Timothy D. Folsom

Department of Pediatrics, University of Minnesota

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Chronic olanzapine treatment causes differential expression of genes in frontal cortex of rats as revealed by DNA microarray technique. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology\| PubMed ID: 16407901	2006
Viral regulation of aquaporin 4, connexin 43, microcephalin and nucleolin. Schizophrenia research\| PubMed ID: 17997079	2008
Expression of phosphodiesterase 4 is altered in the brains of subjects with autism. Neuroreport\| PubMed ID: 18090323	2007
Maternal infection leads to abnormal gene regulation and brain atrophy in mouse offspring: implications for genesis of neurodevelopmental disorders. Schizophrenia research\| PubMed ID: 18248790	2008
PDE4B polymorphisms and decreased PDE4B expression are associated with schizophrenia. Schizophrenia research\| PubMed ID: 18394866	2008
The role of cerebellar genes in pathology of autism and schizophrenia. Cerebellum (London, England)\| PubMed ID: 18418686	2008
Expression of astrocytic markers aquaporin 4 and connexin 43 is altered in brains of subjects with autism. Synapse (New York, N.Y.)\| PubMed ID: 18435417	2008
Chronic psychotropic drug treatment causes differential expression of connexin 43 and GFAP in frontal cortex of rats. Schizophrenia research\| PubMed ID: 18585900	2008
Dopamine and serotonin levels following prenatal viral infection in mouse--implications for psychiatric disorders such as schizophrenia and autism. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology\| PubMed ID: 18693086	2008
GABA(A) receptor downregulation in brains of subjects with autism. Journal of autism and developmental disorders\| PubMed ID: 18821008	2009
Expression of GABA(B) receptors is altered in brains of subjects with autism. Cerebellum (London, England)\| PubMed ID: 19002745	2009
Phosphodiesterase-4A expression is reduced in cerebella of patients with bipolar disorder. Psychiatric genetics\| PubMed ID: 19018233	2008
The neurodevelopmental hypothesis of schizophrenia, revisited. Schizophrenia bulletin\| PubMed ID: 19223657	2009
Chronic psychotropic drug treatment causes differential expression of Reelin signaling system in frontal cortex of rats. Schizophrenia research\| PubMed ID: 19359144	2009
Abnormal expression of myelination genes and alterations in white matter fractional anisotropy following prenatal viral influenza infection at E16 in mice. Schizophrenia research\| PubMed ID: 19487109	2009
Prenatal viral infection of mice at E16 causes changes in gene expression in hippocampi of the offspring. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology\| PubMed ID: 19501487	2009
The role of lithium in modulation of brain genes: relevance for aetiology and treatment of bipolar disorder. Biochemical Society transactions\| PubMed ID: 19754458	2009
mRNA and protein levels for GABAAalpha4, alpha5, beta1 and GABABR1 receptors are altered in brains from subjects with autism. Journal of autism and developmental disorders\| PubMed ID: 20066485	2010
Levels of phosphodiesterase 4A and 4B are altered by chronic treatment with psychotropic medications in rat frontal cortex. Synapse (New York, N.Y.)\| PubMed ID: 20222156	2010
Fragile X mental retardation protein levels are decreased in major psychiatric disorders. Schizophrenia research\| PubMed ID: 20727716	2010
The role of fragile X mental retardation protein in major mental disorders. Neuropharmacology\| PubMed ID: 21108954	2011
The viral theory of schizophrenia revisited: abnormal placental gene expression and structural changes with lack of evidence for H1N1 viral presence in placentae of infected mice or brains o... Neuropharmacology\| PubMed ID: 21277874	2012
Deficits in GABA(B) receptor system in schizophrenia and mood disorders: a postmortem study. Schizophrenia research\| PubMed ID: 21303731	2011
Dysregulation of fragile × mental retardation protein and metabotropic glutamate receptor 5 in superior frontal cortex of individuals with autism: a postmortem brain study. Molecular autism\| PubMed ID: 21548960	2011
Metabotropic glutamate receptor 5 upregulation in children with autism is associated with underexpression of both Fragile X mental retardation protein and GABAA receptor beta 3 in adults wit... Anatomical record (Hoboken, N.J. : 2007)\| PubMed ID: 21901840	2011
Comparative gene expression study of the chronic exposure to clozapine and haloperidol in rat frontal cortex. Schizophrenia research\| PubMed ID: 22154595	2012
A Review of Varenicline's Efficacy and Tolerability in Smoking Cessation Studies in Subjects with Schizophrenia. Journal of addiction research & therapy\| PubMed ID: 22514788	2011
The involvement of Reelin in neurodevelopmental disorders. Neuropharmacology\| PubMed ID: 22981949	2013
Impairment of fragile X mental retardation protein-metabotropic glutamate receptor 5 signaling and its downstream cognates ras-related C3 botulinum toxin substrate 1, amyloid beta A4 precurs... Molecular autism\| PubMed ID: 23803181	2013
Phosphorylated fragile X mental retardation protein at serine 499, is reduced in cerebellar vermis and superior frontal cortex of subjects with autism: implications for fragile X mental reta... Molecular autism\| PubMed ID: 24180586	2013
A review of traditional and novel treatments for seizures in autism spectrum disorder: findings from a systematic review and expert panel. Frontiers in public health\| PubMed ID: 24350200	2013
Downregulation of GABAA receptor protein subunits α6, β2, δ, ε, γ2, θ, and ρ2 in superior frontal cortex of subjects with autism. Journal of autism and developmental disorders\| PubMed ID: 24668190	2014
Existence of monomer and dimer forms of mGluR5, under reducing conditions in studies of postmortem brain in various psychiatric disorders. Schizophrenia research\| PubMed ID: 25043265	2014
GABA receptor subunit distribution and FMRP-mGluR5 signaling abnormalities in the cerebellum of subjects with schizophrenia, mood disorders, and autism. Schizophrenia research\| PubMed ID: 25432637	2015
Protein expression of targets of the FMRP regulon is altered in brains of subjects with schizophrenia and mood disorders. Schizophrenia research\| PubMed ID: 25956630	2015
Neuropathological Mechanisms of Seizures in Autism Spectrum Disorder. Frontiers in neuroscience\| PubMed ID: 27242398	2016
The effects of prenatal H1N1 infection at E16 on FMRP, glutamate, GABA, and reelin signaling systems in developing murine cerebellum. Journal of neuroscience research\| PubMed ID: 27735078	2017
GABA and GABA receptor dysregulation in superior frontal cortex of subjects with schizophrenia and bipolar disorder. Synapse (New York, N.Y.)\| PubMed ID: 28316115	2017
Altered subcellular localization of fragile X mental retardation signaling partners and targets in superior frontal cortex of individuals with schizophrenia. Neuroreport\| PubMed ID: 28902714	2017
Metabotropic glutamate receptor 5 tracer [F]-FPEB displays increased binding potential in postcentral gyrus and cerebellum of male individuals with autism: a pilot PET study. Cerebellum & ataxias\| PubMed ID: 29449954	2018
Quantitative proteomics of forebrain subcellular fractions in fragile X mental retardation 1 knockout mice following acute treatment with 2-Methyl-6-(phenylethynyl)pyridine: Relevance to dev... Synapse (New York, N.Y.)\| PubMed ID: 30176067	2019
Early Chronic Fluoxetine Treatment of Ts65Dn Mice Rescues Synaptic Vesicular Deficits and Prevents Aberrant Proteomic Alterations. Genes\| PubMed ID: 38674386	2024
Quantitative proteomics of dorsolateral prefrontal cortex reveals an early pattern of synaptic dysmaturation in children with idiopathic autism. Cerebral cortex (New York, N.Y. : 1991)\| PubMed ID: 38696595	2024
Targeting the intracellular immune checkpoint CISH with CRISPR-Cas9-edited T cells in patients with metastatic colorectal cancer: a first-in-human, single-centre, phase 1 trial. The Lancet. Oncology\| PubMed ID: 40315882	2025