James McGrath

Department of Biomedical Engineering, University of Rochester

Affiliated withUniversity of Rochester University of Rochester

Research Area

Biography

James McGrath has not added Biography.
If you are James McGrath and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
The role of substrate curvature in actin-based pushing forces. Current biology : CB\| PubMed ID: 15203003	2004
Formin' new ideas about actin filament generation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15466701	2004
Actin motility: staying on track takes a little more effort. Current biology : CB\| PubMed ID: 15530387	2004
Dynein motility: four heads are better than two. Current biology : CB\| PubMed ID: 16332531	2005
Cell mechanics: filaminA leads the way. Current biology : CB\| PubMed ID: 16682340	2006
Binding between particles and proteins in extracts: implications for microrheology and toxicity. Acta biomaterialia\| PubMed ID: 16701809	2005
Microtubule mechanics: a little flexibility goes a long way. Current biology : CB\| PubMed ID: 16979547	2006
Evidence for actin cytoskeleton-dependent and -independent pathways for RelA/p65 nuclear translocation in endothelial cells. The Journal of biological chemistry\| PubMed ID: 17158457	2007
Sheet migration by wounded monolayers as an emergent property of single-cell dynamics. Journal of cell science\| PubMed ID: 17298977	2007
Charge- and size-based separation of macromolecules using ultrathin silicon membranes. Nature\| PubMed ID: 17301789	2007
Relationships between actin regulatory mechanisms and measurable state variables. Annals of biomedical engineering\| PubMed ID: 17380395	2007
Cell spreading: the power to simplify. Current biology : CB\| PubMed ID: 17502086	2007
Metallization of surface-attached actin networks. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference\| PubMed ID: 17946467	2006
A structure-permeability relationship of ultrathin nanoporous silicon membrane: a comparison with the nuclear envelope. Journal of the American Chemical Society\| PubMed ID: 18324815	2008
Membrane mobility of beta2 integrins and rolling associated adhesion molecules in resting neutrophils. Biophysical journal\| PubMed ID: 18689449	2008
The influence of protein adsorption on nanoparticle association with cultured endothelial cells. Biomaterials\| PubMed ID: 19012960	2009
Recombinant human activated protein C inhibits integrin-mediated neutrophil migration. Blood\| PubMed ID: 19244161	2009
Activated integrin VLA-4 localizes to the lamellipodia and mediates T cell migration on VCAM-1. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19542447	2009
Image correlation microscopy for uniform illumination. Journal of microscopy\| PubMed ID: 20055917	2010
Ion-selective permeability of an ultrathin nanoporous silicon membrane as probed by scanning electrochemical microscopy using micropipet-supported ITIES tips. Analytical chemistry\| PubMed ID: 20690617	2010
Pore size control of ultrathin silicon membranes by rapid thermal carbonization. Nano letters\| PubMed ID: 20839831	2010
High-performance separation of nanoparticles with ultrathin porous nanocrystalline silicon membranes. ACS nano\| PubMed ID: 21043434	2010
Robust antigen-specific humoral immune responses to sublingually delivered adenoviral vectors encoding HIV-1 Env: association with mucoadhesion and efficient penetration of the sublingual ba... Vaccine\| PubMed ID: 21801777	2011
LC/LC-MS/MS of an innovative prostate human epithelial cancer (PHEC) in vitro model system. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 22425387	2012
Opposing roles for RhoH GTPase during T-cell migration and activation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22689994	2012
Dynamics of adhesion molecule domains on neutrophil membranes: surfing the dynamic cell topography. European biophysics journal : EBJ\| PubMed ID: 24113789	2013
High-performance, low-voltage electroosmotic pumps with molecularly thin silicon nanomembranes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24167263	2013
Ultrathin silicon membranes for wearable dialysis. Advances in chronic kidney disease\| PubMed ID: 24206603	2013
Highly porous silicon membranes fabricated from silicon nitride/silicon stacks. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 24623562	2014
Highly permeable silicon membranes for shear free chemotaxis and rapid cell labeling. Lab on a chip\| PubMed ID: 24850320	2014
Endothelial vacuolization induced by highly permeable silicon membranes. Acta biomaterialia\| PubMed ID: 25072618	2014
Influence of silicon dioxide capping layers on pore characteristics in nanocrystalline silicon membranes. Nanotechnology\| PubMed ID: 25590751	2015
Analytical and Finite Element Modeling of Nanomembranes for Miniaturized, Continuous Hemodialysis. Membranes\| PubMed ID: 26729179	2015
Evidence of Staphylococcus Aureus Deformation, Proliferation, and Migration in Canaliculi of Live Cortical Bone in Murine Models of Osteomyelitis. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research\| PubMed ID: 27933662	2017
Nanoporous membrane robustness / stability in small form factor microfluidic filtration system. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference\| PubMed ID: 28268711	2016
DNA Translocations through Nanopores under Nanoscale Preconfinement. Nano letters\| PubMed ID: 29087723	2018
Finite element modeling to analyze TEER values across silicon nanomembranes. Biomedical microdevices\| PubMed ID: 29305767	2018
Ultrathin nanoporous membranes for insulator-based dielectrophoresis. Nanotechnology\| PubMed ID: 29528846	2018
Modification of Nanoporous Silicon Nitride with Stable and Functional Organic Monolayers. Chemistry of materials : a publication of the American Chemical Society\| PubMed ID: 29651199	2017
TEM Tomography of Pores with Application to Computational Nanoscale Flows in Nanoporous Silicon Nitride (NPN). Membranes\| PubMed ID: 29865242	2018
Protein Separation and Hemocompatibility of Nitride Membranes in Microfluidic Filtration Systems. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference\| PubMed ID: 30441657	2018
A silicon nanomembrane platform for the visualization of immune cell trafficking across the human blood-brain barrier under flow. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism\| PubMed ID: 30565961	2019
Ultrathin Dual-Scale Nano- and Microporous Membranes for Vascular Transmigration Models. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 30632319	2019
An in vitro platform for elucidating the molecular genetics of S. aureus invasion of the osteocyte lacuno-canalicular network during chronic osteomyelitis. Nanomedicine : nanotechnology, biology, and medicine\| PubMed ID: 31247310	2019
ULTRATHIN SILICON MEMBRANES FOR IMPROVING EXTRACORPOREAL BLOOD THERAPIES. Proceedings of the ... International Conference on Nanochannels, Microchannels and Minichannels. International Conference on Nanochannels, Microchannels and Minichannels\| PubMed ID: 31602425	2016
Development of isoporous microslit silicon nitride membranes for sterile filtration applications. Biotechnology and bioengineering\| PubMed ID: 31784974	2020
Ultrathin Silicon Membranes for Optical Analysis of Nanoparticle Translocation across a Human Blood-Brain Barrier Model. ACS nano\| PubMed ID: 31914314	2020
Second Generation Nanoporous Silicon Nitride Membranes for High Toxin Clearance and Small Format Hemodialysis. Advanced healthcare materials\| PubMed ID: 31943849	2020
Microvascular Mimetics for the Study of Leukocyte-Endothelial Interactions. Cellular and molecular bioengineering\| PubMed ID: 32175026	2020
Tangential flow microfluidics for the capture and release of nanoparticles and extracellular vesicles on conventional and ultrathin membranes. Advanced materials technologies\| PubMed ID: 32395607	2019
Free Standing, Large-Area Silicon Nitride Membranes for High Toxin Clearance in Blood Surrogate for Small-Format Hemodialysis. Membranes\| PubMed ID: 32517263	2020
Monolithic Fabrication of NPN/SiN Dual Membrane Cavity for Nanopore-based DNA Sensing. Advanced materials interfaces\| PubMed ID: 32577337	2019
Entropic Trapping of DNA with a Nanofiltered Nanopore. ACS applied nano materials\| PubMed ID: 32577609	2019
Identification of Penicillin Binding Protein 4 (PBP4) as a critical factor for Staphylococcus aureus bone invasion during osteomyelitis in mice. PLoS pathogens\| PubMed ID: 33091079	2020
Endothelial cell apicobasal polarity coordinates distinct responses to luminally versus abluminally delivered TNF-α in a microvascular mimetic. Integrative biology : quantitative biosciences from nano to macro\| PubMed ID: 33164044	2020
Brain endothelial tricellular junctions as novel sites for T cell diapedesis across the blood-brain barrier. Journal of cell science\| PubMed ID: 33912914	2021
Cell Wall Biosynthesis Modulates Bone Invasion and Osteomyelitis Pathogenesis. Frontiers in microbiology\| PubMed ID: 34484165	2021
Rapid and specific detection of intact viral particles using functionalized microslit silicon membranes as a fouling-based sensor. The Analyst\| PubMed ID: 34933322	2022
Real time imaging of single extracellular vesicle pH regulation in a microfluidic cross-flow filtration platform. Communications biology\| PubMed ID: 35013561	2022
Studies of Transendothelial Migration for Biological and Drug Discovery. Frontiers in medical technology\| PubMed ID: 35047883	2020
Human Organ-on-a-Chip Microphysiological Systems to Model Musculoskeletal Pathologies and Accelerate Therapeutic Discovery. Frontiers in bioengineering and biotechnology\| PubMed ID: 35360391	2022
Molecular mechanisms underlying the heterogeneous barrier responses of two primary endothelial cell types to sphingosine-1-phosphate. European journal of cell biology\| PubMed ID: 35605366	2022
The Modular µSiM: A Mass Produced, Rapidly Assembled, and Reconfigurable Platform for the Study of Barrier Tissue Models In Vitro. Advanced healthcare materials\| PubMed ID: 35899801	2022
The Modular µSiM Reconfigured: Integration of Microfluidic Capabilities to Study In Vitro Barrier Tissue Models under Flow. Advanced healthcare materials\| PubMed ID: 35953453	2022
Identification of Penicillin Binding Protein 4 (PBP4) Inhibitors. Antibiotics (Basel, Switzerland)\| PubMed ID: 36290009	2022
Sourcing cells for models of human vascular barriers of inflammation. Frontiers in medical technology\| PubMed ID: 36483299	2022
A photonic biosensor-integrated tissue chip platform for real-time sensing of lung epithelial inflammatory markers. Lab on a chip\| PubMed ID: 36594179	2023
A tissue chip with integrated digital immunosensors: In situ brain endothelial barrier cytokine secretion monitoring. Biosensors & bioelectronics\| PubMed ID: 36603283	2023
Silicon Nanomembrane Filtration and Imaging for the Evaluation of Microplastic Entrainment along a Municipal Water Delivery Route. Sustainability\| PubMed ID: 36938128	2020
Modelling a Human Blood-Brain Barrier Co-Culture Using an Ultrathin Silicon Nitride Membrane-Based Microfluidic Device. International journal of molecular sciences\| PubMed ID: 36982697	2023
A computer vision approach for analyzing label free leukocyte trafficking dynamics on a microvascular mimetic. Frontiers in immunology\| PubMed ID: 37033977	2023
High levels of endothelial ICAM-1 prohibit natalizumab mediated abrogation of CD4 T cell arrest on the inflamed BBB under flow in vitro. Journal of neuroinflammation\| PubMed ID: 37221552	2023
Human tendon-on-a-chip for modeling vascular inflammatory fibrosis. Research square\| PubMed ID: 38168335	2023
Sided Stimulation of Endothelial Cells Modulates Neutrophil Trafficking in an In Vitro Sepsis Model. Advanced healthcare materials\| PubMed ID: 38547536	2024
Rapid Assessment of Biomarkers on Single Extracellular Vesicles Using 'Catch and Display' on Ultrathin Nanoporous Silicon Nitride Membranes. bioRxiv : the preprint server for biology\| PubMed ID: 38746341	2024
Ingestion of polyethylene terephthalate microplastic water contaminants by Xenopus laevis tadpoles negatively affects their resistance to ranavirus infection and antiviral immunity. Environmental pollution (Barking, Essex : 1987)\| PubMed ID: 38851377	2024
Understanding Human Health Impacts Following Microplastic Exposure Necessitates Standardized Protocols. Current protocols\| PubMed ID: 39018010	2024
Rapid Assessment of Biomarkers on Single Extracellular Vesicles Using "Catch and Display" on Ultrathin Nanoporous Silicon Nitride Membranes. Small (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 39358943	2024
Pericytes Enrich the Basement Membrane and Reduce Neutrophil Transmigration in an In Vitro Model of Peripheral Inflammation at the Blood-Brain Barrier. Biomaterials research\| PubMed ID: 39363889	2024
Human Tendon-on-a-Chip for Modeling the Myofibroblast Microenvironment in Peritendinous Fibrosis. Advanced healthcare materials\| PubMed ID: 39544139	2025
Fluid flow impacts endothelial-monocyte interactions in a model of vascular inflammatory fibrosis. Scientific reports\| PubMed ID: 39863621	2025