Sabine Hombach-Klonisch

Department of Human Anatomy and Cell Sciences, University of Manitoba

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2024

Other Publications

Article	Year
Human medullary thyroid carcinoma: a source and potential target for relaxin-like hormones. Annals of the New York Academy of Sciences\| PubMed ID: 15956746	2005
Relaxin downregulates the calcium binding protein S100A4 in MDA-MB-231 human breast cancer cells. Annals of the New York Academy of Sciences\| PubMed ID: 15956747	2005
INSL3 in the benign hyperplastic and neoplastic human prostate gland. International journal of oncology\| PubMed ID: 16010410	2005
The roe deer as a model for studying seasonal regulation of testis function. International journal of andrology\| PubMed ID: 16371113	2006
Dioxin exerts anti-estrogenic actions in a novel dioxin-responsive telomerase-immortalized epithelial cell line of the porcine oviduct (TERT-OPEC). Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 16431846	2006
Relaxin enhances the oncogenic potential of human thyroid carcinoma cells. The American journal of pathology\| PubMed ID: 16877360	2006
Relaxin-like ligand-receptor systems are autocrine/paracrine effectors in tumor cells and modulate cancer progression and tissue invasiveness. Advances in experimental medicine and biology\| PubMed ID: 18161484	2007
A mouse model of human mucopolysaccharidosis IX exhibits osteoarthritis. Human molecular genetics\| PubMed ID: 18344557	2008
Cancer stem cells as targets for cancer therapy: selected cancers as examples. Archivum immunologiae et therapiae experimentalis\| PubMed ID: 18512024	2008
Adult stem cells and their trans-differentiation potential--perspectives and therapeutic applications. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 18629466	2008
Relaxin reduces xenograft tumour growth of human MDA-MB-231 breast cancer cells. Breast cancer research : BCR\| PubMed ID: 18718015	2008
Cancer stem cell markers in common cancers - therapeutic implications. Trends in molecular medicine\| PubMed ID: 18775674	2008
INSL3 has tumor-promoting activity in thyroid cancer. International journal of cancer\| PubMed ID: 19950223	2010
Thyroid stem cells and cancer. Thyroid : official journal of the American Thyroid Association\| PubMed ID: 20001714	2009
Nuclear imaging in three dimensions: a unique tool in cancer research. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft\| PubMed ID: 20800459	2010
Estrogen-independent actions of environmentally relevant AhR-agonists in human endometrial epithelial cells. Molecular human reproduction\| PubMed ID: 20876610	2011
INSL5 is a novel marker for human enteroendocrine cells of the large intestine and neuroendocrine tumours. Oncology reports\| PubMed ID: 23128569	2013
Murine hyaluronidase 2 deficiency results in extracellular hyaluronan accumulation and severe cardiopulmonary dysfunction. The Journal of biological chemistry\| PubMed ID: 23172227	2013
Peri-conceptional changes in maternal exposure to sewage sludge chemicals disturbs fetal thyroid gland development in sheep. Molecular and cellular endocrinology\| PubMed ID: 23291342	2013
HMGA2 inhibits apoptosis through interaction with ATR-CHK1 signaling complex in human cancer cells. Neoplasia (New York, N.Y.)\| PubMed ID: 23479505	2013
Three-dimensional nuclear telomere architecture changes during endometrial carcinoma development. Genes, chromosomes & cancer\| PubMed ID: 23630056	2013
Three-dimensional telomere dynamics in follicular thyroid cancer. Thyroid : official journal of the American Thyroid Association\| PubMed ID: 23819464	2014
C1q-tumour necrosis factor-related protein 8 (CTRP8) is a novel interaction partner of relaxin receptor RXFP1 in human brain cancer cells. The Journal of pathology\| PubMed ID: 24014093	2013
Elevated urinary CCL2: Cr at 6 months is associated with renal allograft interstitial fibrosis and inflammation at 24 months. Transplantation\| PubMed ID: 24646773	2014
Mechanisms of therapeutic resistance in cancer (stem) cells with emphasis on thyroid cancer cells. Frontiers in endocrinology\| PubMed ID: 24723911	2014
Gesture-controlled interactive three dimensional anatomy: a novel teaching tool in head and neck surgery. Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale\| PubMed ID: 25286966	2014
Platinum (IV) coiled coil nanotubes selectively kill human glioblastoma cells. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 25680541	2015
RAGE Mediates the Pro-Migratory Response of Extracellular S100A4 in Human Thyroid Cancer Cells. Thyroid : official journal of the American Thyroid Association\| PubMed ID: 25744544	2015
RXFP1 is Targeted by Complement C1q Tumor Necrosis Factor-Related Factor 8 in Brain Cancer. Frontiers in endocrinology\| PubMed ID: 26322020	2015
High Mobility Group A2 protects cancer cells against telomere dysfunction. Oncotarget\| PubMed ID: 26799419	2016
Biodistribution of negatively charged iron oxide nanoparticles (IONPs) in mice and enhanced brain delivery using lysophosphatidic acid (LPA). Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 27125435	2016
Structural commonality of C1q TNF-related proteins and their potential to activate relaxin/insulin-like family peptide receptor 1 signalling pathways in cancer cells. British journal of pharmacology\| PubMed ID: 27443788	2017
Population-based analysis of breast cancer treatment by intrinsic sub-type in Manitoba, Canada. Cancer epidemiology\| PubMed ID: 27770672	2016
Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells. Scientific reports\| PubMed ID: 28344327	2017
Dovitinib enhances temozolomide efficacy in glioblastoma cells. Molecular oncology\| PubMed ID: 28500786	2017
Glioblastoma and chemoresistance to alkylating agents: Involvement of apoptosis, autophagy, and unfolded protein response. Pharmacology & therapeutics\| PubMed ID: 29080702	2018
Autophagy modulates transforming growth factor beta 1 induced epithelial to mesenchymal transition in non-small cell lung cancer cells. Biochimica et biophysica acta. Molecular cell research\| PubMed ID: 29481833	2018
C1q/TNF-related peptide 8 (CTRP8) promotes temozolomide resistance in human glioblastoma. Molecular oncology\| PubMed ID: 29949238	2018
HMGA2 as a functional antagonist of PARP1 inhibitors in tumor cells. Molecular oncology\| PubMed ID: 30289618	2019
Maternal smoking and high BMI disrupt thyroid gland development. BMC medicine\| PubMed ID: 30348172	2018
Statins: a new approach to combat temozolomide chemoresistance in glioblastoma. Journal of investigative medicine : the official publication of the American Federation for Clinical Research\| PubMed ID: 30368483	2018
A radial microfluidic platform for higher throughput chemotaxis studies with individual gradient control. Lab on a chip\| PubMed ID: 30427358	2018
Claudin 1 Is Highly Upregulated by PKC in MCF7 Human Breast Cancer Cells and Correlates Positively with PKCε in Patient Biopsies. Translational oncology\| PubMed ID: 30658316	2019
Unlocking bone for proteomic analysis and FISH. Laboratory investigation; a journal of technical methods and pathology\| PubMed ID: 30659273	2019
Emerging roles for the relaxin/RXFP1 system in cancer therapy. Molecular and cellular endocrinology\| PubMed ID: 30763603	2019
Simvastatin increases temozolomide-induced cell death by targeting the fusion of autophagosomes and lysosomes. The FEBS journal\| PubMed ID: 31545550	2019
Modulation of Wnt/β-catenin signaling promotes blood-brain barrier phenotype in cultured brain endothelial cells. Scientific reports\| PubMed ID: 31873116	2019
Novel CTRP8-RXFP1-JAK3-STAT3 axis promotes Cdc42-dependent actin remodeling for enhanced filopodia formation and motility in human glioblastoma cells. Molecular oncology\| PubMed ID: 33960104	2022
Slow Off-Rate Modified Aptamer (SOMAmer) Proteomic Analysis of Patient-Derived Malignant Glioma Identifies Distinct Cellular Proteomes. International journal of molecular sciences\| PubMed ID: 34502484	2021
The Breast Tumor Microenvironment: A Key Player in Metastatic Spread. Cancers\| PubMed ID: 34638283	2021
Brain Microvascular Pericytes-More than Bystanders in Breast Cancer Brain Metastasis. Cells\| PubMed ID: 35455945	2022
Nuclear High Mobility Group A2 (HMGA2) Interactome Revealed by Biotin Proximity Labeling. International journal of molecular sciences\| PubMed ID: 36835656	2023
Human C1q Tumor Necrosis Factor 8 (CTRP8) defines a novel tryptase+ mast cell subpopulation in the prostate cancer microenvironment. Biochimica et biophysica acta. Molecular basis of disease\| PubMed ID: 36921737	2023
Aberrant HMGA2 Expression Sustains Genome Instability That Promotes Metastasis and Therapeutic Resistance in Colorectal Cancer. Cancers\| PubMed ID: 36980621	2023
DUBing Primary Tumors of the Central Nervous System: Regulatory Roles of Deubiquitinases. Biomolecules\| PubMed ID: 37892185	2023
Breast Tumor Metastasis and Its Microenvironment: It Takes Both Seed and Soil to Grow a Tumor and Target It for Treatment. Cancers\| PubMed ID: 38473273	2024
Characterization of HMGA2 variants expands the spectrum of Silver-Russell syndrome. JCI insight\| PubMed ID: 38516887	2024
Overcoming brain-derived therapeutic resistance in HER2+ breast cancer brain metastasis. bioRxiv : the preprint server for biology\| PubMed ID: 38529509	2024
C1QTNF Related protein 8 (CTRP8) is a marker of myeloid derived innate immune cell populations in the human breast cancer microenvironment. Biochemical pharmacology\| PubMed ID: 39542181	2024