Carolyn J. Baglole

Meakins-Christie Laboratories

Affiliated withMeakins-Christie Laboratories McGill University Research Institute of the McGill University Heath Centre

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 1	2025
Publication title Cited by 1	2025

Other Publications

Article	Year
Lung-targeted overexpression of the NF-κB member RelB inhibits cigarette smoke-induced inflammation. The American journal of pathology\| PubMed ID: 21703398	2011
Genetic ablation of the aryl hydrocarbon receptor causes cigarette smoke-induced mitochondrial dysfunction and apoptosis. The Journal of biological chemistry\| PubMed ID: 21984831	2011
Genetic and histologic evidence for autophagy in asthma pathogenesis. The Journal of allergy and clinical immunology\| PubMed ID: 22040902	2012
Cigarette smoke increases TLR4 and TLR9 expression and induces cytokine production from CD8(+) T cells in chronic obstructive pulmonary disease. Respiratory research\| PubMed ID: 22070100	2011
Autocrine-regulated airway smooth muscle cell migration is dependent on IL-17-induced growth-related oncogenes. The Journal of allergy and clinical immunology\| PubMed ID: 22698519	2012
Th17-associated cytokines promote human airway smooth muscle cell proliferation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 22898922	2012
IL-8 production in response to cigarette smoke is decreased in epithelial cells from COPD patients. Pulmonary pharmacology & therapeutics\| PubMed ID: 23499888	2013
Differential roles of CXCL2 and CXCL3 and their receptors in regulating normal and asthmatic airway smooth muscle cell migration. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23904157	2013
Genetic deletion of IL-17A reduces cigarette smoke-induced inflammation and alveolar type II cell apoptosis. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 24097560	2014
The NF-κB family member RelB regulates microRNA miR-146a to suppress cigarette smoke-induced COX-2 protein expression in lung fibroblasts. Toxicology letters\| PubMed ID: 24472607	2014
Aryl hydrocarbon receptor (AhR) attenuation of subchronic cigarette smoke-induced pulmonary neutrophilia is associated with retention of nuclear RelB and suppression of intercellular adhesio... Toxicological sciences : an official journal of the Society of Toxicology\| PubMed ID: 24752502	2014
Aryl hydrocarbon receptor-dependent regulation of miR-196a expression controls lung fibroblast apoptosis but not proliferation. Toxicology and applied pharmacology\| PubMed ID: 25178717	2014
Alterations in the expression of the NF-κB family member RelB as a novel marker of cardiovascular outcomes during acute exacerbations of chronic obstructive pulmonary disease. PloS one\| PubMed ID: 25409035	2014
Upregulation of IL-17A/F from human lung tissue explants with cigarette smoke exposure: implications for COPD. Respiratory research\| PubMed ID: 25427574	2014
Decreased expression of the NF-κB family member RelB in lung fibroblasts from Smokers with and without COPD potentiates cigarette smoke-induced COX-2 expression. Respiratory research\| PubMed ID: 25943190	2015
Fibroblast-epithelial cell interactions drive epithelial-mesenchymal transition differently in cells from normal and COPD patients. Respiratory research\| PubMed ID: 26081431	2015
The aryl hydrocarbon receptor suppresses cigarette-smoke-induced oxidative stress in association with dioxin response element (DRE)-independent regulation of sulfiredoxin 1. Free radical biology & medicine\| PubMed ID: 26408075	2015
Club Cell-16 and RelB as Novel Determinants of Arterial Stiffness in Exacerbating COPD Patients. PloS one\| PubMed ID: 26914709	2016
Dihydromethysticin (DHM) Blocks Tobacco Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-Induced O(6)-Methylguanine in a Manner Independent of the Aryl Hydrocarbon Receptor (A... Chemical research in toxicology\| PubMed ID: 27728767	2016
Bioinformatic analysis of microRNA and mRNA Regulation in peripheral blood mononuclear cells of patients with chronic obstructive pulmonary disease. Respiratory research\| PubMed ID: 28057018	2017
Differential Contribution of the Aryl-Hydrocarbon Receptor and Toll-Like Receptor Pathways to IL-8 Expression in Normal and Cystic Fibrosis Airway Epithelial Cells Exposed to . Frontiers in cell and developmental biology\| PubMed ID: 28066767	2016
Aryl hydrocarbon receptor (AhR)-dependent regulation of pulmonary miRNA by chronic cigarette smoke exposure. Scientific reports\| PubMed ID: 28079158	2017
Inhaled Pollutants: The Molecular Scene behind Respiratory and Systemic Diseases Associated with Ultrafine Particulate Matter. International journal of molecular sciences\| PubMed ID: 28125025	2017
RelB attenuates cigarette smoke extract-induced apoptosis in association with transcriptional regulation of the aryl hydrocarbon receptor. Free radical biology & medicine\| PubMed ID: 28254546	2017
Pulmonary and diaphragmatic pathology in collagen type I α1 mutant mice with osteogenesis imperfecta. Pediatric research\| PubMed ID: 29538357	2018
Smoke-induced neuromuscular junction degeneration precedes the fibre type shift and atrophy in chronic obstructive pulmonary disease. The Journal of physiology\| PubMed ID: 29663403	2018
The Aryl Hydrocarbon Receptor and the Maintenance of Lung Health. International journal of molecular sciences\| PubMed ID: 30563036	2018
Endocrine aryl hydrocarbon receptor signaling is induced by moderate cutaneous exposure to ultraviolet light. Scientific reports\| PubMed ID: 31186463	2019
Pulmonary neutrophilia caused by absence of the NF-κB member RelB is dampened by exposure to cigarette smoke. Molecular immunology\| PubMed ID: 31476634	2019
Neutrophils from severe asthmatic patients induce epithelial to mesenchymal transition in healthy bronchial epithelial cells. Respiratory research\| PubMed ID: 31665016	2019
Differential Regulation of the Asthmatic Phenotype by the Aryl Hydrocarbon Receptor. Frontiers in physiology\| PubMed ID: 34744763	2021
Endogenous regulation of the Akt pathway by the aryl hydrocarbon receptor (AhR) in lung fibroblasts. Scientific reports\| PubMed ID: 34848742	2021
Involvement of the ACE2/Ang-(1-7)/MasR Axis in Pulmonary Fibrosis: Implications for COVID-19. International journal of molecular sciences\| PubMed ID: 34884756	2021
HuR drives lung fibroblast differentiation but not metabolic reprogramming in response to TGF-β and hypoxia. Respiratory research\| PubMed ID: 34963461	2021
Role of Human Antigen R (HuR) in the Regulation of Pulmonary ACE2 Expression. Cells\| PubMed ID: 35011584	2021
Differential impact of JUUL flavors on pulmonary immune modulation and oxidative stress responses in male and female mice. Archives of toxicology\| PubMed ID: 35254488	2022
Standardized Cannabis Smoke Extract Induces Inflammation in Human Lung Fibroblasts. Frontiers in pharmacology\| PubMed ID: 35418857	2022
Receptor-mediated effects of Δ -tetrahydrocannabinol and cannabidiol on the inflammatory response of alveolar macrophages. Immunology and cell biology\| PubMed ID: 36510483	2023
Modulation of pulmonary immune function by inhaled cannabis products and consequences for lung disease. Respiratory research\| PubMed ID: 36978106	2023
Differential inflammatory profile in the lungs of mice exposed to cannabis smoke with varying THC:CBD ratio. Archives of toxicology\| PubMed ID: 37179517	2023
Dynamic relationship between the aryl hydrocarbon receptor and long noncoding RNA balances cellular and toxicological responses. Biochemical pharmacology\| PubMed ID: 37597813	2023
Regulation of long non-coding RNA expression by aryl hydrocarbon receptor activation. Toxicology letters\| PubMed ID: 38036013	2024
Sex-specific alterations in pulmonary metabolic, xenobiotic and lipid signalling pathways after e-cigarette aerosol exposure during adolescence in mice. BMJ open respiratory research\| PubMed ID: 39299769	2024
Alveolar macrophage function is impaired following inhalation of berry e-cigarette vapor. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 39312670	2024
Cannabis vaping elicits transcriptomic and metabolomic changes involved in inflammatory, oxidative stress, and cancer pathways in human bronchial epithelial cells. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 39823205	2025
The effect of cannabis-derived terpenes on alveolar macrophage function. Frontiers in toxicology\| PubMed ID: 39958606	2024
Transcriptomic changes in oxidative stress, immunity, and cancer pathways caused by cannabis vapor on alveolar epithelial cells. Cell biology and toxicology\| PubMed ID: 40056285	2025
Aryl hydrocarbon receptor-dependent retention of nuclear HuR suppresses cigarette smoke-induced cyclooxygenase-2 expression independent of DNA-binding. PloS one\| PubMed ID: 24086407	2013
Environmental immune disruptors, inflammation and cancer risk. Carcinogenesis\| PubMed ID: 26106141	2015
Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead. Carcinogenesis\| PubMed ID: 26106142	2015
Nanoengineered silica: Properties, applications and toxicity. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association\| PubMed ID: 28578101	2017
Low levels of the AhR in chronic obstructive pulmonary disease (COPD)-derived lung cells increases COX-2 protein by altering mRNA stability. PloS one\| PubMed ID: 28749959	2017
Human airway branch variation and chronic obstructive pulmonary disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 29339516	2018
Inhalation Toxicology of Vaping Products and Implications for Pulmonary Health. International journal of molecular sciences\| PubMed ID: 32429092	2020
Angiotensin-converting enzyme 2 expression in COPD and IPF fibroblasts: the forgotten cell in COVID-19. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 33112187	2021
The aryl hydrocarbon receptor reduces LC3II expression and controls endoplasmic reticulum stress. American journal of physiology. Lung cellular and molecular physiology\| PubMed ID: 33236922	2021
Investigating the effect of pretreatment with azithromycin on inflammatory mediators in bronchial epithelial cells exposed to cigarette smoke. Experimental lung research\| PubMed ID: 33336605	2021
Aryl hydrocarbon receptor deficiency causes the development of chronic obstructive pulmonary disease through the integration of multiple pathogenic mechanisms. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 33605487	2021
The Aryl Hydrocarbon Receptor Attenuates Acute Cigarette Smoke-Induced Airway Neutrophilia Independent of the Dioxin Response Element. Frontiers in immunology\| PubMed ID: 33659010	2021
Human antigen R promotes lung fibroblast differentiation to myofibroblasts and increases extracellular matrix production. Journal of cellular physiology\| PubMed ID: 33855709	2021
Aberrant Post-Transcriptional Regulation of Protein Expression in the Development of Chronic Obstructive Pulmonary Disease. International journal of molecular sciences\| PubMed ID: 34769392	2021
The Aryl Hydrocarbon Receptor Suppresses Chronic Smoke-Induced Pulmonary Inflammation. Frontiers in toxicology\| PubMed ID: 35295140	2021
Editorial: Role of the Aryl Hydrocarbon Receptor in Immune Modulation. Frontiers in toxicology\| PubMed ID: 35800177	2022
Chronic low-level JUUL aerosol exposure causes pulmonary immunologic, transcriptomic, and proteomic changes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 36694994	2023
Opportunities and Challenges of Kava in Lung Cancer Prevention. International journal of molecular sciences\| PubMed ID: 37298489	2023
E-cigarette exposure causes early pro-atherogenic changes in an inducible murine model of atherosclerosis. Frontiers in toxicology\| PubMed ID: 38164438	2023
Biological Anti-IL-5/IL-5R Therapeutics for Chronic Obstructive Pulmonary Disease (COPD) with Specific Treatable Traits: A Real-World Retrospective Analysis. International journal of chronic obstructive pulmonary disease\| PubMed ID: 38249820	2024
Chronic exposure to E-cigarette aerosols potentiates atherosclerosis in a sex-dependent manner. Toxicology and applied pharmacology\| PubMed ID: 39245079	2024
Flavokavains A- and B-Free Kava Enhances Resilience against the Adverse Health Effects of Tobacco Smoke in Mice. ACS pharmacology & translational science\| PubMed ID: 39539272	2024