Leslie E. Huye

Center for Cell and Gene Therapy, Baylor College of Medicine

Affiliated withBaylor College of Medicine

Research Area

Immunology and Infection

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 16	2012

Other Publications

Article	Year
Mutational analysis of all conserved basic amino acids in RAG-1 reveals catalytic, step arrest, and joining-deficient mutants in the V(D)J recombinase. Molecular and cellular biology\| PubMed ID: 11971977	2002
The V(D)J recombinase efficiently cleaves and transposes signal joints. Molecular cell\| PubMed ID: 11983177	2002
Contribution of Vh gene replacement to the primary B cell repertoire. Immunity\| PubMed ID: 12871636	2003
Interferon regulatory factor 7 regulates expression of Epstein-Barr virus latent membrane protein 1: a regulatory circuit. Journal of virology\| PubMed ID: 12915551	2003
Regulation of the transcriptional activity of the IRF7 promoter by a pathway independent of interferon signaling. The Journal of biological chemistry\| PubMed ID: 15664995	2005
Interferon regulatory factor 7 is negatively regulated by the Epstein-Barr virus immediate-early gene, BZLF-1. Journal of virology\| PubMed ID: 16014964	2005
Interferon regulatory factor 5 represses expression of the Epstein-Barr virus oncoprotein LMP1: braking of the IRF7/LMP1 regulatory circuit. Journal of virology\| PubMed ID: 16140744	2005
Interferon regulatory factor 7 is activated by a viral oncoprotein through RIP-dependent ubiquitination. Molecular and cellular biology\| PubMed ID: 17296724	2007
Optimization of the PiggyBac transposon system for the sustained genetic modification of human T lymphocytes. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 19752751	2009
Generation of Epstein-Barr virus-specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506). Blood\| PubMed ID: 19759356	2009
Designing T cells for cancer immunotherapy. Discovery medicine\| PubMed ID: 20423673	2010
T cells expressing constitutively active Akt resist multiple tumor-associated inhibitory mechanisms. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 20842106	2010
PiggyBac-mediated cancer immunotherapy using EBV-specific cytotoxic T-cells expressing HER2-specific chimeric antigen receptor. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 21772253	2011
Combining mTor inhibitors with rapamycin-resistant T cells: a two-pronged approach to tumor elimination. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 21878902	2011
Hyperactive piggyBac gene transfer in human cells and in vivo. Human gene therapy\| PubMed ID: 21992617	2012
Rapidly generated multivirus-specific cytotoxic T lymphocytes for the prophylaxis and treatment of viral infections. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 22801446	2012