Abdel G. Elkahloun

Cancer Genetics and Comparative Genomics Branch, National Institutes of Health

Affiliated withNational Institutes of Health

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2025

Other Publications

Article	Year
Macrophage migration inhibitory factor in drug-induced liver injury: a role in susceptibility and stress responsiveness. Biochemical and biophysical research communications\| PubMed ID: 12051698	2002
In situ gene expression analysis of cancer using laser capture microdissection, microarrays and real time quantitative PCR. Cancer biology & therapy\| PubMed ID: 12432245	2002
RNAi microarray analysis in cultured mammalian cells. Genome research\| PubMed ID: 14525932	2003
Different expression of catecholamine transporters in phaeochromocytomas from patients with von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2. European journal of endocrinology / European Federation of Endocrine Societies\| PubMed ID: 16189177	2005
Transcriptional regulation of phenylethanolamine N-methyltransferase in pheochromocytomas from patients with von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2. Annals of the New York Academy of Sciences\| PubMed ID: 17102092	2006
Gene expression profiling of rat pheochromocytoma. Annals of the New York Academy of Sciences\| PubMed ID: 17102098	2006
Gene expression profiling of benign and malignant pheochromocytoma. Annals of the New York Academy of Sciences\| PubMed ID: 17102123	2006
Neuropeptide Y expression in phaeochromocytomas: relative absence in tumours from patients with von Hippel-Lindau syndrome. The Journal of endocrinology\| PubMed ID: 17470513	2007
An early requirement for maternal FoxH1 during zebrafish gastrulation. Developmental biology\| PubMed ID: 17719025	2007
Transcriptional profiling of endogenous germ layer precursor cells identifies dusp4 as an essential gene in zebrafish endoderm specification. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18719100	2008
Characterization of an animal model of aggressive metastatic pheochromocytoma linked to a specific gene signature. Clinical & experimental metastasis\| PubMed ID: 19169894	2009
Overexpression of interleukin-13 receptor-alpha2 in neuroendocrine malignant pheochromocytoma: a novel target for receptor directed anti-cancer therapy. The Journal of clinical endocrinology and metabolism\| PubMed ID: 19491224	2009
Coat variation in the domestic dog is governed by variants in three genes. Science (New York, N.Y.)\| PubMed ID: 19713490	2009
A simple genetic architecture underlies morphological variation in dogs. PLoS biology\| PubMed ID: 20711490	2010
Isolation and characterization of a metastatic hybrid cell line generated by ER negative and ER positive breast cancer cells in mouse bone marrow. PloS one\| PubMed ID: 21673810	2011
Intranasal delivery of E-selectin reduces atherosclerosis in ApoE-/- mice. PloS one\| PubMed ID: 21701687	2011
Mutational inactivation of STAG2 causes aneuploidy in human cancer. Science (New York, N.Y.)\| PubMed ID: 21852505	2011
Loss of cytoplasmic CDK1 predicts poor survival in human lung cancer and confers chemotherapeutic resistance. PloS one\| PubMed ID: 21887332	2011
Functional and epigenetic studies reveal multistep differentiation and plasticity of in vitro-generated and in vivo-derived follicular T helper cells. Immunity\| PubMed ID: 22018472	2011
Temporal dynamics and genetic control of transcription in the human prefrontal cortex. Nature\| PubMed ID: 22031444	2011
Attenuation of TGF-β signaling suppresses premature senescence in a p21-dependent manner and promotes oncogenic Ras-mediated metastatic transformation in human mammary epithelial cells. Molecular biology of the cell\| PubMed ID: 22357622	2012
Post-insult valproic acid-regulated microRNAs: potential targets for cerebral ischemia. American journal of translational research\| PubMed ID: 22937209	2012
A novel function of RNAs arising from the long terminal repeat of human endogenous retrovirus 9 in cell cycle arrest. Journal of virology\| PubMed ID: 23097441	2013
PBX3 is an important cofactor of HOXA9 in leukemogenesis. Blood\| PubMed ID: 23264595	2013
Genotype and tumor locus determine expression profile of pseudohypoxic pheochromocytomas and paragangliomas. Neoplasia (New York, N.Y.)\| PubMed ID: 23555188	2013
Mood stabilizer-regulated miRNAs in neuropsychiatric and neurodegenerative diseases: identifying associations and functions. American journal of translational research\| PubMed ID: 23724168	2013
miR-9 is an essential oncogenic microRNA specifically overexpressed in mixed lineage leukemia-rearranged leukemia. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23798388	2013
TET1 plays an essential oncogenic role in MLL-rearranged leukemia. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23818607	2013
Targeting proximal tubule mitochondrial dysfunction attenuates the renal disease of methylmalonic acidemia. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23898205	2013
Derivation of neural stem cells from human adult peripheral CD34+ cells for an autologous model of neuroinflammation. PloS one\| PubMed ID: 24303066	2013
Identification of candidate genes involved in coronary artery calcification by transcriptome sequencing of cell lines. BMC genomics\| PubMed ID: 24628908	2014
Anti-cancer potential of MAPK pathway inhibition in paragangliomas-effect of different statins on mouse pheochromocytoma cells. PloS one\| PubMed ID: 24846270	2014
CD47-dependent immunomodulatory and angiogenic activities of extracellular vesicles produced by T cells. Matrix biology : journal of the International Society for Matrix Biology\| PubMed ID: 24887393	2014
Targeted correction of RUNX1 mutation in FPD patient-specific induced pluripotent stem cells rescues megakaryopoietic defects. Blood\| PubMed ID: 25114263	2014
Germ-line PHD1 and PHD2 mutations detected in patients with pheochromocytoma/paraganglioma-polycythemia. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 25263965	2015
Cell transcriptional state alters genomic patterns of DNA double-strand break repair in human astrocytes. Nature communications\| PubMed ID: 25517576	2014
Vector design influences hepatic genotoxicity after adeno-associated virus gene therapy. The Journal of clinical investigation\| PubMed ID: 25607839	2015
Rescue of CD8+ T cell vaccine memory following sublethal γ irradiation. Vaccine\| PubMed ID: 26122582	2015
Overexpression and knockout of miR-126 both promote leukemogenesis. Blood\| PubMed ID: 26361793	2015
An integrative genome-wide transcriptome reveals that candesartan is neuroprotective and a candidate therapeutic for Alzheimer's disease. Alzheimer's research & therapy\| PubMed ID: 26822027	2016
A function-blocking CD47 antibody suppresses stem cell and EGF signaling in triple-negative breast cancer. Oncotarget\| PubMed ID: 26840086	2016
A heterogeneous population of nuclear-encoded mitochondrial mRNAs is present in the axons of primary sympathetic neurons. Mitochondrion\| PubMed ID: 27318271	2016
Dopamine is Required for Activity-Dependent Amplification of Arc mRNA in Developing Postnatal Frontal Cortex. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 27365296	2016
Differentiation of human and murine induced pluripotent stem cells to microglia-like cells. Nature neuroscience\| PubMed ID: 28253233	2017
Chronic social defeat reduces myelination in the mouse medial prefrontal cortex. Scientific reports\| PubMed ID: 28418035	2017
A function-blocking CD47 antibody modulates extracellular vesicle-mediated intercellular signaling between breast carcinoma cells and endothelial cells. Journal of cell communication and signaling\| PubMed ID: 29188480	2018
CD63, MHC class 1, and CD47 identify subsets of extracellular vesicles containing distinct populations of noncoding RNAs. Scientific reports\| PubMed ID: 29416092	2018
Decoding microglia responses to psychosocial stress reveals blood-brain barrier breakdown that may drive stress susceptibility. Scientific reports\| PubMed ID: 30050134	2018
Telmisartan Protects a Microglia Cell Line from LPS Injury Beyond AT1 Receptor Blockade or PPARγ Activation. Molecular neurobiology\| PubMed ID: 30105672	2019
RASA2 and NF1; two-negative regulators of Ras with complementary functions in melanoma. Oncogene\| PubMed ID: 30478445	2019
FGF21 underlies a hormetic response to metabolic stress in methylmalonic acidemia. JCI insight\| PubMed ID: 30518688	2018
Recurrent microdeletions at chromosome 2p11.2 are associated with thymic hypoplasia and features resembling DiGeorge syndrome. The Journal of allergy and clinical immunology\| PubMed ID: 31600545	2020
Identification of Schlafen-11 as a Target of CD47 Signaling That Regulates Sensitivity to Ionizing Radiation and Topoisomerase Inhibitors. Frontiers in oncology\| PubMed ID: 31632920	2019
Candesartan Neuroprotection in Rat Primary Neurons Negatively Correlates with Aging and Senescence: a Transcriptomic Analysis. Molecular neurobiology\| PubMed ID: 31811565	2020
Analysis of cerebrovascular dysfunction caused by chronic social defeat in mice. Brain, behavior, and immunity\| PubMed ID: 32413560	2020
Candesartan could ameliorate the COVID-19 cytokine storm. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 32942152	2020
Cell-penetrating, antioxidant SELENOT mimetic protects dopaminergic neurons and ameliorates motor dysfunction in Parkinson's disease animal models. Redox biology\| PubMed ID: 33486153	2021
CD63 and MHC Class I Subsets of Extracellular Vesicles Produced by Wild-Type and CD47-Deficient Jurkat T Cells Have Divergent Functional Effects on Endothelial Cell Gene Expression. Biomedicines\| PubMed ID: 34829933	2021
CD47 interactions with exportin-1 limit the targeting of mG-modified RNAs to extracellular vesicles. Journal of cell communication and signaling\| PubMed ID: 34841476	2022
A regulatory network of Sox and Six transcription factors initiate a cell fate transformation during hearing regeneration in adult zebrafish. Cell genomics\| PubMed ID: 36212030	2022
Chronic social defeat alters brain vascular-associated cell gene expression patterns leading to vascular dysfunction and immune system activation. Journal of neuroinflammation\| PubMed ID: 37380974	2023