Diana Klein

Institute for Cell Biology (Cancer Research), University of Duisburg-Essen

Affiliated withUniversity of Duisburg-Essen

Research Area

Biography

Diana Klein has not added Biography.
If you are Diana Klein and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2025

Other Publications

Article	Year
Vascular wall-resident CD44+ multipotent stem cells give rise to pericytes and smooth muscle cells and contribute to new vessel maturation. PloS one\| PubMed ID: 21637782	2011
Tumor vessel stabilization and remodeling by anti-angiogenic therapy with bevacizumab. Histochemistry and cell biology\| PubMed ID: 22193946	2012
Connexin 31 (GJB3) deficiency in mouse trophoblast stem cells alters giant cell differentiation and leads to loss of oxygen sensing. Biology of reproduction\| PubMed ID: 22623621	2012
Hox genes are involved in vascular wall-resident multipotent stem cell differentiation into smooth muscle cells. Scientific reports\| PubMed ID: 24145756	2013
Nestin(+) tissue-resident multipotent stem cells contribute to tumor progression by differentiating into pericytes and smooth muscle cells resulting in blood vessel remodeling. Frontiers in oncology\| PubMed ID: 25019063	2014
Therapy with Multipotent Mesenchymal Stromal Cells Protects Lungs from Radiation-Induced Injury and Reduces the Risk of Lung Metastasis. Antioxidants & redox signaling\| PubMed ID: 26066676	2016
CCN1 (CYR61) and CCN3 (NOV) signaling drives human trophoblast cells into senescence and stimulates migration properties. Cell adhesion & migration\| PubMed ID: 26744771	2016
RHAMM splice variants confer radiosensitivity in human breast cancer cell lines. Oncotarget\| PubMed ID: 26870892	2016
Vascular Wall-Resident Multipotent Stem Cells of Mesenchymal Nature within the Process of Vascular Remodeling: Cellular Basis, Clinical Relevance, and Implications for Stem Cell Therapy. Stem cells international\| PubMed ID: 26880936	2016
Extracellular Adenosine Production by ecto-5'-Nucleotidase (CD73) Enhances Radiation-Induced Lung Fibrosis. Cancer research\| PubMed ID: 26921334	2016
Angelman syndrome-derived neurons display late onset of paternal UBE3A silencing. Scientific reports\| PubMed ID: 27484051	2016
Mesenchymal Stem Cell Therapy Protects Lungs from Radiation-Induced Endothelial Cell Loss by Restoring Superoxide Dismutase 1 Expression. Antioxidants & redox signaling\| PubMed ID: 27572073	2017
Genomic amplification of Fanconi anemia complementation group A (FancA) in head and neck squamous cell carcinoma (HNSCC): Cellular mechanisms of radioresistance and clinical relevance. Cancer letters\| PubMed ID: 27867017	2017
Progression-related loss of stromal Caveolin 1 levels fosters the growth of human PC3 xenografts and mediates radiation resistance. Scientific reports\| PubMed ID: 28112237	2017
In Vitro Generation of Vascular Wall-Resident Multipotent Stem Cells of Mesenchymal Nature from Murine Induced Pluripotent Stem Cells. Stem cell reports\| PubMed ID: 28366456	2017
iPSCs-based generation of vascular cells: reprogramming approaches and applications. Cellular and molecular life sciences : CMLS\| PubMed ID: 29243171	2018
Inhibition of Radiation-Induced Ccl2 Signaling Protects Lungs from Vascular Dysfunction and Endothelial Cell Loss. Antioxidants & redox signaling\| PubMed ID: 29463096	2019
Caveolin-1, cancer and therapy resistance. International journal of cancer\| PubMed ID: 29524224	2018
Current Strategies to Generate Human Mesenchymal Stem Cells In Vitro. Stem cells international\| PubMed ID: 30224922	2018
The Tumor Vascular Endothelium as Decision Maker in Cancer Therapy. Frontiers in oncology\| PubMed ID: 30250827	2018
Targeting of BRM Sensitizes -Mutant Lung Cancer Cell Lines to Radiotherapy. Molecular cancer therapeutics\| PubMed ID: 30478150	2019
Progression-Related Loss of Stromal Caveolin 1 Levels Mediates Radiation Resistance in Prostate Carcinoma via the Apoptosis Inhibitor TRIAP1. Journal of clinical medicine\| PubMed ID: 30871022	2019
Impact of Cancer-Associated Fibroblast on the Radiation-Response of Solid Xenograft Tumors. Frontiers in molecular biosciences\| PubMed ID: 31475157	2019
Direct conversion of human fibroblasts into therapeutically active vascular wall-typical mesenchymal stem cells. Cellular and molecular life sciences : CMLS\| PubMed ID: 31712992	2020
Caveolin-1 regulates the ASMase/ceramide-mediated radiation response of endothelial cells in the context of tumor-stroma interactions. Cell death & disease\| PubMed ID: 32273493	2020
Cellular Senescence in the Lung: The Central Role of Senescent Epithelial Cells. International journal of molecular sciences\| PubMed ID: 32384619	2020
Improved Isolation of Human Vascular Wall-Resident Mesenchymal Stem Cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 32474868	2020
In Vitro Generation of Vascular Wall-Typical Mesenchymal Stem Cells (VW-MSC) from Murine Induced Pluripotent Stem Cells Through VW-MSC-Specific Gene Transfer. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 32474869	2020
The vascular nature of lung-resident mesenchymal stem cells. Stem cells translational medicine\| PubMed ID: 32830458	2021
Lung Multipotent Stem Cells of Mesenchymal Nature: Cellular Basis, Clinical Relevance, and Implications for Stem Cell Therapy. Antioxidants & redox signaling\| PubMed ID: 33167666	2021
Host CD39 Deficiency Affects Radiation-Induced Tumor Growth Delay and Aggravates Radiation-Induced Normal Tissue Toxicity. Frontiers in oncology\| PubMed ID: 33194619	2020
Enhanced antitumoral activity of TLR7 agonists via activation of human endogenous retroviruses by HDAC inhibitors. Communications biology\| PubMed ID: 33658617	2021
GPR15 Facilitates Recruitment of Regulatory T Cells to Promote Colorectal Cancer. Cancer research\| PubMed ID: 33727229	2021
The Biomarker Potential of Caveolin-1 in Penile Cancer. Frontiers in oncology\| PubMed ID: 33868995	2021
Metformin Protects against Radiation-Induced Acute Effects by Limiting Senescence of Bronchial-Epithelial Cells. International journal of molecular sciences\| PubMed ID: 34209135	2021
Bcl-2/Bcl-xL inhibitor ABT-263 overcomes hypoxia-driven radioresistence and improves radiotherapy. Cell death & disease\| PubMed ID: 34257274	2021
Lung-Resident Mesenchymal Stem Cell Fates within Lung Cancer. Cancers\| PubMed ID: 34572864	2021
Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinoma. Cell death & disease\| PubMed ID: 34911941	2021
Stromal Fibroblasts Counteract the Caveolin-1-Dependent Radiation Response of LNCaP Prostate Carcinoma Cells. Frontiers in oncology\| PubMed ID: 35155239	2022
Correction to: Bcl-2/Bcl-xL inhibitor ABT-263 overcomes hypoxia-driven radioresistence and improves radiotherapy. Cell death & disease\| PubMed ID: 35440079	2022
HOX genes in stem cells: Maintaining cellular identity and regulation of differentiation. Frontiers in cell and developmental biology\| PubMed ID: 36176275	2022
Protein Levels of Anti-Apoptotic Mcl-1 and the Deubiquitinase USP9x Are Cooperatively Upregulated during Prostate Cancer Progression and Limit Response of Prostate Cancer Cells to Radiothera... Cancers\| PubMed ID: 37173959	2023
Similar additive effects of doxorubicin in combination with photon or proton irradiation in soft tissue sarcoma models. Frontiers in oncology\| PubMed ID: 37503316	2023
Endothelial Cell Response to Combined Photon or Proton Irradiation with Doxorubicin. International journal of molecular sciences\| PubMed ID: 37629014	2023
Comparative transcriptomic and proteomic signature of lung alveolar macrophages reveals the integrin CD11b as a regulatory hub during pneumococcal pneumonia infection. Frontiers in immunology\| PubMed ID: 37790937	2023
Comparative computational analysis to distinguish mesenchymal stem cells from fibroblasts. Frontiers in immunology\| PubMed ID: 37822926	2023
Non-small cell lung cancer cells and concomitant cancer therapy induce a resistance-promoting phenotype of tumor-associated mesenchymal stem cells. Frontiers in oncology\| PubMed ID: 39011489	2024
Matrix-free human lung organoids derived from induced pluripotent stem cells to model lung injury. Stem cell research & therapy\| PubMed ID: 39696649	2024
Matrix-Free Normal Human Epithelial-Fibroblast 3D Spheroid Cultures for In Vitro Lung Modeling. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 40106147	2025
Free-Floating Human Lung Organoids Derived from Induced Pluripotent Stem Cells. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 40106148	2025
Complex Spheroids as an Alternative: In Vivo-Like 3D Model for Investigating the Impact of Stromal Cells on the Radiation Response of Tumors. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 40172832	2025
Does severe mucositis impair oncological outcome in head and neck cancer patients? A pooled analysis of two prospective studies with long-term follow-up. BMC cancer\| PubMed ID: 40399815	2025