the-design-application-inhibiting-peptide-for-rapid-vitro

The Design and Application of Inhibiting Peptide for Rapid <em>In vitro</em> Downregulation of Post-Translational Modifications Levels at a Specific Site

Proteins are the primary executors of life activities and are regulated at transcriptional, translational, and post-translational modification (PTM) ...

Nanjing Medical University

BIN2 inhibition suppress ovarian cancer progression meanwhile protect ovarian function through downregulating HDAC1 and RPS6 phosphorylation respectively.

Members of the nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing (NLRP) family regulate various physiological and pathological processes. However, none have been shown to regulate actin cap formation or spindle translocation during the asymmetric division of oocyte meiosis I. NLRP4E has been reported as a candidate protein in female fertility, but its function is unknown.

Article	Year
BIN2 inhibition suppress ovarian cancer progression meanwhile protect ovarian function through downregulating HDAC1 and RPS6 phosphorylation respectively. Clinical and translational medicine\| PubMed ID: 39412213	2024
NLRP4E regulates actin cap formation through SRC and CDC42 during oocyte meiosis. Cellular & molecular biology letters\| PubMed ID: 38730334	2024

Shu-Ping Zhang

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