Yue Lu

Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center

Affiliated withUniversity of Texas MD Anderson Cancer Center

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2024

Other Publications

Article	Year
Molecular mechanism by which the nucleoid occlusion factor, SlmA, keeps cytokinesis in check. The EMBO journal\| PubMed ID: 21113127	2011
TDRD3 is an effector molecule for arginine-methylated histone marks. Molecular cell\| PubMed ID: 21172665	2010
Aberrant DNA methylation is associated with disease progression, resistance to imatinib and shortened survival in chronic myelogenous leukemia. PloS one\| PubMed ID: 21760961	2011
Dnmt3a is essential for hematopoietic stem cell differentiation. Nature genetics\| PubMed ID: 22138693	2012
SINE retrotransposons cause epigenetic reprogramming of adjacent gene promoters. Molecular cancer research : MCR\| PubMed ID: 22952045	2012
dsPIG: a tool to predict imprinted genes from the deep sequencing of whole transcriptomes. BMC bioinformatics\| PubMed ID: 23083219	2012
Stabilization of the promoter nucleosomes in nucleosome-free regions by the yeast Cyc8-Tup1 corepressor. Genome research\| PubMed ID: 23124522	2013
The epigenome of AML stem and progenitor cells. Epigenetics\| PubMed ID: 23249680	2013
Accuracy of RNA-Seq and its dependence on sequencing depth. BMC bioinformatics\| PubMed ID: 23320920	2012
Architecture of epigenetic reprogramming following Twist1-mediated epithelial-mesenchymal transition. Genome biology\| PubMed ID: 24367927	2013
Age-related epigenetic drift in the pathogenesis of MDS and AML. Genome research\| PubMed ID: 24414704	2014
Arginine methylation facilitates the recruitment of TOP3B to chromatin to prevent R loop accumulation. Molecular cell\| PubMed ID: 24507716	2014
Integrated genetic approaches identify the molecular mechanisms of Sox4 in early B-cell development: intricate roles for RAG1/2 and CK1ε. Blood\| PubMed ID: 24786772	2014
The Sox4/Tcf7l1 axis promotes progression of BCR-ABL-positive acute lymphoblastic leukemia. Haematologica\| PubMed ID: 24997151	2014
The tumor promoting activity of the EP4 receptor for prostaglandin E2 in murine skin. Molecular oncology\| PubMed ID: 25034079	2014
Gcn5 and PCAF negatively regulate interferon-β production through HAT-independent inhibition of TBK1. EMBO reports\| PubMed ID: 25269644	2014
A role for BMP-induced homeobox gene MIXL1 in acute myelogenous leukemia and identification of type I BMP receptor as a potential target for therapy. Oncotarget\| PubMed ID: 25544748	2014
Tyrosine kinase inhibitors induce mesenchymal stem cell-mediated resistance in BCR-ABL+ acute lymphoblastic leukemia. Blood\| PubMed ID: 25712988	2015
TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia. Cancer research\| PubMed ID: 25972343	2015
Methylome sequencing for fibrolamellar hepatocellular carcinoma depicts distinctive features. Epigenetics\| PubMed ID: 26224146	2015
A Molecular Portrait of High-Grade Ductal Carcinoma In Situ. Cancer research\| PubMed ID: 26249178	2015
Defects of Lipid Synthesis Are Linked to the Age-Dependent Demyelination Caused by Lamin B1 Overexpression. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 26311780	2015
Epigenetic synergy between decitabine and platinum derivatives. Clinical epigenetics\| PubMed ID: 26366234	2015
Expanded GAA repeats impede transcription elongation through the FXN gene and induce transcriptional silencing that is restricted to the FXN locus. Human molecular genetics\| PubMed ID: 26401053	2015
LSD1 is essential for oocyte meiotic progression by regulating CDC25B expression in mice. Nature communications\| PubMed ID: 26626423	2015
Stem cell and neurogenic gene-expression profiles link prostate basal cells to aggressive prostate cancer. Nature communications\| PubMed ID: 26924072	2016
Defining a Population of Stem-like Human Prostate Cancer Cells That Can Generate and Propagate Castration-Resistant Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 27060154	2016
Maternal Setdb1 Is Required for Meiotic Progression and Preimplantation Development in Mouse. PLoS genetics\| PubMed ID: 27070551	2016
ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth. Molecular cell\| PubMed ID: 27132940	2016
DNA Methylation Signature Reveals Cell Ontogeny of Renal Cell Carcinomas. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 27256309	2016
Activation of HERV-K Env protein is essential for tumorigenesis and metastasis of breast cancer cells. Oncotarget\| PubMed ID: 27557521	2016
PHF20 Readers Link Methylation of Histone H3K4 and p53 with H4K16 Acetylation. Cell reports\| PubMed ID: 27760318	2016
Serum exosomal miR-4772-3p is a predictor of tumor recurrence in stage II and III colon cancer. Oncotarget\| PubMed ID: 27788488	2016
NANOG reprograms prostate cancer cells to castration resistance via dynamically repressing and engaging the AR/FOXA1 signaling axis. Cell discovery\| PubMed ID: 27867534	2016
A CpG island methylator phenotype in acute myeloid leukemia independent of IDH mutations and associated with a favorable outcome. Leukemia\| PubMed ID: 28074068	2017
MicroRNA-141 suppresses prostate cancer stem cells and metastasis by targeting a cohort of pro-metastasis genes. Nature communications\| PubMed ID: 28112170	2017
Developing a Novel Two-Dimensional Culture System to Enrich Human Prostate Luminal Progenitors that Can Function as a Cell of Origin for Prostate Cancer. Stem cells translational medicine\| PubMed ID: 28297567	2017
RNA sequencing analyses reveal novel differentially expressed genes and pathways in pancreatic cancer. Oncotarget\| PubMed ID: 28418924	2017
Analysis of DNA polymerase ν function in meiotic recombination, immunoglobulin class-switching, and DNA damage tolerance. PLoS genetics\| PubMed ID: 28570559	2017
Genetic deletion or small-molecule inhibition of the arginine methyltransferase PRMT5 exhibit anti-tumoral activity in mouse models of MLL-rearranged AML. Leukemia\| PubMed ID: 28663579	2018
Downregulation of Human Endogenous Retrovirus Type K (HERV-K) Viral RNA in Pancreatic Cancer Cells Decreases Cell Proliferation and Tumor Growth. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 28679769	2017
Transcriptional consequences of XPA disruption in human cell lines. DNA repair\| PubMed ID: 28704716	2017
Caloric restriction delays age-related methylation drift. Nature communications\| PubMed ID: 28912502	2017
Comprehensive analysis of gene expression patterns in Friedreich's ataxia fibroblasts by RNA sequencing reveals altered levels of protein synthesis factors and solute carriers. Disease models & mechanisms\| PubMed ID: 29125828	2017
Digital Restriction Enzyme Analysis of Methylation (DREAM). Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 29224148	2018
GCN5 Regulates FGF Signaling and Activates Selective MYC Target Genes during Early Embryoid Body Differentiation. Stem cell reports\| PubMed ID: 29249668	2018
Histone 2B-GFP Label-Retaining Prostate Luminal Cells Possess Progenitor Cell Properties and Are Intrinsically Resistant to Castration. Stem cell reports\| PubMed ID: 29276153	2018
Response to "XPA is primarily cytoplasmic but is transported into the nucleus upon UV damage". DNA repair\| PubMed ID: 29337160	2018
The arginine methyltransferase CARM1 represses p300•ACT•CREMτ activity and is required for spermiogenesis. Nucleic acids research\| PubMed ID: 29659998	2018
Deficient LRRC8A-dependent volume-regulated anion channel activity is associated with male infertility in mice. JCI insight\| PubMed ID: 30135305	2018
KDM6B overexpression activates innate immune signaling and impairs hematopoiesis in mice. Blood advances\| PubMed ID: 30275007	2018
Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 30297393	2018
DNMT3L facilitates DNA methylation partly by maintaining DNMT3A stability in mouse embryonic stem cells. Nucleic acids research\| PubMed ID: 30321403	2019
Mouse Models of Overexpression Reveal Distinct Oncogenic Roles for Different Type I Protein Arginine Methyltransferases. Cancer research\| PubMed ID: 30352814	2019
Combinations of Tyrosine Kinase Inhibitor and ERAD Inhibitor Promote Oxidative Stress-Induced Apoptosis through ATF4 and KLF9 in Medullary Thyroid Cancer. Molecular cancer research : MCR\| PubMed ID: 30552230	2019
USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta. Development (Cambridge, England)\| PubMed ID: 30718289	2019
Oncogenic and osteolytic functions of histone demethylase NO66 in castration-resistant prostate cancer. Oncogene\| PubMed ID: 30858546	2019
Structural basis of specific DNA binding by the transcription factor ZBTB24. Nucleic acids research\| PubMed ID: 31226215	2019
Systematic evaluation of RNA-Seq preparation protocol performance. BMC genomics\| PubMed ID: 31296163	2019
CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas. Leukemia\| PubMed ID: 32576962	2020
KRAB domain of ZFP568 disrupts TRIM28-mediated abnormal interactions in cancer cells. NAR cancer\| PubMed ID: 32743551	2020
Bone morphogenetic protein 7 promotes resistance to immunotherapy. Nature communications\| PubMed ID: 32973129	2020
Author Correction: Bone morphogenetic protein 7 promotes resistance to immunotherapy. Nature communications\| PubMed ID: 33033261	2020
Transcriptional Activation of MYC-Induced Genes by GCN5 Promotes B-cell Lymphomagenesis. Cancer research\| PubMed ID: 33168647	2020
Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas. Nature communications\| PubMed ID: 33514726	2021
ATF3-Induced Mammary Tumors Exhibit Molecular Features of Human Basal-Like Breast Cancer. International journal of molecular sciences\| PubMed ID: 33652981	2021
Resolution of tissue signatures of therapy response in patients with recurrent GBM treated with neoadjuvant anti-PD1. Nature communications\| PubMed ID: 34188042	2021
Overexpression Leads to Aberrant Signal Transduction of Cancer-Related Pathways but Is Not Sufficient to Drive Tumor Formation in Mice. Cancers\| PubMed ID: 34503086	2021
Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer. Nature communications\| PubMed ID: 34508101	2021
Identification of novel susceptibility methylation loci for pancreatic cancer in a two-phase epigenome-wide association study. Epigenetics\| PubMed ID: 35030986	2022
Methyl-lysine readers PHF20 and PHF20L1 define two distinct gene expression-regulating NSL complexes. The Journal of biological chemistry\| PubMed ID: 35033534	2022
Defining the mammalian coactivation of hepatic 12-h clock and lipid metabolism. Cell reports\| PubMed ID: 35263593	2022
Cooperation between KDM6B overexpression and TET2 deficiency in the pathogenesis of chronic myelomonocytic leukemia. Leukemia\| PubMed ID: 35697791	2022
CHD1 Promotes Sensitivity to Aurora Kinase Inhibitors by Suppressing Interaction of AURKA with Its Coactivator TPX2. Cancer research\| PubMed ID: 35771632	2022
Transcriptomic Signatures of Hypomethylating Agent Failure in Myelodysplastic Syndromes and Chronic Myelomonocytic Leukemia. Experimental hematology\| PubMed ID: 36150563	2022
The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer. Nature communications\| PubMed ID: 36690626	2023
WWOX P47T partial loss-of-function mutation induces epilepsy, progressive neuroinflammation, and cerebellar degeneration in mice phenocopying human SCAR12. Progress in neurobiology\| PubMed ID: 36828035	2023
Commercial ChIP-Seq Library Preparation Kits Performed Differently for Different Classes of Protein Targets. Journal of biomolecular techniques : JBT\| PubMed ID: 36910579	2022
Comparison of pharmacological inhibitors of lysine-specific demethylase 1 in glioblastoma stem cells reveals inhibitor-specific efficacy profiles. Frontiers in neurology\| PubMed ID: 37082446	2023
Cigarette smoke exposure accelerates AML progression in FLT3-ITD models. Blood advances\| PubMed ID: 37486624	2023
The AT-hook is an evolutionarily conserved auto-regulatory domain of SWI/SNF required for cell lineage priming. Nature communications\| PubMed ID: 37542049	2023
The SAGA acetyltransferase module is required for the maintenance of MAF and MYC oncogenic gene expression programs in multiple myeloma. bioRxiv : the preprint server for biology\| PubMed ID: 38585845	2024
The SAGA acetyltransferase module is required for the maintenance of MAF and MYC oncogenic gene expression programs in multiple myeloma. Genes & development\| PubMed ID: 39168636	2024
The ICF syndrome protein CDCA7 harbors a unique DNA binding domain that recognizes a CpG dyad in the context of a non-B DNA. Science advances\| PubMed ID: 39178265	2024
MTA-cooperative PRMT5 inhibitors enhance T cell-mediated antitumor activity in MTAP-loss tumors. Journal for immunotherapy of cancer\| PubMed ID: 39313308	2024
Stem cell activity-coupled suppression of endogenous retrovirus governs adult tissue regeneration. Cell\| PubMed ID: 39476839	2024