Robert J. Coffey

Department of Medicine, Vanderbilt University Medical Center

Affiliated withVanderbilt University Medical Center

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2025

Other Publications

Article	Year
Targeting transforming growth factor alpha expression to discrete loci of the neuroendocrine brain induces female sexual precocity. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 9122266	1997
K-Ras-independent effects of the farnesyl transferase inhibitor L-744,832 on cyclin B1/Cdc2 kinase activity, G2/M cell cycle progression and apoptosis in human pancreatic ductal adenocarcino... Neoplasia (New York, N.Y.)\| PubMed ID: 10935512	2000
Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice. The Journal of clinical investigation\| PubMed ID: 11120752	2000
Overexpression of heparin-binding EGF-like growth factor in mouse pancreas results in fibrosis and epithelial metaplasia. Gastroenterology\| PubMed ID: 12671899	2003
Stromal production of prostacyclin confers an antiapoptotic effect to colonic epithelial cells. Cancer research\| PubMed ID: 12702555	2003
Dysregulation of E-cadherin by oncogenic Ras in intestinal epithelial cells is blocked by inhibiting MAP kinase. American journal of surgery\| PubMed ID: 14599601	2003
Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15064403	2004
Oncogenic Ras dominates overexpression of E-cadherin in malignant transformation of intestinal epithelial cells. Surgery\| PubMed ID: 15300195	2004
Identification of MAGI-3 as a transforming growth factor-alpha tail binding protein. Experimental cell research\| PubMed ID: 15652357	2005
Keratin 19 gene drives Cre recombinase expression throughout the early postimplantation mouse embryo. Genesis (New York, N.Y. : 2000)\| PubMed ID: 15828001	2005
Amphiregulin causes functional downregulation of adherens junctions in psoriasis. The Journal of investigative dermatology\| PubMed ID: 15955087	2005
Differential effects of amphiregulin and TGF-alpha on the morphology of MDCK cells. Experimental cell research\| PubMed ID: 15979068	2005
Lysophosphatidic acid, a disintegrin and metalloprotease-17 and heparin-binding epidermal growth factor-like growth factor in ovarian cancer: the first word, not the last. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 16000554	2005
Ligand-dependent activation of the epidermal growth factor receptor by secondary bile acids in polarizing colon cancer cells. Surgery\| PubMed ID: 16213893	2005
Oncogenic KRAS provides a uniquely powerful and variable oncogenic contribution among RAS family members in the colonic epithelium. Journal of cellular physiology\| PubMed ID: 17133351	2007
Ménétrier disease and gastrointestinal stromal tumors: hyperproliferative disorders of the stomach. The Journal of clinical investigation\| PubMed ID: 17200708	2007
Variability of in situ proteomic profiling and implications for study design in colorectal tumors. International journal of oncology\| PubMed ID: 17549410	2007
Naked2 acts as a cargo recognition and targeting protein to ensure proper delivery and fusion of TGF-alpha containing exocytic vesicles at the lower lateral membrane of polarized MDCK cells. Molecular biology of the cell\| PubMed ID: 17553928	2007
Zebrafish Naked1 and Naked2 antagonize both canonical and non-canonical Wnt signaling. Developmental biology\| PubMed ID: 17689523	2007
Lrp6 is required for convergent extension during Xenopus gastrulation. Development (Cambridge, England)\| PubMed ID: 17965054	2007
TACE/ADAM-17: a component of the epidermal growth factor receptor axis and a promising therapeutic target in colorectal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 18281553	2008
EGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18757723	2008
Multiple mechanisms are responsible for transactivation of the epidermal growth factor receptor in mammary epithelial cells. The Journal of biological chemistry\| PubMed ID: 18782770	2008
Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 19010858	2008
ERBBs in the gastrointestinal tract: recent progress and new perspectives. Experimental cell research\| PubMed ID: 19041864	2009
Identification of early intestinal neoplasia protein biomarkers using laser capture microdissection and MALDI MS. Molecular & cellular proteomics : MCP\| PubMed ID: 19164278	2009
The enterocyte microvillus is a vesicle-generating organelle. The Journal of cell biology\| PubMed ID: 19564407	2009
Transmembrane and soluble isoforms of heparin-binding epidermal growth factor-like growth factor regulate distinct processes in the pancreas. Gastroenterology\| PubMed ID: 19689925	2009
Novel association of APC with intermediate filaments identified using a new versatile APC antibody. BMC cell biology\| PubMed ID: 19845967	2009
p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice. The Journal of clinical investigation\| PubMed ID: 20484816	2010
Volume of preclinical xenograft tumors is more accurately assessed by ultrasound imaging than manual caliper measurements. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine\| PubMed ID: 20498463	2010
Distinguishing Ménétrier's disease from its mimics. Gut\| PubMed ID: 20926644	2010
Dual blockade of the EGFR and COX-2 pathways: a phase II trial of cetuximab and celecoxib in patients with chemotherapy refractory metastatic colorectal cancer. American journal of clinical oncology\| PubMed ID: 21217396	2011
Naked1 antagonizes Wnt signaling by preventing nuclear accumulation of β-catenin. PloS one\| PubMed ID: 21490931	2011
Amphiregulin exosomes increase cancer cell invasion. Current biology : CB\| PubMed ID: 21514161	2011
Adenoma formation following limited ablation of p120-catenin in the mouse intestine. PloS one\| PubMed ID: 21611205	2011
Enterocyte microvillus-derived vesicles detoxify bacterial products and regulate epithelial-microbial interactions. Current biology : CB\| PubMed ID: 22386311	2012
The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor. Cell\| PubMed ID: 22464327	2012
[18F]FLT-PET to predict pharmacodynamic and clinical response to cetuximab therapy in Ménétrier's disease. Annals of nuclear medicine\| PubMed ID: 22821337	2012
Myofibroblast keratinocyte growth factor reduces tight junctional integrity and increases claudin-2 levels in polarized Caco-2 cells. Growth factors (Chur, Switzerland)\| PubMed ID: 22946653	2012
Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS. Molecular & cellular proteomics : MCP\| PubMed ID: 23161513	2013
3'-Deoxy-3'-18F-fluorothymidine PET predicts response to (V600E)BRAF-targeted therapy in preclinical models of colorectal cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 23341544	2013
Helicobacter pylori promotes the expression of Krüppel-like factor 5, a mediator of carcinogenesis, in vitro and in vivo. PloS one\| PubMed ID: 23372710	2013
Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia. Oncogene\| PubMed ID: 23376846	2014
Pathology of rodent models of intestinal cancer: progress report and recommendations. Gastroenterology\| PubMed ID: 23415801	2013
Limits of [18F]-FLT PET as a biomarker of proliferation in oncology. PloS one\| PubMed ID: 23554961	2013
Extracellular vesicles: communication, coercion, and conditioning. Molecular biology of the cell\| PubMed ID: 23630232	2013
Transformation of polarized epithelial cells by apical mistrafficking of epiregulin. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23671122	2013
Malignant transformation of colonic epithelial cells by a colon-derived long noncoding RNA. Biochemical and biophysical research communications\| PubMed ID: 24045012	2013
Trafficking of epidermal growth factor receptor ligands in polarized epithelial cells. Annual review of physiology\| PubMed ID: 24215440	2014
Global phosphotyrosine proteomics identifies PKCδ as a marker of responsiveness to Src inhibition in colorectal cancer. PloS one\| PubMed ID: 24260357	2013
A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 24573549	2014
From wavy hair to naked proteins: the role of transforming growth factor alpha in health and disease. Seminars in cell & developmental biology\| PubMed ID: 24631356	2014
Excess PLAC8 promotes an unconventional ERK2-dependent EMT in colon cancer. The Journal of clinical investigation\| PubMed ID: 24691442	2014
Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis. American journal of physiology. Gastrointestinal and liver physiology\| PubMed ID: 24833705	2014
DIPA-family coiled-coils bind conserved isoform-specific head domain of p120-catenin family: potential roles in hydrocephalus and heterotopia. Molecular biology of the cell\| PubMed ID: 25009281	2014
Using a new Lrig1 reporter mouse to assess differences between two Lrig1 antibodies in the intestine. Stem cell research\| PubMed ID: 25460603	2014
Loss of Lrig1 leads to expansion of Brunner glands followed by duodenal adenomas with gastric metaplasia. The American journal of pathology\| PubMed ID: 25794708	2015
Adenoma-like adenocarcinoma: a subtype of colorectal carcinoma with good prognosis, deceptive appearance on biopsy and frequent KRAS mutation. Histopathology\| PubMed ID: 25913616	2016
LRIG1 Regulates Ontogeny of Smooth Muscle-Derived Subsets of Interstitial Cells of Cajal in Mice. Gastroenterology\| PubMed ID: 25921371	2015
Linking patient outcome to high throughput protein expression data identifies novel regulators of colorectal adenocarcinoma aggressiveness. F1000Research\| PubMed ID: 26097693	2015
KRAS-dependent sorting of miRNA to exosomes. eLife\| PubMed ID: 26132860	2015
Cytometry-based single-cell analysis of intact epithelial signaling reveals MAPK activation divergent from TNF-α-induced apoptosis in vivo. Molecular systems biology\| PubMed ID: 26519361	2015
Ménétrier's Disease: Its Mimickers and Pathogenesis. Journal of pathology and translational medicine\| PubMed ID: 26689786	2016
KRAS-MEK Signaling Controls Ago2 Sorting into Exosomes. Cell reports\| PubMed ID: 27117408	2016
Identification and characterization of EGF receptor in individual exosomes by fluorescence-activated vesicle sorting. Journal of extracellular vesicles\| PubMed ID: 27345057	2016
Micropapillary colorectal carcinoma: clinical, pathological and molecular properties, including evidence of epithelial-mesenchymal transition. Histopathology\| PubMed ID: 27560620	2017
EGF receptor ligands: recent advances. F1000Research\| PubMed ID: 27635238	2016
Impaired coordination between signaling pathways is revealed in human colorectal cancer using single-cell mass cytometry of archival tissue blocks. Science signaling\| PubMed ID: 27729552	2016
Autofluorescence flow sorting of breast cancer cell metabolism. Journal of biophotonics\| PubMed ID: 27730745	2017
Circular RNAs are down-regulated in KRAS mutant colon cancer cells and can be transferred to exosomes. Scientific reports\| PubMed ID: 27892494	2016
Three-dimensional culture system identifies a new mode of cetuximab resistance and disease-relevant genes in colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 28320945	2017
Clustering of integrin α5 at the lateral membrane restores epithelial polarity in invasive colorectal cancer cells. Molecular biology of the cell\| PubMed ID: 28356422	2017
A Chimeric Egfr Protein Reporter Mouse Reveals Egfr Localization and Trafficking In Vivo. Cell reports\| PubMed ID: 28494873	2017
Optimized multiplex immunofluorescence single-cell analysis reveals tuft cell heterogeneity. JCI insight\| PubMed ID: 28570279	2017
Lrig1+ gastric isthmal progenitor cells restore normal gastric lineage cells during damage recovery in adult mouse stomach. Gut\| PubMed ID: 28814482	2018
lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling. Nature medicine\| PubMed ID: 29035371	2017
p120-Catenin is an obligate haploinsufficient tumor suppressor in intestinal neoplasia. The Journal of clinical investigation\| PubMed ID: 29130932	2017
Unsupervised Trajectory Analysis of Single-Cell RNA-Seq and Imaging Data Reveals Alternative Tuft Cell Origins in the Gut. Cell systems\| PubMed ID: 29153838	2018
Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models. Nature medicine\| PubMed ID: 29334372	2018
APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway. Developmental cell\| PubMed ID: 29533772	2018
Interpreting heterogeneity in intestinal tuft cell structure and function. The Journal of clinical investigation\| PubMed ID: 29714721	2018
Mutant KRAS Exosomes Alter the Metabolic State of Recipient Colonic Epithelial Cells. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 29930982	2018
Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 30109253	2018
Diverse Long RNAs Are Differentially Sorted into Extracellular Vesicles Secreted by Colorectal Cancer Cells. Cell reports\| PubMed ID: 30332650	2018
Quantitative assessment of cell population diversity in single-cell landscapes. PLoS biology\| PubMed ID: 30346945	2018
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guideline... Journal of extracellular vesicles\| PubMed ID: 30637094	2018
Blood vessel epicardial substance reduces LRP6 receptor and cytoplasmic β-catenin levels to modulate Wnt signaling and intestinal homeostasis. Carcinogenesis\| PubMed ID: 30689807	2019
Linking ALDH1 and retinoic acid signaling. Oncotarget\| PubMed ID: 30815222	2019
Protein kinase A-mediated phosphorylation of naked cuticle homolog 2 stimulates cell-surface delivery of transforming growth factor-α for epidermal growth factor receptor transactivation. Traffic (Copenhagen, Denmark)\| PubMed ID: 30941853	2019
Reassessment of Exosome Composition. Cell\| PubMed ID: 30951670	2019
Transfer of Functional Cargo in Exomeres. Cell reports\| PubMed ID: 30956133	2019
Targeted mobilization of Lrig1 gastric epithelial stem cell populations by a carcinogenic type IV secretion system. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 31488717	2019
miR-302a Inhibits Metastasis and Cetuximab Resistance in Colorectal Cancer by Targeting NFIB and CD44. Theranostics\| PubMed ID: 31754405	2019
Heterogeneity within Stratified Epithelial Stem Cell Populations Maintains the Oral Mucosa in Response to Physiological Stress. Cell stem cell\| PubMed ID: 31809739	2019
Identification and Characterization of Unique Neutralizing Antibodies to Mouse EGF Receptor. Gastroenterology\| PubMed ID: 31866246	2020
The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution. Cell\| PubMed ID: 32302568	2020
KRAS Mutation-Responsive miR-139-5p inhibits Colorectal Cancer Progression and is repressed by Wnt Signaling. Theranostics\| PubMed ID: 32641995	2020
Combined blockade of EGFR and glutamine metabolism in preclinical models of colorectal cancer. Translational oncology\| PubMed ID: 32652471	2020
Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation. Gastroenterology\| PubMed ID: 32828819	2020
A smooth muscle-derived, Braf-driven mouse model of gastrointestinal stromal tumor (GIST): evidence for an alternative GIST cell-of-origin. The Journal of pathology\| PubMed ID: 32944951	2020
Clinically adaptable polymer enables simultaneous spatial analysis of colonic tissues and biofilms. NPJ biofilms and microbiomes\| PubMed ID: 32973205	2020
Rab13 regulates sEV secretion in mutant KRAS colorectal cancer cells. Scientific reports\| PubMed ID: 32978434	2020
Angiotensin-converting Enzyme 2-containing Small Extracellular Vesicles and Exomeres Bind the Severe Acute Respiratory Syndrome Coronavirus 2 Spike Protein. Gastroenterology\| PubMed ID: 33022277	2021
Molecular Imaging of Inflammation in Osteoarthritis Using a Water-Soluble Fluorocoxib. ACS medicinal chemistry letters\| PubMed ID: 33062167	2020
Murine Intrarectal Instillation of Purified Recombinant Toxins Enables Mechanistic Studies of Pathogenesis. Infection and immunity\| PubMed ID: 33468584	2021
First-in-Human PET Imaging and Estimated Radiation Dosimetry of l-[5-C]-Glutamine in Patients with Metastatic Colorectal Cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 33931465	2022
Cell surface integrin α5ß1 clustering negatively regulates receptor tyrosine kinase signaling in colorectal cancer cells via glycogen synthase kinase 3. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 34037774	2021
Translocator protein-targeted photodynamic therapy for direct and abscopal immunogenic cell death in colorectal cancer. Acta biomaterialia\| PubMed ID: 34329783	2021
Induction of apically mistrafficked epiregulin disrupts epithelial polarity via aberrant EGFR signaling. Journal of cell science\| PubMed ID: 34406412	2021
MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging. Nature methods\| PubMed ID: 34824477	2022
Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets. Nature cell biology\| PubMed ID: 34887515	2021
Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps. Cell\| PubMed ID: 34910928	2021
Depletion of METTL3 alters cellular and extracellular levels of miRNAs containing mA consensus sequences. Heliyon\| PubMed ID: 34934837	2021
Quantifying and correcting slide-to-slide variation in multiplexed immunofluorescence images. Bioinformatics (Oxford, England)\| PubMed ID: 34983062	2022
MIRIAM: A machine and deep learning single-cell segmentation and quantification pipeline for multi-dimensional tissue images. Cytometry. Part A : the journal of the International Society for Analytical Cytology\| PubMed ID: 35084791	2022
Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates mA-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression. Molecular cancer\| PubMed ID: 35279145	2022
Significance of a calcium-binding protein S100A14 expression in colon cancer progression. Journal of gastrointestinal oncology\| PubMed ID: 35284114	2022
A CGA/EGFR/GATA2 positive feedback circuit confers chemoresistance in gastric cancer. The Journal of clinical investigation\| PubMed ID: 35289315	2022
Cancer-Associated Fibroblasts and Squamous Epithelial Cells Constitute a Unique Microenvironment in a Mouse Model of Inflammation-Induced Colon Cancer. Frontiers in oncology\| PubMed ID: 35600339	2022
Human Colon Cancer-Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice. Cancer discovery\| PubMed ID: 35678528	2022
Recent Advances in the Study of Extracellular Vesicles in Colorectal Cancer. Gastroenterology\| PubMed ID: 35724732	2022
Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research. iScience\| PubMed ID: 35958027	2022
Are Supermeres a Distinct Nanoparticle? Journal of extracellular biology\| PubMed ID: 36311879	2022
Electrodeposited magnetic nanoporous membrane for high-yield and high-throughput immunocapture of extracellular vesicles and lipoproteins. Communications biology\| PubMed ID: 36496485	2022
Extracellular vesicles and nanoparticles: emerging complexities. Trends in cell biology\| PubMed ID: 36737375	2023
Comprehensive isolation of extracellular vesicles and nanoparticles. Nature protocols\| PubMed ID: 36914899	2023
Exosomes, microvesicles, and other extracellular vesicles-a Keystone Symposia report. Annals of the New York Academy of Sciences\| PubMed ID: 36961472	2023
Development of Pluoronic nanoparticles of fluorocoxib A for endoscopic fluorescence imaging of colonic adenomas. Journal of biomedical optics\| PubMed ID: 37091910	2023
exRNA-eCLIP intersection analysis reveals a map of extracellular RNA binding proteins and associated RNAs across major human biofluids and carriers. Cell genomics\| PubMed ID: 37228754	2023
Inhibition of the bone morphogenetic protein pathway suppresses tumor growth through downregulation of epidermal growth factor receptor in MEK/ERK-dependent colorectal cancer. Cancer science\| PubMed ID: 37357017	2023
Systematic Assessment of Small RNA Profiling in Human Extracellular Vesicles. Cancers\| PubMed ID: 37444556	2023
Anapole-Assisted Low-Power Optical Trapping of Nanoscale Extracellular Vesicles and Particles. Nano letters\| PubMed ID: 37552655	2023
GammaGateR: semi-automated marker gating for single-cell multiplexed imaging. bioRxiv : the preprint server for biology\| PubMed ID: 37781604	2023
Emerging connections between GPI-anchored proteins and their extracellular carriers in colorectal cancer. Extracellular vesicles and circulating nucleic acids\| PubMed ID: 37840781	2023
Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors. Cell\| PubMed ID: 38065082	2023
Dynamic tuft cell expansion during gastric metaplasia and dysplasia. The journal of pathology. Clinical research\| PubMed ID: 38117182	2024
Inhibition of autocrine HGF maturation overcomes cetuximab resistance in colorectal cancer. Cellular and molecular life sciences : CMLS\| PubMed ID: 38212428	2024
The Hallmarks of Precancer. Cancer discovery\| PubMed ID: 38571435	2024
EVPsort: An Atlas of Small ncRNA Profiling and Sorting in Extracellular Vesicles and Particles. Journal of molecular biology\| PubMed ID: 38604528	2024
An anion exchange membrane sensor detects EGFR and its activity state in plasma CD63 extracellular vesicles from patients with glioblastoma. Communications biology\| PubMed ID: 38830977	2024
GammaGateR: semi-automated marker gating for single-cell multiplexed imaging. Bioinformatics (Oxford, England)\| PubMed ID: 38833684	2024
Extracellular RNA in oncogenesis, metastasis and drug resistance. RNA biology\| PubMed ID: 39107918	2024
Comparison of EV characterization by commercial high-sensitivity flow cytometers and a custom single-molecule flow cytometer. Journal of extracellular vesicles\| PubMed ID: 39140467	2024
5-Fluorouracil treatment represses pseudouridine-containing miRNA export into extracellular vesicles. Journal of extracellular biology\| PubMed ID: 39281020	2024
Consensus tissue domain detection in spatial omics data using multiplex image labeling with regional morphology (MILWRM). Communications biology\| PubMed ID: 39478141	2024
Temporal recording of mammalian development and precancer. Nature\| PubMed ID: 39478207	2024
Extracellular vesicles and nanoparticles at a glance. Journal of cell science\| PubMed ID: 39641198	2024
Integration of lipidomics with targeted, single cell, and spatial transcriptomics defines an unresolved pro-inflammatory state in colon cancer. Gut\| PubMed ID: 39658263	2025
Transfer of and increases 3D growth and invasiveness in recipient cancer cells. Extracellular vesicles and circulating nucleic acids\| PubMed ID: 39697634	2024
Yes-associated protein plays oncogenic roles in human sporadic colorectal adenomas. Carcinogenesis\| PubMed ID: 39977302	2025
Blebbisomes are large, organelle-rich extracellular vesicles with cell-like properties. Nature cell biology\| PubMed ID: 39984653	2025
Multiomic spatial atlas shows deleted in malignant brain tumors 1 (DMBT1) glycoprotein is lost in colonic dysplasia. The Journal of pathology\| PubMed ID: 40026233	2025
Benchmarking Spatial Co-Localization Methods for Single-Cell Multiplex Imaging Data with Applications to High-Grade Serous Ovarian and Triple Negative Breast Cancer. Statistics and data science in imaging\| PubMed ID: 40051984	2025
Dipeptidase-1-knockout mice develop invasive tumors with features of microsatellite-unstable colorectal cancer. JCI insight\| PubMed ID: 40178918	2025