Junrong Du

Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan University

Affiliated withSichuan University

Research Area

Biology

Biography

Junrong Du has not added Biography.
If you are Junrong Du and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
[Studies on therapeutic effects of zhenzhu qishi wan on stroke and hypertension of SHRsp]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica\| PubMed ID: 15015340	2003
[High cholesterol level upregulate the expression of caveolin-1]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi\| PubMed ID: 15143558	2004
[Antitumor effect of gene therapy with recombinant adenovirus-mediated human interleukin-2 gene transfer and its mechanism]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition\| PubMed ID: 15600167	2003
[The experimental study of the effect of tanshinone on artery restenosis in mouse]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica\| PubMed ID: 15706855	2004
Tanshinone inhibits intimal hyperplasia in the ligated carotid artery in mice. Journal of ethnopharmacology\| PubMed ID: 15814266	2005
[Influence of Xinqin tablets on guinea-pig nasal hypersensitivity]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica\| PubMed ID: 16075722	2005
[Experimental study of effect of tanshinone on artery restenosis in rat carotid injury model]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica\| PubMed ID: 16780164	2006
Neuroprotective effect of Z-ligustilide against permanent focal ischemic damage in rats. Biological & pharmaceutical bulletin\| PubMed ID: 17268071	2007
Protection against hydrogen peroxide-induced injury by Z-ligustilide in PC12 cells. Experimental brain research\| PubMed ID: 17717647	2008
Postischemic administration of Z-Ligustilide ameliorates cognitive dysfunction and brain damage induced by permanent forebrain ischemia in rats. Pharmacology, biochemistry, and behavior\| PubMed ID: 17889286	2008
Protective effect of Z-ligustilide against amyloid beta-induced neurotoxicity is associated with decreased pro-inflammatory markers in rat brains. Pharmacology, biochemistry, and behavior\| PubMed ID: 19324070	2009
Z-ligustilide extracted from Radix Angelica Sinensis decreased platelet aggregation induced by ADP ex vivo and arterio-venous shunt thrombosis in vivo in rats. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan\| PubMed ID: 19571521	2009
Modulation of Xiongdanjiuxin pills on the gut-liver axis in high-fat diet rats. Life sciences\| PubMed ID: 37778415	2023
[Antihypertensive effect and pharmacokinetics of low molecular mass potassium alginate]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition\| PubMed ID: 19764575	2009
Preventive effects of low molecular mass potassium alginate extracted from brown algae on DOCA salt-induced hypertension in rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 19932586	2010
[Effects of combined use of dofetilide and verapamil on the action potential of papillary muscles in guinea pigs]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition\| PubMed ID: 19950594	2009
[Pharmacological activities of Z-ligustilide and metabolites in rats]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition\| PubMed ID: 19950595	2009
Tanshinone IIA inhibits smooth muscle proliferation and intimal hyperplasia in the rat carotid balloon-injured model through inhibition of MAPK signaling pathway. Journal of ethnopharmacology\| PubMed ID: 20363310	2010
Z-ligustilide attenuates lipopolysaccharide-induced proinflammatory response via inhibiting NF-kappaB pathway in primary rat microglia. Acta pharmacologica Sinica\| PubMed ID: 20581853	2010
Aqueous extract of Gleditsia sinensis Lam. fruits improves serum and liver lipid profiles and attenuates atherosclerosis in rabbits fed a high-fat diet. Journal of ethnopharmacology\| PubMed ID: 21718773	2011
Z-ligustilide isolated from Radix Angelicae sinensis ameliorates the memory impairment induced by scopolamine in mice. Fitoterapia\| PubMed ID: 21807074	2011
Cardioprotective effect of water and ethanol extract of Salvia miltiorrhiza in an experimental model of myocardial infarction. Journal of ethnopharmacology\| PubMed ID: 22138518	2012
Formulation and evaluation of novel coated floating tablets of bergenin and cetirizine dihydrochloride for gastric delivery. Drug development and industrial pharmacy\| PubMed ID: 22206469	2012
[Protective effects of Z-ligustilide against cytotoxicity induced by Abeta25-35 in neuron cells]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition\| PubMed ID: 22455127	2012
Neuroprotective effect of kaempferol glycosides against brain injury and neuroinflammation by inhibiting the activation of NF-κB and STAT3 in transient focal stroke. PloS one\| PubMed ID: 23437066	2013
Klotho upregulation contributes to the neuroprotection of ligustilide in an Alzheimer's disease mouse model. Neurobiology of aging\| PubMed ID: 23973442	2014
Growth inhibition by pennogenyl saponins from Rhizoma paridis on hepatoma xenografts in nude mice. Steroids\| PubMed ID: 24530287	2014
Deciphering molecular mechanism underlying hypolipidemic activity of echinocystic Acid. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 24669228	2014
Ligustilide ameliorates neuroinflammation and brain injury in focal cerebral ischemia/reperfusion rats: involvement of inhibition of TLR4/peroxiredoxin 6 signaling. Free radical biology & medicine\| PubMed ID: 24681253	2014
Therapeutic efficacy of a novel non-peptide αvβ3 integrin antagonist for pathological retinal angiogenesis in mice. Experimental eye research\| PubMed ID: 25446322	2014
Pennogenyl saponins induce cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells. Journal of ethnopharmacology\| PubMed ID: 25562722	2015
Aging-related renal injury and inflammation are associated with downregulation of Klotho and induction of RIG-I/NF-κB signaling pathway in senescence-accelerated mice. Aging clinical and experimental research\| PubMed ID: 25986237	2016
Pharmacological characterization of a novel gastrodin derivative as a potential anti-migraine agent. Fitoterapia\| PubMed ID: 26704993	2016
Research Progress on Natural Triterpenoid Saponins in the Chemoprevention and Chemotherapy of Cancer. The Enzymes\| PubMed ID: 27102701	2014
Differences in Proinflammatory Property of Six Subtypes of Peroxiredoxins and Anti-Inflammatory Effect of Ligustilide in Macrophages. PloS one\| PubMed ID: 27716839	2016
Peroxiredoxin 1-mediated activation of TLR4/NF-κB pathway contributes to neuroinflammatory injury in intracerebral hemorrhage. International immunopharmacology\| PubMed ID: 27821296	2016
Neuroprotective Effect of Ligustilide through Induction of α-Secretase Processing of Both APP and Klotho in a Mouse Model of Alzheimer's Disease. Frontiers in aging neuroscience\| PubMed ID: 29163135	2017
Neuroprotective effect of a novel gastrodin derivative against ischemic brain injury: involvement of peroxiredoxin and TLR4 signaling inhibition. Oncotarget\| PubMed ID: 29207618	2017
Klotho upregulation contributes to the neuroprotection of ligustilide against cerebral ischemic injury in mice. European journal of pharmacology\| PubMed ID: 29233659	2018
Protective Effect of Klotho against Ischemic Brain Injury Is Associated with Inhibition of RIG-I/NF-κB Signaling. Frontiers in pharmacology\| PubMed ID: 29403373	2017
Lentivirus-mediated klotho up-regulation improves aging-related memory deficits and oxidative stress in senescence-accelerated mouse prone-8 mice. Life sciences\| PubMed ID: 29544758	2018
The neuroprotective effects and probable mechanisms of Ligustilide and its degradative products on intracerebral hemorrhage in mice. International immunopharmacology\| PubMed ID: 30075428	2018
Lentiviral vector-mediated overexpression of Klotho in the brain improves Alzheimer's disease-like pathology and cognitive deficits in mice. Neurobiology of aging\| PubMed ID: 30851437	2019
Dihydrodiosgenin inhibits endothelial cell-derived factor VIII and platelet-mediated hepatocellular carcinoma metastasis. Cancer management and research\| PubMed ID: 31239763	2019
Chronic periodontitis induces microbiota-gut-brain axis disorders and cognitive impairment in mice. Experimental neurology\| PubMed ID: 31926167	2020
Probiotics modulate the microbiota-gut-brain axis and improve memory deficits in aged SAMP8 mice. Acta pharmaceutica Sinica. B\| PubMed ID: 32140393	2020
[Effects of Low Concentration Hydrogen Inhalation on Asthma and Sleep Function in Mice]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition\| PubMed ID: 32220191	2020
Multi-functional nanocomplex codelivery of Trp2 and R837 to activate melanoma-specific immunity. International journal of pharmaceutics\| PubMed ID: 32276088	2020
Neuroprotective Effect of Phthalide Derivative CD21 against Ischemic Brain Injury:Involvement of MSR1 Mediated DAMP peroxiredoxin1 Clearance and TLR4 Signaling Inhibition. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology\| PubMed ID: 32291602	2021
Phthalide derivative CD21 ameliorates ischemic brain injury in a mouse model of global cerebral ischemia: involvement of inhibition of NLRP3. International immunopharmacology\| PubMed ID: 32593156	2020
Phthalide derivative CD21 alleviates cerebral ischemia-induced neuroinflammation: Involvement of microglial M2 polarization via AMPK activation. European journal of pharmacology\| PubMed ID: 32926919	2020
Klotho overexpression improves amyloid-β clearance and cognition in the APP/PS1 mouse model of Alzheimer's disease. Aging cell\| PubMed ID: 32964663	2020
Age-related cognitive decline is associated with microbiota-gut-brain axis disorders and neuroinflammation in mice. Behavioural brain research\| PubMed ID: 33422597	2021
Isoliquiritigenin Suppresses EMT-Induced Metastasis in Triple-Negative Breast Cancer through miR-200c/C-JUN/[Formula: see text]-Catenin. The American journal of Chinese medicine\| PubMed ID: 33641651	2021
Gut Microbiota in Tumor Microenvironment: A Critical Regulator in Cancer Initiation and Development as Potential Targets for Chinese Medicine. The American journal of Chinese medicine\| PubMed ID: 33683187	2021
Nrf2 signalling pathway and autophagy impact on the preventive effect of green tea extract against alcohol-induced liver injury. The Journal of pharmacy and pharmacology\| PubMed ID: 33877365	2021
Phthalide derivative CD21 attenuates tissue plasminogen activator-induced hemorrhagic transformation in ischemic stroke by enhancing macrophage scavenger receptor 1-mediated DAMP (peroxiredo... Journal of neuroinflammation\| PubMed ID: 34162400	2021
The novel LSD1 inhibitor ZY0511 suppresses diffuse large B-cell lymphoma proliferation by inducing apoptosis and autophagy. Medical oncology (Northwood, London, England)\| PubMed ID: 34491469	2021
Far beyond anti-angiogenesis: Benefits for anti-basicFGF therapy in cancer. Biochimica et biophysica acta. Molecular cell research\| PubMed ID: 35259425	2022
Maackiain Modulates miR-374a/GADD45A Axis to Inhibit Triple-Negative Breast Cancer Initiation and Progression. Frontiers in pharmacology\| PubMed ID: 35308218	2022
Regulation of temozolomide resistance via lncRNAs: Clinical and biological properties of lncRNAs in gliomas (Review). International journal of oncology\| PubMed ID: 35796022	2022
MicroRNAs, Key Regulators in Glioma Progression as Potential Therapeutic Targets for Chinese Medicine. The American journal of Chinese medicine\| PubMed ID: 36121713	2022
combined with inhibit glioma growth in mice through modulating PI3K/AKT pathway and gut microbiota. Frontiers in microbiology\| PubMed ID: 36147842	2022
Neuroprotective effect of alpha-kinase 1 knockdown against cerebral ischemia through inhibition of the NF-κB pathway and neuroinflammation. International immunopharmacology\| PubMed ID: 36274483	2022
Microglia autophagy in ischemic stroke: A double-edged sword. Frontiers in immunology\| PubMed ID: 36466850	2022
Phthalide derivative CD21 regulates the platelet- neutrophil extracellular trap-thrombin axis and protects against ischemic brain injury in rodents. International immunopharmacology\| PubMed ID: 36527877	2023
Probiotics Improve Cognitive Impairment by Decreasing Bacteria-Related Pattern Recognition Receptor-Mediated Inflammation in the Gut-Brain Axis of Mice. Journal of integrative neuroscience\| PubMed ID: 37519163	2023
NKG2D knockdown improves hypoxic-ischemic brain damage by inhibiting neuroinflammation in neonatal mice. Scientific reports\| PubMed ID: 38282118	2024
A novel phthalein component ameliorates neuroinflammation and cognitive dysfunction by suppressing the CXCL12/CXCR4 axis in rats with vascular dementia. Journal of ethnopharmacology\| PubMed ID: 38548120	2024
Multi-omics-based investigation of inhibitory effect on glioma: regulation of tumor and gut microbiota, and MEK/ERK cascade. Frontiers in microbiology\| PubMed ID: 38699473	2024
A G-quadruplex-binding platinum complex induces cancer mitochondrial dysfunction through dual-targeting mitochondrial and nuclear G4 enriched genome. Journal of biomedical science\| PubMed ID: 38741159	2024
Isocucurbitacin B inhibits glioma growth through PI3K/AKT pathways and increases glioma sensitivity to TMZ by inhibiting hsa-mir-1286a. Cancer drug resistance (Alhambra, Calif.)\| PubMed ID: 38835342	2024
A simple and economical method for unbiasedly quantifying the alveolar size of entire mouse lung tissue utilizing Hematoxylin and Eosin Staining. Acta histochemica\| PubMed ID: 38850586	2024
Design and Discovery of New Collagen V-Derived FGF2-Blocking Natural Peptides Inhibiting Lung Squamous Cell Carcinoma and . Journal of medicinal chemistry\| PubMed ID: 39045829	2024
QBT improved cognitive dysfunction in rats with vascular dementia by regulating the Nrf2/xCT/GPX4 and NLRP3/Caspase-1/GSDMD pathways to inhibit ferroptosis and pyroptosis of neurons. International immunopharmacology\| PubMed ID: 39265351	2024
Cell components of tumor microenvironment in lung adenocarcinoma: Promising targets for small-molecule compounds. Chinese medical journal\| PubMed ID: 39512221	2024
Correction: A G-quadruplex-binding platinum complex induces cancer mitochondrial dysfunction through dual-targeting mitochondrial and nuclear G4 enriched genome. Journal of biomedical science\| PubMed ID: 39681852	2024