Andrew E. Arrant

Department of Neurology, University of Alabama at Birmingham

Affiliated withUniversity of Alabama at Birmingham

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2025

Other Publications

Article	Year
Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD. The Journal of experimental medicine\| PubMed ID: 25155018	2014
Effects of Exercise on Progranulin Levels and Gliosis in Progranulin-Insufficient Mice. eNeuro\| PubMed ID: 26361634	2015
Rho Kinase Inhibition as a Therapeutic for Progressive Supranuclear Palsy and Corticobasal Degeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 26818518	2016
Progranulin haploinsufficiency causes biphasic social dominance abnormalities in the tube test. Genes, brain, and behavior\| PubMed ID: 27213486	2016
Restoring neuronal progranulin reverses deficits in a mouse model of frontotemporal dementia. Brain : a journal of neurology\| PubMed ID: 28379303	2017
Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 29378861	2018
Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency. Molecular neurodegeneration\| PubMed ID: 29929528	2018
Reduction of microglial progranulin does not exacerbate pathology or behavioral deficits in neuronal progranulin-insufficient mice. Neurobiology of disease\| PubMed ID: 30448285	2019
Behavioral defects associated with amygdala and cortical dysfunction in mice with seeded α-synuclein inclusions. Neurobiology of disease\| PubMed ID: 31837424	2020
Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations. Acta neuropathologica communications\| PubMed ID: 31870439	2019
Elevated levels of extracellular vesicles in progranulin-deficient mice and FTD-GRN Patients. Annals of clinical and translational neurology\| PubMed ID: 33197149	2020
Delivering progranulin to neuronal lysosomes protects against excitotoxicity. The Journal of biological chemistry\| PubMed ID: 34298019	2021
Patients with sporadic FTLD exhibit similar increases in lysosomal proteins and storage material as patients with FTD due to GRN mutations. Acta neuropathologica communications\| PubMed ID: 37118844	2023
Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia. Journal of translational medicine\| PubMed ID: 37322482	2023
Regulation of extracellular progranulin in medial prefrontal cortex. Neurobiology of disease\| PubMed ID: 37838007	2023
Dendritic spine head diameter is reduced in the prefrontal cortex of progranulin haploinsufficient mice. Molecular brain\| PubMed ID: 38840181	2024
Increased levels of extracellular matrix proteins associated with extracellular vesicles from brains of aged mice. Aging cell\| PubMed ID: 39377264	2024