Yuqin Chen

State Key Laboratory of Respiratory Diseases, The First Affiliated Hospital of Guangzhou Medical University

Affiliated withThe First Affiliated Hospital of Guangzhou Medical University

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Promising therapeutic effects of sodium tanshinone IIA sulfonate towards pulmonary arterial hypertension in patients. Journal of thoracic disease\| PubMed ID: 23585945	2013
Remodeling of rat pulmonary artery induced by chronic smoking exposure. Journal of thoracic disease\| PubMed ID: 24977008	2014
Chronic hypoxia increases TRPC6 expression and basal intracellular Ca2+ concentration in rat distal pulmonary venous smooth muscle. PloS one\| PubMed ID: 25365342	2014
Peroxisome proliferator-activated receptor γ inhibits pulmonary hypertension targeting store-operated calcium entry. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 25391250	2015
Sodium tanshinone IIA sulfonate inhibits hypoxia-induced enhancement of SOCE in pulmonary arterial smooth muscle cells via the PKG-PPAR-γ signaling axis. American journal of physiology. Cell physiology\| PubMed ID: 27194472	2016
Bortezomib alleviates experimental pulmonary hypertension by regulating intracellular calcium homeostasis in PASMCs. American journal of physiology. Cell physiology\| PubMed ID: 27413173	2016
Comparison and evaluation of two different methods to establish the cigarette smoke exposure mouse model of COPD. Scientific reports\| PubMed ID: 29133824	2017
Pharmacological activation of PPARγ inhibits hypoxia-induced proliferation through a caveolin-1-targeted and -dependent mechanism in PASMCs. American journal of physiology. Cell physiology\| PubMed ID: 29351409	2018
Establishment and evaluation of chronic obstructive pulmonary disease model by chronic exposure to motor vehicle exhaust combined with lipopolysaccharide instillation. Experimental physiology\| PubMed ID: 30070749	2018
Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 30358436	2019
Transplantation of Mesenchymal Stem Cells Attenuates Pulmonary Hypertension by Normalizing the Endothelial-to-Mesenchymal Transition. American journal of respiratory cell and molecular biology\| PubMed ID: 31211918	2020
Efficacy and safety of tetramethylpyrazine phosphate on pulmonary hypertension: study protocol for a randomized controlled study. Trials\| PubMed ID: 31842950	2019
Structural and functional definition of the pulmonary vein system in a chronic hypoxia-induced pulmonary hypertension rat model. American journal of physiology. Cell physiology\| PubMed ID: 31940248	2020
Tetramethylpyrazine: A promising drug for the treatment of pulmonary hypertension. British journal of pharmacology\| PubMed ID: 31976548	2020
Correction to: Efficacy and safety of tetramethylpyrazine phosphate on pulmonary hypertension: study protocol for a randomized controlled study. Trials\| PubMed ID: 32228673	2020
A novel rat model of pulmonary hypertension induced by mono treatment with SU5416. Hypertension research : official journal of the Japanese Society of Hypertension\| PubMed ID: 32472112	2020
Altered Airway Microbiota Composition in Patients With Pulmonary Hypertension. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 32921193	2020
PDGF/MEK/ERK axis represses Ca clearance via decreasing the abundance of plasma membrane Ca pump PMCA4 in pulmonary arterial smooth muscle cells. American journal of physiology. Cell physiology\| PubMed ID: 32966125	2021
Dysregulation of BMP9/BMPR2/SMAD signalling pathway contributes to pulmonary fibrosis and pulmonary hypertension induced by bleomycin in rats. British journal of pharmacology\| PubMed ID: 33080042	2021
Mitomycin C induces pulmonary vascular endothelial-to-mesenchymal transition and pulmonary veno-occlusive disease via Smad3-dependent pathway in rats. British journal of pharmacology\| PubMed ID: 33140842	2021
Response to Michiel Alexander de Raaf et al. Hypertension research : official journal of the Japanese Society of Hypertension\| PubMed ID: 33442030	2021
Upregulation of Piezo1 (Piezo Type Mechanosensitive Ion Channel Component 1) Enhances the Intracellular Free Calcium in Pulmonary Arterial Smooth Muscle Cells From Idiopathic Pulmonary Arter... Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 33813851	2021
The causality between CFTR and pulmonary hypertension: insights from Mendelian randomization studies. Hypertension research : official journal of the Japanese Society of Hypertension\| PubMed ID: 34155362	2021
Bufei huoxue capsules in the management of convalescent COVID-19 infection: study protocol for a multicenter, double-blind, and randomized controlled trial. Pulmonary circulation\| PubMed ID: 34394913	2021
Established pulmonary hypertension in rats was reversed by a combination of a HIF-2α antagonist and a p53 agonist. British journal of pharmacology\| PubMed ID: 34599843	2022
Resolvin E1 Attenuates Pulmonary Hypertension by Suppressing Wnt7a/β-Catenin Signaling. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 34689593	2021
Efficacy and safety of Bufei Huoxue capsules in the management of convalescent patients with COVID-19 infection: A multicentre, double-blind, and randomised controlled trial. Journal of ethnopharmacology\| PubMed ID: 34763045	2022
Natural ingredients from Chinese materia medica for pulmonary hypertension. Chinese journal of natural medicines\| PubMed ID: 34844719	2021
LncPTSR Triggers Vascular Remodeling in Pulmonary Hypertension by Regulating [Ca] in Pulmonary Arterial Smooth Muscle Cells. American journal of respiratory cell and molecular biology\| PubMed ID: 35148256	2022
Sodium tanshinone IIA sulfonate enhances the BMP9-BMPR2-Smad1/5/9 signaling pathway in rat pulmonary microvascular endothelial cells and human embryonic stem cell-derived endothelial cells. Biochemical pharmacology\| PubMed ID: 35276216	2022
Visibility, wind speed, and dew point temperature are important factors in SARS-CoV-2 transmissibility. Pulmonary circulation\| PubMed ID: 35514785	2022
Upregulation of mechanosensitive channel Piezo1 involved in high shear stress-induced pulmonary hypertension. Thrombosis research\| PubMed ID: 35988445	2022
The impact of the COVID-19 pandemic on the care of pulmonary hypertension patients outside the Hubei province in China. Pulmonary circulation\| PubMed ID: 36186716	2022
Microbiome and metabolome dysbiosis of the gut-lung axis in pulmonary hypertension. Microbiological research\| PubMed ID: 36202007	2022
Respiratory Microbiome Profile of Pediatric Pulmonary Hypertension Patients Associated With Congenital Heart Disease. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 36353996	2023
Prediction and prognosis of adverse maternal and foetal/neonatal outcomes in pulmonary hypertension: an observational study and nomogram construction. Respiratory research\| PubMed ID: 36376948	2022
Editorial: Calcium and pulmonary hypertension. Frontiers in physiology\| PubMed ID: 36407003	2022
Correction to: Prediction and prognosis of adverse maternal and foetal/neonatal outcomes in pulmonary hypertension: an observational study and nomogram construction. Respiratory research\| PubMed ID: 36611163	2023
Piezo1, a novel therapeutic target to treat pulmonary arterial hypertension. Frontiers in physiology\| PubMed ID: 36776977	2023
Airway delivery of Streptococcus salivarius is sufficient to induce experimental pulmonary hypertension in rats. British journal of pharmacology\| PubMed ID: 36869838	2023
Bufei huoxue capsule alleviates bleomycin-induced pulmonary fibrosis in mice via TGF-β1/Smad2/3 signaling. Journal of ethnopharmacology\| PubMed ID: 37277082	2023
Echocardiographic evaluation of right heart failure which might be associated with DNA damage response in SU5416-hypoxia induced pulmonary hypertension rat model. Respiratory research\| PubMed ID: 37592245	2023
Endothelium-specific SIRT7 targeting ameliorates pulmonary hypertension through Krüpple-like factor 4 deacetylation. Cardiovascular research\| PubMed ID: 38198357	2024
Non-invasive estimation of pulmonary hypertension and clinical deterioration risk in pediatric congenital heart disease: Development and validation of predictive tools. Chinese medical journal\| PubMed ID: 38595105	2024
Prediction of clinical risk assessment and survival in chronic obstructive pulmonary disease with pulmonary hypertension. Clinical and translational medicine\| PubMed ID: 38861300	2024
Integrated approach of network pharmacology, molecular docking, and clinical observations in evaluating the efficacy and safety of Bufei Huoxue capsules for pulmonary hypertension associated... Pulmonary circulation\| PubMed ID: 39035784	2024
Nephrectomy and high-salt diet inducing pulmonary hypertension and kidney damage by increasing Ang II concentration in rats. Respiratory research\| PubMed ID: 39080603	2024
Estrogen Oppositely Regulates Pulmonary Hypertension via METTL3/PFKFB3 under Normoxia and Hypoxia. American journal of respiratory cell and molecular biology\| PubMed ID: 39265182	2025
The role of Keap1-Nrf2 signaling pathway in the treatment of respiratory diseases and the research progress on targeted drugs. Heliyon\| PubMed ID: 39309822	2024
A study on the genetic comorbidity between autoimmune diseases and pulmonary hypertension: an observational study and POST-GWAS analysis. International journal of medical sciences\| PubMed ID: 40084256	2025
Characteristics and sex differences in bronchopulmonary dysplasia-related pulmonary hypertension. BMC pulmonary medicine\| PubMed ID: 40169967	2025
A Subgroup Reanalysis of the Efficacy of Bufei Huoxue Capsules in Patients With "Long-Covid-19". Pulmonary circulation\| PubMed ID: 40291435	2025