Anskar Leung

Department of Medicine, The University of Hong Kong

Affiliated withThe University of Hong Kong Hong Kong Science Park

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 5	2024

Other Publications

Article	Year
Proliferating cell nuclear antigen (PCNA) as a proliferative marker during embryonic and adult zebrafish hematopoiesis. Histochemistry and cell biology\| PubMed ID: 16028068	2005
Kinetics and risk of de novo hepatitis B infection in HBsAg-negative patients undergoing cytotoxic chemotherapy. Gastroenterology\| PubMed ID: 16831590	2006
All-trans retinoic acid induces proliferation of an irradiated stem cell supporting stromal cell line AFT024. Experimental hematology\| PubMed ID: 17198874	2007
Safety of vaccinating sibling donors with live-attenuated varicella zoster vaccine before hematopoietic stem cell transplantation. Bone marrow transplantation\| PubMed ID: 17417658	2007
A novel zebrafish jak2a(V581F) model shared features of human JAK2(V617F) polycythemia vera. Experimental hematology\| PubMed ID: 19772888	2009
Successful engraftment by leukemia initiating cells in adult acute lymphoblastic leukemia after direct intrahepatic injection into unconditioned newborn NOD/SCID mice. Experimental hematology\| PubMed ID: 19837128	2010
Differential NOD/SCID mouse engraftment of peripheral blood CD34+ cells and JAK2V617F clones from patients with myeloproliferative neoplasms. Leukemia research\| PubMed ID: 20170959	2010
Sweet Syndrome due to Myelodysplastic Syndrome: Possible Therapeutic Role of Intravenous Immunoglobulin in Addition to Standard Treatment. Advances in hematology\| PubMed ID: 20369066	2010
Metabolic activity measured by F-18 FDG PET in natural killer-cell lymphoma compared to aggressive B- and T-cell lymphomas. Clinical nuclear medicine\| PubMed ID: 20631501	2010
Role of a novel zebrafish nup98 during embryonic development. Experimental hematology\| PubMed ID: 20696206	2010
Whole-body diffusion-weighted imaging: the added value to whole-body MRI at initial diagnosis of lymphoma. AJR. American journal of roentgenology\| PubMed ID: 21862763	2011
Methionine aminopeptidase 2 is required for HSC initiation and proliferation. Blood\| PubMed ID: 21937698	2011
Post-genome wide association studies and functional analyses identify association of MPP7 gene variants with site-specific bone mineral density. Human molecular genetics\| PubMed ID: 22171069	2012
Sorafenib treatment of FLT3-ITD(+) acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation. Blood\| PubMed ID: 22368270	2012
Quantification of BK viral load in asymptomatic renal allograft recipients. Renal failure\| PubMed ID: 22390257	2012
CFTR mediates bicarbonate-dependent activation of miR-125b in preimplantation embryo development. Cell research\| PubMed ID: 22664907	2012
A simple, cost-effective but highly efficient system for deriving ventricular cardiomyocytes from human pluripotent stem cells. Stem cells and development\| PubMed ID: 24564569	2014
Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia. Blood\| PubMed ID: 24591202	2014
A novel tescalcin-sodium/hydrogen exchange axis underlying sorafenib resistance in FLT3-ITD+ AML. Blood\| PubMed ID: 24608976	2014
Antioxidant N-acetyl-L-cysteine increases engraftment of human hematopoietic stem cells in immune-deficient mice. Blood\| PubMed ID: 25287706	2014
Functions of idh1 and its mutation in the regulation of developmental hematopoiesis in zebrafish. Blood\| PubMed ID: 25778530	2015
Azacitidine as post-remission consolidation for sorafenib-induced remission of Fms-like tyrosine kinase-3 internal tandem duplication positive acute myeloid leukemia. Haematologica\| PubMed ID: 25820334	2015
A dynamic model of chemoattractant-induced cell migration. Biophysical journal\| PubMed ID: 25863056	2015
Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia. Blood\| PubMed ID: 25940713	2015
Fluorescent Probe HKSOX-1 for Imaging and Detection of Endogenous Superoxide in Live Cells and In Vivo. Journal of the American Chemical Society\| PubMed ID: 25988218	2015
Fishing the targets of myeloid malignancies in the era of next generation sequencing. Blood reviews\| PubMed ID: 26443083	2016
Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors. Nature medicine\| PubMed ID: 26594843	2015
Pim kinases modulate resistance to FLT3 tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia. Science advances\| PubMed ID: 26601252	2015
Cell adhesion manipulation through single cell assembly for characterization of initial cell-to-cell interaction. Biomedical engineering online\| PubMed ID: 26652601	2015
Molecular and Cellular Mechanisms of Myelodysplastic Syndrome: Implications on Targeted Therapy. International journal of molecular sciences\| PubMed ID: 27023522	2016
Homoharringtonine (omacetaxine mepesuccinate) as an adjunct for FLT3-ITD acute myeloid leukemia. Science translational medicine\| PubMed ID: 27708062	2016
INDELseek: detection of complex insertions and deletions from next-generation sequencing data. BMC genomics\| PubMed ID: 28056804	2017
FLT3 inhibitors: clinical potential in acute myeloid leukemia. OncoTargets and therapy\| PubMed ID: 28223820	2017
A Zebrafish Model for Evaluating the Function of Human Leukemic Gene IDH1 and Its Mutation. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 28735489	2017
Treatment of acute myeloid leukemia in the next decade - Towards real-time functional testing and personalized medicine. Blood reviews\| PubMed ID: 28797519	2017
Integrating Functional Analysis in the Next-Generation Sequencing Diagnostic Pipeline of RASopathies. Scientific reports\| PubMed ID: 29402968	2018
Efficient RNA drug delivery using red blood cell extracellular vesicles. Nature communications\| PubMed ID: 29907766	2018
Quizartinib versus salvage chemotherapy in relapsed or refractory FLT3-ITD acute myeloid leukaemia (QuANTUM-R): a multicentre, randomised, controlled, open-label, phase 3 trial. The Lancet. Oncology\| PubMed ID: 31175001	2019
Sorafenib and omacetaxine mepesuccinate as a safe and effective treatment for acute myeloid leukemia carrying internal tandem duplication of Fms-like tyrosine kinase 3. Cancer\| PubMed ID: 31580501	2020
Diverse pathogenetic roles of SOX genes in acute myeloid leukaemia and their therapeutic implications. Seminars in cancer biology\| PubMed ID: 31698089	2020
Overcoming Resistance to FLT3 Inhibitors in the Treatment of -Mutated AML. International journal of molecular sciences\| PubMed ID: 32102366	2020
Follistatin is a novel therapeutic target and biomarker in FLT3/ITD acute myeloid leukemia. EMBO molecular medicine\| PubMed ID: 32134197	2020
Function of Arl4aa in the Initiation of Hematopoiesis in Zebrafish by Maintaining Golgi Complex Integrity in Hemogenic Endothelium. Stem cell reports\| PubMed ID: 32220330	2020
Redefining prognostication of de novo cytogenetically normal acute myeloid leukemia in young adults. Blood cancer journal\| PubMed ID: 33077814	2020
Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia. Science translational medicine\| PubMed ID: 33627486	2021
High-fidelity KKH variant of Staphylococcus aureus Cas9 nucleases with improved base mismatch discrimination. Nucleic acids research\| PubMed ID: 35051997	2022
COVID-19 vaccines and risks of hematological abnormalities: Nested case-control and self-controlled case series study. American journal of hematology\| PubMed ID: 35080247	2022
Surface-engineered extracellular vesicles for targeted delivery of therapeutic RNAs and peptides for cancer therapy. Theranostics\| PubMed ID: 35547755	2022
Regulation of proton partitioning in kinase-activating acute myeloid leukemia and its therapeutic implication. Leukemia\| PubMed ID: 35624145	2022
Thromboembolic events and hemorrhagic stroke after mRNA (BNT162b2) and inactivated (CoronaVac) covid-19 vaccination: A self-controlled case series study. EClinicalMedicine\| PubMed ID: 35770253	2022
CD33-targeting extracellular vesicles deliver antisense oligonucleotides against FLT3-ITD and miR-125b for specific treatment of acute myeloid leukaemia. Cell proliferation\| PubMed ID: 35851970	2022
Pharmacogenomic Profiling of Pediatric Acute Myeloid Leukemia to Identify Therapeutic Vulnerabilities and Inform Functional Precision Medicine. Blood cancer discovery\| PubMed ID: 35960210	2022
Unravelling genetic causality of haematopoiesis on bone metabolism in human. European journal of endocrinology\| PubMed ID: 36201175	2022
Discrete single-cell microRNA analysis for phenotyping the heterogeneity of acute myeloid leukemia. Biomaterials\| PubMed ID: 36327706	2022
Transgenic IDH2 and IDH2 zebrafish models recapitulated features of human acute myeloid leukemia. Oncogene\| PubMed ID: 36739363	2023
Correction: Transgenic IDH2 and IDH2 zebrafish models recapitulated features of human acute myeloid leukemia. Oncogene\| PubMed ID: 36922683	2023
Pivotal role of cytosolic phospholipase PLA2G4A in the pathogenesis of -ITD-mutated acute myeloid leukemia. Genes & diseases\| PubMed ID: 37013044	2023
Unraveling the whole genome DNA methylation profile of zebrafish kidney marrow by Oxford Nanopore sequencing. Scientific data\| PubMed ID: 37563176	2023
Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML. Blood\| PubMed ID: 37738460	2023
Distinct karyotypic and mutational landscape in trisomy AML. British journal of haematology\| PubMed ID: 38054248	2024
Application of droplet digital PCR in minimal residual disease monitoring of rare fusion transcripts and mutations in haematological malignancies. Scientific reports\| PubMed ID: 38493200	2024
Microenvironment matters: In vitro 3D bone marrow niches differentially modulate survival, phenotype and drug responses of acute myeloid leukemia (AML) cells. Biomaterials\| PubMed ID: 39088912	2025
Roles of Setbp1 in developmental hematopoiesis and acute myeloid leukemia. Genes & diseases\| PubMed ID: 39104425	2024
Giraffe: A tool for comprehensive processing and visualization of multiple long-read sequencing data. Computational and structural biotechnology journal\| PubMed ID: 39279873	2024