Juliana M. Serpeloni

Laboratory of Mutagenesis and Oncogenetics, State University of Londrina

Affiliated withState University of Londrina

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title	2025

Other Publications

Article	Year
In vivo assessment of DNA damage and protective effects of extracts from Miconia species using the comet assay and micronucleus test. Mutagenesis\| PubMed ID: 18765422	2008
Lutein improves antioxidant defense in vivo and protects against DNA damage and chromosome instability induced by cisplatin. Archives of toxicology\| PubMed ID: 20683581	2010
An evaluation, using the comet assay and the micronucleus test, of the antigenotoxic effects of chlorophyll b in mice. Mutation research\| PubMed ID: 21763449	2011
Effects of lutein and chlorophyll b on GSH depletion and DNA damage induced by cisplatin in vivo. Human & experimental toxicology\| PubMed ID: 23821640	2013
Diet carotenoid lutein modulates the expression of genes related to oxygen transporters and decreases DNA damage and oxidative stress in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association\| PubMed ID: 24865317	2014
Chemical and biological characterisation of Machaerium hirtum (Vell.) Stellfeld: absence of cytotoxicity and mutagenicity and possible chemopreventive potential. Mutagenesis\| PubMed ID: 26314304	2016
Antimutagenicity and induction of antioxidant defense by flavonoid rich extract of Myrcia bella Cambess. in normal and tumor gastric cells. Journal of ethnopharmacology\| PubMed ID: 26549270	2015
LDH, proliferation curves and cell cycle analysis are the most suitable assays to identify and characterize new phytotherapeutic compounds. Cytotechnology\| PubMed ID: 27344148	2016
Phytochemical study and evaluation of cytotoxicity, mutagenicity, cell cycle kinetics and gene expression of Bauhinia holophylla (Bong.) Steud. in HepG2 cells in vitro. Cytotechnology\| PubMed ID: 29230630	2018
Selective anticancer effects of Serjania marginata Casar. extract in gastric cells are mediated by antioxidant response. Environmental toxicology\| PubMed ID: 33885224	2021
Aglycone flavonoid brachydin A shows selective cytotoxicity and antitumoral activity in human metastatic prostate (DU145) cancer cells. Cytotechnology\| PubMed ID: 34776627	2021
The Antitumoral/Antimetastatic Action of the Flavonoid Brachydin A in Metastatic Prostate Tumor Spheroids In Vitro Is Mediated by (Parthanatos) PARP-Related Cell Death. Pharmaceutics\| PubMed ID: 35631550	2022
Flavone cirsimarin impairs cell proliferation, migration, and invasion in MCF-7 cells grown in 2D and 3D models. Toxicology in vitro : an international journal published in association with BIBRA\| PubMed ID: 35710092	2022
Anticancer activities of Brachydin C in human prostate tumor cells (DU145) grown in 2D and 3D models: Stimulation of cell death and downregulation of metalloproteinases in spheroids. Chemical biology & drug design\| PubMed ID: 35775856	2022
An Overview Regarding Pharmacogenomics and Biomarkers Discovery: Focus on Breast Cancer. Current topics in medicinal chemistry\| PubMed ID: 35927918	2022
Three-dimensional cell cultures as preclinical models to assess the biological activity of phytochemicals in breast cancer. Toxicology and applied pharmacology\| PubMed ID: 36638973	2023
Association between Polymorphisms of Hemochromatosis (HFE), Blood Lead (Pb) Levels, and DNA Oxidative Damage in Battery Workers. International journal of environmental research and public health\| PubMed ID: 36834208	2023
Chemical characterization of Brazilian savannah Byrsonima species (muricis) and their impact on genomic instability and chemopreventive effects. Mutation research. Genetic toxicology and environmental mutagenesis\| PubMed ID: 37003647	2023
Flavonoid brachydin B decreases viability, proliferation, and migration in human metastatic prostate (DU145) cells grown in 2D and 3D culture models. Toxicology research\| PubMed ID: 37125333	2023
Effects of docetaxel on metastatic prostate (DU-145) carcinoma cells cultured as 2D monolayers and 3D multicellular tumor spheroids. Journal of toxicology and environmental health. Part A\| PubMed ID: 38095149	2024
Polymorphisms in drug-metabolizing genes and urinary bladder cancer susceptibility and prognosis: Possible impacts and future management. Gene\| PubMed ID: 38350514	2024
Production and characterization of rhamnolipids by Pseudomonas aeruginosa isolated in the Amazon region, and potential antiviral, antitumor, and antimicrobial activity. Scientific reports\| PubMed ID: 38472312	2024
Pesticide exposure and oxidative stress generation are linked to poor prognosis outcomes in breast cancer women carrying the allelic variant rs7438135 in the UGT2B7 gene. Journal of biochemical and molecular toxicology\| PubMed ID: 39392214	2024
Genetic polymorphisms, methylation, and expression levels in the GSTP1 and MGMT genes in urothelial bladder tumors. Gene\| PubMed ID: 39706230	2025
Allelic variants in xenobiotic metabolism genes predict susceptibility and worse prognosis of urothelial bladder cancer. Pathology, research and practice\| PubMed ID: 39729958	2025
The rs3757385 polymorphism increases IRF5 expression and systemic nitric oxide metabolites, protecting urothelial bladder cancer patients from recurrence. Molecular biology reports\| PubMed ID: 40580227	2025