Azmat Ali Khan

Pharmaceutical Biotechnology Laboratory, King Saud University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
Design, synthesis and in vitro anticancer evaluation of a stearic acid-based ester conjugate. Anticancer research\| PubMed ID: 23749903	2013
Molecular modeling and analysis of hepatitis E virus (HEV) papain-like cysteine protease. Virus research\| PubMed ID: 24321124	2014
Targeting HER-2 over expressed breast cancer cells with 2-cyclohexyl-N-[(Z)-(substituted phenyl/furan-2-yl/thiophene-2-yl)methylidene]hydrazinecarbothioamide. Bioorganic & medicinal chemistry letters\| PubMed ID: 25466196	2015
Effect of some plants' extracts used in Sudanese folkloric medicines on carrageenan-induced inflammation. Pakistan journal of pharmaceutical sciences\| PubMed ID: 25553680	2015
Biophysical Interactions of Novel Oleic Acid Conjugate and its Anticancer Potential in HeLa Cells. Journal of fluorescence\| PubMed ID: 25638605	2015
Synthesis and characterization of 2-substituted benzimidazoles and their evaluation as anticancer agent. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy\| PubMed ID: 25706598	2015
Erratum to: Biophysical Interactions of Novel Oleic Acid Conjugate and its Anticancer Potential in HeLa Cells. Journal of fluorescence\| PubMed ID: 25808595	2015
Lead Optimization of 2-Cyclohexyl-N-[(Z)-(3-methoxyphenyl/3-hydroxyphenyl) methylidene]hydrazinecarbothioamides for Targeting the HER-2 Overexpressed Breast Cancer Cell Line SKBr-3. Molecules (Basel, Switzerland)\| PubMed ID: 26457700	2015
Targeted nano-delivery of novel omega-3 conjugate against hepatocellular carcinoma: Regulating COX-2/bcl-2 expression in an animal model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 27261618	2016
Antifungal efficacy of amphotericin B encapsulated fibrin microsphere for treating Cryptococcus neoformans infection in Swiss albino mice. The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases\| PubMed ID: 27294976	2016
In vitro evaluation of cytotoxicity, possible alteration of apoptotic regulatory proteins, and antibacterial activity of synthesized copper oxide nanoparticles. Colloids and surfaces. B, Biointerfaces\| PubMed ID: 28285257	2017
Pro-apoptotic activity of nano-escheriosome based oleic acid conjugate against 7,12-dimethylbenz(a)anthracene (DMBA) induced cutaneous carcinogenesis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie\| PubMed ID: 28364601	2017
New constituents triterpene ester and sugar derivatives from Meyer and their evaluation of antioxidant activities. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society\| PubMed ID: 28725154	2017
Comparative anticancer and antimicrobial activity of aerial parts of , , and grown in Saudi Arabia. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society\| PubMed ID: 29204075	2017
Restrained management of copper level enhances the antineoplastic activity of imatinib in vitro and in vivo. Scientific reports\| PubMed ID: 29374195	2018
Fungal biofilm inhibition by piperazine-sulphonamide linked Schiff bases: Design, synthesis, and biological evaluation. Archiv der Pharmazie\| PubMed ID: 29543339	2018
Additive potential of combination therapy against cryptococcosis employing a novel amphotericin B and fluconazole loaded dual delivery system. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 29653177	2018
Design, Synthesis, and Biological Evaluation of Benzimidazole-Derived Biocompatible Copper(II) and Zinc(II) Complexes as Anticancer Chemotherapeutics. International journal of molecular sciences\| PubMed ID: 29772746	2018
Evaluation of Transition Metal Complexes of Benzimidazole-Derived Scaffold as Promising Anticancer Chemotherapeutics. Molecules (Basel, Switzerland)\| PubMed ID: 29883398	2018
Interspecies Anticancer and Antimicrobial Activities of Genus and Estimation of Rutin by Validated UPLC-PDA Method. Evidence-based complementary and alternative medicine : eCAM\| PubMed ID: 30057644	2018
Hepatitis B virus precore G1896A mutation in chronic liver disease patients with HBeAg negative serology from North India. Saudi journal of biological sciences\| PubMed ID: 30505167	2018
Preparation, characterizations and in vitro cytotoxic activity of nickel oxide nanoparticles on HT-29 and SW620 colon cancer cell lines. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS)\| PubMed ID: 30732872	2019
Evaluation of Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Poorly Water-Soluble Talinolol: Preparation, and Assessment. Frontiers in pharmacology\| PubMed ID: 31118895	2019
Biophysical interactions, docking studies and cytotoxic potential of a novel propofol-linolenate: a multi-technique approach. Journal of biomolecular structure & dynamics\| PubMed ID: 31226916	2020
Synthesis and antihepatotoxic activity of dihydropyrimidinone derivatives linked with 1,4-benzodioxane. Drug design, development and therapy\| PubMed ID: 31409973	2019
Therapeutic potential of functionalized siRNA nanoparticles on regression of liver cancer in experimental mice. Scientific reports\| PubMed ID: 31676815	2019
Novel sulindac derivatives: synthesis, characterisation, evaluation of antioxidant, analgesic, anti-inflammatory, ulcerogenic and COX-2 inhibition activity. Journal of enzyme inhibition and medicinal chemistry\| PubMed ID: 32238055	2020
Interaction of an abiraterone with calf thymus DNA: Investigation with spectroscopic technique and modelling studies. Bioorganic chemistry\| PubMed ID: 32470763	2020
Synthesis of Novel Sulfamethaoxazole 4-Thiazolidinone Hybrids and Their Biological Evaluation. Molecules (Basel, Switzerland)\| PubMed ID: 32781534	2020
Enhanced Efficacy of Thiosemicarbazone Derivative-Encapsulated Fibrin Liposomes against Candidiasis in Murine Model. Pharmaceutics\| PubMed ID: 33806702	2021
Potential cytotoxicity of silver nanoparticles: Stimulation of autophagy and mitochondrial dysfunction in cardiac cells. Saudi journal of biological sciences\| PubMed ID: 34025162	2021
A Validated, Rapid and Cost-Efficient HPTLC Method for Quantification of Gamma-Linolenic Acid in Borage Oil and Evaluation of Antioxidant Activity. Journal of chromatographic science\| PubMed ID: 34080615	2022
Formulation Development, In Vitro and In Vivo Evaluation of Topical Hydrogel Formulation of Econazole Nitrate-Loaded β-Cyclodextrin Nanosponges. Journal of pharmaceutical sciences\| PubMed ID: 34293406	2021
Pomegranate peel induced biogenic synthesis of silver nanoparticles and their multifaceted potential against intracellular pathogen and cancer. Saudi journal of biological sciences\| PubMed ID: 34354399	2021
Beneficial Effects of Anticoagulants on the Clinical Outcomes of COVID-19 Patients. Antibiotics (Basel, Switzerland)\| PubMed ID: 34827332	2021
Production and Characterization of Cross-Linked Aggregates of CCR11 Thermoalkaliphilic Recombinant Lipase. Molecules (Basel, Switzerland)\| PubMed ID: 34946651	2021
Interaction Characterization of a Tyrosine Kinase Inhibitor Erlotinib with a Model Transport Protein in the Presence of Quercetin: A Drug-Protein and Drug-Drug Interaction Investigation Usin... Molecules (Basel, Switzerland)\| PubMed ID: 35209054	2022
Codon Usage Analysis of Pro-Apoptotic Bim Gene Isoforms. Journal of Alzheimer's disease : JAD\| PubMed ID: 35253767	2022
Molecular Diagnostic of Ochratoxin A With Specific Aptamers in Corn and Groundnut via Fabrication of a Microfluidic Device. Frontiers in nutrition\| PubMed ID: 35399674	2022
Antifungal Cationic Nanoemulsion Ferrying Miconazole Nitrate with Synergism to Control Fungal Infections: , , and Evaluations. ACS omega\| PubMed ID: 35474838	2022
Microfluidic paper device for rapid detection of aflatoxin B1 using an aptamer based colorimetric assay. RSC advances\| PubMed ID: 35496625	2020
Risk of Malignancy in Breast FNAB Categories, Classified According to the Newly Proposed International Academy of Cytology (IAC) Yokohama System. Cancer management and research\| PubMed ID: 35573260	2022
Expression Pattern and Prognostic Significance of Chemokines in Breast cancer: An Integrated Bioinformatics Analysis. Clinical breast cancer\| PubMed ID: 35585016	2022
Role of Therapeutic Plasmapheresis in SARS-CoV-2 Induced Cytokine Release Syndrome: A Retrospective Cohort Study on COVID-19 Patients. International journal of general medicine\| PubMed ID: 35585996	2022
Association Mechanism and Conformational Changes in Trypsin on Its Interaction with Atrazine: A Multi- Spectroscopic and Biochemical Study with Computational Approach. International journal of molecular sciences\| PubMed ID: 35628445	2022
Enzyme mediated transformation of CO into calcium carbonate using purified microbial carbonic anhydrase. Environmental research\| PubMed ID: 35640707	2022
Ketoconazole-Loaded Cationic Nanoemulsion: -- Evaluations to Control Cutaneous Fungal Infections. ACS omega\| PubMed ID: 35721949	2022
Isolation, Characterization, and Single-Crystal X-ray Analysis of Lantabetulic Acid from : Insights into HSA and BSA Binding Interactions, with In-Silico Study. ACS omega\| PubMed ID: 39346876	2024
Determination of anticancer potential of a novel pharmacologically active thiosemicarbazone derivative against colorectal cancer cell lines. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society\| PubMed ID: 35812146	2022
A comprehensive genomic study, mutation screening, phylogenetic and statistical analysis of SARS-CoV-2 and its variant omicron among different countries. Journal of infection and public health\| PubMed ID: 35839568	2022
5-Fluorouracil and Curcumin Combination Coated with Pectin and Its Strategy towards Titanium Dioxide, Dimethylhydrazine Colorectal Cancer Model with the Evaluation of the Blood Parameters. Polymers\| PubMed ID: 35890644	2022
Effect of Phyto-Assisted Synthesis of Magnesium Oxide Nanoparticles (MgO-NPs) on Bacteria and the Root-Knot Nematode. Bioinorganic chemistry and applications\| PubMed ID: 35979185	2022
Codon Pattern and Compositional Constraints Determination of Genes Associated with Chronic Periodontitis. Genes\| PubMed ID: 36360171	2022
Codon Usage and Context Analysis of Genes Modulated during SARS-CoV-2 Infection and Dental Inflammation. Vaccines\| PubMed ID: 36366382	2022
An investigation of codon usage pattern analysis in pancreatitis associated genes. BMC genomic data\| PubMed ID: 36434531	2022
Author Correction: Therapeutic potential of functionalized siRNA nanoparticles on regression of liver cancer in experimental mice. Scientific reports\| PubMed ID: 36494417	2022
Synthesis and characterization of copper oxide nanoparticles: its influence on corn (Z. mays) and wheat (Triticum aestivum) plants by inoculation of Bacillus subtilis. Environmental science and pollution research international\| PubMed ID: 36571685	2023
Synonymous Codon Variant Analysis for Autophagic Genes Dysregulated in Neurodegeneration. Molecular neurobiology\| PubMed ID: 36637744	2023
Insights into Synonymous Codon Usage Bias in Hepatitis C Virus and Its Adaptation to Hosts. Pathogens (Basel, Switzerland)\| PubMed ID: 36839597	2023
A Synthetic Biology Approach for Vaccine Candidate Design against Delta Strain of SARS-CoV-2 Revealed Disruption of Favored Codon Pair as a Better Strategy over Using Rare Codons. Vaccines\| PubMed ID: 36851364	2023
The simultaneous quantification of Sitagliptin and Irbesartan in rat plasma using the validated LC-MS/MS method is applied to a pharmacokinetic study. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences\| PubMed ID: 36958118	2023
Grass-Shaped Zinc Oxide Nanoparticles Synthesized by the Sol-Gel Process and Their Antagonistic Properties towards the Biotrophic Parasite, . Bioinorganic chemistry and applications\| PubMed ID: 37009336	2023
New Insight into Mechanisms of Cardiovascular Diseases: An Integrative Analysis Approach to Identify TheranoMiRNAs. International journal of molecular sciences\| PubMed ID: 37047756	2023
Mechanistic inhibition of Monkeypox and Marburg virus infection by O-rhamnosides and Kaempferol-o-rhamnosides derivatives: a new-fangled computational approach. Frontiers in cellular and infection microbiology\| PubMed ID: 37293201	2023
Assessment of the Antioxidant and Anti-inflammatory Properties of Aqueous Extract of Rosa sempervirens Leaves. Cellular and molecular biology (Noisy-le-Grand, France)\| PubMed ID: 37300666	2023
Self-Assembling Nanoarchitectonics of Twisted Nanofibers of Fluorescent Amphiphiles as Chemo-Resistive Sensor for Methanol Detection. Gels (Basel, Switzerland)\| PubMed ID: 37367114	2023
The effect of ascorbic acid and cranberry on the bond strength, surface roughness, and surface hardness of bleached enamel with hydrogen peroxide and zinc phthalocyanine activated by photody... Photodiagnosis and photodynamic therapy\| PubMed ID: 37390856	2023
Molecular characterization of azoreductase and its potential for the decolorization of Remazol Red R and Acid Blue 29. Environmental pollution (Barking, Essex : 1987)\| PubMed ID: 37499970	2023
Vaccinomics-based next-generation multi-epitope chimeric vaccine models prediction against hierarchical subtractive proteomics and immunoinformatics approach. Frontiers in immunology\| PubMed ID: 37781384	2023
Pancreatic regenerative potential of manuka honey evidenced through pancreatic histology and levels of transcription factors in diabetic rat model. Heliyon\| PubMed ID: 37809953	2023
Bacterial mediated green synthesis of silver nanoparticles and their antibacterial and antifungal activities against drug-resistant pathogens. Royal Society open science\| PubMed ID: 37885988	2023
Development of a new inhaled swellable microsphere system for the dual delivery of naringenin-loaded solid lipid nanoparticles and doxofylline for the treatment of asthma. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences\| PubMed ID: 37977235	2024
Evaluation of the cytotoxicity, antioxidant activity, and molecular docking of biogenic zinc oxide nanoparticles derived from pumpkin seeds. Microscopy research and technique\| PubMed ID: 38018343	2024
Exploring the Gyrase Complex and Human Topoisomerase: Potential Target for Molecular Docking and Biological Studies with Substituted Polychloroaniline. ACS omega\| PubMed ID: 38046322	2023
designing of multiepitope-based-peptide (MBP) vaccine against MAPK protein express for Alzheimer's disease in Zebrafish. Heliyon\| PubMed ID: 38058625	2023
Bioremediation of hydrocarbon by co-culturing of biosurfactant-producing bacteria in microbial fuel cell with FeO-modified anode. Journal of environmental management\| PubMed ID: 38100858	2024
Mental health and sleep disturbances among Ukrainian refugees in the context of Russian-Ukrainian war: A preliminary result from online-survey. Sleep medicine\| PubMed ID: 38104463	2024
Synthesis and analysis of silica nanocarriers for pectinase immobilization: Enhancing enzymatic stability for continuous industrial applications. Heliyon\| PubMed ID: 38169865	2024
Identification of the myxobacterial secondary metabolites Aurachin A and Soraphinol A as promising inhibitors of thymidylate kinase of the Monkeypox virus. Molecular diversity\| PubMed ID: 38183513	2024
Phytochemical characterization and anti-arthritic potential of leaves extract: In-vivo and in-silico approach. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society\| PubMed ID: 38192284	2023
Natural products from Streptomyces spp. as potential inhibitors of the major factors (holoRdRp and nsp13) for SARS-CoV-2 replication: an in silico approach. Archives of microbiology\| PubMed ID: 38305873	2024
Molecular Dissection of Herpes Simplex Virus Type 1 to Elucidate Molecular Mechanisms Behind Latency and Comparison of Its Codon Usage Patterns with Genes Modulated During Alzheimer's Diseas... Journal of Alzheimer's disease : JAD\| PubMed ID: 38306057	2024
Synthesis, characterization, pharmacological and computational evaluation of hyaluronic acid modified chebulinic acid encapsulated chitosan nanocomposite for cancer therapy. International journal of biological macromolecules\| PubMed ID: 38367777	2024
Efficacy of a vaginal suppository formulation prepared with (Lam.) Willd. gum and (L.) J. Presl. in heavy menstrual bleeding analyzed using a machine learning technique. Frontiers in pharmacology\| PubMed ID: 38410133	2024
Molecular insights into codon usage analysis of mitochondrial fission and fusion gene: relevance to neurodegenerative diseases. Annals of medicine and surgery (2012)\| PubMed ID: 38463054	2024
Synthetic biology approach revealed enhancement in haeme oxygenase-1 gene expression by codon pair optimization while reduction by codon deoptimization. Annals of medicine and surgery (2012)\| PubMed ID: 38463112	2024
Exploring oral drug delivery: In vitro release and mathematical modeling of hydrophobic drug (Na-L-thyroxine) and its cyclodextrin inclusion complex in chitosan microparticles. International journal of biological macromolecules\| PubMed ID: 38513906	2024
Physicochemical Evaluation and Pharmacological Screening of Fernando Adenophylla Steenis Fruits. Chemistry & biodiversity\| PubMed ID: 38563654	2024
succinate based polyelectrolyte complexes for colon delivery of synbiotic in management of inflammatory bowel disease. Heliyon\| PubMed ID: 38628770	2024
Efficacy and classification of linn seeds with mill oil in uncomplicated pelvic inflammatory disease using machine learning. Frontiers in chemistry\| PubMed ID: 38629105	2024
A combination of generated hydrogen sulfide and nitric oxide activity has a potentiated protectant effect against cisplatin induced nephrotoxicity. Heliyon\| PubMed ID: 38655296	2024
Sustained release delivery of favipiravir through statistically optimized, chemically cross-linked, pH-sensitive, swellable hydrogel. BMC pharmacology & toxicology\| PubMed ID: 38685129	2024
A novel Imidazo[1,2-a]pyridine derivative modulates active KRAS through off-like conformational shifts in switch-I and switch-II regions, mimicking inactive KRAS. International journal of biological macromolecules\| PubMed ID: 38772459	2024
Genetic substructure and host-specific natural selection trend across vaccine-candidate ORF-2 capsid protein of hepatitis-E virus. Journal of viral hepatitis\| PubMed ID: 38804127	2024
The antibacterial efficiency of Chitosan photodynamically activated Phycocyanin, and Morinda Oleifera against S.mutans and the bonding strength between composite resin and caries-affected de... Pakistan journal of medical sciences\| PubMed ID: 38827843	2024
Nanocarrier optimization: Encapsulating Hydrastis canadensis in chitosan nanoparticles for enhanced antibacterial and dye degradation performance. International journal of biological macromolecules\| PubMed ID: 38908618	2024
Optimizing microbial strain selection for pyrethroid biodegradation in contaminated environments through a TOPSIS-based decision-making system. Scientific reports\| PubMed ID: 38942772	2024
Photoactivated rose bengal-doped TiO nanoparticles modified fifth-generation adhesive on the survival rate of Streptococcus mutants and mechanical properties of tooth-colored restorative mat... Microscopy research and technique\| PubMed ID: 39056241	2024
Determination of codon pattern and evolutionary forces acting on genes linked to inflammatory bowel disease. International journal of biological macromolecules\| PubMed ID: 39116987	2024
Computational exploration and molecular dynamic simulation for the discovery of antiviral agents targeting Newcastle disease virus. Microbial pathogenesis\| PubMed ID: 39197691	2024
Exploring water relations and phenological traits of Betula utilis (D. Don) in western Himalayan treeline ecotone. Scientific reports\| PubMed ID: 39242651	2024
On discovery of novel hub genes for ER+ and TN breast cancer types through RNA seq data analyses and classification models. Scientific reports\| PubMed ID: 39242688	2024
Titanium oxide and chitosan nanoparticles loaded in methylene blue activated by photodynamic therapy on caries affected dentin disinfection, bond strength, and smear layer removal efficacy. Photodiagnosis and photodynamic therapy\| PubMed ID: 39341329	2024
In-silico Screening and Synthesis of Benzo[c]Pyridazines Targeting N-Methyl D-Aspartate Glutamate Receptor for the Treatment of Seizures. Chemistry & biodiversity\| PubMed ID: 39363726	2025
Flexible high electrochemical collagen/lignin composite hydrogel for sensing and supercapacitor applications. International journal of biological macromolecules\| PubMed ID: 39368572	2024
Phytochemical investigation and spectral characterization of isolated compounds from (D. Don) M. Roem (syn. Roxb) leaves: evaluation of antioxidant activity and molecular docking analysis. Natural product research\| PubMed ID: 39370978	2024
Author Correction: On discovery of novel hub genes for ER+ and TN breast cancer types through RNA seq data analyses and classification models. Scientific reports\| PubMed ID: 39402118	2024
Development and In Vitro Characterization of Azadirachta Indica Gum Grafted Polyacrylamide Based pH-Sensitive Hydrogels to Improve the Bioavailability of Lansoprazole. Chemistry & biodiversity\| PubMed ID: 39404191	2025
Formulation and evaluation of herbal essential oil based nail lacquer for management of onychomycosis. Journal de mycologie medicale\| PubMed ID: 39520795	2024
Influence of sleep quality, excessive daytime sleepiness, circadian features and motor subtypes on depressive symptoms in Parkinson's disease. Sleep medicine\| PubMed ID: 39561672	2025
Antimicrobial and Hepatoprotective Properties of Pods of (L.) Willd. ex Delile: and Approaches. Dose-response : a publication of International Hormesis Society\| PubMed ID: 39679261	2024
Repurposing of dipeptidyl peptidase FDA-approved drugs in Alzheimer's disease using network pharmacology and in-silico approaches. Computational biology and chemistry\| PubMed ID: 39938415	2025
Insights into genetic architecture and disease associations of genes associated with different human blood group systems using codon usage bias. Journal of biomolecular structure & dynamics\| PubMed ID: 39988946	2025
Whole genome analysis and biocontrol potential of endophytic Bacillus cereus EMS1 against Fusarium wilt in banana. World journal of microbiology & biotechnology\| PubMed ID: 40164911	2025
Whole proteome-integrated and vaccinomics-based next generation mRNA vaccine design against Pseudomonas aeruginosa-A hierarchical subtractive proteomics approach. International journal of biological macromolecules\| PubMed ID: 40174835	2025
In Silico ADMET Studies, Molecular Docking and Molecular Dynamics Simulation of Thiadiazole Derivatives for the Identification of Putative HsaA Monooxygenase Inhibitors. Current medicinal chemistry\| PubMed ID: 40183272	2025
In silico identification of PPARγ agonists from diffractaic acid analogs in prostate cancer: a comprehensive computational approach. 3 Biotech\| PubMed ID: 40546399	2025
Design and evaluation of novel thiazolidinedione-oxadiazole derivatives as potent α-amylase inhibitors for antidiabetic therapy. Journal of computer-aided molecular design\| PubMed ID: 40576740	2025