Pietro Campiglia

Department of Pharmacy, University of Salerno

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. Peptides\| PubMed ID: 17482720	2007
Design and microwave-assisted synthesis of novel macrocyclic peptides active at melanocortin receptors: discovery of potent and selective hMC5R receptor antagonists. Journal of medicinal chemistry\| PubMed ID: 18412316	2008
Susceptibility to denaturation of caseins in milk samples for improving protein conformational study and their identification. Natural product research\| PubMed ID: 22978643	2013
Novel α-MSH peptide analogues with broad spectrum antimicrobial activity. PloS one\| PubMed ID: 23626703	2013
DTNQ-Pro, a Mimetic Dipeptide, Sensitizes Human Colon Cancer Cells to 5-Fluorouracil Treatment. Journal of amino acids\| PubMed ID: 23710334	2013
Synthesis, in vitro, and in cell studies of a new series of [indoline-3,2'-thiazolidine]-based p53 modulators. Journal of medicinal chemistry\| PubMed ID: 23802716	2013
Synthesis and cytotoxic activity evaluation of 2,3-thiazolidin-4-one derivatives on human breast cancer cell lines. Bioorganic & medicinal chemistry letters\| PubMed ID: 23860590	2013
Ultra high performance liquid chromatography with ion-trap TOF-MS for the fast characterization of flavonoids in Citrus bergamia juice. Journal of separation science\| PubMed ID: 23922323	2013
Human glioblastoma multiforme: p53 reactivation by a novel MDM2 inhibitor. PloS one\| PubMed ID: 23977270	2013
Novel co-axial prilling technique for the development of core-shell particles as delayed drug delivery systems. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V\| PubMed ID: 24582614	2014
Does GRK-β arrestin machinery work as a "switch on" for GPR17-mediated activation of intracellular signaling pathways? Cellular signalling\| PubMed ID: 24613411	2014
Novel therapeutic targets in metabolic disorders: from the bench to the bedside. TheScientificWorldJournal\| PubMed ID: 24959610	2014
Canned bluefin tuna, an in vitro cardioprotective functional food potentially safer than commercial fish oil based pharmaceutical formulations. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association\| PubMed ID: 24972354	2014
CaMKII protects MKP-1 from proteasome degradation in endothelial cells. Cellular signalling\| PubMed ID: 25007998	2014
Evaluation of anti-inflammatory activity and fast UHPLC-DAD-IT-TOF profiling of polyphenolic compounds extracted from green lettuce (Lactuca sativa L.; var. Maravilla de Verano). Food chemistry\| PubMed ID: 25148972	2015
Simulated gastrointestinal digestion, intestinal permeation and plasma protein interaction of white, green, and black tea polyphenols. Food chemistry\| PubMed ID: 25236233	2015
Flavonoid fraction of Bergamot juice reduces LPS-induced inflammatory response through SIRT1-mediated NF-κB inhibition in THP-1 monocytes. PloS one\| PubMed ID: 25260046	2014
A novel crosstalk between calcium/calmodulin kinases II and IV regulates cell proliferation in myeloid leukemia cells. Cellular signalling\| PubMed ID: 25446257	2015
Combined inhibition of AKT/mTOR and MDM2 enhances Glioblastoma Multiforme cell apoptosis and differentiation of cancer stem cells. Scientific reports\| PubMed ID: 25898313	2015
Targeting the CaMKII/ERK Interaction in the Heart Prevents Cardiac Hypertrophy. PloS one\| PubMed ID: 26110816	2015
Annurca peel extract: from the chemical composition, through the functional activity, to the formulation and characterisation of a topical oil-in-water emulsion. Natural product research\| PubMed ID: 26211432	2016
Flavonoid Fraction of Orange and Bergamot Juices Protect Human Lung Epithelial Cells from Hydrogen Peroxide-Induced Oxidative Stress. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 26221182	2015
Integrating GRK2 and NFkappaB in the Pathophysiology of Cardiac Hypertrophy. Journal of cardiovascular translational research\| PubMed ID: 26224342	2015
Dihydrithieno[2,3-b]naphto-4,9-dione analogues as anticancer agents: Synthesis and in cell pharmacological studies. European journal of medicinal chemistry\| PubMed ID: 26253231	2015
Anti-inflammatory and antioxidant activity of polyphenolic extracts from Lactuca sativa (var. Maravilla de Verano) under different farming methods. Journal of the science of food and agriculture\| PubMed ID: 26777118	2016
Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators. Journal of medicinal chemistry\| PubMed ID: 26847872	2016
Adipose microenvironment promotes triple negative breast cancer cell invasiveness and dissemination by producing CCL5. Oncotarget\| PubMed ID: 27027351	2016
Structure-Activity Study of the Peptides P5U and Urantide by the Development of Analogues Containing Uncoded Amino Acids at Position 9. ChemMedChem\| PubMed ID: 27061352	2016
Morus alba extract modulates blood pressure homeostasis through eNOS signaling. Molecular nutrition & food research\| PubMed ID: 27234065	2016
Oxidative Stress Mediates the Antiproliferative Effects of Nelfinavir in Breast Cancer Cells. PloS one\| PubMed ID: 27280849	2016
Development and Identification of a Novel Anti-HIV-1 Peptide Derived by Modification of the N-Terminal Domain of HIV-1 Integrase. Frontiers in microbiology\| PubMed ID: 27375570	2016
Annurca (Malus pumila Miller cv. Annurca) apple as a functional food for the contribution to a healthy balance of plasma cholesterol levels: results of a randomized clinical trial. Journal of the science of food and agriculture\| PubMed ID: 27571713	2017
Identification of an indol-based derivative as potent and selective varicella zoster virus (VZV) inhibitor. European journal of medicinal chemistry\| PubMed ID: 27639368	2016
Design and Synthesis of New Cell Penetrating Peptides: Diffusion and Distribution Inside the Cornea. Molecular pharmaceutics\| PubMed ID: 27676095	2016
Identification of novel microsomal prostaglandin E synthase-1 (mPGES-1) lead inhibitors from Fragment Virtual Screening. European journal of medicinal chemistry\| PubMed ID: 27688183	2017
Secretory leukoprotease inhibitor is required for efficient quercetin-mediated suppression of TNFα secretion. Oncotarget\| PubMed ID: 27716626	2016
Cellular subtype expression and activation of CaMKII regulate the fate of atherosclerotic plaque. Atherosclerosis\| PubMed ID: 28011257	2017
Antioxidant and antimicrobial properties of traditional green and purple "Napoletano" basil cultivars (Ocimum basilicum L.) from Campania region (Italy). Natural product research\| PubMed ID: 28025898	2017
Dendritic Cells Modulate Iron Homeostasis and Inflammatory Abilities Following Quercetin Exposure. Current pharmaceutical design\| PubMed ID: 28079005	2017
A Healthy Balance of Plasma Cholesterol by a Novel Annurca Apple-Based Nutraceutical Formulation: Results of a Randomized Trial. Journal of medicinal food\| PubMed ID: 28296588	2017
Development of an improved online comprehensive hydrophilic interaction chromatography × reversed-phase ultra-high-pressure liquid chromatography platform for complex multiclass polyphenolic... Journal of separation science\| PubMed ID: 28349602	2017
Bioavailable Citrus sinensis Extract: Polyphenolic Composition and Biological Activity. Molecules (Basel, Switzerland)\| PubMed ID: 28420125	2017
Detailed polyphenolic profiling of Annurca apple (M. pumila Miller cv Annurca) by a combination of RP-UHPLC and HILIC, both hyphenated to IT-TOF mass spectrometry. Food research international (Ottawa, Ont.)\| PubMed ID: 28455027	2015
Urinary Metabolomics in Pediatric Obesity and NAFLD Identifies Metabolic Pathways/Metabolites Related to Dietary Habits and Gut-Liver Axis Perturbations. Nutrients\| PubMed ID: 28492501	2017
Secretory Leukoprotease Inhibitor (Slpi) Expression Is Required for Educating Murine Dendritic Cells Inflammatory Response Following Quercetin Exposure. Nutrients\| PubMed ID: 28684695	2017
Flavonoid Composition of Tarocco (Citrus sinensis L. Osbeck) Clone "Lempso" and Fast Antioxidant Activity Screening by DPPH-UHPLC-PDA-IT-TOF. Phytochemical analysis : PCA\| PubMed ID: 28686312	2017
Lactoferrin-derived Peptides Active towards Influenza: Identification of Three Potent Tetrapeptide Inhibitors. Scientific reports\| PubMed ID: 28878220	2017
Chemical profiling of bioactive constituents in hop cones and pellets extracts by online comprehensive two-dimensional liquid chromatography with tandem mass spectrometry and direct infusion... Journal of separation science\| PubMed ID: 29282870	2018
Peptidome profiles and bioactivity elucidation of buffalo-milk dairy products after gastrointestinal digestion. Food research international (Ottawa, Ont.)\| PubMed ID: 29433190	2018
Citrus aurantium L. dry extracts promote C/ebpβ expression and improve adipocyte differentiation in 3T3-L1 cells. PloS one\| PubMed ID: 29596447	2018
Innovative Nanoparticles Enhance -Palmitoylethanolamide Intraocular Delivery. Frontiers in pharmacology\| PubMed ID: 29643808	2018
Fast Profiling of Natural Pigments in Different Dietary Supplements by DI-FT-ICR and Evaluation of their Antioxidant Potential by Pre-Column DPPH-UHPLC Assay. Molecules (Basel, Switzerland)\| PubMed ID: 29751637	2018
Design, Synthesis, Biological Activity, and Structural Analysis of Lactam-Constrained PTPRJ Agonist Peptides. ChemMedChem\| PubMed ID: 29888867	2018
Identification of a Potent Tryptophan-Based TRPM8 Antagonist With in Vivo Analgesic Activity. Journal of medicinal chemistry\| PubMed ID: 29939028	2018
Antioxidant Properties of Buffalo-Milk Dairy Products: A β-Lg Peptide Released after Gastrointestinal Digestion of Buffalo Ricotta Cheese Reduces Oxidative Stress in Intestinal Epithelial Ce... International journal of molecular sciences\| PubMed ID: 29973491	2018
Annurca Apple Polyphenols Ignite Keratin Production in Hair Follicles by Inhibiting the Pentose Phosphate Pathway and Amino Acid Oxidation. Nutrients\| PubMed ID: 30279339	2018
Aquaporin 9 Contributes to the Maturation Process and Inflammatory Cytokine Secretion of Murine Dendritic Cells. Frontiers in immunology\| PubMed ID: 30386332	2018
Annurca Apple Polyphenols Protect Murine Hair Follicles from Taxane Induced Dystrophy and Hijacks Polyunsaturated Fatty Acid Metabolism toward β-Oxidation. Nutrients\| PubMed ID: 30463345	2018
A Bronze-Tomato Enriched Diet Affects the Intestinal Microbiome under Homeostatic and Inflammatory Conditions. Nutrients\| PubMed ID: 30513801	2018
A Novel Small Peptide Inhibitor of NFB, RH10, Blocks Oxidative Stress-Dependent Phenotypes in Cancer. Oxidative medicine and cellular longevity\| PubMed ID: 30524659	2018
Polyphenolic Extract from Tarocco (Citrus sinensis L. Osbeck) Clone "Lempso" Exerts Anti-Inflammatory and Antioxidant Effects via NF-kB and Nrf-2 Activation in Murine Macrophages. Nutrients\| PubMed ID: 30545010	2018
Novel Potent Decameric Peptide of Spirulina platensis Reduces Blood Pressure Levels Through a PI3K/AKT/eNOS-Dependent Mechanism. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 30595120	2019
A Boost in Mitochondrial Activity Underpins the Cholesterol-Lowering Effect of Annurca Apple Polyphenols on Hepatic Cells. Nutrients\| PubMed ID: 30646510	2019
Identification of an indol-based multi-target kinase inhibitor through phenotype screening and target fishing using inverse virtual screening approach. European journal of medicinal chemistry\| PubMed ID: 30763817	2019
Corrigendum: Aquaporin-9 Contributes to the Maturation Process and Inflammatory Cytokine Secretion of Murine Dendritic Cells. Frontiers in immunology\| PubMed ID: 30873153	2019
Antidiabetic and Cardioprotective Effects of Pharmacological Inhibition of GRK2 in db/db Mice. International journal of molecular sciences\| PubMed ID: 30934608	2019
Yield parameters and antioxidant compounds of tomato fruit: the role of plant defence inducers with or without Cucumber mosaic virus infection. Journal of the science of food and agriculture\| PubMed ID: 31106435	2019
Quercetin-Induced miR-369-3p Suppresses Chronic Inflammatory Response Targeting C/EBP-β. Molecular nutrition & food research\| PubMed ID: 31338984	2019
Online comprehensive hydrophilic interaction chromatography × reversed phase liquid chromatography coupled to mass spectrometry for in depth peptidomic profile of microalgae gastro-intestina... Journal of pharmaceutical and biomedical analysis\| PubMed ID: 31352169	2019
An Efficient Approach to Aromatic Aminomethylation Using Dichloromethane as Methylene Source. Frontiers in chemistry\| PubMed ID: 31457005	2019
In situ gelling alginate-pectin blend particles loaded with Ac2-26: A new weapon to improve wound care armamentarium. Carbohydrate polymers\| PubMed ID: 31590879	2020
Characterization of New TRPM8 Modulators in Pain Perception. International journal of molecular sciences\| PubMed ID: 31703254	2019
-Lactoglobulin Heptapeptide Reduces Oxidative Stress in Intestinal Epithelial Cells and Angiotensin II-Induced Vasoconstriction on Mouse Mesenteric Arteries by Induction of Nuclear Factor Er... Oxidative medicine and cellular longevity\| PubMed ID: 31814866	2019
Synthesis and Pharmacological Characterization of Conformationally Restricted Retigabine Analogues as Novel Neuronal Kv7 Channel Activators. Journal of medicinal chemistry\| PubMed ID: 31815462	2020
Anti-Inflammatory and Antioxidant Properties of Dehydrated Potato-Derived Bioactive Compounds in Intestinal Cells. International journal of molecular sciences\| PubMed ID: 31816826	2019
Inflammation and Oxidative Stress in Chronic Kidney Disease-Potential Therapeutic Role of Minerals, Vitamins and Plant-Derived Metabolites. International journal of molecular sciences\| PubMed ID: 31906008	2019
Indole-3-lactic acid, a metabolite of tryptophan, secreted by Bifidobacterium longum subspecies infantis is anti-inflammatory in the immature intestine. Pediatric research\| PubMed ID: 31945773	2020
Blocks Proliferation in Chronic Myelogenous Leukemia via the BCR-ABL/STAT5 Pathway. Cells\| PubMed ID: 32041350	2020
Ocular Formulation Based on Palmitoylethanolamide-Loaded Nanostructured Lipid Carriers: Technological and Pharmacological Profile. Nanomaterials (Basel, Switzerland)\| PubMed ID: 32046269	2020
New Nutraceutical Combination Reduces Blood Pressure and Improves Exercise Capacity in Hypertensive Patients Via a Nitric Oxide-Dependent Mechanism. Journal of the American Heart Association\| PubMed ID: 32078787	2020
Iron Overload Mimicking Conditions Skews Bone Marrow Dendritic Cells Differentiation into MHCIICD11cCD11bF4/80 Cells. International journal of molecular sciences\| PubMed ID: 32079304	2020
Winnie- Mice: A Spontaneous Model of Colitis-Associated Colorectal Cancer Combining Genetics and Inflammation. International journal of molecular sciences\| PubMed ID: 32340123	2020
Pharmacological inhibition of GRK2 improves cardiac metabolism and function in experimental heart failure. ESC heart failure\| PubMed ID: 32352228	2020
Development of Chitosan/Mannitol Microparticles as Delivery System for the Oral Administration of a Spirulina Bioactive Peptide Extract. Molecules (Basel, Switzerland)\| PubMed ID: 32365705	2020
and Protect Cardiomyocytes from Doxorubicin-Induced Oxidative Stress: Evaluation of Onconutraceutical Potential of Vegetable Smoothies. Antioxidants (Basel, Switzerland)\| PubMed ID: 32370308	2020
The Hepatoprotective Effect of Taurisolo, a Nutraceutical Enriched in Resveratrol and Polyphenols, Involves Activation of Mitochondrial Metabolism in Mice Liver. Antioxidants (Basel, Switzerland)\| PubMed ID: 32403305	2020
L. Dry Extracts Ameliorate Adipocyte Differentiation of 3T3-L1 Cells Exposed to TNFα by Down-Regulating Expression. Nutrients\| PubMed ID: 32481686	2020
Synthesis and Ex Vivo Trans-Corneal Permeation of Penetratin Analogues as Ophthalmic Carriers: Preliminary Results. Pharmaceutics\| PubMed ID: 32756470	2020
Bioactive Polyphenols from Pomegranate Juice Reduce 5-Fluorouracil-Induced Intestinal Mucositis in Intestinal Epithelial Cells. Antioxidants (Basel, Switzerland)\| PubMed ID: 32756489	2020
Viruses in wastewater: occurrence, abundance and detection methods. The Science of the total environment\| PubMed ID: 32758747	2020
Exploration of TRPM8 Binding Sites by β-Carboline-Based Antagonists and Their In Vitro Characterization and In Vivo Analgesic Activities. Journal of medicinal chemistry\| PubMed ID: 32787109	2020
Ethanol Extracts Enhance Re-Epithelialization and Prevent Keratinocytes from Free-Radical Injury. Pharmaceuticals (Basel, Switzerland)\| PubMed ID: 32872510	2020
Role of Endothelial G Protein-Coupled Receptor Kinase 2 in Angioedema. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 32895019	2020
Metabolic profiling, in vitro bioaccessibility and in vivo bioavailability of a commercial bioactive Epilobium angustifolium L. extract. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 32896677	2020
Heparan sulfate binds the extracellular Annexin A1 and blocks its effects on pancreatic cancer cells. Biochemical pharmacology\| PubMed ID: 32998001	2020
Aloe gel-base food products: Chemical, toxicological, and regulatory aspects. Regulatory toxicology and pharmacology : RTP\| PubMed ID: 33221425	2021
Exploiting GRK2 Inhibition as a Therapeutic Option in Experimental Cancer Treatment: Role of p53-Induced Mitochondrial Apoptosis. Cancers\| PubMed ID: 33256128	2020
Prenatal and Early Postnatal Cerebral d-Aspartate Depletion Influences l-Amino Acid Pathways, Bioenergetic processes, and Developmental Brain Metabolism. Journal of proteome research\| PubMed ID: 33274941	2021
Annexin A1 Released in Extracellular Vesicles by Pancreatic Cancer Cells Activates Components of the Tumor Microenvironment, through Interaction with the Formyl-Peptide Receptors. Cells\| PubMed ID: 33353163	2020
Analysis of the metabolic switch induced by the spirulina peptide SP6 in high fat diet ApoE mice model: A direct infusion FT-ICR-MS based approach. Journal of pharmaceutical and biomedical analysis\| PubMed ID: 33387838	2021
Analysis Revealed Potential Anti-SARS-CoV-2 Main Protease Activity by the Zonulin Inhibitor Larazotide Acetate. Frontiers in chemistry\| PubMed ID: 33520943	2020
Iron-Enriched Nutritional Supplements for the 2030 Pharmacy Shelves. Nutrients\| PubMed ID: 33530485	2021
Protective Effect of Pomegranate on Oxidative Stress and Inflammatory Response Induced by 5-Fluorouracil in Human Keratinocytes. Antioxidants (Basel, Switzerland)\| PubMed ID: 33573363	2021
In vivo bioavailability and in vitro toxicological evaluation of the new butyric acid releaser N-(1-carbamoyl-2-phenyl-ethyl) butyramide. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 33761606	2021
Epilobium angustifolium L. extract with high content in oenothein B on benign prostatic hyperplasia: A monocentric, randomized, double-blind, placebo-controlled clinical trial. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 33765581	2021
A Novel Vasoactive Peptide "PG1" from Buffalo Ice-Cream Protects from Angiotensin-Evoked High Blood Pressure. Antioxidants (Basel, Switzerland)\| PubMed ID: 33809389	2021
Characterization of phase I and phase II metabolites of hop (Humulus lupulus L.) bitter acids: In vitro and in vivo metabolic profiling by UHPLC-Q-Orbitrap. Journal of pharmaceutical and biomedical analysis\| PubMed ID: 33984828	2021
Quercetin Administration Suppresses the Cytokine Storm in Myeloid and Plasmacytoid Dendritic Cells. International journal of molecular sciences\| PubMed ID: 34361114	2021
Lipid Nanoparticles Traverse Non-Corneal Path to Reach the Posterior Eye Segment: In Vivo Evidence. Molecules (Basel, Switzerland)\| PubMed ID: 34361825	2021
Nobiletin and Xanthohumol Sensitize Colorectal Cancer Stem Cells to Standard Chemotherapy. Cancers\| PubMed ID: 34439086	2021
Healthberry 865 and Its Related, Specific, Single Anthocyanins Exert a Direct Vascular Action, Modulating Both Endothelial Function and Oxidative Stress. Antioxidants (Basel, Switzerland)\| PubMed ID: 34439440	2021
Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization. European journal of medicinal chemistry\| PubMed ID: 34571172	2021
Lifestyle Habits and Exposure to BPA and Phthalates in Women of Childbearing Age from Northern Italy: A Pilot Study. International journal of environmental research and public health\| PubMed ID: 34574636	2021
Discovery of a Novel Tetrapeptide against Influenza A Virus: Rational Design, Synthesis, Bioactivity Evaluation and Computational Studies. Pharmaceuticals (Basel, Switzerland)\| PubMed ID: 34681184	2021
ANXA1 Contained in EVs Regulates Macrophage Polarization in Tumor Microenvironment and Promotes Pancreatic Cancer Progression and Metastasis. International journal of molecular sciences\| PubMed ID: 34681678	2021
Therapeutic potential of TRPM8 antagonists in prostate cancer. Scientific reports\| PubMed ID: 34853378	2021
Hop-derived fraction rich in beta acids and prenylflavonoids regulates the inflammatory response in dendritic cells differently from quercetin: unveiling metabolic changes by mass spectromet... Food & function\| PubMed ID: 34859812	2021
Overcome Chemoresistance: Biophysical and Structural Analysis of Synthetic FHIT-Derived Peptides. Frontiers in molecular biosciences\| PubMed ID: 34901149	2021
Nutritional Regimes Enriched with Antioxidants as an Efficient Adjuvant for IBD Patients under Infliximab Administration, a Pilot Study. Antioxidants (Basel, Switzerland)\| PubMed ID: 35052642	2022
The Longevity-Associated Variant of BPIFB4 Reduces Senescence in Glioma Cells and in Patients' Lymphocytes Favoring Chemotherapy Efficacy. Cells\| PubMed ID: 35053408	2022
Hydroethanolic Extract of L.: Metabolite Profiling and In Vitro Modulation of Molecular Mechanisms Associated to Cardiometabolic Diseases. Nutrients\| PubMed ID: 35057523	2022
Targeting the ASMase/S1P pathway protects from sortilin-evoked vascular damage in hypertension. The Journal of clinical investigation\| PubMed ID: 35104805	2022
Chemical Composition, Fatty Acid and Mineral Content of Food-Grade White, Red and Black Sorghum Varieties Grown in the Mediterranean Environment. Foods (Basel, Switzerland)\| PubMed ID: 35159586	2022
Ultrasound-Assisted Extraction, Chemical Characterization, and Impact on Cell Viability of Food Wastes Derived from Southern Italy Autochthonous Citrus Fruits. Antioxidants (Basel, Switzerland)\| PubMed ID: 35204168	2022
In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening. International journal of molecular sciences\| PubMed ID: 35216186	2022
Metabolomics-assisted discovery of a new anticancer GLS-1 inhibitor chemotype from a nortopsentin-inspired library: From phenotype screening to target identification. European journal of medicinal chemistry\| PubMed ID: 35286926	2022
Interleukin 1β Blockade Reduces Intestinal Inflammation in a Murine Model of Tumor Necrosis Factor-Independent Ulcerative Colitis. Cellular and molecular gastroenterology and hepatology\| PubMed ID: 35314399	2022
Extra Virgin Olive Oil Extracts of Indigenous Southern Tuscany Cultivar Act as Anti-Inflammatory and Vasorelaxant Nutraceuticals. Antioxidants (Basel, Switzerland)\| PubMed ID: 35326088	2022
Development and application of a fast ultra-high performance liquid chromatography-trapped ion mobility mass spectrometry method for untargeted lipidomics. Journal of chromatography. A\| PubMed ID: 35567813	2022
Untargeted lipidomics reveals specific lipid profiles in COVID-19 patients with different severity from Campania region (Italy). Journal of pharmaceutical and biomedical analysis\| PubMed ID: 35569273	2022
Corrigendum: Overcome Chemoresistance: Biophysical and Structural Analysis of Synthetic FHIT-Derived Peptides. Frontiers in molecular biosciences\| PubMed ID: 35573730	2022
New TRPM8 blockers exert anticancer activity over castration-resistant prostate cancer models. European journal of medicinal chemistry\| PubMed ID: 35598411	2022
Structure-Based Development of SARS-CoV-2 Spike Interactors. International journal of molecular sciences\| PubMed ID: 35628409	2022
MALDI Mass Spectrometry Imaging Highlights Specific Metabolome and Lipidome Profiles in Salivary Gland Tumor Tissues. Metabolites\| PubMed ID: 35736462	2022
Post-COVID Syndrome: The Research Progress in the Treatment of Pulmonary after COVID-19 Infection. Pharmaceutics\| PubMed ID: 35745708	2022
Engineering the polyphenolic biosynthetic pathway stimulates metabolic and molecular changes during fruit ripening in "Bronze" tomato. Horticulture research\| PubMed ID: 35795395	2022
Beyond Retigabine: Design, Synthesis, and Pharmacological Characterization of a Potent and Chemically Stable Neuronal Kv7 Channel Activator with Anticonvulsant Activity. Journal of medicinal chemistry\| PubMed ID: 35972998	2022
Cocoa Extract Provides Protection against 6-OHDA Toxicity in SH-SY5Y Dopaminergic Neurons by Targeting PERK. Biomedicines\| PubMed ID: 36009556	2022
Discovery of Benzo[d]imidazole-6-sulfonamides as Bromodomain and Extra-Terminal Domain (BET) Inhibitors with Selectivity for the First Bromodomain. ChemMedChem\| PubMed ID: 36040095	2022
LIMIT: LIfestyle and Microbiome InTeraction Early Adiposity Rebound in Children, a Study Protocol. Metabolites\| PubMed ID: 36144214	2022
The Metabolomic Profile in Amyotrophic Lateral Sclerosis Changes According to the Progression of the Disease: An Exploratory Study. Metabolites\| PubMed ID: 36144241	2022
Antiviral Peptides as Anti-Influenza Agents. International journal of molecular sciences\| PubMed ID: 36232735	2022
Discovery and Optimization of Indoline-Based Compounds as Dual 5-LOX/sEH Inhibitors: and Anti-Inflammatory Characterization. Journal of medicinal chemistry\| PubMed ID: 36318728	2022
A Food-Grade Method for Enhancing the Levels of Low Molecular Weight Proanthocyanidins with Potentially High Intestinal Bioavailability. International journal of molecular sciences\| PubMed ID: 36362344	2022
A rare loss-of-function genetic mutation suggest a role of dermcidin deficiency in hidradenitis suppurativa pathogenesis. Frontiers in immunology\| PubMed ID: 36544771	2022
Combination of , and Improves Cardiac Functions and Reduces Pro-Inflammatory Biomarkers in Preclinical Models of Short-Term Doxorubicin-Mediated Cardiotoxicity: New Frontiers in Cardioncol... Journal of cardiovascular development and disease\| PubMed ID: 36547420	2022
A Label-Free Proteomic Approach for the Identification of Biomarkers in the Exosome of Endometrial Cancer Serum. Cancers\| PubMed ID: 36551747	2022
New Frontiers on ER Stress Modulation: Are TRP Channels the Leading Actors? International journal of molecular sciences\| PubMed ID: 36613628	2022
In Silico Identification and In Vitro Evaluation of New ABCG2 Transporter Inhibitors as Potential Anticancer Agents. International journal of molecular sciences\| PubMed ID: 36614168	2022
Experimental evidence and clinical implications of Warburg effect in the skeletal muscle of Fabry disease. iScience\| PubMed ID: 36879801	2023
Potential Role of Natural Antioxidant Products in Oncological Diseases. Antioxidants (Basel, Switzerland)\| PubMed ID: 36978952	2023
In Vitro Antimicrobial and Antibiofilm Properties and Bioaccessibility after Oral Digestion of Chemically Characterized Extracts Obtained from × L., L., and Their Combination. Foods (Basel, Switzerland)\| PubMed ID: 37174364	2023
Tetrasubstituted Pyrrole Derivative Mimetics of Protein-Protein Interaction Hot-Spot Residues: A Promising Class of Anticancer Agents Targeting Melanoma Cells. Molecules (Basel, Switzerland)\| PubMed ID: 37241902	2023
Design, Synthesis, and Pharmacological Characterization of a Potent Soluble Epoxide Hydrolase Inhibitor for the Treatment of Acute Pancreatitis. Journal of medicinal chemistry\| PubMed ID: 37334504	2023
Anti-Angiogenic Effects of Natural Compounds in Diet-Associated Hepatic Inflammation. Nutrients\| PubMed ID: 37375652	2023
Dipropyleneglycol Dimethylether, New Green Solvent for Solid-Phase Peptide Synthesis: Further Challenges to Improve Sustainability in the Development of Therapeutic Peptides. Pharmaceutics\| PubMed ID: 37376220	2023
Combination of Chemically Characterized Pomegranate Extract and Hydrophilic Vitamins against Prolonged Fatigue: A Monocentric, Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Nutrients\| PubMed ID: 37447210	2023
A Combination of Polymethoxyflavones from and Prenylflavonoids from Counteracts IL-1β-Induced Differentiated Caco-2 Cells Dysfunction via a Modulation of NF-κB/Nrf2 Activation. Antioxidants (Basel, Switzerland)\| PubMed ID: 37627616	2023
SARS-CoV-2 RNA in Wastewater and Bivalve Mollusk Samples of Campania, Southern Italy. Viruses\| PubMed ID: 37632119	2023
Optimization of microwave-assisted extraction of antioxidant compounds from spring onion leaves using Box-Behnken design. Scientific reports\| PubMed ID: 37691048	2023
Enhanced selective capture of phosphomonoester lipids enabling highly sensitive detection of sphingosine 1-phosphate. Analytical and bioanalytical chemistry\| PubMed ID: 37736841	2023
Multi-omics analysis reveals attenuation of cellular stress by empagliflozin in high glucose-treated human cardiomyocytes. Journal of translational medicine\| PubMed ID: 37742032	2023
Rational Design of Novel Peptidomimetics against Influenza A Virus: Biological and Computational Studies. International journal of molecular sciences\| PubMed ID: 37762571	2023
Infiltrating macrophages amplify doxorubicin-induced cardiac damage: role of catecholamines. Cellular and molecular life sciences : CMLS\| PubMed ID: 37819449	2023
High levels of PD-L1 on platelets of NSCLC patients contributes to the pharmacological activity of Atezolizumab. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 37857253	2023
A Multi-Omics Approach Revealed Common Dysregulated Pathways in Type One and Type Two Endometrial Cancers. International journal of molecular sciences\| PubMed ID: 38003247	2023
Sub-5-min RP-UHPLC-TIMS for high-throughput untargeted lipidomics and its application to multiple matrices. Analytical and bioanalytical chemistry\| PubMed ID: 38078946	2024
Integrated plasma metabolomics and lipidomics profiling highlights distinctive signature of hepatocellular carcinoma in HCV patients. Journal of translational medicine\| PubMed ID: 38110968	2023
Peptidomimetics as potent dual SARS-CoV-2 cathepsin-L and main protease inhibitors: In silico design, synthesis and pharmacological characterization. European journal of medicinal chemistry\| PubMed ID: 38232463	2024
Maternal Exposure to Endocrine-Disrupting Chemicals: Analysis of Their Impact on Infant Gut Microbiota Composition. Biomedicines\| PubMed ID: 38275405	2024
Traceability and authentication in agri-food production: A multivariate approach to the characterization ofthe Italian food excellence elephant garlic (Allium ampeloprasum L.), a vasoactive ... Food chemistry\| PubMed ID: 38359701	2024
Link between organic nanovescicles from vegetable kingdom and human cell physiology: intracellular calcium signalling. Journal of nanobiotechnology\| PubMed ID: 38369472	2024
Identification of Mortalin as the Main Interactor of Mycalin A, a Poly-Brominated C-15 Acetogenin Sponge Metabolite, by MS-Based Proteomics. Marine drugs\| PubMed ID: 38393023	2024
Novel pyrrole based CB2 agonists: New insights on CB2 receptor role in regulating neurotransmitters' tone. European journal of medicinal chemistry\| PubMed ID: 38493727	2024
α acid fraction from Hop extract exerts an endothelium-derived hyperpolarization vasorelaxant effect through TRPV4 employing the feedforward mechanism of PKCα. Food & function\| PubMed ID: 38506030	2024
Antitumor Mechanisms of Fruit: An Overview of In Vitro and In Vivo Potential. Life (Basel, Switzerland)\| PubMed ID: 38541744	2024
The Deep Proteomics Approach Identified Extracellular Vesicular Proteins Correlated to Extracellular Matrix in Type One and Two Endometrial Cancer. International journal of molecular sciences\| PubMed ID: 38731868	2024
Assisted Identification, Synthesis, and Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel. Journal of medicinal chemistry\| PubMed ID: 38782404	2024
Anticancer Therapies Based on Oxidative Damage: Inhibits the Proliferation of MCF-7 Cells by Activating Pyroptosis through Endoplasmic Reticulum Stress. Antioxidants (Basel, Switzerland)\| PubMed ID: 38929147	2024
KCNT1 Channel Blockers: A Medicinal Chemistry Perspective. Molecules (Basel, Switzerland)\| PubMed ID: 38931004	2024
Plasma metabolomic and lipidomic profiles accurately classify mothers of children with congenital heart disease: an observational study. Metabolomics : Official journal of the Metabolomic Society\| PubMed ID: 38955892	2024
TFEB controls syncytiotrophoblast formation and hormone production in placenta. Cell death and differentiation\| PubMed ID: 38965447	2024
A Comprehensive Characterization of a New Class of Indole-Based Compounds Developed as Selective Haspin Inhibitors. Journal of medicinal chemistry\| PubMed ID: 39038808	2024
Fam134c and Fam134b shape axonal endoplasmic reticulum architecture in vivo. EMBO reports\| PubMed ID: 39039299	2024
Inverse FASN and LDHA correlation drives metabolic resistance in breast cancer. Journal of translational medicine\| PubMed ID: 39044184	2024
Voltage-Gated K Channel Modulation by Marine Toxins: Pharmacological Innovations and Therapeutic Opportunities. Marine drugs\| PubMed ID: 39195466	2024
Multiomic Profiling and Neuroprotective Bioactivity of Hairy Root-Derived Extracellular Vesicles in a Cellular Model of Parkinson's Disease. International journal of nanomedicine\| PubMed ID: 39286353	2024
Leveraging the potential of 1.0-mm i.d. columns in UHPLC-HRMS-based untargeted metabolomics. Analytical and bioanalytical chemistry\| PubMed ID: 39443364	2025
Evaluating microplastic emission from takeaway containers: A Micro-Raman approach across diverse exposure scenarios. Food chemistry\| PubMed ID: 39447258	2025
Exploring Endocannabinoid System: Unveiling New Roles in Modulating ER Stress. Antioxidants (Basel, Switzerland)\| PubMed ID: 39594426	2024
5-methyl-2-carboxamidepyrrole-based novel dual mPGES-1/sEH inhibitors as promising anticancer candidates. Archiv der Pharmazie\| PubMed ID: 39692230	2025
Neuroprotective Potential of Indole-Based Compounds: A Biochemical Study on Antioxidant Properties and Amyloid Disaggregation in Neuroblastoma Cells. Antioxidants (Basel, Switzerland)\| PubMed ID: 39765912	2024
A Pilot Study of Exosome Proteomic Profiling Reveals Dysregulated Metabolic Pathways in Endometrial Cancer. Biomedicines\| PubMed ID: 39857679	2025
Furazanopyrazine-based novel promising anticancer agents interfering with the eicosanoid biosynthesis pathways by dual mPGES-1 and sEH inhibition. European journal of medicinal chemistry\| PubMed ID: 40010271	2025
Enhanced visualization of endocannabinoids spatial distribution in mouse brain via MALDI-2 mass spectrometry imaging. Talanta\| PubMed ID: 40015066	2025
Metabolomics insights into the protective molecular mechanism of Vaccinium myrtillus against oxidative stress in intestinal cells. Scientific reports\| PubMed ID: 40082563	2025
Advancing profiling of secondary antioxidant metabolites in Allium cepa PDO leaf extract: Online comprehensive two-dimensional liquid chromatography with high-resolution mass spectrometry an... Journal of chromatography. A\| PubMed ID: 40121955	2025
Targeting the CXCR4/CXCL12 Axis in Cancer Therapy: Analysis of Recent Advances in the Development of Potential Anticancer Agents. Molecules (Basel, Switzerland)\| PubMed ID: 40142155	2025
Computational, crystallographic, and biophysical characterizations provide insights into calcium and phosphate binding by human annexin A4. International journal of biological macromolecules\| PubMed ID: 40157693	2025
Endoplasmic Reticulum Stress and Its Role in Metabolic Reprogramming of Cancer. Metabolites\| PubMed ID: 40278350	2025
A Diet Fortified with Anthocyanin-Rich Extract (RED) Reduces Ileal Inflammation in a Senescence-Prone Mice Model of Crohn's-Disease-like Ileitis. Antioxidants (Basel, Switzerland)\| PubMed ID: 40298846	2025
Novel Para-Phenylenediamine-Based Derivatives as Receptor Tyrosine Kinase-like Orphan Receptor 1 (ROR1) Inhibitors: An In Vitro Preliminary Characterization. ChemMedChem\| PubMed ID: 40328670	2025
Unveiling New Triazoloquinoxaline-Based PROTACs Designed for the Selective Degradation of the ncBAF Chromatin Remodeling Subunit BRD9. Chemistry (Weinheim an der Bergstrasse, Germany)\| PubMed ID: 40343767	2025
Integrated proteomics highlights functional activation induced by advanced-platelet rich fibrin plus (A-PRF +) in primary equine fibroblasts. Scientific reports\| PubMed ID: 40410219	2025
Preserving Neuronal Chemical Messengers: Heat Stabilization Versus Snap Freezing for Improved MALDI Mass Spectrometry Imaging of Brain Tissues. Journal of neurochemistry\| PubMed ID: 40522155	2025