minimally-invasive-anatomic-resection-liver-segment-viii-based-on

Minimally Invasive Anatomic Resection of Liver Segment VIII Based on Portal Territory to Treat Hepatocellular Carcinoma

Hepatectomy is the primary treatment for hepatocellular carcinoma (HCC) and is categorized into anatomical hepatectomy and non-anatomical hepatectomy ...

sequential-portal-vein-ligation-robotic-assisted-hepatectomy

Sequential Portal Vein Ligation and Robotic-Assisted Hepatectomy Following Conversion Therapy for Initially Unresectable Hepatocellular Carcinoma

The goal of this protocol is to present a comprehensive multimodal approach for treating hepatocellular carcinoma (HCC) that is initially considered ...

precision-surgery-minimally-invasive-techniques-for-treatment-complex

Precision Surgery and Minimally Invasive Techniques for the Treatment of Complex Biliary Stones Closely Associated with the Middle Hepatic Vein

Hepatectomy is widely used for complex hepatobiliary stones, but when diseased bile ducts involve adjacent vessels, traditional methods, relying on ...

Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology)

This study investigates the differential expression and the mechanism of long intergenic non-protein coding RNA (LINC) 01857 in hepatocellular carcinoma (HCC) proliferation and apoptosis.

Role of long intergenic non-protein coding RNA 01857 in hepatocellular carcinoma malignancy via the regulation of the microRNA-197-3p/anterior GRadient 2 axis.

This study aimed to examine the role of long non-coding RNA PCED1B antisense RNA 1 (PCED1B-AS1) in the development of hepatocellular carcinoma (HCC).

Long Non-coding RNA PCED1B Antisense RNA 1 Promotes Cell Proliferation and Invasion in Hepatocellular Carcinoma by Regulating the MicroRNA-34a/CD44 Axis.

The prognostic value of baseline bone mineral density (BMD) and posttreatment BMD decrease (BMDD) in non-small cell lung cancer (NSCLC) patients receiving immune checkpoint inhibitor (ICI) treatment remains unclear. We assembled data of 2096 patients with advanced NSCLC from five institutions to develop a combined model incorporating BMD/BMDD and clinical characteristics for noninvasive prognosis prediction. BMD was automatically assessed using a deep learning-based method. Compared with the physiological BMD group and the non-severe BMDD group, the pathological BMD group and the severe BMDD group had shorter progression-free survival (PFS) (hazard ratio [HR]: 1.19,  = 0.003; and HR: 1.19,  = 0.002, respectively) and overall survival (OS) (HR: 1.31,  < 0.001; and HR: 1.30,  < 0.001). Compared with the single BMD/BMDD model, the combined model had higher Harrell's concordance indexes (-indexes) (PFS: 0.580 and OS: 0.654). Transcriptomic analysis of 130 patients from the NSCLC radiogenomic cohort revealed upregulation of epithelial-mesenchymal transition, inflammatory, and hypoxia pathways, and increased macrophage infiltration in tumors of patients with pathological BMD. This study showed that lower baseline BMD and more severe BMDD are associated with poorer prognosis. BMD in combination with clinical characteristics can help to improve risk stratification and prognosis prediction.

A Combined Model Based on Bone Mineral Density for Noninvasive Prediction of Prognosis in Non-Small Cell Lung Cancer Patients Receiving Immune Checkpoint Inhibitors: A Multicenter Retrospective Study.

ArticleTotal : 3	Year
Publication title Cited by 1	2025
Publication title	2026
Publication title	2026

Article	Year
Role of long intergenic non-protein coding RNA 01857 in hepatocellular carcinoma malignancy via the regulation of the microRNA-197-3p/anterior GRadient 2 axis. PloS one\| PubMed ID: 34793477	2021
Long Non-coding RNA PCED1B Antisense RNA 1 Promotes Cell Proliferation and Invasion in Hepatocellular Carcinoma by Regulating the MicroRNA-34a/CD44 Axis. Current medical science\| PubMed ID: 38748366	2024
A Combined Model Based on Bone Mineral Density for Noninvasive Prediction of Prognosis in Non-Small Cell Lung Cancer Patients Receiving Immune Checkpoint Inhibitors: A Multicenter Retrospect... MedComm\| PubMed ID: 40989575	2025

Yusheng Guo

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