumors of hormone receptor positive/human epidermal growth factor receptor 2 negative breast cancer. Japanese journal of clinical oncology\| PubMed ID: 38884134	2024
Angong Niuhuang Wan ameliorates LPS-induced cerebrovascular edema by inhibiting blood‒brain barrier leakage and promoting the membrane expression of AQP4. Frontiers in pharmacology\| PubMed ID: 39148543	2024
Comparative study of lung cancer between smokers and nonsmokers: A real-world study based on the whole population from Tianjin City, China. Tobacco induced diseases\| PubMed ID: 39253306	2024
Irinotecan hydrochloride liposome HR070803 in combination with 5-fluorouracil and leucovorin in locally advanced or metastatic pancreatic ductal adenocarcinoma following prior gemcitabine-ba... Signal transduction and targeted therapy\| PubMed ID: 39300077	2024
Proposal of a revised 3-tier "2 mm" risk classification model for postoperative pancreatic fistula in robotic pancreatoduodenectomy. Surgical endoscopy\| PubMed ID: 39390232	2024
Assessment of the internal genes of influenza A (H7N9) virus contributing to high pathogenicity in mice. Journal of virology\| PubMed ID: 25320305	2015
Cationic nanocarriers induce cell necrosis through impairment of Na(+)/K(+)-ATPase and cause subsequent inflammatory response. Cell research\| PubMed ID: 25613571	2015
Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles. Cell research\| PubMed ID: 27167569	2016
Rapid generation of functional hepatocyte-like cells from human adipose-derived stem cells. Stem cell research & therapy\| PubMed ID: 27495937	2016
Human Adipose-Derived Mesenchymal Stem Cell-Secreted CXCL1 and CXCL8 Facilitate Breast Tumor Growth By Promoting Angiogenesis. Stem cells (Dayton, Ohio)\| PubMed ID: 28514506	2017
Allelic frequency differences of variants between Caucasians and Asians and their association with major mood disorders. Signal transduction and targeted therapy\| PubMed ID: 31637017	2019
Comparison of Low-Density Lipoprotein Cholesterol (LDL-C) Goal Achievement and Lipid-Lowering Therapy in the Patients With Coronary Artery Disease With Different Renal Functions. Frontiers in cardiovascular medicine\| PubMed ID: 35620524	2022
The Prognostic Value of Cardiac Troponin I in Patients with or without Three-Vessel Disease Undergoing Complete Percutaneous Coronary Intervention. Journal of clinical medicine\| PubMed ID: 35807181	2022
Rationale and design of a randomized controlled trial: The effect of intensive lipid-lowering therapy with PCSK9 inhibitor on endothelial-coverage of stent strut after percutaneous coronary ... Heliyon\| PubMed ID: 38045163	2023
LDL-C rebound after long-term evolocumab treatment and intravascular imaging evidence in a familial hypercholesterolemia patient with early-onset myocardial infarction. Chronic diseases and translational medicine\| PubMed ID: 38450306	2024
The effect of lipid-lowering therapy on lipid-related residual risk factors: a prospective study. Lipids in health and disease\| PubMed ID: 38715079	2024
A comprehensive analysis of GAS2 family members identifies that GAS2L1 is a novel biomarker and promotes the proliferation of hepatocellular carcinoma. Discover oncology\| PubMed ID: 38858234	2024
Intestinal Nogo-B reduces GLP1 levels by binding to proglucagon on the endoplasmic reticulum to inhibit PCSK1 cleavage. Nature communications\| PubMed ID: 39122737	2024
Nogo-B inhibition facilitates cholesterol metabolism to reduce hypercholesterolemia. Cell reports\| PubMed ID: 39235944	2024
Publisher Correction: Intestinal Nogo-B reduces GLP1 levels by binding to proglucagon on the endoplasmic reticulum to inhibit PCSK1 cleavage. Nature communications\| PubMed ID: 39256382	2024
Effects of Different Bowel Preparation Regimens and Age Factors on the Gut Microbiota: A Prospective Randomized Controlled Study. Journal of gastroenterology and hepatology\| PubMed ID: 39778910	2025
ACSS2 protects against alcohol-induced hepatocyte ferroptosis through regulation of hepcidin expression. Nature communications\| PubMed ID: 40593779	2025
IMM-H007 promotes hepatic cholesterol and triglyceride metabolism by activating AMPK to attenuate hypercholesterolemia. Acta pharmaceutica Sinica. B\| PubMed ID: 40893685	2025
Humoral Immune Response to Inactivated SARS-CoV-2 Vaccine in Populations With and Without Prior COVID-19 Infection: A Longitudinal Cohort Study. Viral immunology\| PubMed ID: 40905942	2025
A multifunctional injectable nanocomposite hydrogel for precision keloid therapy via ECM remodeling and local pruritus relief. Journal of nanobiotechnology\| PubMed ID: 41580833	2026