Rachel E. Miller

Department of Internal Medicine, Rush University Medical Center

Affiliated withRush University Medical Center Chicago Center on Musculoskeletal Pain

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 2	2025

Other Publications

Article	Year
Intraarticular injection of heparin-binding insulin-like growth factor 1 sustains delivery of insulin-like growth factor 1 to cartilage through binding to chondroitin sulfate. Arthritis and rheumatism\| PubMed ID: 20722014	2010
CCR2 chemokine receptor signaling mediates pain in experimental osteoarthritis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23185004	2012
Genetically Engineered Mouse Models Reveal the Importance of Proteases as Osteoarthritis Drug Targets. Current rheumatology reports\| PubMed ID: 23926636	2013
Effects of Dexamethasone on Mesenchymal Stromal Cell Chondrogenesis and Aggrecanase Activity: Comparison of Agarose and Self-Assembling Peptide Scaffolds. Cartilage\| PubMed ID: 24533173	2013
Osteoarthritis joint pain: the cytokine connection. Cytokine\| PubMed ID: 25066335	2014
Effects of the combination of microfracture and self-assembling Peptide filling on the repair of a clinically relevant trochlear defect in an equine model. The Journal of bone and joint surgery. American volume\| PubMed ID: 25274785	2014
Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification. Osteoarthritis and cartilage\| PubMed ID: 25800415	2015
The Role of Peripheral Nociceptive Neurons in the Pathophysiology of Osteoarthritis Pain. Current osteoporosis reports\| PubMed ID: 26233284	2015
Damage-associated molecular patterns generated in osteoarthritis directly excite murine nociceptive neurons through Toll-like receptor 4. Arthritis & rheumatology (Hoboken, N.J.)\| PubMed ID: 26245312	2015
PCSK6-mediated corin activation is essential for normal blood pressure. Nature medicine\| PubMed ID: 26259032	2015
Therapeutic effects of an anti-ADAMTS-5 antibody on joint damage and mechanical allodynia in a murine model of osteoarthritis. Osteoarthritis and cartilage\| PubMed ID: 26410555	2016
Spinal microglial activation in a murine surgical model of knee osteoarthritis. Osteoarthritis and cartilage\| PubMed ID: 27646532	2017
Nerve growth factor blockade for the management of osteoarthritis pain: what can we learn from clinical trials and preclinical models? Current opinion in rheumatology\| PubMed ID: 27672741	2017
Can we target CCR2 to treat osteoarthritis? The trick is in the timing! Osteoarthritis and cartilage\| PubMed ID: 28189827	2017
Chemogenetic Inhibition of Pain Neurons in a Mouse Model of Osteoarthritis. Arthritis & rheumatology (Hoboken, N.J.)\| PubMed ID: 28380690	2017
Chemokine receptor-7 (CCR7) deficiency leads to delayed development of joint damage and functional deficits in a murine model of osteoarthritis. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 28767178	2018
Is cannabis an effective treatment for joint pain? Clinical and experimental rheumatology\| PubMed ID: 28967368	2017
Current status of nerve growth factor antibodies for the treatment of osteoarthritis pain. Clinical and experimental rheumatology\| PubMed ID: 28967370	2017
Visualization of Peripheral Neuron Sensitization in a Surgical Mouse Model of Osteoarthritis by In Vivo Calcium Imaging. Arthritis & rheumatology (Hoboken, N.J.)\| PubMed ID: 28992367	2018
TRPC5 Does Not Cause or Aggravate Glomerular Disease. Journal of the American Society of Nephrology : JASN\| PubMed ID: 29061651	2018
What is new in pain modification in osteoarthritis? Rheumatology (Oxford, England)\| PubMed ID: 29361112	2018
Peripheral Mechanisms Contributing to Osteoarthritis Pain. Current rheumatology reports\| PubMed ID: 29480410	2018
An aggrecan fragment drives osteoarthritis pain through Toll-like receptor 2. JCI insight\| PubMed ID: 29563338	2018
Osteoarthritis pain: What are we learning from animal models? Best practice & research. Clinical rheumatology\| PubMed ID: 30509413	2017
The nociceptive innervation of the normal and osteoarthritic mouse knee. Osteoarthritis and cartilage\| PubMed ID: 31351964	2019
An emerging role for Toll-like receptors at the neuroimmune interface in osteoarthritis. Seminars in immunopathology\| PubMed ID: 31612243	2019
The innate immune response as a mediator of osteoarthritis pain. Osteoarthritis and cartilage\| PubMed ID: 31862470	2020
Why we should study osteoarthritis pain in experimental models in both sexes. Osteoarthritis and cartilage\| PubMed ID: 31926266	2020
Microarray analyses of the dorsal root ganglia support a role for innate neuro-immune pathways in persistent pain in experimental osteoarthritis. Osteoarthritis and cartilage\| PubMed ID: 31982564	2020
Targeting neurotrophic factors: Novel approaches to musculoskeletal pain. Pharmacology & therapeutics\| PubMed ID: 32311372	2020
Pain-related behaviors and abnormal cutaneous innervation in a murine model of classical Ehlers-Danlos syndrome. Pain\| PubMed ID: 32483055	2020
Basic Mechanisms of Pain in Osteoarthritis: Experimental Observations and New Perspectives. Rheumatic diseases clinics of North America\| PubMed ID: 33781488	2021
The role of intra-articular neuronal CCR2 receptors in knee joint pain associated with experimental osteoarthritis in mice. Arthritis research & therapy\| PubMed ID: 33827672	2021
Neuroimmune interactions and osteoarthritis pain: focus on macrophages. Pain reports\| PubMed ID: 33981927	2021
An update on targets for treating osteoarthritis pain: NGF and TRPV1. Current treatment options in rheumatology\| PubMed ID: 34178580	2020
Can we prevent chronic osteoarthritis pain? A view from the bench. Osteoarthritis and cartilage\| PubMed ID: 34628019	2021
Animal Models of Ehlers-Danlos Syndromes: Phenotype, Pathogenesis, and Translational Potential. Frontiers in genetics\| PubMed ID: 34712265	2021
Pain in the Ehlers-Danlos syndromes: Mechanisms, models, and challenges. American journal of medical genetics. Part C, Seminars in medical genetics\| PubMed ID: 34797601	2021
The Genesis of Pain in Osteoarthritis: Inflammation as a Mediator of Osteoarthritis Pain. Clinics in geriatric medicine\| PubMed ID: 35410677	2022
Targeting the tamoxifen receptor within sodium channels to block osteoarthritic pain. Cell reports\| PubMed ID: 36001977	2022
Notch signaling is activated in knee-innervating dorsal root ganglia in experimental models of osteoarthritis joint pain. Arthritis research & therapy\| PubMed ID: 37061736	2023
Age-Associated Changes in Knee Osteoarthritis, Pain-Related Behaviors, and Dorsal Root Ganglia Immunophenotyping of Male and Female Mice. Arthritis & rheumatology (Hoboken, N.J.)\| PubMed ID: 37096632	2023
Piezo2 expressing nociceptors mediate mechanical sensitization in experimental osteoarthritis. Nature communications\| PubMed ID: 37120427	2023
Analysis of matrisome expression patterns in murine and human dorsal root ganglia. Frontiers in molecular neuroscience\| PubMed ID: 37664243	2023
Molecular pathogenesis of OA pain: Past, present, and future. Osteoarthritis and cartilage\| PubMed ID: 38244717	2024
Synovial fibroblast gene expression is associated with sensory nerve growth and pain in rheumatoid arthritis. Science translational medicine\| PubMed ID: 38598614	2024
Charge-Reversed Exosomes for Targeted Gene Delivery to Cartilage for Osteoarthritis Treatment. Small methods\| PubMed ID: 38607953	2024
Reduced capsaicin-induced mechanical allodynia and neuronal responses in the dorsal root ganglion in the presence of protein tyrosine phosphatase non-receptor type 6 overexpression. Molecular pain\| PubMed ID: 38752471	2024
A standardized approach to evaluation and reporting of synovial histopathology in two surgically induced murine models of osteoarthritis. Osteoarthritis and cartilage\| PubMed ID: 38823432	2024
Clearing-enabled light sheet microscopy as a novel method for three-dimensional mapping of the sensory innervation of the mouse knee. bioRxiv : the preprint server for biology\| PubMed ID: 38853939	2024
Intra-articular sprouting of nociceptors accompanies progressive osteoarthritis: comparative evidence in four murine models. Frontiers in neuroanatomy\| PubMed ID: 39076825	2024
Acute systemic macrophage depletion in osteoarthritic mice alleviates pain-related behaviors and does not affect joint damage. bioRxiv : the preprint server for biology\| PubMed ID: 39229102	2024
Clearing-enabled light sheet microscopy as a novel method for three-dimensional mapping of the sensory innervation of the mouse knee. Journal of orthopaedic research : official publication of the Orthopaedic Research Society\| PubMed ID: 39547819	2025
Revisiting the Synovium as a Structural Correlate of Pain in Osteoarthritis. Arthritis & rheumatology (Hoboken, N.J.)\| PubMed ID: 39679772	2025
Acute systemic macrophage depletion in osteoarthritic mice alleviates pain-related behaviors and does not affect joint damage. Arthritis research & therapy\| PubMed ID: 39707543	2024
FM-dye inhibition of Piezo2 relieves acute inflammatory and osteoarthritis knee pain in mice of both sexes. bioRxiv : the preprint server for biology\| PubMed ID: 40166233	2025
Potential sources of pain in symptomatic degenerative meniscal tear: A narrative review. Osteoarthritis and cartilage open\| PubMed ID: 40487806	2025