Lei Song

Lei Song

Department of Respiratory Medicine, The First Hospital of Jilin University

Affiliated withThe First Hospital of Jilin University

Research Area

Biography

Yuguo Song is a clinical doctor and professor specialized in Occupational Medicine & Clinical Toxicology. He works as a chief-physician and an associate director at the Department of Occupational Medicine & Clinical Toxicology, Beijing Chaoyang Hospital, Capital Medical University (Beijing, China). He received his B.S degree in clinical medicine from the University of Tsingdao Medical College, Shandong Province in 1990, and then he got his MD and Ph.D degree in Capital Medical University. He is the recipient of several research achievement awards including Wu Zhizhong Prize in occupational medicine (China) and International Travel Award from the American Academy of Clinical Toxicology. He ever worked as a visiting scholar in 2010 at West Virginia University, USA. His research focus is clinical toxicology, nanotoxicology, metal toxicology and occupational lung diseases.

1. Cao W, Zhou Y, Niu Y, Zhu X, Song Y, Guo R. Quantitative analysis of hepatic toxicity in rats induced by inhalable silica nanoparticles using acoustic radiation force imaging. J Ultrasound Med. 2017,36(9) :1829-1839.

2. Zhu X, Cao W, Chang B, Zhang L, Qiao P, Li X, Si L, Niu Y, Song Y . Polyacrylate/nanosilica causes pleural and pericardial effusion, and pulmonary fibrosis and granuloma in rats similar to those observed in exposed workers. Int J Nanomedicine 2016;11:1593-605.

3.Niu YM, Zhu XL, Chang B, Tong ZH, Cao W, Qiao PH, Zhang LY, Zhao J, Song YG. Nanosilica and polyacrylate/nanosilica: a comparative study of acute toxicity. Biomed Res Int. 2016. 2016: 9353275.

4. Song Y, Li X, Wang L, Rojanasakul Y, Castranova V, Li H, Ma J. Nanomaterials in humans: identification, characteristics, and potential damage. Toxicol Pathol. 2011;39(5):841-849.

5. Song Y, Tang S. Nanoexposure, unusual diseases, and new health and safety concerns. TheScientificWorldJOURNAL. 2011, 11: 1821–1828.

6. Song Y, Du X, Hao F, Gu X, Zhang Z, Zhang S, Li C, Li H, Ma J. Immunosuppressive therapy of cyclosporin A for severe benzene-induced haematopoietic disorders and a 6-month follow-up. Chem Biol Interact. 2010;186(1):96-102.

7. Song Y, Li X, Du X. Exposure to nanoparticles is related to pleural effusion, pulmonary fibrosis and granuloma. Eur Respir J. 2009; 34(3):559-567.

JoVE Journal Publications

ArticleTotal : 4
Year
Rapid and Specific Detection of <em>Acinetobacter baumannii</em> Infections Using a Recombinase Polymerase Amplification/Cas12a-based System
Publication title
2025
Establishment and Comparison of Fluorescence-Based T6SS Activity Detection Methods in <em>Acinetobacter baumannii</em>
Publication title

Cited by 2

2025
2025
2026

Other Publications

Article
Year
rAAV/ABAD-DP-6His attenuates oxidative stress-induced injury of PC12 cells.

Neural regeneration research| PubMed ID: 25206842

2014
piR-55490 inhibits the growth of lung carcinoma by suppressing mTOR signaling.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine| PubMed ID: 26408181

2016
Upregulation of microRNA-31 targeting integrin α5 suppresses tumor cell invasion and metastasis by indirectly regulating PI3K/AKT pathway in human gastric cancer SGC7901 cells.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine| PubMed ID: 26729197

2016
2016
2016
2016
Relationships of MMP-9 and TIMP-1 proteins with chronic obstructive pulmonary disease risk: A systematic review and meta-analysis.

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences| PubMed ID: 27904558

2016
2017
2017
2017
WITHAFERIN A INDUCES APOPTOSIS IN RAT C6 GLIOMA CELLS THROUGH REGULATING NF-KB NUCLEAR TRANSLOCATION AND ACTIVATION OF CASPASE CASCADE.

African journal of traditional, complementary, and alternative medicines : AJTCAM| PubMed ID: 28573248

2017
Inhibition of MicroRNA-21-5p Promotes the Radiation Sensitivity of Non-Small Cell Lung Cancer Through HMSH2.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology| PubMed ID: 29024929

2017
2018
2018
Post-translational regulation of ubiquitin signaling.

The Journal of cell biology| PubMed ID: 31000580

2019
2020
2020
2020
2020
2020
2021
2021
2021
Calycosin Alleviates Injury in Airway Epithelial Cells Caused by PM 2.5 Exposure via Activation of AMPK Signalling.

Evidence-based complementary and alternative medicine : eCAM| PubMed ID: 34055025

2021
Novel Role of miR-18a-5p and Galanin in Rat Lung Ischemia Reperfusion-Mediated Response.

Oxidative medicine and cellular longevity| PubMed ID: 34497682

2021
2021
2021
inhibits host immunity by a protein phosphatase adapted from glycolysis.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 34930823

Exploitation of the Host Ubiquitin System: Means by .

Frontiers in microbiology| PubMed ID: 35003021

Maackiain protects against sepsis via activating AMPK/Nrf2/HO-1 pathway.

International immunopharmacology| PubMed ID: 35405595

PM2.5 Exposure and Asthma Development: The Key Role of Oxidative Stress.

Oxidative medicine and cellular longevity| PubMed ID: 35419163

Subversion of host cell signaling: The arsenal of Rickettsial species.

Frontiers in cellular and infection microbiology| PubMed ID: 36389139

2022
2023
2023
2022
2023
2023
The versatile defender: exploring the multifaceted role of p62 in intracellular bacterial infection.

Frontiers in cellular and infection microbiology| PubMed ID: 37216179

2023
2023
Ferroptosis in pulmonary fibrosis: an emerging therapeutic target.

Frontiers in physiology| PubMed ID: 37664432

2023
2023
The intricate dance: host autophagy and infection.

Frontiers in microbiology| PubMed ID: 37808314

2023
2024
2024
Unveiling the Intricacies of Autophagy in Asthma: Unraveling Novel Therapeutic Avenues.

Frontiers in bioscience (Landmark edition)| PubMed ID: 38287830

2024
2024
2024
2022
2024
2024
2024
2024
Insights into the role of legionella effectors on host metabolic perturbations.

Frontiers in cellular and infection microbiology| PubMed ID: 39324059

2024
2024
2024
2024
2025
2025
2025
Modulation of host ATP levels by secreted bacterial effectors.

Nature communications| PubMed ID: 40394005

2025
2025
2025
2025
2025
2025
2025
From commensalism to pathogenesis: the hidden role of the respiratory virome.

Frontiers in cellular and infection microbiology| PubMed ID: 41181319

2025
Bacteria block host cell death by protein cut-and-paste.

Cell host & microbe| PubMed ID: 41232517

2025