Constance Cepko

Howard Hughes Medical Institute, Harvard Medical School

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 10	2012

Other Publications

Article	Year
Profile of the genes expressed in the human peripheral retina, macula, and retinal pigment epithelium determined through serial analysis of gene expression (SAGE). Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11756676	2002
Sox-9 and cDachsund-2 expression in the developing chick telencephalon. Mechanisms of development\| PubMed ID: 11850191	2002
Mutations in the inosine monophosphate dehydrogenase 1 gene (IMPDH1) cause the RP10 form of autosomal dominant retinitis pigmentosa. Human molecular genetics\| PubMed ID: 11875050	2002
The mouse Crx 5'-upstream transgene sequence directs cell-specific and developmentally regulated expression in retinal photoreceptor cells. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 11880494	2002
Ena/VASP proteins regulate cortical neuronal positioning. Current biology : CB\| PubMed ID: 11937025	2002
The chicken RaxL gene plays a role in the initiation of photoreceptor differentiation. Development (Cambridge, England)\| PubMed ID: 12403708	2002
The dorsal-ventral axis of the neural retina is divided into multiple domains of restricted gene expression which exhibit features of lineage compartments. Developmental biology\| PubMed ID: 12413898	2002
Stem cells that know their place. Nature neuroscience\| PubMed ID: 12447376	2002
Irx4-mediated regulation of Slit1 expression contributes to the definition of early axonal paths inside the retina. Development (Cambridge, England)\| PubMed ID: 12571096	2003
MicroSAGE is highly representative and reproducible but reveals major differences in gene expression among samples obtained from similar tissues. Genome biology\| PubMed ID: 12620102	2003
Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina. Nature genetics\| PubMed ID: 12692551	2003
Electroporation and RNA interference in the rodent retina in vivo and in vitro. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14603031	2004
Thyroid hormone and retinal development: an emerging field. Thyroid : official journal of the American Thyroid Association\| PubMed ID: 14651785	2003
Inner retinal abnormalities in a mouse model of Leber's congenital amaurosis. The Journal of comparative neurology\| PubMed ID: 14730587	2004
Rb regulates proliferation and rod photoreceptor development in the mouse retina. Nature genetics\| PubMed ID: 14991054	2004
A role for ligand-gated ion channels in rod photoreceptor development. Neuron\| PubMed ID: 15046720	2004
Genetic analysis of the homeodomain transcription factor Chx10 in the retina using a novel multifunctional BAC transgenic mouse reporter. Developmental biology\| PubMed ID: 15223342	2004
Genomic analysis of mouse retinal development. PLoS biology\| PubMed ID: 15226823	2004
Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10. Development (Cambridge, England)\| PubMed ID: 15459106	2004
Methionine adenosyltransferase:adrenergic-cAMP mechanism regulates a daily rhythm in pineal expression. The Journal of biological chemistry\| PubMed ID: 15504733	2005
Synaptogenesis and outer segment formation are perturbed in the neural retina of Crx mutant mice. BMC neuroscience\| PubMed ID: 15676071	2005
The rod photoreceptor pattern is set at the optic vesicle stage and requires spatially restricted cVax expression. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 15772342	2005
A POU factor binding site upstream of the Chx10 homeobox gene is required for Chx10 expression in subsets of retinal progenitor cells and bipolar cells. Developmental biology\| PubMed ID: 15893976	2005
A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome. PLoS genetics\| PubMed ID: 16110338	2005
Retinoic acid regulates the expression of dorsoventral topographic guidance molecules in the chick retina. Development (Cambridge, England)\| PubMed ID: 16251210	2005
Effect of gene expression on cone survival in retinitis pigmentosa. Retina (Philadelphia, Pa.)\| PubMed ID: 16374320	2005
RCAS-RNAi: a loss-of-function method for the developing chick retina. BMC developmental biology\| PubMed ID: 16426460	2006
Notch 1 inhibits photoreceptor production in the developing mammalian retina. Development (Cambridge, England)\| PubMed ID: 16452096	2006
dILA neurons in the dorsal spinal cord are the product of terminal and non-terminal asymmetric progenitor cell divisions, and require Mash1 for their development. Development (Cambridge, England)\| PubMed ID: 16690754	2006
Wnt2b/beta-catenin-mediated canonical Wnt signaling determines the peripheral fates of the chick eye. Development (Cambridge, England)\| PubMed ID: 16854977	2006
Notch activity permits retinal cells to progress through multiple progenitor states and acquire a stem cell property. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17148603	2006
Controlled expression of transgenes introduced by in vivo electroporation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17209010	2007
Cellular responses to photoreceptor death in the rd1 mouse model of retinal degeneration. Investigative ophthalmology & visual science\| PubMed ID: 17251487	2007
Automatic correspondence of tags and genes (ACTG): a tool for the analysis of SAGE, MPSS and SBS data. Bioinformatics (Oxford, England)\| PubMed ID: 17277333	2007
Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. The Journal of comparative neurology\| PubMed ID: 17444492	2007
Local retinal circuits of melanopsin-containing ganglion cells identified by transsynaptic viral tracing. Current biology : CB\| PubMed ID: 17524644	2007
Requirement of histone deacetylase activity for the expression of critical photoreceptor genes. BMC developmental biology\| PubMed ID: 17603891	2007
A typology of photoreceptor gene expression patterns in the mouse. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17620597	2007
The cis-regulatory logic of the mammalian photoreceptor transcriptional network. PloS one\| PubMed ID: 17653270	2007
Temporal order of bipolar cell genesis in the neural retina. Neural development\| PubMed ID: 18215319	2008
Identification of molecular markers of bipolar cells in the murine retina. The Journal of comparative neurology\| PubMed ID: 18260140	2008
Individual retinal progenitor cells display extensive heterogeneity of gene expression. PloS one\| PubMed ID: 18270576	2008
Ultrasound-guided in utero injections allow studies of the development and function of the eye. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 18351670	2008
Analysis of gene function in the retina. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 18370205	2008
Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration. Nature neuroscience\| PubMed ID: 18432197	2008
Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18463241	2008
The transcriptome of retinal MÃ¼ller glial cells. The Journal of comparative neurology\| PubMed ID: 18465787	2008
A core paired-type and POU homeodomain-containing transcription factor program drives retinal bipolar cell gene expression. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 18667607	2008
Thyroid hormone components are expressed in three sequential waves during development of the chick retina. BMC developmental biology\| PubMed ID: 18854032	2008
Temporal requirement of the alternative-splicing factor Sfrs1 for the survival of retinal neurons. Development (Cambridge, England)\| PubMed ID: 18987029	2008
Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa. Nature neuroscience\| PubMed ID: 19060896	2009
HDAC4 regulates neuronal survival in normal and diseased retinas. Science (New York, N.Y.)\| PubMed ID: 19131628	2009
Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 19449303	2009
Developmental sources of conservation and variation in the evolution of the primate eye. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19451636	2009
Development and neurogenic potential of MÃ¼ller glial cells in the vertebrate retina. Progress in retinal and eye research\| PubMed ID: 19465144	2009
Development and diversification of retinal amacrine interneurons at single cell resolution. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19470466	2009
Robust marking of photoreceptor cells and pinealocytes with several reporters under control of the Crx gene. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 19882727	2009
Alternative splicing produces high levels of noncoding isoforms of bHLH transcription factors during development. Genes & development\| PubMed ID: 20080942	2010
Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen. Nature\| PubMed ID: 20090754	2010
A common progenitor for retinal astrocytes and oligodendrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 20371817	2010
Potent delivery of functional proteins into Mammalian cells in vitro and in vivo using a supercharged protein. ACS chemical biology\| PubMed ID: 20545362	2010
Neuroscience. Seeing the light of day. Science (New York, N.Y.)\| PubMed ID: 20651144	2010
Analysis of thyroid response element activity during retinal development. PloS one\| PubMed ID: 21060789	2010
An isoform-specific SnoN1-FOXO1 repressor complex controls neuronal morphogenesis and positioning in the mammalian brain. Neuron\| PubMed ID: 21382553	2011
Conditional expression of the TVA receptor allows clonal analysis of descendents from Cre-expressing progenitor cells. Developmental biology\| PubMed ID: 21397594	2011
NeuroD factors regulate cell fate and neurite stratification in the developing retina. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 21593321	2011
A class of human proteins that deliver functional proteins into mammalian cells in vitro and in vivo. Chemistry & biology\| PubMed ID: 21802004	2011
Anterograde or retrograde transsynaptic labeling of CNS neurons with vesicular stomatitis virus vectors. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21825165	2011
Restraint of angiogenesis by zinc finger transcription factor CTCF-dependent chromatin insulation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 21896759	2011
Identification of a retina-specific Otx2 enhancer element active in immature developing photoreceptors. Developmental biology\| PubMed ID: 21963459	2011
Loss of daylight vision in retinal degeneration: are oxidative stress and metabolic dysregulation to blame? The Journal of biological chemistry\| PubMed ID: 22074929	2012
Transcription factor Olig2 defines subpopulations of retinal progenitor cells biased toward specific cell fates. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22543161	2012
Emerging gene therapies for retinal degenerations. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 22573664	2012
Gene expression changes within MÃ¼ller glial cells in retinitis pigmentosa. Molecular vision\| PubMed ID: 22665967	2012