modified-laparoscopic-inguinal-lymphadenectomy-using-an-abdominal

Modified Laparoscopic Inguinal Lymphadenectomy Using an Abdominal Subcutaneous Approach

Inguinal lymph node metastases significantly impact the prognosis of patients with penile cancer. Therefore, timely inguinal lymph node dissection is ...

Guangdong Hospital of Traditional Chinese Medicine

Prostate cancer (PCa) is a malignant tumor in males, with a majority of the cases advancing to metastatic castration resistance. Metastasis is the leading cause of mortality in PCa. The traditional early detection and prediction approaches cannot differentiate between the different stages of PCa. Therefore, new biomarkers are necessary for early detection and clear differentiation of PCa stages to provide precise therapeutic intervention.

Identification of the Key Genes Involved in the Tumorigenesis and Prognosis of Prostate Cancer.

Current diagnosis tools for prostate cancer (PCa) such as serum PSA detection and prostate biopsy cannot distinguish dormant tumors from invasive malignancies, either be used as prognosis marker for castration resistant prostate cancer (CRPC), the lethal stage of PCa patients. Exosomes have been widely investigated as promising biomarkers for various diseases. We aim to characterize the proteomic and metabolomic profile of exosomes and to evaluate their potential value for the diagnosis of PCa, especially CRPC. We also investigate the functions of some specific exosome biomarkers in the progression of CRPC.

Article	Year
Identification of the Key Genes Involved in the Tumorigenesis and Prognosis of Prostate Cancer. Computational and mathematical methods in medicine\| PubMed ID: 36245843	2022
Alterations of plasma exosomal proteins and motabolies are associated with the progression of castration-resistant prostate cancer. Journal of translational medicine\| PubMed ID: 36681849	2023

Wenxuan Wang

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