ye-s-swing-technique-for-small-incision-lenticule-extraction-surgery

Ye's Swing Technique for Small-incision Lenticule Extraction Surgery

We propose a novel approach for small incision lenticule extraction (SMILE) surgery, termed the Ye's Swing Technique. The separation and removal of the ...

Wenzhou Medical University

Achromatopsia (ACHM) is a severe congenital autosomal recessive retinal disorder caused by loss of cone photoreceptors. Here, we aimed to determine the underlying genetic lesions and phenotypic correlations in two Chinese families with ACHM.

Identification of novel mutations by targeted exome sequencing and the genotype-phenotype assessment of patients with achromatopsia.

Complement factor H (CFH) related proteins (CFHRs) play important roles in complement activation pathways, whereas previous studies have only shown that CFH can affect the development of uveitis. In the present study, we investigated the potential associations between one of single-nucleotide polymorphisms in the CFHR2 gene with acute anterior uveitis (AAU).

CFHR2-rs2986127 as a genetic protective marker for acute anterior uveitis in Chinese patients.

Inherited retinal diseases (IRDs) are a clinically and genetically heterogeneous group of Mendelian disorders that plays a crucial role in the etiology of blindness across the world. Molecular genetic diagnosis of IRD remains extremely complex and challenging because mutations are only detected in 40% to 60% of cases. In this study, we aimed to dissect the contributions of copy number variations (CNVs) in IRD patients.

Genome-Wide Detection of Copy Number Variations in Unsolved Inherited Retinal Disease.

(1) To compare the efficacy of continued and stopping treatment for 0.05%, 0.025%, and 0.01% atropine during the third year. (2) To evaluate the efficacy of continued treatment over 3 years. (3) To investigate the rebound phenomenon and its determinants after cessation of treatment.

Three-Year Clinical Trial of Low-Concentration Atropine for Myopia Progression (LAMP) Study: Continued Versus Washout: Phase 3 Report.

Congenital cataract-microcornea syndrome (CCMC) is characterized by the association of congenital cataract and microcornea without any other systemic anomaly or dysmorphism. Although several causative genes have been reported in patients with CCMC, the genetic etiology of CCMC is yet to be clearly understood.

Novel SOX2 mutation in autosomal dominant cataract-microcornea syndrome.

This study aimed to evaluate the lenticule integrity and refractive outcomes of a new technique, Ye's swing technique, during small-incision lenticule extraction (SMILE).

Modified Technique for Small-Incision Lenticule Extraction: Ye's Swing Technique.

Little is known about whether sugar intake is a risk factor for myopia, and the influence of glycemic control remains unclear, with inconsistent results reported. This study aimed to clarify this uncertainty by evaluating the link between multiple glycemic traits and myopia.

Causal Relationships Between Glycemic Traits and Myopia.

We aimed to investigate the causal association between , an immune checkpoint inhibitor, and anterior uveitis (AU), as well as associated systemic immune diseases.

Association of  with anterior uveitis and associated systemic immune diseases: a Mendelian randomization analysis.

Age-related macular degeneration (AMD) is one of the major causes of vision loss. Early AMD needs to be taken seriously, but the causal effects of lipid biomarkers on early AMD remain unclear.

Causal effects of serum lipid biomarkers on early age-related macular degeneration using Mendelian randomization.

To compare astigmatic correction among cross-assisted small-incision lenticule extraction (SMILE), femtosecond laser-assisted in situ keratomileusis (FS-LASIK), and transepithelial photorefractive keratectomy (transPRK).

Comparison of myopic astigmatic correction after cross-assisted SMILE, FS-LASIK, and transPRK.

Observational studies have shown that sleep pattern is associated with age-related macular degeneration (AMD), but whether sleep pattern is a causal factor for AMD remains unclear. This study aims to use Mendelian randomization (MR) analysis to investigate the potential causal relationship between sleep traits and AMD.

Minimal effect of sleep on the risk of age-related macular degeneration: a Mendelian randomization study.

This study aims to assess the accuracy of three parameters (white-to-white distance [WTW], angle-to-angle [ATA], and sulcus-to-sulcus [STS]) in predicting postoperative vault and to formulate an optimized predictive model.

Predictability comparison of sizing parameters for postoperative vault after implantable Collamer lens implantation.

Myopia, especially high myopia (HM), represents a widespread visual impairment with a globally escalating prevalence. This study aimed to elucidate the genetic foundations associated with early-onset HM (eoHM) while delineating the genetic landscape specific to Shaanxi province, China.

Trio-based whole-exome sequencing reveals mutations in early-onset high myopia.

To determine the factors related to preoperative ocular characters that are predictive of insufficient vault (<250 µm) after implantable collamer lens (ICL V4c; STAAR Surgical) implantation.

Clinical prediction of insufficient vaults after implantable collamer lens implantation.

Artificial intelligence (AI) models are effective for analyzing high-quality slit-lamp images but often face challenges in real-world clinical settings due to image variability. This study aims to develop and evaluate a hybrid AI-based image quality control system to classify slit-lamp images, improving diagnostic accuracy and efficiency, particularly in telemedicine applications.

Article	Year
Identification of novel mutations by targeted exome sequencing and the genotype-phenotype assessment of patients with achromatopsia. Journal of translational medicine\| PubMed ID: 26493561	2015
CFHR2-rs2986127 as a genetic protective marker for acute anterior uveitis in Chinese patients. The journal of gene medicine\| PubMed ID: 27306586	2016
Genome-Wide Detection of Copy Number Variations in Unsolved Inherited Retinal Disease. Investigative ophthalmology & visual science\| PubMed ID: 28118666	2017
Three-Year Clinical Trial of Low-Concentration Atropine for Myopia Progression (LAMP) Study: Continued Versus Washout: Phase 3 Report. Ophthalmology\| PubMed ID: 34627809	2022
Novel SOX2 mutation in autosomal dominant cataract-microcornea syndrome. BMC ophthalmology\| PubMed ID: 35148715	2022
Modified Technique for Small-Incision Lenticule Extraction: Ye's Swing Technique. Ophthalmology and therapy\| PubMed ID: 36402902	2023
Causal Relationships Between Glycemic Traits and Myopia. Investigative ophthalmology & visual science\| PubMed ID: 36867130	2023
Association of with anterior uveitis and associated systemic immune diseases: a Mendelian randomization analysis. Frontiers in medicine\| PubMed ID: 37396905	2023
Causal effects of serum lipid biomarkers on early age-related macular degeneration using Mendelian randomization. Genes & nutrition\| PubMed ID: 37479984	2023
Comparison of myopic astigmatic correction after cross-assisted SMILE, FS-LASIK, and transPRK. Journal of cataract and refractive surgery\| PubMed ID: 37616187	2023
Minimal effect of sleep on the risk of age-related macular degeneration: a Mendelian randomization study. Frontiers in aging neuroscience\| PubMed ID: 37671084	2023
Predictability comparison of sizing parameters for postoperative vault after implantable Collamer lens implantation. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie\| PubMed ID: 38376562	2024
Trio-based whole-exome sequencing reveals mutations in early-onset high myopia. BMJ open ophthalmology\| PubMed ID: 38789272	2024
Clinical prediction of insufficient vaults after implantable collamer lens implantation. International journal of ophthalmology\| PubMed ID: 39026913	2024
Integrating prior knowledge with deep learning for optimized quality control in corneal images: A multicenter study. Computer methods and programs in biomedicine\| PubMed ID: 40319841	2025

Fen-Fen Li

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