asthma-detection-research-based-on-voice-signal-processing-machine

Asthma Detection Research Based on Voice Signal Processing and Machine Learning

To analyze voice signals and identify asthma patients using voice signal analysis and machine learning techniques, we collected clear, low-noise ...

machine-learning-based-cough-tone-classification-diagnostic

Machine Learning-Based Cough Tone Classification: Diagnostic Exploration of Chronic Obstructive Pulmonary Disease and Respiratory Tract Infections

The objective of this study was to develop and evaluate a non-invasive method for distinguishing patients with chronic obstructive pulmonary disease ...

Beijing University of Chinese Medicine

Rationale Obesity is an independent risk factor for the occurrence and development of tumors. Obesity is influenced by signaling of adipokines, which are secreted factors from adipocytes and resident immune cells within adipose tissues that mediate lipid metabolism. More recently, adipokines have been implicated in chronic inflammation as well as in tumor formation and growth. Among them, resistin has received increasing attention in research related to the growth and expansion of solid tumors and hematological cancers through various signaling pathways. Objective and findings We reviewed the physiological, biochemical, and immune functions of adipose tissue, with a focus on the structure and expression of resistin and adipokines within multiple adipose cell types, their signaling pathways and putative effects on tumor cells, as well as their in vivo regulation. Current evidence indicates that adipokines such as resistin act as pro-inflammatory factors to stimulate immune cells which, in turn, promotes tumor angiogenesis, connective tissue proliferation, and matrix fibrosis. Concurrently, in states of metabolic dysfunction and lipotoxicity in obese individuals, the numbers and functions of immune cells are compromised, leading to an immunosuppressive environment that fosters tumor cell survival and weak cancer immune monitoring. Conclusion Adipokines such as resistin are important to the development of obesity-related tumors. Clarifying the roles for obesity-related factors in immune regulation and tumor progression may lead to the discovery of novel anti-tumor strategies for targeting obesity factors such as resistin to limit tumor growth and manage obesity, or both.

Immunological roles for resistin and related adipokines in obesity-associated tumors.

Cardioembolic Stroke (CS) and Atrial Fibrillation (AF) are prevalent diseases that significantly impact the quality of life and impose considerable financial burdens on society. Despite increasing evidence of a significant association between the two diseases, their complex interactions remain inadequately understood. We conducted bioinformatics analysis and employed machine learning techniques to investigate potential shared biomarkers between CS and AF.

ArticleTotal : 2	Year
Publication title	2025
Publication title	2025

Article	Year
Immunological roles for resistin and related adipokines in obesity-associated tumors. International immunopharmacology\| PubMed ID: 39232363	2024
Exploring the shared biomarkers between cardioembolic stroke and atrial fibrillation by WGCNA and machine learning. Frontiers in cardiovascular medicine\| PubMed ID: 39267804	2024

Jingxin Zhang

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