Luke Wiley

Institute for Vision Research, University of Iowa

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2025

Other Publications

Article	Year
Mechanical properties of murine and porcine ocular tissues in compression. Experimental eye research\| PubMed ID: 24613781	2014
Duplication of TBK1 Stimulates Autophagy in iPSC-derived Retinal Cells from a Patient with Normal Tension Glaucoma. Journal of stem cell research & therapy\| PubMed ID: 24883232	2014
Gene therapy using stem cells. Cold Spring Harbor perspectives in medicine\| PubMed ID: 25395375	2014
Patient-specific induced pluripotent stem cells (iPSCs) for the study and treatment of retinal degenerative diseases. Progress in retinal and eye research\| PubMed ID: 25448922	2015
Stem cells as tools for studying the genetics of inherited retinal degenerations. Cold Spring Harbor perspectives in medicine\| PubMed ID: 25502747	2014
Prevascularized silicon membranes for the enhancement of transport to implanted medical devices. Journal of biomedical materials research. Part B, Applied biomaterials\| PubMed ID: 26316050	2016
Hypomorphic mutations in TRNT1 cause retinitis pigmentosa with erythrocytic microcytosis. Human molecular genetics\| PubMed ID: 26494905	2016
North Carolina Macular Dystrophy Is Caused by Dysregulation of the Retinal Transcription Factor PRDM13. Ophthalmology\| PubMed ID: 26507665	2016
Molecular response of chorioretinal endothelial cells to complement injury: implications for macular degeneration. The Journal of pathology\| PubMed ID: 26564985	2016
Concise Review: Patient-Specific Stem Cells to Interrogate Inherited Eye Disease. Stem cells translational medicine\| PubMed ID: 26683869	2016
Differentiation of Induced Pluripotent Stem Cells to Neural Retinal Precursor Cells on Porous Poly-Lactic-co-Glycolic Acid Scaffolds. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics\| PubMed ID: 26692377	2016
Generating iPSC-Derived Choroidal Endothelial Cells to Study Age-Related Macular Degeneration. Investigative ophthalmology & visual science\| PubMed ID: 26720480	2015
Neuronal Differentiation of Induced Pluripotent Stem Cells on Surfactant Templated Chitosan Hydrogels. Biomacromolecules\| PubMed ID: 27008004	2016
A Method for Sectioning and Immunohistochemical Analysis of Stem Cell-Derived 3-D Organoids. Current protocols in stem cell biology\| PubMed ID: 27171793	2016
Using Patient-Specific Induced Pluripotent Stem Cells and Wild-Type Mice to Develop a Gene Augmentation-Based Strategy to Treat CLN3-Associated Retinal Degeneration. Human gene therapy\| PubMed ID: 27400765	2016
Impaired autophagy in macrophages promotes inflammatory eye disease. Autophagy\| PubMed ID: 27463423	2016
cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness. Scientific reports\| PubMed ID: 27471043	2016
Two-photon polymerization for production of human iPSC-derived retinal cell grafts. Acta biomaterialia\| PubMed ID: 28351682	2017
Patient-specific induced pluripotent stem cells to evaluate the pathophysiology of TRNT1-associated Retinitis pigmentosa. Stem cell research\| PubMed ID: 28390992	2017
Using CRISPR-Cas9 to Generate Gene-Corrected Autologous iPSCs for the Treatment of Inherited Retinal Degeneration. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 28619647	2017
Generation of Xeno-Free, cGMP-Compliant Patient-Specific iPSCs from Skin Biopsy. Current protocols in stem cell biology\| PubMed ID: 28806854	2017
Assessment of Adeno-Associated Virus Serotype Tropism in Human Retinal Explants. Human gene therapy\| PubMed ID: 29160116	2018
CRISPR-Cas9 genome engineering: Treating inherited retinal degeneration. Progress in retinal and eye research\| PubMed ID: 29578069	2018
Feeder-free differentiation of cells exhibiting characteristics of corneal endothelium from human induced pluripotent stem cells. Biology open\| PubMed ID: 29685994	2018
WNT7A/B promote choroidal neovascularization. Experimental eye research\| PubMed ID: 29864439	2018
Effect of Molecular Weight and Functionality on Acrylated Poly(caprolactone) for Stereolithography and Biomedical Applications. Biomacromolecules\| PubMed ID: 30044915	2018
Correction of NR2E3 Associated Enhanced S-cone Syndrome Patient-specific iPSCs using CRISPR-Cas9. Genes\| PubMed ID: 30959774	2019
Optimizing Donor Cellular Dissociation and Subretinal Injection Parameters for Stem Cell-Based Treatments. Stem cells translational medicine\| PubMed ID: 31004408	2019
CRISPR-Cas9-Mediated Correction of the 1.02 kb Common Deletion in in Induced Pluripotent Stem Cells from Patients with Batten Disease. The CRISPR journal\| PubMed ID: 31021193	2018
Two-photon polymerized poly(caprolactone) retinal cell delivery scaffolds and their systemic and retinal biocompatibility. Acta biomaterialia\| PubMed ID: 31055121	2019
Development of High-Resolution Three-Dimensional-Printed Extracellular Matrix Scaffolds and Their Compatibility with Pluripotent Stem Cells and Early Retinal Cells. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics\| PubMed ID: 31414943	2020
Helper-Dependent Adenovirus Transduces the Human and Rat Retina but Elicits an Inflammatory Reaction When Delivered Subretinally in Rats. Human gene therapy\| PubMed ID: 31456426	2019
AUTOIMMUNE RETINOPATHY MIMICKING HERITABLE RETINAL DEGENERATION IN A PATIENT WITH COMMON VARIABLE IMMUNE DEFICIENCY. Retinal cases & brief reports\| PubMed ID: 31764884	2022
Retinal Tropism and Transduction of Adeno-Associated Virus Varies by Serotype and Route of Delivery (Intravitreal, Subretinal, or Suprachoroidal) in Rats. Human gene therapy\| PubMed ID: 32948113	2020
The effect of retinal scaffold modulus on performance during surgical handling. Experimental eye research\| PubMed ID: 33838142	2021
Development and biological characterization of a clinical gene transfer vector for the treatment of MAK-associated retinitis pigmentosa. Gene therapy\| PubMed ID: 34518651	2022
Chimeric Helper-Dependent Adenoviruses Transduce Retinal Ganglion Cells and Müller Cells in Human Retinal Explants. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics\| PubMed ID: 34597181	2021
Choroidal endothelial and macrophage gene expression in atrophic and neovascular macular degeneration. Human molecular genetics\| PubMed ID: 35181781	2022
Biocompatibility of Human Induced Pluripotent Stem Cell-Derived Retinal Progenitor Cell Grafts in Immunocompromised Rats. Cell transplantation\| PubMed ID: 35758274	2022
Characterization of a novel Pde6b-deficient rat model of retinal degeneration and treatment with adeno-associated virus (AAV) gene therapy. Gene therapy\| PubMed ID: 36175490	2023
The Degree of Adeno-Associated Virus-Induced Retinal Inflammation Varies Based on Serotype and Route of Delivery: Intravitreal, Subretinal, or Suprachoroidal. Human gene therapy\| PubMed ID: 36793189	2023
CRISPRi-Mediated Treatment of Dominant Rhodopsin-Associated Retinitis Pigmentosa. The CRISPR journal\| PubMed ID: 38108516	2023