Verena Jendrossek

Institute for Cell Biology (Cancer Research), University of Duisburg-Essen

Affiliated withUniversity of Duisburg-Essen

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2025

Other Publications

Article	Year
Pharmacokinetics and biodistribution of Erufosine in nude mice--implications for combination with radiotherapy. Radiation oncology (London, England)\| PubMed ID: 19852786	2009
Dihydroartemisinin induces apoptosis by a Bak-dependent intrinsic pathway. Molecular cancer therapeutics\| PubMed ID: 20663933	2010
The Akt-inhibitor Erufosine induces apoptotic cell death in prostate cancer cells and increases the short term effects of ionizing radiation. Radiation oncology (London, England)\| PubMed ID: 21080918	2010
Targeting apoptosis pathways by Celecoxib in cancer. Cancer letters\| PubMed ID: 21345578	2013
The intrinsic apoptosis pathways as a target in anticancer therapy. Current pharmaceutical biotechnology\| PubMed ID: 22423614	2012
The action of small GTPases Rab11 and Rab25 in vesicle trafficking during cell migration. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 22613965	2012
Thorax irradiation triggers a local and systemic accumulation of immunosuppressive CD4+ FoxP3+ regulatory T cells. Radiation oncology (London, England)\| PubMed ID: 24766907	2014
Dihydroartemisinin is a Hypoxia-Active Anti-Cancer Drug in Colorectal Carcinoma Cells. Frontiers in oncology\| PubMed ID: 24904829	2014
Nestin(+) tissue-resident multipotent stem cells contribute to tumor progression by differentiating into pericytes and smooth muscle cells resulting in blood vessel remodeling. Frontiers in oncology\| PubMed ID: 25019063	2014
Regulatory T cell-derived adenosine induces dendritic cell migration through the Epac-Rap1 pathway. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 25780038	2015
Prognostic model for long-term survival of locally advanced non-small-cell lung cancer patients after neoadjuvant radiochemotherapy and resection integrating clinical and histopathologic fac... BMC cancer\| PubMed ID: 25943191	2015
Therapy with Multipotent Mesenchymal Stromal Cells Protects Lungs from Radiation-Induced Injury and Reduces the Risk of Lung Metastasis. Antioxidants & redox signaling\| PubMed ID: 26066676	2016
Covalent-Allosteric Kinase Inhibitors. Angewandte Chemie (International ed. in English)\| PubMed ID: 26110718	2015
The Focinator - a new open-source tool for high-throughput foci evaluation of DNA damage. Radiation oncology (London, England)\| PubMed ID: 26238507	2015
RHAMM splice variants confer radiosensitivity in human breast cancer cell lines. Oncotarget\| PubMed ID: 26870892	2016
Extracellular Adenosine Production by ecto-5'-Nucleotidase (CD73) Enhances Radiation-Induced Lung Fibrosis. Cancer research\| PubMed ID: 26921334	2016
Role of SGK1 for fatty acid uptake, cell survival and radioresistance of NCI-H460 lung cancer cells exposed to acute or chronic cycling severe hypoxia. Radiation oncology (London, England)\| PubMed ID: 27251632	2016
Mesenchymal Stem Cell Therapy Protects Lungs from Radiation-Induced Endothelial Cell Loss by Restoring Superoxide Dismutase 1 Expression. Antioxidants & redox signaling\| PubMed ID: 27572073	2017
Down-Regulation of CD62L Shedding in T Cells by CD39 Regulatory T Cells Leads to Defective Sensitization in Contact Hypersensitivity Reactions. The Journal of investigative dermatology\| PubMed ID: 27623510	2017
Investigation on tissue specific effects of pro-apoptotic micro RNAs revealed miR-147b as a potential biomarker in ovarian cancer prognosis. Oncotarget\| PubMed ID: 27821806	2017
Genomic amplification of Fanconi anemia complementation group A (FancA) in head and neck squamous cell carcinoma (HNSCC): Cellular mechanisms of radioresistance and clinical relevance. Cancer letters\| PubMed ID: 27867017	2017
Progression-related loss of stromal Caveolin 1 levels fosters the growth of human PC3 xenografts and mediates radiation resistance. Scientific reports\| PubMed ID: 28112237	2017
Hypoxia Enhances Immunosuppression by Inhibiting CD4+ Effector T Cell Function and Promoting Treg Activity. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology\| PubMed ID: 28278498	2017
The Focinator v2-0 - Graphical Interface, Four Channels, Colocalization Analysis and Cell Phase Identification. Radiation research\| PubMed ID: 28492345	2017
Modeling DNA damage-induced pneumopathy in mice: insight from danger signaling cascades. Radiation oncology (London, England)\| PubMed ID: 28836991	2017
Inhibition of Radiation-Induced Ccl2 Signaling Protects Lungs from Vascular Dysfunction and Endothelial Cell Loss. Antioxidants & redox signaling\| PubMed ID: 29463096	2019
New Insights into Protein Kinase B/Akt Signaling: Role of Localized Akt Activation and Compartment-Specific Target Proteins for the Cellular Radiation Response. Cancers\| PubMed ID: 29562639	2018
The Mitochondrial Citrate Carrier (SLC25A1) Sustains Redox Homeostasis and Mitochondrial Metabolism Supporting Radioresistance of Cancer Cells With Tolerance to Cycling Severe Hypoxia. Frontiers in oncology\| PubMed ID: 29888201	2018
Restraining Akt1 Phosphorylation Attenuates the Repair of Radiation-Induced DNA Double-Strand Breaks and Reduces the Survival of Irradiated Cancer Cells. International journal of molecular sciences\| PubMed ID: 30065170	2018
Relating Linear Energy Transfer to the Formation and Resolution of DNA Repair Foci After Irradiation with Equal Doses of X-ray Photons, Plateau, or Bragg-Peak Protons. International journal of molecular sciences\| PubMed ID: 30486506	2018
High-throughput Evaluation of Protein Migration and Localization after Laser Micro-Irradiation. Scientific reports\| PubMed ID: 30816253	2019
Progression-Related Loss of Stromal Caveolin 1 Levels Mediates Radiation Resistance in Prostate Carcinoma via the Apoptosis Inhibitor TRIAP1. Journal of clinical medicine\| PubMed ID: 30871022	2019
Targeting the Immunomodulatory CD73/Adenosine System to Improve the Therapeutic Gain of Radiotherapy. Frontiers in immunology\| PubMed ID: 31024543	2019
Impact of Cancer-Associated Fibroblast on the Radiation-Response of Solid Xenograft Tumors. Frontiers in molecular biosciences\| PubMed ID: 31475157	2019
Implementation of the Chick Chorioallantoic Membrane (CAM) Model in Radiation Biology and Experimental Radiation Oncology Research. Cancers\| PubMed ID: 31591362	2019
Proton Irradiation Increases the Necessity for Homologous Recombination Repair Along with the Indispensability of Non-Homologous End Joining. Cells\| PubMed ID: 32260562	2020
Caveolin-1 regulates the ASMase/ceramide-mediated radiation response of endothelial cells in the context of tumor-stroma interactions. Cell death & disease\| PubMed ID: 32273493	2020
Cellular Senescence in the Lung: The Central Role of Senescent Epithelial Cells. International journal of molecular sciences\| PubMed ID: 32384619	2020
Oncometabolites and the response to radiotherapy. Radiation oncology (London, England)\| PubMed ID: 32799884	2020
The vascular nature of lung-resident mesenchymal stem cells. Stem cells translational medicine\| PubMed ID: 32830458	2021
Host CD39 Deficiency Affects Radiation-Induced Tumor Growth Delay and Aggravates Radiation-Induced Normal Tissue Toxicity. Frontiers in oncology\| PubMed ID: 33194619	2020
A New Twist in Protein Kinase B/Akt Signaling: Role of Altered Cancer Cell Metabolism in Akt-Mediated Therapy Resistance. International journal of molecular sciences\| PubMed ID: 33202866	2020
Activation of anti-oxidant Keap1/Nrf2 pathway modulates efficacy of dihydroartemisinin-based monotherapy and combinatory therapy with ionizing radiation. Free radical biology & medicine\| PubMed ID: 33775773	2021
The Biomarker Potential of Caveolin-1 in Penile Cancer. Frontiers in oncology\| PubMed ID: 33868995	2021
Metabolic reprograming of antioxidant defense: a precision medicine perspective for radiotherapy of lung cancer? Biochemical Society transactions\| PubMed ID: 34110407	2021
Metformin Protects against Radiation-Induced Acute Effects by Limiting Senescence of Bronchial-Epithelial Cells. International journal of molecular sciences\| PubMed ID: 34209135	2021
Bcl-2/Bcl-xL inhibitor ABT-263 overcomes hypoxia-driven radioresistence and improves radiotherapy. Cell death & disease\| PubMed ID: 34257274	2021
Loss of pro-apoptotic Bax and Bak increases resistance to dihydroartemisinin-mediated cytotoxicity in normoxia but not in hypoxia in HCT116 colorectal cancer cells. Free radical biology & medicine\| PubMed ID: 34403740	2021
Metabolism of cancer cells commonly responds to irradiation by a transient early mitochondrial shutdown. iScience\| PubMed ID: 34825138	2021
Adaptation to Chronic-Cycling Hypoxia Renders Cancer Cells Resistant to MTH1-Inhibitor Treatment Which Can Be Counteracted by Glutathione Depletion. Cells\| PubMed ID: 34831264	2021
Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinoma. Cell death & disease\| PubMed ID: 34911941	2021
Stromal Fibroblasts Counteract the Caveolin-1-Dependent Radiation Response of LNCaP Prostate Carcinoma Cells. Frontiers in oncology\| PubMed ID: 35155239	2022
Nintedanib and Dasatinib Treatments Induce Protective Autophagy as a Potential Resistance Mechanism in MPM Cells. Frontiers in cell and developmental biology\| PubMed ID: 35392170	2022
Correction to: Bcl-2/Bcl-xL inhibitor ABT-263 overcomes hypoxia-driven radioresistence and improves radiotherapy. Cell death & disease\| PubMed ID: 35440079	2022
Accumulation of oncometabolite D-2-Hydroxyglutarate by SLC25A1 inhibition: A metabolic strategy for induction of HR-ness and radiosensitivity. Cell death & disease\| PubMed ID: 35869047	2022
CD9- and CD81-positive extracellular vesicles provide a marker to monitor glioblastoma cell response to photon-based and proton-based radiotherapy. Frontiers in oncology\| PubMed ID: 36203458	2022
A Sequential Targeting Strategy Interrupts AKT-Driven Subclone-Mediated Progression in Glioblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 36239995	2023
CD47 restricts antiviral function of alveolar macrophages during influenza virus infection. iScience\| PubMed ID: 36437873	2022
Combined radiation- and immune checkpoint-inhibitor-induced pneumonitis - The challenge to predict and detect overlapping immune-related adverse effects from evolving laboratory biomarkers a... Neoplasia (New York, N.Y.)\| PubMed ID: 37011458	2023
Comparative transcriptomic and proteomic signature of lung alveolar macrophages reveals the integrin CD11b as a regulatory hub during pneumococcal pneumonia infection. Frontiers in immunology\| PubMed ID: 37790937	2023
α-Ketoglutarate supplementation and NAD+ modulation enhance metabolic rewiring and radiosensitization in SLC25A1 inhibited cancer cells. Cell death discovery\| PubMed ID: 38225236	2024
CD73/adenosine dynamics in treatment-induced pneumonitis: balancing efficacy with risks of adverse events in combined radio-immunotherapies. Frontiers in cell and developmental biology\| PubMed ID: 39872847	2024
Diagnosis and treatment of radiation induced pneumonitis in patients with lung cancer: An ESTRO clinical practice guideline. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology\| PubMed ID: 40185160	2025