pipemat-rs-development-validation-standardized-matlab-pipeline-for

PIPEMAT-RS: Development and Validation of a Standardized MATLAB Pipeline for Resting-State EEG Preprocessing

Electroencephalography (EEG) is a crucial tool in neuroscience research and clinical applications, but raw EEG data often contain noise and artifacts that ...

Universidade de São Paulo

Event-related desynchronisation (ERD) and event-related synchronisation (ERS) reflect pain perception and integration of the nociceptive sensory inputs. This may contribute to the understanding of how neurophysiological markers of Knee Osteoarthritis (KOA) patients can differ from control individuals, which would improve aspects such as prediction and prognosis. We performed a cross-sectional analysis of our cohort study (DEFINE cohort), KOA arm, with 71 patients, compared with 65 control participants. The study aimed to examine possible differences between ERD and ERS in control participants compared to Knee Osteoarthritis (KOA) patients when adjusting for important covariates.

Neuroplasticity changes in knee osteoarthritis (KOA) indexed by event-related desynchronization/synchronization during a motor inhibition task.

Event-related desynchronization (ERD) and event-related synchronization (ERS) are critical neurophysiological phenomena associated with motor execution and inhibitory processes. Their utility spans neurophysiological biomarker research and Brain-Computer Interface (BCI) development. However, standardized frameworks for analyzing ERD and ERS oscillations across motor tasks and frequency ranges remain scarce. This study conducted a cross-sectional analysis of 76 healthy participants from the DEFINE cohort to explore ERD and ERS variations across four motor-related tasks (Motor Execution, Motor Imagery, Active Observation, and Passive Observation) and six frequency bands (Delta, Theta, Low Alpha, High Alpha, Low Beta, and High Beta) using C3 electrode activity. Repeated measures ANOVA revealed task-sensitive ERD and ERS power modulations, with oscillatory responses spanning the 1-30 Hz spectrum. Beta activity exhibited pronounced differences between tasks, highlighting its relevance in motor control, while other bands showed distinct task-dependent variations. These findings underscore the variability in ERD/ERS patterns across different tasks and frequency bands, reinforcing the importance of further research into standardized analytical frameworks. By refining ERD/ERS analyses, our study contributes to developing reference frameworks that can enhance clinical and Brain-Computer Interface (BCI) applications.

Article	Year
Neuroplasticity changes in knee osteoarthritis (KOA) indexed by event-related desynchronization/synchronization during a motor inhibition task. Somatosensory & motor research\| PubMed ID: 36921090	2024
Dynamics of sensorimotor-related brain oscillations: EEG insights from healthy individuals in varied upper limb movement conditions. Experimental brain research\| PubMed ID: 40448829	2025

Ana Castellani

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