Shingo Ishihara

Department of Internal Medicine, Rush University Medical Center

Affiliated withRush University Medical Center Chicago Center on Musculoskeletal Pain

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2025

Other Publications

Article	Year
The Role of Peripheral Nociceptive Neurons in the Pathophysiology of Osteoarthritis Pain. Current osteoporosis reports\| PubMed ID: 26233284	2015
Damage-associated molecular patterns generated in osteoarthritis directly excite murine nociceptive neurons through Toll-like receptor 4. Arthritis & rheumatology (Hoboken, N.J.)\| PubMed ID: 26245312	2015
Therapeutic effects of an anti-ADAMTS-5 antibody on joint damage and mechanical allodynia in a murine model of osteoarthritis. Osteoarthritis and cartilage\| PubMed ID: 26410555	2016
Spinal microglial activation in a murine surgical model of knee osteoarthritis. Osteoarthritis and cartilage\| PubMed ID: 27646532	2017
Chemogenetic Inhibition of Pain Neurons in a Mouse Model of Osteoarthritis. Arthritis & rheumatology (Hoboken, N.J.)\| PubMed ID: 28380690	2017
Visualization of Peripheral Neuron Sensitization in a Surgical Mouse Model of Osteoarthritis by In Vivo Calcium Imaging. Arthritis & rheumatology (Hoboken, N.J.)\| PubMed ID: 28992367	2018
An aggrecan fragment drives osteoarthritis pain through Toll-like receptor 2. JCI insight\| PubMed ID: 29563338	2018
Microarray analyses of the dorsal root ganglia support a role for innate neuro-immune pathways in persistent pain in experimental osteoarthritis. Osteoarthritis and cartilage\| PubMed ID: 31982564	2020
The role of intra-articular neuronal CCR2 receptors in knee joint pain associated with experimental osteoarthritis in mice. Arthritis research & therapy\| PubMed ID: 33827672	2021
Targeting the tamoxifen receptor within sodium channels to block osteoarthritic pain. Cell reports\| PubMed ID: 36001977	2022
Notch signaling is activated in knee-innervating dorsal root ganglia in experimental models of osteoarthritis joint pain. Arthritis research & therapy\| PubMed ID: 37061736	2023
Age-Associated Changes in Knee Osteoarthritis, Pain-Related Behaviors, and Dorsal Root Ganglia Immunophenotyping of Male and Female Mice. Arthritis & rheumatology (Hoboken, N.J.)\| PubMed ID: 37096632	2023
Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis. Nature communications\| PubMed ID: 37120427	2023
Reduced capsaicin-induced mechanical allodynia and neuronal responses in the dorsal root ganglion in the presence of protein tyrosine phosphatase non-receptor type 6 overexpression. Molecular pain\| PubMed ID: 38752471	2024
A standardized approach to evaluation and reporting of synovial histopathology in two surgically induced murine models of osteoarthritis. Osteoarthritis and cartilage\| PubMed ID: 38823432	2024
Clearing-enabled light sheet microscopy as a novel method for three-dimensional mapping of the sensory innervation of the mouse knee. bioRxiv : the preprint server for biology\| PubMed ID: 38853939	2024
Intra-articular sprouting of nociceptors accompanies progressive osteoarthritis: comparative evidence in four murine models. Frontiers in neuroanatomy\| PubMed ID: 39076825	2024
Acute systemic macrophage depletion in osteoarthritic mice alleviates pain-related behaviors and does not affect joint damage. bioRxiv : the preprint server for biology\| PubMed ID: 39229102	2024
Clearing-enabled light sheet microscopy as a novel method for three-dimensional mapping of the sensory innervation of the mouse knee. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 39547819	2025
Acute systemic macrophage depletion in osteoarthritic mice alleviates pain-related behaviors and does not affect joint damage. Arthritis research & therapy\| PubMed ID: 39707543	2024
FM-dye inhibition of Piezo2 relieves acute inflammatory and osteoarthritis knee pain in mice of both sexes. bioRxiv : the preprint server for biology\| PubMed ID: 40166233	2025