Jen Q. Pan

Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard

Affiliated withBroad Institute of MIT and Harvard

Research Area

Neuroscience

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2024

Other Publications

Article	Year
Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis. Cell\| PubMed ID: 25748654	2015
Reduced Sleep Spindles in Schizophrenia: A Treatable Endophenotype That Links Risk Genes to Impaired Cognition? Biological psychiatry\| PubMed ID: 26602589	2016
Functionally Biased D2R Antagonists: Targeting the β-Arrestin Pathway to Improve Antipsychotic Treatment. ACS chemical biology\| PubMed ID: 29485852	2018
Developing High-Throughput Assays to Analyze and Screen Electrophysiological Phenotypes. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29736723	2018
Comprehensive comparative analysis of 5'-end RNA-sequencing methods. Nature methods\| PubMed ID: 29867192	2018
Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons. Nature biomedical engineering\| PubMed ID: 30271673	2018
Author Correction: Comprehensive comparative analysis of 5'-end RNA-sequencing methods. Nature methods\| PubMed ID: 30459407	2018
Effects of a patient-derived de novo coding alteration of CACNA1I in mice connect a schizophrenia risk gene with sleep spindle deficits. Translational psychiatry\| PubMed ID: 32066662	2020
Selective inhibition of glycogen synthase kinase 3α corrects pathophysiology in a mouse model of fragile X syndrome. Science translational medicine\| PubMed ID: 32434848	2020
Neurogranin, Encoded by the Schizophrenia Risk Gene NRGN, Bidirectionally Modulates Synaptic Plasticity via Calmodulin-Dependent Regulation of the Neuronal Phosphoproteome. Biological psychiatry\| PubMed ID: 33032807	2021
Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity. Genome biology\| PubMed ID: 33663567	2021
Novel Fluorescence-Based High-Throughput FLIPR Assay Utilizing Membrane-Tethered Genetic Calcium Sensors to Identify T-Type Calcium Channel Modulators. ACS pharmacology & translational science\| PubMed ID: 35311021	2022
AKT inhibition in the central nervous system induces signaling defects resulting in psychiatric symptomatology. Cell & bioscience\| PubMed ID: 35525984	2022
Non-rapid eye movement sleep and wake neurophysiology in schizophrenia. eLife\| PubMed ID: 35578829	2022
Mouse mutants in schizophrenia risk genes GRIN2A and AKAP11 show EEG abnormalities in common with schizophrenia patients. Translational psychiatry\| PubMed ID: 36914641	2023
IntelliSleepScorer, a software package with a graphic user interface for automated sleep stage scoring in mice based on a light gradient boosting machine algorithm. Scientific reports\| PubMed ID: 36922536	2023
Scanning mutagenesis of the voltage-gated sodium channel Na1.2 using base editing. Cell reports\| PubMed ID: 37267104	2023
A Potential Source of Bias in Group-Level EEG Microstate Analysis. Brain topography\| PubMed ID: 37548801	2024
Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice. Neuron\| PubMed ID: 37657442	2023
Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction. American journal of human genetics\| PubMed ID: 37802044	2023
A spectrum of altered non-rapid eye movement sleep in schizophrenia. bioRxiv : the preprint server for biology\| PubMed ID: 38234726	2023
Differential functional consequences of GRIN2A mutations associated with schizophrenia and neurodevelopmental disorders. Scientific reports\| PubMed ID: 38307912	2024
Study Protocol: Global Research Initiative on the Neurophysiology of Schizophrenia (GRINS) project. BMC psychiatry\| PubMed ID: 38858652	2024
Electroencephalographic Microstates During Sleep and Wake in Schizophrenia. Biological psychiatry global open science\| PubMed ID: 39296796	2024
A spectrum of altered non-rapid eye movement sleep in schizophrenia. Sleep\| PubMed ID: 39297495	2024