a-high-fidelity-porcine-model-orthotopic-heart-transplantation

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

The number of advanced heart failure patients who can receive a heart transplant is limited by a shortage of suitable organ donors. In efforts to expand ...

Duke University Medical Center

Partial heart transplantation (PHT) has emerged as a pioneering approach for treating infants with irreparable heart valve dysfunction. However, the scarcity of suitable donors presents a significant bottleneck to its widespread application. This study introduces and evaluates the novel use of domino and split-root procedures within PHT.

Partial Heart Transplantation Promotes Organ Stewardship: Domino Hearts and Split Roots.

Alpha-gal syndrome from tick bites, due to sensitivity to alpha-gal, can cause severe allergies. Heart valve implants contain alpha-gal, yet alpha-gal syndrome screening is not standard before valve replacement. This study examines perioperative outcomes in patients with alpha-gal antibodies.

Article	Year
Partial Heart Transplantation Promotes Organ Stewardship: Domino Hearts and Split Roots. Annals of thoracic surgery short reports\| PubMed ID: 40098863	2025
Perioperative Outcomes After Bioprosthetic Valve Replacement in Patients Sensitized to Alpha-Gal. Annals of thoracic surgery short reports\| PubMed ID: 40098868	2025

Smith Ngeve

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